{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T19:15:20Z","timestamp":1791918920741,"version":"4.3.4"},"reference-count":845,"publisher":"American Chemical Society (ACS)","issue":"11","license":[{"start":{"date-parts":[[2022,11,2]],"date-time":"2022-11-02T00:00:00Z","timestamp":1667347200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,11,2]],"date-time":"2022-11-02T00:00:00Z","timestamp":1667347200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,11,2]],"date-time":"2022-11-02T00:00:00Z","timestamp":1667347200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/501100004490","name":"University of Waterloo","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004490","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001804","name":"Canada Research Chairs","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001804","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100022179","name":"Prostate Cancer Fight Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100022179","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000038","name":"Natural Sciences and Engineering Research Council of Canada","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000038","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004489","name":"Mitacs","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004489","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Ontario Graduate Scholarship program"},{"name":"Canada\u2019s Telus Ride for Dad"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ACS Nano"],"published-print":{"date-parts":[[2022,11,22]]},"DOI":"10.1021\/acsnano.2c06337","type":"journal-article","created":{"date-parts":[[2022,11,2]],"date-time":"2022-11-02T14:34:13Z","timestamp":1667399653000},"page":"17497-17551","source":"Crossref","is-referenced-by-count":50,"title":["A Nanomedicine Structure\u2013Activity Framework for Research, Development, and Regulation of Future Cancer Therapies"],"prefix":"10.1021","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2545-2866","authenticated-orcid":true,"given":"Brian","family":"Youden","sequence":"first","affiliation":[{"name":"Department of Biology, University of Waterloo, 200 University Ave. W, Waterloo, Ontario N2L 3G1, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Runqing","family":"Jiang","sequence":"additional","affiliation":[{"name":"Department of Biology, University of Waterloo, 200 University Ave. W, Waterloo, Ontario N2L 3G1, Canada"},{"name":"Department of Medical Physics, Grand River Regional Cancer Centre, Kitchener, Ontario N2G 1G3, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew J.","family":"Carrier","sequence":"additional","affiliation":[{"name":"Department of Chemistry, Cape Breton University, 1250 Grand Lake Road, Sydney, Nova Scotia B1P 6L2, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark R.","family":"Servos","sequence":"additional","affiliation":[{"name":"Department of Biology, University of Waterloo, 200 University Ave. W, Waterloo, Ontario N2L 3G1, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8098-0410","authenticated-orcid":true,"given":"Xu","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Biology, University of Waterloo, 200 University Ave. W, Waterloo, Ontario N2L 3G1, Canada"},{"name":"Department of Chemistry, Cape Breton University, 1250 Grand Lake Road, Sydney, Nova Scotia B1P 6L2, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2022,11,2]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(18)32252-9"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21492"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1016\/j.drudis.2010.08.006"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.3389\/fchem.2020.598100"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1039\/C8NR07769J"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1021\/acs.chemrev.7b00258"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1007\/s11095-016-1958-5"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1016\/j.nantod.2020.101008"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.9b04266"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2020.07.007"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1016\/j.trecan.2017.06.006"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1016\/j.nantod.2020.101019"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1007\/s13346-021-00911-y"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1002\/adhm.202000979"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1038\/s41565-019-0567-y"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1186\/s12645-019-0055-y"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1002\/btm2.10143"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.3390\/pharmaceutics9020012"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1002\/btm2.10246"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.2174\/0929867325666171229141156"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1080\/21655979.2020.1736240"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1080\/17425247.2019.1662786"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.201902652"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1021\/ar9001069"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1016\/j.addr.2008.08.004"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1021\/ja104683w"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201410738"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(19)30326-2"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1007\/s40265-015-0453-3"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1080\/21691401.2019.1709855"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1038\/natrevmats.2017.14"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1007\/s40097-018-0267-4"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.2147\/IJN.S46900"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1002\/wnan.1364"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.2174\/0929867324666170830113755"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1186\/s12935-021-02025-4"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpharm.2019.118814"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1093\/annonc\/mdh097"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.7b05876"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.1c21655"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.1016\/j.addr.2010.04.009"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2011.06.001"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.7b07214"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.1016\/j.addr.2018.07.007"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.1038\/s41563-019-0566-2"},{"key":"ref46\/cit46","doi-asserted-by":"publisher","DOI":"10.1002\/wnan.1665"},{"key":"ref47\/cit47","doi-asserted-by":"publisher","DOI":"10.1208\/s12248-020-00464-x"},{"key":"ref48\/cit48","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-019-11642-7"},{"key":"ref49\/cit49","doi-asserted-by":"publisher","DOI":"10.1016\/j.addr.2012.09.037"},{"key":"ref50\/cit50","doi-asserted-by":"publisher","DOI":"10.1080\/10717544.2016.1177136"},{"key":"ref51\/cit51","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2013.00143"},{"key":"ref52\/cit52","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2015.00286"},{"key":"ref53\/cit53","doi-asserted-by":"publisher","DOI":"10.1038\/nnano.2015.330"},{"key":"ref54\/cit54","doi-asserted-by":"publisher","DOI":"10.1093\/annonc\/mdl477"},{"key":"ref55\/cit55","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0185654"},{"key":"ref56\/cit56","doi-asserted-by":"publisher","DOI":"10.3892\/ol.2016.4740"},{"key":"ref57\/cit57","doi-asserted-by":"publisher","DOI":"10.1021\/acs.chemrev.8b00626"},{"key":"ref58\/cit58","doi-asserted-by":"publisher","DOI":"10.1038\/nnano.2009.242"},{"key":"ref59\/cit59","doi-asserted-by":"publisher","DOI":"10.1021\/acscentsci.7b00574"},{"key":"ref60\/cit60","doi-asserted-by":"publisher","DOI":"10.3389\/fchem.2021.630969"},{"key":"ref61\/cit61","doi-asserted-by":"publisher","DOI":"10.1002\/smll.200800261"},{"key":"ref62\/cit62","doi-asserted-by":"publisher","DOI":"10.1016\/j.nantod.2020.100946"},{"key":"ref63\/cit63","doi-asserted-by":"publisher","DOI":"10.1039\/C4NR00708E"},{"key":"ref64\/cit64","doi-asserted-by":"publisher","DOI":"10.1039\/D0CS00215A"},{"key":"ref65\/cit65","doi-asserted-by":"publisher","DOI":"10.1039\/D1CS00427A"},{"key":"ref66\/cit66","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201805664"},{"key":"ref67\/cit67","doi-asserted-by":"publisher","DOI":"10.1002\/adma.201802244"},{"key":"ref68\/cit68","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2020.08.036"},{"key":"ref69\/cit69","doi-asserted-by":"publisher","DOI":"10.1039\/C7CS00316A"},{"key":"ref70\/cit70","doi-asserted-by":"publisher","DOI":"10.1016\/j.addr.2015.12.012"},{"key":"ref71\/cit71","doi-asserted-by":"publisher","DOI":"10.7150\/thno.22172"},{"key":"ref72\/cit72","doi-asserted-by":"publisher","DOI":"10.1016\/j.clon.2014.10.005"},{"key":"ref73\/cit73","doi-asserted-by":"publisher","DOI":"10.1016\/j.clon.2016.11.011"},{"key":"ref74\/cit74","volume-title":"Radiobiology for the Radiologist: Seventh ed.","author":"Hall E. J.","year":"2012"},{"key":"ref75\/cit75","doi-asserted-by":"publisher","DOI":"10.3389\/fmolb.2014.00024"},{"key":"ref76\/cit76","doi-asserted-by":"publisher","DOI":"10.1038\/sj.onc.1206663"},{"key":"ref77\/cit77","doi-asserted-by":"publisher","DOI":"10.1016\/j.radonc.2017.07.007"},{"key":"ref78\/cit78","doi-asserted-by":"publisher","DOI":"10.1038\/nature12625"},{"key":"ref79\/cit79","doi-asserted-by":"publisher","DOI":"10.1007\/s00018-016-2210-5"},{"key":"ref80\/cit80","doi-asserted-by":"publisher","DOI":"10.1016\/0360-3016(79)90044-0"},{"key":"ref81\/cit81","doi-asserted-by":"publisher","DOI":"10.1038\/ncponc0714"},{"key":"ref82\/cit82","doi-asserted-by":"publisher","DOI":"10.1038\/nrclinonc.2012.203"},{"key":"ref83\/cit83","doi-asserted-by":"publisher","DOI":"10.1053\/srao.2003."},{"key":"ref84\/cit84","doi-asserted-by":"publisher","DOI":"10.1016\/j.semradonc.2005.08.001"},{"key":"ref85\/cit85","doi-asserted-by":"publisher","DOI":"10.1586\/14737140.2.4.409"},{"key":"ref86\/cit86","doi-asserted-by":"publisher","DOI":"10.1080\/15216540701636287"},{"key":"ref87\/cit87","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-18-2466"},{"key":"ref88\/cit88","doi-asserted-by":"publisher","DOI":"10.1088\/1361-6560\/ab9159"},{"key":"ref89\/cit89","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijrobp.2015.09.032"},{"key":"ref90\/cit90","doi-asserted-by":"publisher","DOI":"10.21037\/1514"},{"key":"ref91\/cit91","doi-asserted-by":"publisher","DOI":"10.1088\/0031-9155\/49\/18\/N03"},{"key":"ref92\/cit92","doi-asserted-by":"publisher","DOI":"10.1259\/bjr\/13169882"},{"key":"ref93\/cit93","doi-asserted-by":"publisher","DOI":"10.1016\/j.addr.2018.06.024"},{"key":"ref94\/cit94","doi-asserted-by":"publisher","DOI":"10.1001\/amajethics.2019.347"},{"key":"ref95\/cit95","doi-asserted-by":"publisher","DOI":"10.1039\/D0BM00558D"},{"issue":"12","key":"ref96\/cit96","first-page":"742","volume":"42","author":"Ventola C. L.","year":"2017","journal-title":"Pharmacol. Ther."},{"key":"ref97\/cit97","doi-asserted-by":"publisher","DOI":"10.1080\/17425247.2016.1244187"},{"key":"ref98\/cit98","unstructured":"U.S. Food and Drug Administration.\n                      Final Guidance for Industry - Liposome Drug Products: Chemistry,\nManufacturing, and Controls; Human Pharmacokinetics and Bioavailability;\nand Labeling Documentation\n                      ; U.S. FDA, 2018. https:\/\/www.fda.gov\/media\/70837\/download."},{"key":"ref99\/cit99","unstructured":"U.S. Food and Drug Administration.\n                      Final Guidance for Industry - Considering\nWhether an FDA-Regulated\nProduct Involves the Application of Nanotechnology\n                      ; U.S. FDA, 2014. https:\/\/www.fda.gov\/media\/88423\/download."},{"key":"ref100\/cit100","unstructured":"U.S. Food and Drug Administration.\n                      Draft Guidance for Industry - Drug Products,\nIncluding\nBiological Products, That Contain Nanomaterials\n                      ; U.S. FDA, 2017. https:\/\/www.fda.gov\/media\/109910\/download."},{"key":"ref101\/cit101","doi-asserted-by":"publisher","DOI":"10.3389\/fchem.2018.00360"},{"key":"ref102\/cit102","doi-asserted-by":"publisher","DOI":"10.1002\/wnan.1738"},{"key":"ref103\/cit103","doi-asserted-by":"publisher","DOI":"10.1016\/j.cbi.2019.108868"},{"key":"ref104\/cit104","doi-asserted-by":"publisher","DOI":"10.1007\/s00204-012-0837-z"},{"key":"ref105\/cit105","doi-asserted-by":"publisher","DOI":"10.1016\/j.chroma.2022.463520"},{"key":"ref106\/cit106","doi-asserted-by":"publisher","DOI":"10.1208\/s12248-018-0255-0"},{"key":"ref107\/cit107","doi-asserted-by":"publisher","DOI":"10.2760\/59682"},{"key":"ref108\/cit108","doi-asserted-by":"publisher","DOI":"10.1038\/bjc.2014.448"},{"key":"ref109\/cit109","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2019.01369"},{"key":"ref110\/cit110","doi-asserted-by":"publisher","DOI":"10.1007\/s13346-020-00740-5"},{"key":"ref111\/cit111","doi-asserted-by":"publisher","DOI":"10.1007\/s12247-020-09495-5"},{"key":"ref112\/cit112","doi-asserted-by":"publisher","DOI":"10.1021\/acs.accounts.9b00228"},{"key":"ref113\/cit113","doi-asserted-by":"publisher","DOI":"10.1016\/j.addr.2018.05.008"},{"key":"ref114\/cit114","doi-asserted-by":"publisher","DOI":"10.2217\/nnm-2018-0120"},{"key":"ref115\/cit115","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2015.15572"},{"key":"ref116\/cit116","doi-asserted-by":"publisher","DOI":"10.1038\/s41569-021-00662-w"},{"key":"ref117\/cit117","doi-asserted-by":"publisher","DOI":"10.1016\/j.semcdb.2012.09.014"},{"key":"ref118\/cit118","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2019.108852"},{"key":"ref119\/cit119","doi-asserted-by":"publisher","DOI":"10.1016\/j.yrtph.2017.10.019"},{"key":"ref120\/cit120","doi-asserted-by":"publisher","DOI":"10.1080\/17460441.2019.1621286"},{"key":"ref121\/cit121","doi-asserted-by":"publisher","DOI":"10.1039\/C9EN00785G"},{"key":"ref122\/cit122","doi-asserted-by":"publisher","DOI":"10.1186\/s12989-018-0273-1"},{"key":"ref123\/cit123","doi-asserted-by":"publisher","DOI":"10.1186\/s11671-018-2457-x"},{"key":"ref124\/cit124","doi-asserted-by":"publisher","DOI":"10.1038\/nnano.2015.338"},{"key":"ref125\/cit125","doi-asserted-by":"publisher","DOI":"10.1038\/nrc.2016.108"},{"key":"ref126\/cit126","doi-asserted-by":"publisher","DOI":"10.1038\/s41565-019-0496-9"},{"key":"ref127\/cit127","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.8b07562"},{"key":"ref128\/cit128","doi-asserted-by":"publisher","DOI":"10.1021\/nn3010087"},{"key":"ref129\/cit129","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2015.06.178"},{"key":"ref130\/cit130","doi-asserted-by":"publisher","DOI":"10.1002\/adbi.202000220"},{"key":"ref131\/cit131","doi-asserted-by":"publisher","DOI":"10.1039\/C8CC06473C"},{"key":"ref132\/cit132","doi-asserted-by":"publisher","DOI":"10.2217\/nnm.15.188"},{"key":"ref133\/cit133","doi-asserted-by":"publisher","DOI":"10.1016\/j.impact.2017.09.001"},{"key":"ref134\/cit134","doi-asserted-by":"publisher","DOI":"10.1016\/j.partic.2021.11.007"},{"key":"ref135\/cit135","doi-asserted-by":"publisher","DOI":"10.1038\/s41565-018-0246-4"},{"key":"ref136\/cit136","doi-asserted-by":"publisher","DOI":"10.1002\/wnan.1656"},{"key":"ref137\/cit137","doi-asserted-by":"publisher","DOI":"10.3389\/fpubh.2018.00261"},{"key":"ref138\/cit138","doi-asserted-by":"publisher","DOI":"10.1002\/jin2.34"},{"key":"ref139\/cit139","doi-asserted-by":"publisher","DOI":"10.1002\/etc.4315"},{"key":"ref140\/cit140","doi-asserted-by":"publisher","DOI":"10.1016\/j.yrtph.2020.104662"},{"key":"ref141\/cit141","doi-asserted-by":"publisher","DOI":"10.1080\/17435390.2018.1506060"},{"key":"ref142\/cit142","doi-asserted-by":"publisher","DOI":"10.1016\/j.comtox.2016.07.001"},{"key":"ref143\/cit143","doi-asserted-by":"publisher","DOI":"10.1016\/j.impact.2019.100178"},{"key":"ref144\/cit144","doi-asserted-by":"publisher","DOI":"10.1186\/s12989-016-0123-y"},{"key":"ref145\/cit145","doi-asserted-by":"publisher","DOI":"10.1016\/j.nantod.2021.101242"},{"key":"ref146\/cit146","doi-asserted-by":"publisher","DOI":"10.1080\/17435390.2018.1529835"},{"key":"ref147\/cit147","doi-asserted-by":"publisher","DOI":"10.1016\/j.chemosphere.2018.05.019"},{"key":"ref148\/cit148","doi-asserted-by":"publisher","DOI":"10.1186\/s12989-016-0125-9"},{"key":"ref149\/cit149","doi-asserted-by":"publisher","DOI":"10.1021\/acs.est.5b01837"},{"key":"ref150\/cit150","doi-asserted-by":"publisher","DOI":"10.1080\/17435390.2018.1446559"},{"key":"ref151\/cit151","doi-asserted-by":"publisher","DOI":"10.1208\/s12248-012-9339-4"},{"key":"ref152\/cit152","doi-asserted-by":"publisher","DOI":"10.2217\/nnm-2017-0039"},{"key":"ref153\/cit153","doi-asserted-by":"publisher","DOI":"10.3390\/antiox9030211"},{"key":"ref154\/cit154","doi-asserted-by":"publisher","DOI":"10.3390\/ijms18010120"},{"key":"ref155\/cit155","doi-asserted-by":"publisher","DOI":"10.3390\/nano10061229"},{"key":"ref156\/cit156","doi-asserted-by":"publisher","DOI":"10.1007\/s00204-019-02551-1"},{"key":"ref157\/cit157","doi-asserted-by":"publisher","DOI":"10.1093\/toxsci\/kfu199"},{"key":"ref158\/cit158","doi-asserted-by":"publisher","DOI":"10.1016\/j.csbj.2020.02.014"},{"key":"ref159\/cit159","doi-asserted-by":"publisher","DOI":"10.1039\/C8NR02393J"},{"key":"ref160\/cit160","doi-asserted-by":"publisher","DOI":"10.1517\/17425247.2011.554818"},{"key":"ref161\/cit161","doi-asserted-by":"publisher","DOI":"10.1016\/j.tox.2005.07.023"},{"key":"ref162\/cit162","doi-asserted-by":"publisher","DOI":"10.1016\/j.nantod.2015.06.006"},{"key":"ref163\/cit163","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2016.01.020"},{"key":"ref164\/cit164","doi-asserted-by":"publisher","DOI":"10.1038\/s41578-018-0038-3"},{"key":"ref165\/cit165","doi-asserted-by":"publisher","DOI":"10.1038\/nbt1340"},{"key":"ref166\/cit166","doi-asserted-by":"publisher","DOI":"10.1186\/s11671-015-0922-3"},{"key":"ref167\/cit167","doi-asserted-by":"publisher","DOI":"10.1002\/adtp.201900124"},{"key":"ref168\/cit168","doi-asserted-by":"publisher","DOI":"10.1002\/adma.201805740"},{"key":"ref169\/cit169","doi-asserted-by":"publisher","DOI":"10.1021\/acs.bioconjchem.9b00348"},{"key":"ref170\/cit170","doi-asserted-by":"publisher","DOI":"10.2147\/IJN.S129300"},{"key":"ref171\/cit171","doi-asserted-by":"publisher","DOI":"10.1021\/nn3004845"},{"key":"ref172\/cit172","doi-asserted-by":"publisher","DOI":"10.3389\/fbioe.2019.00414"},{"key":"ref173\/cit173","doi-asserted-by":"publisher","DOI":"10.3389\/fbioe.2020.00166"},{"key":"ref174\/cit174","doi-asserted-by":"publisher","DOI":"10.1021\/nn406018q"},{"key":"ref175\/cit175","doi-asserted-by":"publisher","DOI":"10.1039\/C6NR03898K"},{"key":"ref176\/cit176","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-020-18237-7"},{"key":"ref177\/cit177","doi-asserted-by":"publisher","DOI":"10.1039\/C7NR03042H"},{"key":"ref178\/cit178","doi-asserted-by":"publisher","DOI":"10.1039\/C5NR09158F"},{"key":"ref179\/cit179","doi-asserted-by":"publisher","DOI":"10.1007\/s13346-020-00745-0"},{"key":"ref180\/cit180","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0608582104"},{"key":"ref181\/cit181","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0805135105"},{"key":"ref182\/cit182","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.6b10967"},{"key":"ref183\/cit183","doi-asserted-by":"publisher","DOI":"10.1039\/C6BM00921B"},{"key":"ref184\/cit184","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbapap.2013.01.029"},{"key":"ref185\/cit185","doi-asserted-by":"publisher","DOI":"10.1038\/s41573-020-0090-8"},{"key":"ref186\/cit186","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2020.03.008"},{"key":"ref187\/cit187","doi-asserted-by":"publisher","DOI":"10.1021\/ja107583h"},{"key":"ref188\/cit188","doi-asserted-by":"publisher","DOI":"10.2217\/nnm-2017-0238"},{"key":"ref189\/cit189","doi-asserted-by":"publisher","DOI":"10.1021\/nl202940k"},{"key":"ref190\/cit190","doi-asserted-by":"publisher","DOI":"10.1021\/nl500277c"},{"key":"ref191\/cit191","doi-asserted-by":"publisher","DOI":"10.1039\/C7NR06970G"},{"key":"ref192\/cit192","doi-asserted-by":"publisher","DOI":"10.1007\/s00204-015-1458-0"},{"key":"ref193\/cit193","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.9b03824"},{"key":"ref194\/cit194","doi-asserted-by":"publisher","DOI":"10.1021\/nn405830g"},{"key":"ref195\/cit195","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jproteome.7b00467"},{"key":"ref196\/cit196","doi-asserted-by":"publisher","DOI":"10.1039\/C8EN01054D"},{"key":"ref197\/cit197","doi-asserted-by":"publisher","DOI":"10.1002\/anie.200700465"},{"key":"ref198\/cit198","doi-asserted-by":"publisher","DOI":"10.3389\/fbioe.2020.599454"},{"key":"ref199\/cit199","doi-asserted-by":"publisher","DOI":"10.1016\/j.taap.2015.12.022"},{"key":"ref200\/cit200","doi-asserted-by":"publisher","DOI":"10.1016\/j.impact.2020.100207"},{"key":"ref201\/cit201","doi-asserted-by":"publisher","DOI":"10.1039\/C7EN00466D"},{"key":"ref202\/cit202","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.9b02774"},{"key":"ref203\/cit203","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.6b00261"},{"key":"ref204\/cit204","doi-asserted-by":"publisher","DOI":"10.1021\/la401192x"},{"key":"ref205\/cit205","doi-asserted-by":"publisher","DOI":"10.1038\/204701b0"},{"key":"ref206\/cit206","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V55.1.156.156"},{"key":"ref207\/cit207","doi-asserted-by":"publisher","DOI":"10.1039\/D0RA05241H"},{"key":"ref208\/cit208","doi-asserted-by":"publisher","DOI":"10.1021\/nn3035155"},{"key":"ref209\/cit209","doi-asserted-by":"publisher","DOI":"10.1080\/00268976.2018.1467056"},{"key":"ref210\/cit210","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.7b08008"},{"key":"ref211\/cit211","doi-asserted-by":"publisher","DOI":"10.1016\/j.colsurfb.2017.02.037"},{"key":"ref212\/cit212","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbamem.2015.11.012"},{"key":"ref213\/cit213","doi-asserted-by":"publisher","DOI":"10.1039\/C7NR00078B"},{"key":"ref214\/cit214","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-12-815341-3.00002-X"},{"key":"ref215\/cit215","doi-asserted-by":"publisher","DOI":"10.1021\/nn901657w"},{"key":"ref216\/cit216","doi-asserted-by":"publisher","DOI":"10.1002\/anbr.202000082"},{"key":"ref217\/cit217","doi-asserted-by":"publisher","DOI":"10.1080\/2162402X.2020.1738813"},{"key":"ref218\/cit218","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.201902634"},{"key":"ref219\/cit219","doi-asserted-by":"publisher","DOI":"10.1038\/aps.2017.34"},{"key":"ref220\/cit220","doi-asserted-by":"publisher","DOI":"10.1208\/s12249-019-1325-z"},{"key":"ref221\/cit221","doi-asserted-by":"publisher","DOI":"10.1080\/1061186X.2017.1400552"},{"key":"ref222\/cit222","doi-asserted-by":"publisher","DOI":"10.1038\/nmat4718"},{"key":"ref223\/cit223","doi-asserted-by":"publisher","DOI":"10.1021\/ar2003336"},{"key":"ref224\/cit224","doi-asserted-by":"publisher","DOI":"10.1016\/j.bcp.2018.12.003"},{"key":"ref225\/cit225","doi-asserted-by":"publisher","DOI":"10.3390\/cells8101209"},{"key":"ref226\/cit226","doi-asserted-by":"publisher","DOI":"10.2217\/nnm.13.49"},{"key":"ref227\/cit227","doi-asserted-by":"publisher","DOI":"10.1002\/ajh.26132"},{"key":"ref228\/cit228","doi-asserted-by":"publisher","DOI":"10.1111\/jth.15348"},{"key":"ref229\/cit229","doi-asserted-by":"publisher","DOI":"10.1007\/s12195-020-00622-3"},{"key":"ref230\/cit230","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2020.12.019"},{"key":"ref231\/cit231","doi-asserted-by":"publisher","DOI":"10.1016\/j.addr.2020.02.005"},{"key":"ref232\/cit232","doi-asserted-by":"publisher","DOI":"10.1016\/j.addr.2020.05.011"},{"key":"ref233\/cit233","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2018.11.093"},{"key":"ref234\/cit234","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-019-41643-x"},{"key":"ref235\/cit235","doi-asserted-by":"publisher","DOI":"10.1002\/advs.201900133"},{"key":"ref236\/cit236","doi-asserted-by":"publisher","DOI":"10.1186\/1477-3155-12-5"},{"key":"ref237\/cit237","doi-asserted-by":"publisher","DOI":"10.1053\/j.seminhematol.2005.04.006"},{"key":"ref238\/cit238","doi-asserted-by":"publisher","DOI":"10.1111\/bjh.13183"},{"key":"ref239\/cit239","doi-asserted-by":"publisher","DOI":"10.3324\/haematol.2009.013672"},{"key":"ref240\/cit240","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2017-03-745349"},{"key":"ref241\/cit241","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0199911"},{"key":"ref242\/cit242","doi-asserted-by":"publisher","DOI":"10.3389\/fphys.2018.00041"},{"key":"ref243\/cit243","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2016-10-746479"},{"key":"ref244\/cit244","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-fluid-010814-014513"},{"key":"ref245\/cit245","doi-asserted-by":"publisher","DOI":"10.1021\/nn103077k"},{"key":"ref246\/cit246","doi-asserted-by":"publisher","DOI":"10.1039\/C4NR01857E"},{"key":"ref247\/cit247","doi-asserted-by":"publisher","DOI":"10.4155\/tde-2017-0057"},{"key":"ref248\/cit248","doi-asserted-by":"publisher","DOI":"10.1002\/btm2.10173"},{"key":"ref249\/cit249","doi-asserted-by":"publisher","DOI":"10.1159\/000172777"},{"key":"ref250\/cit250","doi-asserted-by":"publisher","DOI":"10.1038\/ki.1977.107"},{"key":"ref251\/cit251","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9440(10)65006-7"},{"key":"ref252\/cit252","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2013.09.013"},{"key":"ref253\/cit253","doi-asserted-by":"publisher","DOI":"10.3390\/ijms18061249"},{"key":"ref254\/cit254","doi-asserted-by":"publisher","DOI":"10.1021\/nl900031y"},{"key":"ref255\/cit255","doi-asserted-by":"publisher","DOI":"10.2217\/nnm-2018-0040"},{"key":"ref256\/cit256","doi-asserted-by":"publisher","DOI":"10.1016\/j.toxlet.2011.11.006"},{"key":"ref257\/cit257","doi-asserted-by":"publisher","DOI":"10.1007\/s11051-016-3595-7"},{"key":"ref258\/cit258","doi-asserted-by":"publisher","DOI":"10.1016\/0005-2736(92)90136-A"},{"key":"ref259\/cit259","doi-asserted-by":"publisher","DOI":"10.1016\/j.addr.2016.01.007"},{"key":"ref260\/cit260","doi-asserted-by":"publisher","DOI":"10.1039\/C8NR01521J"},{"key":"ref261\/cit261","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2019.01998"},{"key":"ref262\/cit262","doi-asserted-by":"publisher","DOI":"10.1016\/j.jare.2017.10.008"},{"key":"ref263\/cit263","doi-asserted-by":"publisher","DOI":"10.1080\/17435390.2018.1451567"},{"key":"ref264\/cit264","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2017.00606"},{"key":"ref265\/cit265","doi-asserted-by":"publisher","DOI":"10.1016\/j.nantod.2020.100972"},{"key":"ref266\/cit266","doi-asserted-by":"publisher","DOI":"10.1186\/s12989-020-00344-4"},{"key":"ref267\/cit267","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-018-22556-7"},{"key":"ref268\/cit268","doi-asserted-by":"publisher","DOI":"10.1166\/jbn.2020.2921"},{"key":"ref269\/cit269","doi-asserted-by":"publisher","DOI":"10.1186\/1743-8977-4-10"},{"key":"ref270\/cit270","doi-asserted-by":"publisher","DOI":"10.1016\/j.taap.2008.12.023"},{"key":"ref271\/cit271","doi-asserted-by":"publisher","DOI":"10.1016\/j.taap.2010.02.013"},{"key":"ref272\/cit272","doi-asserted-by":"publisher","DOI":"10.1007\/s00441-004-0884-8"},{"key":"ref273\/cit273","doi-asserted-by":"publisher","DOI":"10.1016\/j.taap.2009.09.015"},{"key":"ref274\/cit274","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0905487106"},{"key":"ref275\/cit275","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2009.11.079"},{"key":"ref276\/cit276","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.5b00042"},{"key":"ref277\/cit277","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2011.02.031"},{"key":"ref278\/cit278","doi-asserted-by":"publisher","DOI":"10.1021\/nn800511k"},{"key":"ref279\/cit279","doi-asserted-by":"publisher","DOI":"10.1016\/j.nano.2008.11.002"},{"key":"ref280\/cit280","doi-asserted-by":"publisher","DOI":"10.1186\/s12989-015-0102-8"},{"key":"ref281\/cit281","doi-asserted-by":"publisher","DOI":"10.1039\/C3TB21634A"},{"key":"ref282\/cit282","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2020.00222"},{"key":"ref283\/cit283","doi-asserted-by":"publisher","DOI":"10.1038\/s41565-018-0273-1"},{"key":"ref284\/cit284","doi-asserted-by":"publisher","DOI":"10.2500\/aap.2019.40.4274"},{"key":"ref285\/cit285","doi-asserted-by":"publisher","DOI":"10.1016\/j.addr.2011.06.002"},{"key":"ref286\/cit286","doi-asserted-by":"publisher","DOI":"10.1038\/nnano.2016.269"},{"key":"ref287\/cit287","doi-asserted-by":"publisher","DOI":"10.1124\/jpet.119.258012"},{"key":"ref288\/cit288","doi-asserted-by":"publisher","DOI":"10.1016\/j.molimm.2014.06.038"},{"key":"ref289\/cit289","doi-asserted-by":"publisher","DOI":"10.1016\/j.addr.2011.06.017"},{"key":"ref290\/cit290","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2020.603039"},{"key":"ref291\/cit291","doi-asserted-by":"publisher","DOI":"10.1016\/j.drudis.2017.11.006"},{"key":"ref292\/cit292","doi-asserted-by":"publisher","DOI":"10.1186\/s12989-014-0064-2"},{"key":"ref293\/cit293","doi-asserted-by":"publisher","DOI":"10.2147\/IJN.S168808"},{"key":"ref294\/cit294","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2019.00133"},{"key":"ref295\/cit295","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.1502011"},{"key":"ref296\/cit296","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M805547200"},{"key":"ref297\/cit297","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.95.20.11509"},{"key":"ref298\/cit298","doi-asserted-by":"publisher","DOI":"10.1016\/j.smim.2017.09.003"},{"key":"ref299\/cit299","doi-asserted-by":"publisher","DOI":"10.1021\/ja2084338"},{"key":"ref300\/cit300","doi-asserted-by":"publisher","DOI":"10.1517\/17425247.2012.720969"},{"issue":"1","key":"ref301\/cit301","first-page":"37","volume":"10","author":"Sroda K.","year":"2005","journal-title":"Cell. Mol. Biol. Lett."},{"key":"ref302\/cit302","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2015.10.034"},{"key":"ref303\/cit303","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-7643-8679-5_9"},{"key":"ref304\/cit304","doi-asserted-by":"publisher","DOI":"10.1159\/000233512"},{"key":"ref305\/cit305","doi-asserted-by":"publisher","DOI":"10.1111\/cea.13874"},{"key":"ref306\/cit306","doi-asserted-by":"publisher","DOI":"10.1111\/all.14725"},{"key":"ref307\/cit307","doi-asserted-by":"publisher","DOI":"10.1111\/all.14774"},{"key":"ref308\/cit308","doi-asserted-by":"publisher","DOI":"10.3389\/fbioe.2022.882363"},{"key":"ref309\/cit309","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2006.01.005"},{"key":"ref310\/cit310","doi-asserted-by":"publisher","DOI":"10.1016\/j.ymthe.2005.09.014"},{"key":"ref311\/cit311","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2020.04.011"},{"key":"ref312\/cit312","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.1c05922"},{"key":"ref313\/cit313","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-08-101750-0.00013-1"},{"key":"ref314\/cit314","doi-asserted-by":"publisher","DOI":"10.1016\/j.eurpolymj.2016.10.041"},{"key":"ref315\/cit315","doi-asserted-by":"publisher","DOI":"10.1002\/adtp.201900170"},{"key":"ref316\/cit316","doi-asserted-by":"publisher","DOI":"10.1002\/adhm.202000529"},{"key":"ref317\/cit317","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejpb.2022.01.004"},{"key":"ref318\/cit318","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-019-11718-4"},{"key":"ref319\/cit319","doi-asserted-by":"publisher","DOI":"10.1016\/j.nucmedbio.2020.04.001"},{"key":"ref320\/cit320","doi-asserted-by":"publisher","DOI":"10.1038\/s41392-021-00631-2"},{"key":"ref321\/cit321","doi-asserted-by":"publisher","DOI":"10.1002\/adma.202001808"},{"key":"ref322\/cit322","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2018.08.016"},{"key":"ref323\/cit323","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-bioeng-121219-024239"},{"key":"ref324\/cit324","doi-asserted-by":"publisher","DOI":"10.1039\/D1NH00291K"},{"key":"ref325\/cit325","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-018-05079-7"},{"key":"ref326\/cit326","doi-asserted-by":"publisher","DOI":"10.7150\/thno.37204"},{"key":"ref327\/cit327","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2016.04.028"},{"key":"ref328\/cit328","doi-asserted-by":"publisher","DOI":"10.1038\/nnano.2011.166"},{"key":"ref329\/cit329","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1318415110"},{"key":"ref330\/cit330","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2014.03.057"},{"key":"ref331\/cit331","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.5b01324"},{"key":"ref332\/cit332","doi-asserted-by":"publisher","DOI":"10.1038\/nature10144"},{"key":"ref333\/cit333","doi-asserted-by":"publisher","DOI":"10.1016\/j.addr.2015.01.002"},{"key":"ref334\/cit334","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-12-4561"},{"key":"ref335\/cit335","doi-asserted-by":"publisher","DOI":"10.1038\/natrevmats.2016.14"},{"key":"ref336\/cit336","doi-asserted-by":"publisher","DOI":"10.1038\/natrevmats.2016.73"},{"key":"ref337\/cit337","doi-asserted-by":"publisher","DOI":"10.1126\/sciadv.aay9249"},{"key":"ref338\/cit338","doi-asserted-by":"publisher","DOI":"10.1002\/nano.202200043"},{"key":"ref339\/cit339","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.1c04510"},{"key":"ref340\/cit340","doi-asserted-by":"publisher","DOI":"10.1007\/s13346-013-0176-5"},{"key":"ref341\/cit341","doi-asserted-by":"publisher","DOI":"10.1021\/acsomega.8b03227"},{"key":"ref342\/cit342","doi-asserted-by":"publisher","DOI":"10.1021\/ja309812z"},{"key":"ref343\/cit343","doi-asserted-by":"publisher","DOI":"10.1007\/s11051-011-0375-2"},{"key":"ref344\/cit344","doi-asserted-by":"publisher","DOI":"10.1038\/nnano.2012.237"},{"key":"ref345\/cit345","doi-asserted-by":"publisher","DOI":"10.2147\/IJN.S29334"},{"key":"ref346\/cit346","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.5b03521"},{"key":"ref347\/cit347","doi-asserted-by":"publisher","DOI":"10.1186\/s12645-014-0007-5"},{"key":"ref348\/cit348","doi-asserted-by":"publisher","DOI":"10.1007\/s11095-010-0360-y"},{"key":"ref349\/cit349","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2012.05.014"},{"key":"ref350\/cit350","doi-asserted-by":"publisher","DOI":"10.1021\/acs.nanolett.9b03211"},{"key":"ref351\/cit351","doi-asserted-by":"publisher","DOI":"10.7150\/thno.37198"},{"key":"ref352\/cit352","doi-asserted-by":"publisher","DOI":"10.1152\/physrev.00001.2003"},{"key":"ref353\/cit353","doi-asserted-by":"publisher","DOI":"10.1007\/s12274-016-1220-9"},{"key":"ref354\/cit354","doi-asserted-by":"publisher","DOI":"10.1186\/s12943-019-1089-9"},{"key":"ref355\/cit355","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2017.00952"},{"key":"ref356\/cit356","doi-asserted-by":"publisher","DOI":"10.1038\/427695a"},{"key":"ref357\/cit357","doi-asserted-by":"publisher","DOI":"10.1038\/nrc1456"},{"key":"ref358\/cit358","doi-asserted-by":"publisher","DOI":"10.1016\/j.neo.2014.07.003"},{"key":"ref359\/cit359","doi-asserted-by":"publisher","DOI":"10.2147\/HP.S93413"},{"key":"ref360\/cit360","doi-asserted-by":"publisher","DOI":"10.1038\/onc.2012.578"},{"key":"ref361\/cit361","doi-asserted-by":"publisher","DOI":"10.1007\/s10555-007-9055-1"},{"key":"ref362\/cit362","doi-asserted-by":"publisher","DOI":"10.1038\/oncsis.2015.50"},{"key":"ref363\/cit363","doi-asserted-by":"publisher","DOI":"10.2147\/IJN.S140462"},{"key":"ref364\/cit364","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-16-0895"},{"key":"ref365\/cit365","doi-asserted-by":"publisher","DOI":"10.1038\/nrc3183"},{"key":"ref366\/cit366","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2012-02-408419"},{"key":"ref367\/cit367","doi-asserted-by":"publisher","DOI":"10.2147\/IJN.S210116"},{"key":"ref368\/cit368","doi-asserted-by":"publisher","DOI":"10.1039\/C8CS00304A"},{"key":"ref369\/cit369","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.6b02776"},{"key":"ref370\/cit370","doi-asserted-by":"publisher","DOI":"10.1016\/j.nano.2015.12.382"},{"key":"ref371\/cit371","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-13-3494"},{"key":"ref372\/cit372","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.6b06245"},{"key":"ref373\/cit373","doi-asserted-by":"publisher","DOI":"10.1016\/j.trecan.2020.02.022"},{"key":"ref374\/cit374","doi-asserted-by":"publisher","DOI":"10.3390\/ijms21093125"},{"key":"ref375\/cit375","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.57243"},{"key":"ref376\/cit376","doi-asserted-by":"publisher","DOI":"10.1126\/sciadv.aay1601"},{"key":"ref377\/cit377","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccr.2012.01.007"},{"key":"ref378\/cit378","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2016.06.048"},{"key":"ref379\/cit379","doi-asserted-by":"publisher","DOI":"10.7150\/thno.49577"},{"key":"ref380\/cit380","doi-asserted-by":"publisher","DOI":"10.1016\/j.addr.2017.07.007"},{"key":"ref381\/cit381","doi-asserted-by":"publisher","DOI":"10.1021\/acsbiomaterials.0c00743"},{"key":"ref382\/cit382","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2017.12.015"},{"key":"ref383\/cit383","doi-asserted-by":"publisher","DOI":"10.1016\/j.addr.2022.114303"},{"key":"ref384\/cit384","doi-asserted-by":"publisher","DOI":"10.1021\/cr200472g"},{"key":"ref385\/cit385","doi-asserted-by":"publisher","DOI":"10.1016\/j.mattod.2020.02.001"},{"key":"ref386\/cit386","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2016.05.044"},{"key":"ref387\/cit387","doi-asserted-by":"publisher","DOI":"10.1016\/j.addr.2021.113847"},{"key":"ref388\/cit388","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuropharm.2016.02.014"},{"key":"ref389\/cit389","doi-asserted-by":"publisher","DOI":"10.1021\/acs.langmuir.8b03779"},{"key":"ref390\/cit390","doi-asserted-by":"publisher","DOI":"10.1007\/s13534-017-0016-5"},{"key":"ref391\/cit391","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcis.2018.10.108"},{"key":"ref392\/cit392","doi-asserted-by":"publisher","DOI":"10.1021\/acsomega.8b03169"},{"key":"ref393\/cit393","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijbiomac.2022.03.006"},{"key":"ref394\/cit394","doi-asserted-by":"publisher","DOI":"10.1039\/C8NR04506B"},{"key":"ref395\/cit395","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-019-10112-4"},{"key":"ref396\/cit396","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2014.06.038"},{"key":"ref397\/cit397","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-018-25878-8"},{"key":"ref398\/cit398","doi-asserted-by":"publisher","DOI":"10.1039\/C7PY01603D"},{"key":"ref399\/cit399","doi-asserted-by":"publisher","DOI":"10.1038\/s41392-020-00342-0"},{"key":"ref400\/cit400","doi-asserted-by":"publisher","DOI":"10.1021\/acs.langmuir.6b04304"},{"key":"ref401\/cit401","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-020-75125-2"},{"key":"ref402\/cit402","doi-asserted-by":"publisher","DOI":"10.2147\/IJN.S226186"},{"key":"ref403\/cit403","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.0c06872"},{"key":"ref404\/cit404","doi-asserted-by":"publisher","DOI":"10.1038\/nbt1292"},{"key":"ref405\/cit405","doi-asserted-by":"publisher","DOI":"10.1016\/j.mito.2012.09.001"},{"key":"ref406\/cit406","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2020.02.001"},{"key":"ref407\/cit407","doi-asserted-by":"publisher","DOI":"10.1208\/s12249-020-01873-z"},{"key":"ref408\/cit408","doi-asserted-by":"publisher","DOI":"10.1042\/bj3560549"},{"key":"ref409\/cit409","doi-asserted-by":"publisher","DOI":"10.1016\/j.cej.2019.03.272"},{"key":"ref410\/cit410","doi-asserted-by":"publisher","DOI":"10.1039\/c4nr01234h"},{"key":"ref411\/cit411","doi-asserted-by":"publisher","DOI":"10.1002\/smll.201100001"},{"key":"ref412\/cit412","doi-asserted-by":"publisher","DOI":"10.1016\/j.bpj.2017.09.035"},{"key":"ref413\/cit413","doi-asserted-by":"publisher","DOI":"10.3390\/nano10091816"},{"key":"ref414\/cit414","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2010.01.036"},{"key":"ref415\/cit415","doi-asserted-by":"publisher","DOI":"10.1039\/C6CS00636A"},{"key":"ref416\/cit416","doi-asserted-by":"publisher","DOI":"10.1016\/j.addr.2019.04.008"},{"key":"ref417\/cit417","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2018.09.097"},{"key":"ref418\/cit418","doi-asserted-by":"publisher","DOI":"10.1021\/nn301282m"},{"key":"ref419\/cit419","doi-asserted-by":"publisher","DOI":"10.1038\/nnano.2006.209"},{"key":"ref420\/cit420","doi-asserted-by":"publisher","DOI":"10.1021\/ar300031y"},{"key":"ref421\/cit421","doi-asserted-by":"publisher","DOI":"10.1007\/s00018-009-0053-z"},{"key":"ref422\/cit422","doi-asserted-by":"publisher","DOI":"10.1186\/s11671-018-2728-6"},{"key":"ref423\/cit423","doi-asserted-by":"publisher","DOI":"10.1016\/j.it.2017.03.006"},{"key":"ref424\/cit424","doi-asserted-by":"publisher","DOI":"10.1038\/nri3244"},{"key":"ref425\/cit425","doi-asserted-by":"publisher","DOI":"10.1038\/nri2448"},{"key":"ref426\/cit426","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-12-417028-5.00006-5"},{"key":"ref427\/cit427","doi-asserted-by":"publisher","DOI":"10.1038\/nnano.2007.223"},{"key":"ref428\/cit428","doi-asserted-by":"publisher","DOI":"10.1021\/nn100262h"},{"key":"ref429\/cit429","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.biochem.69.1.699"},{"key":"ref430\/cit430","doi-asserted-by":"publisher","DOI":"10.1038\/nature01451"},{"key":"ref431\/cit431","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2012.05.047"},{"key":"ref432\/cit432","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pbio.0040262"},{"key":"ref433\/cit433","doi-asserted-by":"publisher","DOI":"10.1016\/j.cub.2011.05.048"},{"key":"ref434\/cit434","doi-asserted-by":"publisher","DOI":"10.1038\/nrm.2017.132"},{"key":"ref435\/cit435","doi-asserted-by":"publisher","DOI":"10.1038\/nrm3151"},{"key":"ref436\/cit436","doi-asserted-by":"publisher","DOI":"10.15252\/embj.201694613"},{"key":"ref437\/cit437","doi-asserted-by":"publisher","DOI":"10.32607\/20758251-2013-5-3-62-73"},{"key":"ref438\/cit438","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2020.07.032"},{"key":"ref439\/cit439","doi-asserted-by":"publisher","DOI":"10.1016\/j.addr.2012.09.041"},{"key":"ref440\/cit440","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.03970"},{"key":"ref441\/cit441","doi-asserted-by":"publisher","DOI":"10.1039\/D1NR01547H"},{"key":"ref442\/cit442","doi-asserted-by":"publisher","DOI":"10.1016\/S0360-3016(97)00587-7"},{"key":"ref443\/cit443","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.biochem.67.1.199"},{"key":"ref444\/cit444","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0854.2002.30501.x"},{"key":"ref445\/cit445","doi-asserted-by":"publisher","DOI":"10.1111\/jcmm.13110"},{"key":"ref446\/cit446","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.201009093"},{"key":"ref447\/cit447","doi-asserted-by":"publisher","DOI":"10.1016\/j.tcb.2015.10.010"},{"key":"ref448\/cit448","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.201003086"},{"key":"ref449\/cit449","doi-asserted-by":"publisher","DOI":"10.1016\/j.ceb.2020.02.001"},{"key":"ref450\/cit450","doi-asserted-by":"publisher","DOI":"10.1152\/physiologyonline.2001.16.2.61"},{"key":"ref451\/cit451","doi-asserted-by":"publisher","DOI":"10.1091\/mbc.e03-01-0050"},{"key":"ref452\/cit452","doi-asserted-by":"publisher","DOI":"10.1002\/iub.485"},{"key":"ref453\/cit453","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-17-0604"},{"key":"ref454\/cit454","doi-asserted-by":"publisher","DOI":"10.1016\/j.addr.2007.08.044"},{"key":"ref455\/cit455","doi-asserted-by":"publisher","DOI":"10.1038\/cr.2010.19"},{"key":"ref456\/cit456","doi-asserted-by":"publisher","DOI":"10.1039\/D0CS01127D"},{"key":"ref457\/cit457","doi-asserted-by":"publisher","DOI":"10.1016\/j.ceb.2011.03.007"},{"key":"ref458\/cit458","doi-asserted-by":"publisher","DOI":"10.3390\/pharmaceutics12040371"},{"key":"ref459\/cit459","doi-asserted-by":"publisher","DOI":"10.1016\/j.addr.2012.09.020"},{"key":"ref460\/cit460","doi-asserted-by":"publisher","DOI":"10.1021\/acs.nanolett.7b03021"},{"key":"ref461\/cit461","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejpb.2012.10.011"},{"key":"ref462\/cit462","doi-asserted-by":"publisher","DOI":"10.3762\/bjnano.6.16"},{"key":"ref463\/cit463","doi-asserted-by":"publisher","DOI":"10.1098\/rstb.2018.0157"},{"key":"ref464\/cit464","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0854.2009.00878.x"},{"key":"ref465\/cit465","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0801763105"},{"key":"ref466\/cit466","doi-asserted-by":"publisher","DOI":"10.1242\/jcs.03238"},{"key":"ref467\/cit467","doi-asserted-by":"publisher","DOI":"10.1002\/smll.201801451"},{"key":"ref468\/cit468","doi-asserted-by":"publisher","DOI":"10.1038\/nnano.2008.30"},{"key":"ref469\/cit469","doi-asserted-by":"publisher","DOI":"10.1186\/1477-3155-8-33"},{"key":"ref470\/cit470","doi-asserted-by":"publisher","DOI":"10.1002\/smll.200900005"},{"key":"ref471\/cit471","doi-asserted-by":"publisher","DOI":"10.1021\/nl052396o"},{"key":"ref472\/cit472","doi-asserted-by":"publisher","DOI":"10.2217\/nnm.16.5"},{"key":"ref473\/cit473","doi-asserted-by":"publisher","DOI":"10.1103\/PhysRevLett.105.138101"},{"key":"ref474\/cit474","doi-asserted-by":"publisher","DOI":"10.1016\/j.nano.2012.05.015"},{"key":"ref475\/cit475","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0503879102"},{"key":"ref476\/cit476","doi-asserted-by":"publisher","DOI":"10.1039\/c3nr33280b"},{"key":"ref477\/cit477","doi-asserted-by":"publisher","DOI":"10.1186\/1743-8977-10-56"},{"key":"ref478\/cit478","doi-asserted-by":"publisher","DOI":"10.1021\/nn2007496"},{"key":"ref479\/cit479","doi-asserted-by":"publisher","DOI":"10.1021\/nn103344k"},{"key":"ref480\/cit480","doi-asserted-by":"publisher","DOI":"10.1021\/nl403949h"},{"key":"ref481\/cit481","doi-asserted-by":"publisher","DOI":"10.1021\/acsmacrolett.6b00419"},{"key":"ref482\/cit482","doi-asserted-by":"publisher","DOI":"10.1016\/j.micromeso.2012.05.040"},{"key":"ref483\/cit483","doi-asserted-by":"publisher","DOI":"10.1021\/nn304439f"},{"key":"ref484\/cit484","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.7b01112"},{"key":"ref485\/cit485","doi-asserted-by":"publisher","DOI":"10.1002\/jat.1486"},{"key":"ref486\/cit486","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.8b05340"},{"key":"ref487\/cit487","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-017-02588-9"},{"key":"ref488\/cit488","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.7b07797"},{"key":"ref489\/cit489","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.5b00147"},{"key":"ref490\/cit490","doi-asserted-by":"publisher","DOI":"10.1038\/nrm1315"},{"key":"ref491\/cit491","doi-asserted-by":"publisher","DOI":"10.14670\/HH-25.99"},{"key":"ref492\/cit492","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2017.06.007"},{"key":"ref493\/cit493","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms15646"},{"key":"ref494\/cit494","doi-asserted-by":"publisher","DOI":"10.1038\/nrm2755"},{"key":"ref495\/cit495","doi-asserted-by":"publisher","DOI":"10.1039\/C7NR00532F"},{"key":"ref496\/cit496","doi-asserted-by":"publisher","DOI":"10.1007\/s11064-018-2627-3"},{"key":"ref497\/cit497","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-physiol-012110-142317"},{"key":"ref498\/cit498","doi-asserted-by":"publisher","DOI":"10.1242\/jcs.066399"},{"key":"ref499\/cit499","doi-asserted-by":"publisher","DOI":"10.1038\/nrm3332"},{"key":"ref500\/cit500","doi-asserted-by":"publisher","DOI":"10.1016\/j.devcel.2017.02.016"},{"key":"ref501\/cit501","doi-asserted-by":"publisher","DOI":"10.1038\/nrm2245"},{"key":"ref502\/cit502","doi-asserted-by":"publisher","DOI":"10.1101\/gad.1599207"},{"key":"ref503\/cit503","doi-asserted-by":"publisher","DOI":"10.2119\/molmed.2017.00077"},{"key":"ref504\/cit504","doi-asserted-by":"publisher","DOI":"10.1080\/15548627.2018.1509171"},{"key":"ref505\/cit505","doi-asserted-by":"publisher","DOI":"10.2147\/IJN.S123596"},{"key":"ref506\/cit506","doi-asserted-by":"publisher","DOI":"10.1021\/nn202155y"},{"key":"ref507\/cit507","doi-asserted-by":"publisher","DOI":"10.1021\/acsabm.0c00640"},{"key":"ref508\/cit508","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-065X.2012.01146.x"},{"key":"ref509\/cit509","doi-asserted-by":"publisher","DOI":"10.1038\/nnano.2015.111"},{"key":"ref510\/cit510","doi-asserted-by":"publisher","DOI":"10.1016\/j.etap.2016.07.003"},{"key":"ref511\/cit511","doi-asserted-by":"publisher","DOI":"10.1016\/j.nantod.2014.04.011"},{"key":"ref512\/cit512","doi-asserted-by":"publisher","DOI":"10.1021\/nn200007z"},{"key":"ref513\/cit513","doi-asserted-by":"publisher","DOI":"10.1021\/acs.bioconjchem.7b00658"},{"key":"ref514\/cit514","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejpb.2018.05.034"},{"key":"ref515\/cit515","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.9b05521"},{"key":"ref516\/cit516","doi-asserted-by":"publisher","DOI":"10.1080\/10715762.2020.1859108"},{"key":"ref517\/cit517","doi-asserted-by":"publisher","DOI":"10.1186\/s11671-020-03344-7"},{"key":"ref518\/cit518","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-pharmtox-032320-110338"},{"key":"ref519\/cit519","doi-asserted-by":"publisher","DOI":"10.1007\/s11095-017-2097-3"},{"key":"ref520\/cit520","doi-asserted-by":"publisher","DOI":"10.1021\/la401556k"},{"key":"ref521\/cit521","doi-asserted-by":"publisher","DOI":"10.1002\/smll.201102595"},{"key":"ref522\/cit522","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2007.03.006"},{"key":"ref523\/cit523","doi-asserted-by":"publisher","DOI":"10.1166\/jnn.2013.7525"},{"key":"ref524\/cit524","doi-asserted-by":"publisher","DOI":"10.1021\/jp9033936"},{"key":"ref525\/cit525","doi-asserted-by":"publisher","DOI":"10.1021\/es1034188"},{"key":"ref526\/cit526","doi-asserted-by":"publisher","DOI":"10.2147\/IJN.S36111"},{"key":"ref527\/cit527","doi-asserted-by":"publisher","DOI":"10.1039\/c0nr00478b"},{"key":"ref528\/cit528","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2011.01.021"},{"key":"ref529\/cit529","doi-asserted-by":"publisher","DOI":"10.1021\/es051043o"},{"key":"ref530\/cit530","doi-asserted-by":"publisher","DOI":"10.1016\/j.colsurfb.2009.08.049"},{"key":"ref531\/cit531","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2014.04.009"},{"key":"ref532\/cit532","doi-asserted-by":"publisher","DOI":"10.1021\/acs.est.0c04097"},{"key":"ref533\/cit533","doi-asserted-by":"publisher","DOI":"10.1016\/j.nano.2013.04.010"},{"key":"ref534\/cit534","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.7b18648"},{"key":"ref535\/cit535","doi-asserted-by":"publisher","DOI":"10.1002\/adma.201704307"},{"key":"ref536\/cit536","doi-asserted-by":"publisher","DOI":"10.3390\/pharmaceutics11100543"},{"key":"ref537\/cit537","doi-asserted-by":"publisher","DOI":"10.2147\/DDDT.S45614"},{"key":"ref538\/cit538","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2016.04.026"},{"key":"ref539\/cit539","doi-asserted-by":"publisher","DOI":"10.1016\/j.nano.2012.09.002"},{"key":"ref540\/cit540","doi-asserted-by":"publisher","DOI":"10.1155\/2013\/123838"},{"key":"ref541\/cit541","doi-asserted-by":"publisher","DOI":"10.1002\/jgm.2669"},{"key":"ref542\/cit542","doi-asserted-by":"publisher","DOI":"10.1016\/j.str.2012.03.025"},{"key":"ref543\/cit543","doi-asserted-by":"publisher","DOI":"10.1021\/nn5008572"},{"key":"ref544\/cit544","doi-asserted-by":"publisher","DOI":"10.1039\/C4NR02535K"},{"key":"ref545\/cit545","doi-asserted-by":"publisher","DOI":"10.1021\/ja211035w"},{"key":"ref546\/cit546","doi-asserted-by":"publisher","DOI":"10.1016\/j.addr.2007.10.008"},{"key":"ref547\/cit547","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.6b07173"},{"key":"ref548\/cit548","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2016.01.057"},{"key":"ref549\/cit549","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2019.01.048"},{"key":"ref550\/cit550","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.7b06870"},{"key":"ref551\/cit551","doi-asserted-by":"publisher","DOI":"10.1039\/C9CC01651A"},{"key":"ref552\/cit552","doi-asserted-by":"publisher","DOI":"10.1002\/adhm.201601289"},{"key":"ref553\/cit553","doi-asserted-by":"publisher","DOI":"10.1021\/nn201624c"},{"key":"ref554\/cit554","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jpcb.6b12182"},{"key":"ref555\/cit555","doi-asserted-by":"publisher","DOI":"10.1002\/smll.201401056"},{"key":"ref556\/cit556","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejps.2009.11.010"},{"key":"ref557\/cit557","doi-asserted-by":"publisher","DOI":"10.3390\/ijms21217941"},{"key":"ref558\/cit558","doi-asserted-by":"publisher","DOI":"10.1038\/s42255-020-0172-2"},{"key":"ref559\/cit559","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajps.2020.10.002"},{"key":"ref560\/cit560","doi-asserted-by":"publisher","DOI":"10.1038\/nchembio.1712"},{"key":"ref561\/cit561","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2011.02.013"},{"key":"ref562\/cit562","doi-asserted-by":"publisher","DOI":"10.1039\/C4SC01963F"},{"key":"ref563\/cit563","doi-asserted-by":"publisher","DOI":"10.1097\/CAD.0b013e32836442c6"},{"key":"ref564\/cit564","doi-asserted-by":"publisher","DOI":"10.3390\/cancers12010004"},{"key":"ref565\/cit565","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.C000518200"},{"key":"ref566\/cit566","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M106802200"},{"key":"ref567\/cit567","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/92.13.1042"},{"key":"ref568\/cit568","doi-asserted-by":"publisher","DOI":"10.1016\/j.ab.2017.07.009"},{"key":"ref569\/cit569","doi-asserted-by":"publisher","DOI":"10.1096\/fj.202001693R"},{"key":"ref570\/cit570","doi-asserted-by":"publisher","DOI":"10.1007\/s10689-014-9757-9"},{"key":"ref571\/cit571","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2015.09.022"},{"key":"ref572\/cit572","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2018.00922"},{"key":"ref573\/cit573","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2019.04.034"},{"key":"ref574\/cit574","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmst.2021.01.035"},{"key":"ref575\/cit575","doi-asserted-by":"publisher","DOI":"10.1021\/jp511870e"},{"key":"ref576\/cit576","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.7b01540"},{"key":"ref577\/cit577","doi-asserted-by":"publisher","DOI":"10.1039\/C5NR05139H"},{"key":"ref578\/cit578","doi-asserted-by":"publisher","DOI":"10.1038\/cddis.2016.418"},{"key":"ref579\/cit579","doi-asserted-by":"publisher","DOI":"10.1038\/s41419-021-03614-x"},{"key":"ref580\/cit580","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2021.111708"},{"key":"ref581\/cit581","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2012.03.020"},{"key":"ref582\/cit582","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpharm.2020.120117"},{"key":"ref583\/cit583","doi-asserted-by":"publisher","DOI":"10.3109\/10715761003667554"},{"key":"ref584\/cit584","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-cancerbio-041916-065808"},{"key":"ref585\/cit585","doi-asserted-by":"publisher","DOI":"10.1016\/j.cub.2014.03.034"},{"key":"ref586\/cit586","doi-asserted-by":"publisher","DOI":"10.1093\/jb\/mvs006"},{"key":"ref587\/cit587","doi-asserted-by":"publisher","DOI":"10.1038\/s12276-020-0384-2"},{"key":"ref588\/cit588","doi-asserted-by":"publisher","DOI":"10.1038\/nrc3803"},{"key":"ref589\/cit589","doi-asserted-by":"publisher","DOI":"10.1038\/nrd2803"},{"key":"ref590\/cit590","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-07-5259"},{"issue":"16","key":"ref591\/cit591","first-page":"4261","volume":"54","author":"Safford S. E.","year":"1994","journal-title":"Cancer Res."},{"key":"ref592\/cit592","doi-asserted-by":"publisher","DOI":"10.1016\/0014-5793(94)01368-B"},{"key":"ref593\/cit593","doi-asserted-by":"publisher","DOI":"10.1515\/BC.2006.049"},{"issue":"1","key":"ref594\/cit594","first-page":"39","volume":"26","author":"Mart\u00ednez-S\u00e1nchez G.","year":"2007","journal-title":"J. Exp. Clin. Cancer Res."},{"key":"ref595\/cit595","doi-asserted-by":"publisher","DOI":"10.1093\/carcin\/bgh204"},{"key":"ref596\/cit596","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-06-3137"},{"key":"ref597\/cit597","doi-asserted-by":"publisher","DOI":"10.1038\/nrd4002"},{"key":"ref598\/cit598","doi-asserted-by":"publisher","DOI":"10.1126\/science.aaa5004"},{"key":"ref599\/cit599","doi-asserted-by":"publisher","DOI":"10.18632\/oncotarget.9517"},{"key":"ref600\/cit600","doi-asserted-by":"publisher","DOI":"10.3390\/cancers11010112"},{"key":"ref601\/cit601","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcis.2018.04.017"},{"key":"ref602\/cit602","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2012.03.042"},{"key":"ref603\/cit603","doi-asserted-by":"publisher","DOI":"10.1080\/17435390.2017.1293750"},{"key":"ref604\/cit604","doi-asserted-by":"publisher","DOI":"10.1038\/emm.2006.63"},{"key":"ref605\/cit605","doi-asserted-by":"publisher","DOI":"10.1021\/ja210239k"},{"key":"ref606\/cit606","doi-asserted-by":"publisher","DOI":"10.1016\/j.nano.2011.01.014"},{"key":"ref607\/cit607","doi-asserted-by":"publisher","DOI":"10.1039\/c2nr31227a"},{"key":"ref608\/cit608","doi-asserted-by":"publisher","DOI":"10.1038\/am.2013.88"},{"key":"ref609\/cit609","doi-asserted-by":"publisher","DOI":"10.1021\/acs.chemrev.7b00776"},{"key":"ref610\/cit610","doi-asserted-by":"publisher","DOI":"10.1021\/ar400068w"},{"key":"ref611\/cit611","doi-asserted-by":"publisher","DOI":"10.1107\/S2053273316013516"},{"key":"ref612\/cit612","doi-asserted-by":"publisher","DOI":"10.1126\/science.1261412"},{"key":"ref613\/cit613","doi-asserted-by":"publisher","DOI":"10.1016\/j.comptc.2013.07.009"},{"key":"ref614\/cit614","doi-asserted-by":"publisher","DOI":"10.1186\/s12645-019-0057-9"},{"key":"ref615\/cit615","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2020.120537"},{"key":"ref616\/cit616","doi-asserted-by":"publisher","DOI":"10.3390\/cancers11081191"},{"key":"ref617\/cit617","doi-asserted-by":"publisher","DOI":"10.1088\/1361-6528\/aa8d9c"},{"key":"ref618\/cit618","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.8b07635"},{"key":"ref619\/cit619","doi-asserted-by":"publisher","DOI":"10.1039\/C8TB02947D"},{"key":"ref620\/cit620","doi-asserted-by":"publisher","DOI":"10.1021\/acs.chemrev.7b00161"},{"key":"ref621\/cit621","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2015.01.012"},{"key":"ref622\/cit622","doi-asserted-by":"publisher","DOI":"10.1021\/acs.chemrev.0c00977"},{"key":"ref623\/cit623","doi-asserted-by":"publisher","DOI":"10.1021\/acs.est.9b01676"},{"key":"ref624\/cit624","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1819382116"},{"key":"ref625\/cit625","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhazmat.2014.04.054"},{"key":"ref626\/cit626","doi-asserted-by":"publisher","DOI":"10.1021\/acsabm.0c00098"},{"key":"ref627\/cit627","doi-asserted-by":"publisher","DOI":"10.1039\/c2an35072f"},{"key":"ref628\/cit628","doi-asserted-by":"publisher","DOI":"10.1038\/nnano.2007.260"},{"key":"ref629\/cit629","doi-asserted-by":"publisher","DOI":"10.3109\/10715762.2010.532494"},{"key":"ref630\/cit630","doi-asserted-by":"publisher","DOI":"10.1007\/s40820-019-0347-0"},{"key":"ref631\/cit631","doi-asserted-by":"publisher","DOI":"10.1016\/j.redox.2016.10.010"},{"key":"ref632\/cit632","doi-asserted-by":"publisher","DOI":"10.1021\/bi9020378"},{"key":"ref633\/cit633","doi-asserted-by":"publisher","DOI":"10.3892\/or.2018.6535"},{"key":"ref634\/cit634","doi-asserted-by":"publisher","DOI":"10.1016\/j.freeradbiomed.2012.06.030"},{"key":"ref635\/cit635","doi-asserted-by":"publisher","DOI":"10.1186\/s12964-015-0118-6"},{"key":"ref636\/cit636","doi-asserted-by":"publisher","DOI":"10.1016\/j.cclet.2017.05.023"},{"key":"ref637\/cit637","doi-asserted-by":"publisher","DOI":"10.1016\/j.colsurfb.2018.12.041"},{"key":"ref638\/cit638","doi-asserted-by":"publisher","DOI":"10.1155\/2013\/942916"},{"key":"ref639\/cit639","doi-asserted-by":"publisher","DOI":"10.1021\/nn300291r"},{"key":"ref640\/cit640","doi-asserted-by":"publisher","DOI":"10.1002\/adma.201601902"},{"key":"ref641\/cit641","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.9b03457"},{"key":"ref642\/cit642","doi-asserted-by":"publisher","DOI":"10.1002\/advs.201901461"},{"key":"ref643\/cit643","doi-asserted-by":"publisher","DOI":"10.1002\/advs.201902137"},{"key":"ref644\/cit644","doi-asserted-by":"publisher","DOI":"10.7150\/thno.22465"},{"key":"ref645\/cit645","doi-asserted-by":"publisher","DOI":"10.1016\/j.cej.2019.123138"},{"key":"ref646\/cit646","doi-asserted-by":"publisher","DOI":"10.1039\/C9SC00747D"},{"key":"ref647\/cit647","doi-asserted-by":"publisher","DOI":"10.1039\/C9CC07878A"},{"key":"ref648\/cit648","doi-asserted-by":"publisher","DOI":"10.1016\/j.molcata.2013.08.017"},{"key":"ref649\/cit649","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcat.2013.01.025"},{"key":"ref650\/cit650","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhazmat.2017.10.020"},{"key":"ref651\/cit651","doi-asserted-by":"publisher","DOI":"10.1166\/jnn.2020.17432"},{"key":"ref652\/cit652","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.1c12235"},{"key":"ref653\/cit653","doi-asserted-by":"publisher","DOI":"10.1039\/C5AY00895F"},{"key":"ref654\/cit654","doi-asserted-by":"publisher","DOI":"10.1007\/s10311-020-00985-z"},{"key":"ref655\/cit655","doi-asserted-by":"publisher","DOI":"10.1016\/S0041-008X(03)00092-9"},{"key":"ref656\/cit656","doi-asserted-by":"publisher","DOI":"10.1016\/j.toxlet.2009.08.011"},{"key":"ref657\/cit657","doi-asserted-by":"publisher","DOI":"10.1016\/j.jfda.2014.01.006"},{"key":"ref658\/cit658","doi-asserted-by":"publisher","DOI":"10.2478\/v10019-011-0037-0"},{"key":"ref659\/cit659","doi-asserted-by":"publisher","DOI":"10.1007\/s41664-019-00101-3"},{"key":"ref660\/cit660","doi-asserted-by":"publisher","DOI":"10.1021\/jp046405d"},{"key":"ref661\/cit661","doi-asserted-by":"publisher","DOI":"10.1039\/D0RA04736H"},{"key":"ref662\/cit662","doi-asserted-by":"publisher","DOI":"10.1021\/es060589n"},{"key":"ref663\/cit663","doi-asserted-by":"publisher","DOI":"10.1016\/j.toxlet.2008.06.869"},{"key":"ref664\/cit664","doi-asserted-by":"publisher","DOI":"10.1016\/j.tiv.2011.12.011"},{"key":"ref665\/cit665","doi-asserted-by":"publisher","DOI":"10.1186\/1743-8977-10-15"},{"key":"ref666\/cit666","doi-asserted-by":"publisher","DOI":"10.1016\/j.fct.2019.02.043"},{"key":"ref667\/cit667","doi-asserted-by":"publisher","DOI":"10.1002\/jat.3342"},{"key":"ref668\/cit668","doi-asserted-by":"publisher","DOI":"10.1039\/C6RA28272E"},{"key":"ref669\/cit669","doi-asserted-by":"publisher","DOI":"10.1016\/j.etap.2018.08.003"},{"key":"ref670\/cit670","doi-asserted-by":"publisher","DOI":"10.1155\/2019\/4607531"},{"key":"ref671\/cit671","doi-asserted-by":"publisher","DOI":"10.1016\/j.tox.2005.05.007"},{"key":"ref672\/cit672","doi-asserted-by":"publisher","DOI":"10.1111\/j.1751-1097.2011.01015.x"},{"key":"ref673\/cit673","doi-asserted-by":"publisher","DOI":"10.1002\/chem.200802542"},{"key":"ref674\/cit674","doi-asserted-by":"publisher","DOI":"10.1016\/j.apcatb.2013.05.017"},{"key":"ref675\/cit675","doi-asserted-by":"publisher","DOI":"10.1016\/j.apcatb.2016.05.036"},{"key":"ref676\/cit676","doi-asserted-by":"publisher","DOI":"10.1186\/s12989-015-0101-9"},{"key":"ref677\/cit677","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-09-2496"},{"key":"ref678\/cit678","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0055563"},{"key":"ref679\/cit679","doi-asserted-by":"publisher","DOI":"10.1186\/s12645-017-0026-0"},{"key":"ref680\/cit680","doi-asserted-by":"publisher","DOI":"10.1002\/tcr.10053"},{"key":"ref681\/cit681","doi-asserted-by":"publisher","DOI":"10.3109\/15376516.2013.869783"},{"key":"ref682\/cit682","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcat.2017.07.014"},{"key":"ref683\/cit683","doi-asserted-by":"publisher","DOI":"10.1088\/0957-4484\/21\/29\/295101"},{"key":"ref684\/cit684","doi-asserted-by":"publisher","DOI":"10.1002\/smll.200900466"},{"key":"ref685\/cit685","doi-asserted-by":"publisher","DOI":"10.1039\/b711573c"},{"key":"ref686\/cit686","doi-asserted-by":"publisher","DOI":"10.1039\/b819627c"},{"key":"ref687\/cit687","doi-asserted-by":"publisher","DOI":"10.1021\/ja034830z"},{"key":"ref688\/cit688","doi-asserted-by":"publisher","DOI":"10.1186\/s12645-014-0005-7"},{"key":"ref689\/cit689","doi-asserted-by":"publisher","DOI":"10.3389\/fcell.2017.00090"},{"key":"ref690\/cit690","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbamcr.2016.09.012"},{"key":"ref691\/cit691","doi-asserted-by":"publisher","DOI":"10.18632\/oncotarget.7412"},{"key":"ref692\/cit692","doi-asserted-by":"publisher","DOI":"10.1039\/c0cc02698k"},{"key":"ref693\/cit693","doi-asserted-by":"publisher","DOI":"10.1002\/cphc.201100906"},{"key":"ref694\/cit694","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2012.10.010"},{"key":"ref695\/cit695","doi-asserted-by":"publisher","DOI":"10.1039\/C4NR03848G"},{"key":"ref696\/cit696","doi-asserted-by":"publisher","DOI":"10.1080\/10590501.2019.1555319"},{"key":"ref697\/cit697","doi-asserted-by":"publisher","DOI":"10.1021\/acscatal.7b00189"},{"key":"ref698\/cit698","doi-asserted-by":"publisher","DOI":"10.1021\/acs.chemrev.8b00726"},{"key":"ref699\/cit699","doi-asserted-by":"publisher","DOI":"10.1021\/acs.langmuir.8b01138"},{"key":"ref700\/cit700","doi-asserted-by":"publisher","DOI":"10.1016\/0014-5793(74)80297-8"},{"key":"ref701\/cit701","doi-asserted-by":"publisher","DOI":"10.1021\/acsabm.9b01111"},{"key":"ref702\/cit702","doi-asserted-by":"publisher","DOI":"10.1002\/adhm.201700664"},{"key":"ref703\/cit703","doi-asserted-by":"publisher","DOI":"10.1016\/j.snb.2019.02.030"},{"key":"ref704\/cit704","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2015.00256"},{"key":"ref705\/cit705","first-page":"139","volume-title":"Journal of Nuclear Medicine Technology","author":"Seibert J. A.","year":"2004"},{"key":"ref706\/cit706","doi-asserted-by":"publisher","DOI":"10.1016\/j.radmeas.2007.01.001"},{"key":"ref707\/cit707","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9610(88)80287-3"},{"key":"ref708\/cit708","doi-asserted-by":"publisher","DOI":"10.1259\/0007-1285-63-752-642"},{"key":"ref709\/cit709","doi-asserted-by":"publisher","DOI":"10.1088\/0031-9155\/50\/15\/N01"},{"key":"ref710\/cit710","doi-asserted-by":"publisher","DOI":"10.1177\/153303460700600504"},{"key":"ref711\/cit711","doi-asserted-by":"publisher","DOI":"10.1259\/bjr\/59448833"},{"key":"ref712\/cit712","doi-asserted-by":"publisher","DOI":"10.1118\/1.3455703"},{"key":"ref713\/cit713","doi-asserted-by":"crossref","unstructured":"Hubbell, J. H.; Seltzer, S. M.\n                      Tables of X-Ray Mass Attenuation Coefficients and Mass Energy-Absorption Coefficients 1 KeV to 20 MeV for Elements z = 1 to 92 and 48 Additional Substances of Dosimetric Interest\n                      ; United States, 1995.","DOI":"10.6028\/NIST.IR.5632"},{"key":"ref714\/cit714","author":"Auger P.","year":"1925","journal-title":"Sur Les Rayons \u03b2 Secondaires Produit Dans Un Gaz Par Des Rayons X."},{"key":"ref715\/cit715","doi-asserted-by":"publisher","DOI":"10.1080\/0955300080239552"},{"key":"ref716\/cit716","doi-asserted-by":"publisher","DOI":"10.1016\/S0031-8914(35)90060-X"},{"key":"ref717\/cit717","doi-asserted-by":"publisher","DOI":"10.1118\/1.4881329"},{"key":"ref718\/cit718","doi-asserted-by":"publisher","DOI":"10.1007\/s00259-006-0187-2"},{"key":"ref719\/cit719","doi-asserted-by":"publisher","DOI":"10.1038\/srep00018"},{"key":"ref720\/cit720","doi-asserted-by":"publisher","DOI":"10.1088\/0031-9155\/59\/24\/7675"},{"key":"ref721\/cit721","doi-asserted-by":"publisher","DOI":"10.1039\/C5NR07089A"},{"key":"ref722\/cit722","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-019-50332-8"},{"key":"ref723\/cit723","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejmp.2016.10.015"},{"key":"ref724\/cit724","doi-asserted-by":"publisher","DOI":"10.1093\/jrr\/rru084"},{"key":"ref725\/cit725","doi-asserted-by":"publisher","DOI":"10.1118\/1.3575419"},{"key":"ref726\/cit726","doi-asserted-by":"publisher","DOI":"10.1016\/j.rpor.2009.12.002"},{"key":"ref727\/cit727","doi-asserted-by":"publisher","DOI":"10.1088\/0031-9155\/58\/3\/451"},{"key":"ref728\/cit728","doi-asserted-by":"publisher","DOI":"10.1120\/jacmp.v17i5.6284"},{"key":"ref729\/cit729","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms1786"},{"key":"ref730\/cit730","doi-asserted-by":"publisher","DOI":"10.1038\/nrc1367"},{"key":"ref731\/cit731","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijrobp.2018.10.041"},{"key":"ref732\/cit732","doi-asserted-by":"publisher","DOI":"10.1016\/j.critrevonc.2018.06.005"},{"key":"ref733\/cit733","doi-asserted-by":"publisher","DOI":"10.1001\/jamaoncol.2020.6146"},{"key":"ref734\/cit734","doi-asserted-by":"publisher","DOI":"10.1016\/j.clon.2017.09.007"},{"key":"ref735\/cit735","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/djz101"},{"key":"ref736\/cit736","doi-asserted-by":"publisher","DOI":"10.1002\/onco.13792"},{"key":"ref737\/cit737","doi-asserted-by":"publisher","DOI":"10.1002\/onco.13736"},{"key":"ref738\/cit738","doi-asserted-by":"publisher","DOI":"10.1016\/j.adro.2019.07.018"},{"issue":"4","key":"ref739\/cit739","first-page":"163","volume":"4","author":"Najafi M.","year":"2014","journal-title":"J. Biomed. Phys. Eng."},{"key":"ref740\/cit740","doi-asserted-by":"publisher","DOI":"10.1016\/j.talanta.2018.02.088"},{"key":"ref741\/cit741","doi-asserted-by":"publisher","DOI":"10.1088\/0031-9155\/54\/16\/004"},{"key":"ref742\/cit742","doi-asserted-by":"publisher","DOI":"10.1002\/adhm.201701460"},{"key":"ref743\/cit743","doi-asserted-by":"publisher","DOI":"10.7497\/j.issn.2095-3941.2014.02.003"},{"key":"ref744\/cit744","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1906929116"},{"key":"ref745\/cit745","doi-asserted-by":"publisher","DOI":"10.1177\/1091581815600170"},{"key":"ref746\/cit746","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-10-0978"},{"key":"ref747\/cit747","doi-asserted-by":"publisher","DOI":"10.3390\/cancers12082021"},{"key":"ref748\/cit748","doi-asserted-by":"publisher","DOI":"10.1088\/1361-6528\/aae272"},{"key":"ref749\/cit749","doi-asserted-by":"publisher","DOI":"10.1088\/0957-4484\/22\/28\/285101"},{"key":"ref750\/cit750","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jpca.6b01755"},{"key":"ref751\/cit751","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijrobp.2019.06.605"},{"key":"ref752\/cit752","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejca.2021.01.007"},{"key":"ref753\/cit753","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-16-1297"},{"key":"ref754\/cit754","doi-asserted-by":"publisher","DOI":"10.2217\/fon.12.96"},{"issue":"1","key":"ref755\/cit755","first-page":"443","volume":"34","author":"Pottier A.","year":"2014","journal-title":"Anticancer Res."},{"key":"ref756\/cit756","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jpcc.9b08387"},{"key":"ref757\/cit757","doi-asserted-by":"publisher","DOI":"10.1186\/1748-717X-9-150"},{"key":"ref758\/cit758","doi-asserted-by":"publisher","DOI":"10.1021\/acsabm.9b00615"},{"key":"ref759\/cit759","doi-asserted-by":"publisher","DOI":"10.1016\/j.chemosphere.2011.04.067"},{"key":"ref760\/cit760","doi-asserted-by":"publisher","DOI":"10.1166\/mex.2014.1190"},{"key":"ref761\/cit761","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-017-07753-0"},{"key":"ref762\/cit762","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2008.08.001"},{"key":"ref763\/cit763","doi-asserted-by":"publisher","DOI":"10.1038\/sj.onc.1202211"},{"key":"ref764\/cit764","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2019.119538"},{"key":"ref765\/cit765","doi-asserted-by":"publisher","DOI":"10.1021\/jp1028933"},{"key":"ref766\/cit766","doi-asserted-by":"publisher","DOI":"10.1016\/j.molcata.2015.02.002"},{"key":"ref767\/cit767","doi-asserted-by":"publisher","DOI":"10.3389\/fchem.2021.522708"},{"key":"ref768\/cit768","doi-asserted-by":"publisher","DOI":"10.1016\/j.mtbio.2019.100035"},{"key":"ref769\/cit769","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2011.01.032"},{"key":"ref770\/cit770","doi-asserted-by":"publisher","DOI":"10.1007\/s12094-008-0172-2"},{"key":"ref771\/cit771","doi-asserted-by":"publisher","DOI":"10.3390\/molecules21030342"},{"key":"ref772\/cit772","doi-asserted-by":"publisher","DOI":"10.1002\/smll.202006742"},{"key":"ref773\/cit773","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccr.2019.05.016"},{"key":"ref774\/cit774","doi-asserted-by":"publisher","DOI":"10.1021\/cr900236h"},{"key":"ref775\/cit775","doi-asserted-by":"publisher","DOI":"10.1016\/j.redox.2015.07.006"},{"key":"ref776\/cit776","doi-asserted-by":"publisher","DOI":"10.1016\/j.nano.2009.11.004"},{"key":"ref777\/cit777","doi-asserted-by":"publisher","DOI":"10.1080\/02656730701378684"},{"key":"ref778\/cit778","doi-asserted-by":"publisher","DOI":"10.3109\/02656736.2010.487194"},{"key":"ref779\/cit779","doi-asserted-by":"publisher","DOI":"10.1080\/02656730010001333"},{"key":"ref780\/cit780","doi-asserted-by":"publisher","DOI":"10.3109\/02656736.2015.1099746"},{"key":"ref781\/cit781","doi-asserted-by":"publisher","DOI":"10.1002\/adma.201504617"},{"issue":"16","key":"ref782\/cit782","first-page":"4440","volume":"60","author":"Kong G.","year":"2000","journal-title":"Cancer Res."},{"key":"ref783\/cit783","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2012.12.007"},{"key":"ref784\/cit784","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2012.04.041"},{"key":"ref785\/cit785","doi-asserted-by":"publisher","DOI":"10.1021\/acscentsci.7b00122"},{"key":"ref786\/cit786","doi-asserted-by":"publisher","DOI":"10.1038\/nnano.2014.311"},{"key":"ref787\/cit787","doi-asserted-by":"publisher","DOI":"10.3390\/nano10071411"},{"key":"ref788\/cit788","doi-asserted-by":"publisher","DOI":"10.1039\/C9RA02601K"},{"key":"ref789\/cit789","doi-asserted-by":"publisher","DOI":"10.1002\/adma.201802808"},{"key":"ref790\/cit790","doi-asserted-by":"publisher","DOI":"10.1002\/smll.201702299"},{"key":"ref791\/cit791","doi-asserted-by":"publisher","DOI":"10.1088\/0034-4885\/76\/4\/046401"},{"key":"ref792\/cit792","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.5b04501"},{"key":"ref793\/cit793","doi-asserted-by":"publisher","DOI":"10.7150\/thno.33574"},{"key":"ref794\/cit794","doi-asserted-by":"publisher","DOI":"10.1002\/adhm.201500273"},{"key":"ref795\/cit795","doi-asserted-by":"publisher","DOI":"10.1021\/acssuschemeng.0c04380"},{"key":"ref796\/cit796","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.9b16604"},{"key":"ref797\/cit797","doi-asserted-by":"publisher","DOI":"10.1002\/adma.200802789"},{"key":"ref798\/cit798","doi-asserted-by":"publisher","DOI":"10.1002\/advs.201900471"},{"key":"ref799\/cit799","doi-asserted-by":"publisher","DOI":"10.1088\/1361-648X\/aa60f3"},{"key":"ref800\/cit800","doi-asserted-by":"publisher","DOI":"10.1021\/acsphotonics.8b01021"},{"key":"ref801\/cit801","doi-asserted-by":"publisher","DOI":"10.1007\/s00340-004-1403-z"},{"key":"ref802\/cit802","doi-asserted-by":"publisher","DOI":"10.1038\/am.2017.191"},{"key":"ref803\/cit803","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.physchem.54.011002.103759"},{"key":"ref804\/cit804","doi-asserted-by":"publisher","DOI":"10.1038\/nphoton.2013.238"},{"key":"ref805\/cit805","doi-asserted-by":"publisher","DOI":"10.1038\/s41557-018-0054-3"},{"key":"ref806\/cit806","doi-asserted-by":"publisher","DOI":"10.1021\/acsmaterialslett.1c00081"},{"key":"ref807\/cit807","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jpcc.9b08143"},{"key":"ref808\/cit808","doi-asserted-by":"publisher","DOI":"10.1039\/C8CS00618K"},{"key":"ref809\/cit809","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajme.2011.01.001"},{"key":"ref810\/cit810","doi-asserted-by":"publisher","DOI":"10.1002\/adma.201700448"},{"key":"ref811\/cit811","doi-asserted-by":"publisher","DOI":"10.1002\/wnan.1231"},{"key":"ref812\/cit812","doi-asserted-by":"publisher","DOI":"10.1039\/D1TB00671A"},{"key":"ref813\/cit813","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.5b00021"},{"key":"ref814\/cit814","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-018-26978-1"},{"key":"ref815\/cit815","doi-asserted-by":"publisher","DOI":"10.1016\/j.cej.2020.124314"},{"key":"ref816\/cit816","doi-asserted-by":"publisher","DOI":"10.1186\/s13045-020-00946-7"},{"key":"ref817\/cit817","doi-asserted-by":"publisher","DOI":"10.1111\/imr.12583"},{"key":"ref818\/cit818","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.0c02022"},{"key":"ref819\/cit819","doi-asserted-by":"publisher","DOI":"10.2147\/IJN.S140526"},{"key":"ref820\/cit820","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1906929116"},{"key":"ref821\/cit821","doi-asserted-by":"publisher","DOI":"10.3390\/vaccines9040359"},{"key":"ref822\/cit822","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2017.01.025"},{"key":"ref823\/cit823","doi-asserted-by":"publisher","DOI":"10.2147\/IJN.S49297"},{"key":"ref824\/cit824","doi-asserted-by":"publisher","DOI":"10.1039\/C3NR04448C"},{"key":"ref825\/cit825","doi-asserted-by":"publisher","DOI":"10.7150\/thno.40805"},{"key":"ref826\/cit826","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.8b00893"},{"key":"ref827\/cit827","doi-asserted-by":"publisher","DOI":"10.3109\/02656736.2013.836758"},{"key":"ref828\/cit828","doi-asserted-by":"publisher","DOI":"10.2147\/IJN.S30320"},{"key":"ref829\/cit829","doi-asserted-by":"publisher","DOI":"10.1088\/1361-6528\/ab4241"},{"key":"ref830\/cit830","doi-asserted-by":"publisher","DOI":"10.1007\/s40204-016-0054-6"},{"key":"ref831\/cit831","doi-asserted-by":"publisher","DOI":"10.1016\/j.nantod.2019.100795"},{"key":"ref832\/cit832","doi-asserted-by":"publisher","DOI":"10.1016\/j.addr.2022.114495"},{"key":"ref833\/cit833","doi-asserted-by":"publisher","DOI":"10.1016\/j.nantod.2020.100949"},{"key":"ref834\/cit834","doi-asserted-by":"publisher","DOI":"10.1021\/acs.bioconjchem.0c00029"},{"key":"ref835\/cit835","doi-asserted-by":"publisher","DOI":"10.1002\/jum.14733"},{"key":"ref836\/cit836","doi-asserted-by":"publisher","DOI":"10.1002\/adma.201901989"},{"key":"ref837\/cit837","doi-asserted-by":"publisher","DOI":"10.1038\/s41524-020-00366-8"},{"key":"ref838\/cit838","doi-asserted-by":"publisher","DOI":"10.1038\/s41578-021-00337-5"},{"key":"ref839\/cit839","doi-asserted-by":"publisher","DOI":"10.1016\/j.addr.2022.114172"},{"key":"ref840\/cit840","doi-asserted-by":"publisher","DOI":"10.1038\/s41565-019-0498-7"},{"key":"ref841\/cit841","doi-asserted-by":"publisher","DOI":"10.1016\/j.nantod.2019.06.004"},{"key":"ref842\/cit842","doi-asserted-by":"publisher","DOI":"10.1038\/s41565-020-0759-5"},{"key":"ref843\/cit843","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1919755117"},{"key":"ref844\/cit844","doi-asserted-by":"publisher","DOI":"10.1126\/science.abm5551"},{"key":"ref845\/cit845","doi-asserted-by":"publisher","DOI":"10.1002\/adhm.201901862"}],"container-title":["ACS Nano"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsnano.2c06337","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsnano.2c06337","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,26]],"date-time":"2023-04-26T01:55:42Z","timestamp":1682474142000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acsnano.2c06337"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,11,2]]},"references-count":845,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2022,11,22]]}},"alternative-id":["10.1021\/acsnano.2c06337"],"URL":"https:\/\/doi.org\/10.1021\/acsnano.2c06337","relation":{},"ISSN":["1936-0851","1936-086X"],"issn-type":[{"value":"1936-0851","type":"print"},{"value":"1936-086X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,11,2]]}}}