{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T19:44:58Z","timestamp":1792784698091,"version":"4.5.0"},"reference-count":81,"publisher":"American Chemical Society (ACS)","issue":"4","license":[{"start":{"date-parts":[[2023,2,9]],"date-time":"2023-02-09T00:00:00Z","timestamp":1675900800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2023,2,9]],"date-time":"2023-02-09T00:00:00Z","timestamp":1675900800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2023,2,9]],"date-time":"2023-02-09T00:00:00Z","timestamp":1675900800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/501100008990","name":"Science and Technology Department of Zhejiang Province","doi-asserted-by":"publisher","award":["2021C03036"],"award-info":[{"award-number":["2021C03036"]}],"id":[{"id":"10.13039\/501100008990","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100008990","name":"Science and Technology Department of Zhejiang Province","doi-asserted-by":"publisher","award":["2021C03073"],"award-info":[{"award-number":["2021C03073"]}],"id":[{"id":"10.13039\/501100008990","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100008990","name":"Science and Technology Department of Zhejiang Province","doi-asserted-by":"publisher","award":["2023C03085"],"award-info":[{"award-number":["2023C03085"]}],"id":[{"id":"10.13039\/501100008990","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100018684","name":"National Health Commission of the People's Republic of China","doi-asserted-by":"publisher","award":["WKJ-ZJ-2207"],"award-info":[{"award-number":["WKJ-ZJ-2207"]}],"id":[{"id":"10.13039\/501100018684","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82072126"],"award-info":[{"award-number":["82072126"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012433","name":"Key Project of Application Development Plan of Chongqing City","doi-asserted-by":"publisher","award":["CSTB2021TIAD-KPX0051"],"award-info":[{"award-number":["CSTB2021TIAD-KPX0051"]}],"id":[{"id":"10.13039\/501100012433","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Zhejiang Province","award":["WKJ-ZJ-2207"],"award-info":[{"award-number":["WKJ-ZJ-2207"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ACS Nano"],"published-print":{"date-parts":[[2023,2,28]]},"DOI":"10.1021\/acsnano.2c09931","type":"journal-article","created":{"date-parts":[[2023,2,9]],"date-time":"2023-02-09T14:47:10Z","timestamp":1675954030000},"page":"3528-3548","source":"Crossref","is-referenced-by-count":46,"title":["A Nanotherapy of Octanoic Acid Ameliorates Cardiac Arrest\/Cardiopulmonary Resuscitation-Induced Brain Injury\n                    <i>via<\/i>\n                    RVG29- and Neutrophil Membrane-Mediated Injury Relay Targeting"],"prefix":"10.1021","volume":"17","author":[{"given":"Jingyuan","family":"Yang","sequence":"first","affiliation":[{"name":"Department of Emergency Medicine, Second Affiliated Hospital of Zhejiang University, Key Laboratory of The Diagnosis and Treatment of Severe Trauma and Burns of Zhejiang Province, Clinical Research Center for Emergency and Critical Care Medicine of Zhejiang Province, Hangzhou 310009, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pan","family":"Wang","sequence":"additional","affiliation":[{"name":"School of Pharmacy and Bioengineering, Chongqing University of Technology, Chongqing 400054, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiangkang","family":"Jiang","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine, Second Affiliated Hospital of Zhejiang University, Key Laboratory of The Diagnosis and Treatment of Severe Trauma and Burns of Zhejiang Province, Clinical Research Center for Emergency and Critical Care Medicine of Zhejiang Province, Hangzhou 310009, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiefeng","family":"Xu","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine, Second Affiliated Hospital of Zhejiang University, Key Laboratory of The Diagnosis and Treatment of Severe Trauma and Burns of Zhejiang Province, Clinical Research Center for Emergency and Critical Care Medicine of Zhejiang Province, Hangzhou 310009, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Minhai","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou 510120, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fei","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine, Second Affiliated Hospital of Zhejiang University, Key Laboratory of The Diagnosis and Treatment of Severe Trauma and Burns of Zhejiang Province, Clinical Research Center for Emergency and Critical Care Medicine of Zhejiang Province, Hangzhou 310009, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yao","family":"Lin","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine, Second Affiliated Hospital of Zhejiang University, Key Laboratory of The Diagnosis and Treatment of Severe Trauma and Burns of Zhejiang Province, Clinical Research Center for Emergency and Critical Care Medicine of Zhejiang Province, Hangzhou 310009, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiawei","family":"Tao","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine, Second Affiliated Hospital of Zhejiang University, Key Laboratory of The Diagnosis and Treatment of Severe Trauma and Burns of Zhejiang Province, Clinical Research Center for Emergency and Critical Care Medicine of Zhejiang Province, Hangzhou 310009, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiantao","family":"He","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine, Second Affiliated Hospital of Zhejiang University, Key Laboratory of The Diagnosis and Treatment of Severe Trauma and Burns of Zhejiang Province, Clinical Research Center for Emergency and Critical Care Medicine of Zhejiang Province, Hangzhou 310009, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0852-0687","authenticated-orcid":true,"given":"Xing","family":"Zhou","sequence":"additional","affiliation":[{"name":"School of Pharmacy and Bioengineering, Chongqing University of Technology, Chongqing 400054, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mao","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Emergency Medicine, Second Affiliated Hospital of Zhejiang University, Key Laboratory of The Diagnosis and Treatment of Severe Trauma and Burns of Zhejiang Province, Clinical Research Center for Emergency and Critical Care Medicine of Zhejiang Province, Hangzhou 310009, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2023,2,9]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-022-28418-1"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1001\/jamacardio.2017.0035"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1186\/s12951-021-00784-w"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(21)00953-3"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1001\/jama.295.1.50"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMc091781"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-021-06548-2"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1155\/2020\/8829328"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1016\/j.tcm.2015.10.002"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1007\/s11033-021-06532-5"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1177\/0271678X16642448"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.60311"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1186\/s12986-019-0359-2"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1186\/s13041-021-00842-2"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.23-13-05928.2003"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1016\/j.it.2020.07.004"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1002\/mds.27718"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1016\/j.arr.2020.101128"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmet.2016.08.023"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1002\/bdd.2510140406"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-4159.2011.07245.x"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-2275(20)39899-0"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1038\/nbt.1807"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2009.02.051"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.8b06572"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1016\/j.actbio.2020.01.018"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1016\/j.bioactmat.2020.08.017"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1186\/s13054-017-1670-9"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1016\/j.jns.2011.12.007"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1038\/nri3399"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2012.00132"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1016\/bs.irn.2016.06.001"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1016\/j.it.2016.03.006"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1016\/j.actbio.2014.01.024"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.7150\/thno.45788"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1016\/j.actbio.2019.07.033"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1039\/C5PY00297D"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1038\/nature05901"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2009.09.024"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.2147\/IJN.S132780"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2011.03.013"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.4161\/hv.21321"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.1038\/nbt.4184"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2249.1990.tb08110.x"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.1038\/sj.cr.7290109"},{"key":"ref46\/cit46","doi-asserted-by":"publisher","DOI":"10.1038\/nm.2514"},{"key":"ref47\/cit47","doi-asserted-by":"publisher","DOI":"10.1242\/jcs.039057"},{"key":"ref48\/cit48","doi-asserted-by":"publisher","DOI":"10.1038\/ni.2921"},{"key":"ref49\/cit49","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2012.05.067"},{"key":"ref50\/cit50","doi-asserted-by":"publisher","DOI":"10.3390\/ijms21218019"},{"key":"ref51\/cit51","doi-asserted-by":"publisher","DOI":"10.1021\/am302883m"},{"key":"ref52\/cit52","doi-asserted-by":"publisher","DOI":"10.1039\/c2cs35146c"},{"key":"ref53\/cit53","doi-asserted-by":"publisher","DOI":"10.3390\/polym13162766"},{"key":"ref54\/cit54","doi-asserted-by":"publisher","DOI":"10.1080\/20022727.2018.1488497"},{"key":"ref55\/cit55","doi-asserted-by":"publisher","DOI":"10.2967\/jnumed.110.083220"},{"key":"ref56\/cit56","doi-asserted-by":"publisher","DOI":"10.1002\/btm2.10395"},{"key":"ref57\/cit57","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2021.825572"},{"key":"ref58\/cit58","unstructured":"Vinay, K.; Abul, A.; Jon, A.\n                      The Central Nervous System. Robbins & Cotran Pathologic Basis of Disease\n                      , 10th ed. Elsevier: Philadelphia, 2021; Vol. 2, pp 1241\u20131304."},{"key":"ref59\/cit59","doi-asserted-by":"publisher","DOI":"10.3389\/fnagi.2017.00238"},{"key":"ref60\/cit60","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-018-06988-3"},{"key":"ref61\/cit61","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-018-04221-9"},{"key":"ref62\/cit62","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-12-394309-5.00006-7"},{"key":"ref63\/cit63","doi-asserted-by":"publisher","DOI":"10.1016\/j.molcel.2009.02.013"},{"key":"ref64\/cit64","doi-asserted-by":"publisher","DOI":"10.1002\/glia.20207"},{"key":"ref65\/cit65","doi-asserted-by":"publisher","DOI":"10.1155\/2020\/6978784"},{"key":"ref66\/cit66","doi-asserted-by":"publisher","DOI":"10.3389\/fncel.2018.00366"},{"key":"ref67\/cit67","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.114.011848"},{"key":"ref68\/cit68","doi-asserted-by":"publisher","DOI":"10.1213\/ANE.0000000000000303"},{"key":"ref69\/cit69","first-page":"445","volume":"42","author":"Tarella C.","year":"1982","journal-title":"Cancer Res."},{"key":"ref70\/cit70","doi-asserted-by":"publisher","DOI":"10.1096\/fj.04-3458fje"},{"key":"ref71\/cit71","doi-asserted-by":"publisher","DOI":"10.1186\/2045-8118-10-33"},{"key":"ref72\/cit72","doi-asserted-by":"publisher","DOI":"10.1038\/nprot.2012.131"},{"key":"ref73\/cit73","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M114.621383"},{"key":"ref74\/cit74","doi-asserted-by":"publisher","DOI":"10.1038\/s41565-018-0254-4"},{"key":"ref75\/cit75","doi-asserted-by":"publisher","DOI":"10.1016\/j.resuscitation.2017.01.024"},{"key":"ref76\/cit76","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2019.108817"},{"key":"ref77\/cit77","doi-asserted-by":"publisher","DOI":"10.1016\/S1010-7940(03)00146-5"},{"key":"ref78\/cit78","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuint.2008.12.002"},{"key":"ref79\/cit79","doi-asserted-by":"publisher","DOI":"10.3390\/pharmaceutics13091484"},{"key":"ref80\/cit80","doi-asserted-by":"publisher","DOI":"10.1038\/srep11990"},{"key":"ref81\/cit81","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.111.062257"}],"container-title":["ACS Nano"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsnano.2c09931","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsnano.2c09931","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,3,5]],"date-time":"2023-03-05T03:52:48Z","timestamp":1677988368000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acsnano.2c09931"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,2,9]]},"references-count":81,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2023,2,28]]}},"alternative-id":["10.1021\/acsnano.2c09931"],"URL":"https:\/\/doi.org\/10.1021\/acsnano.2c09931","relation":{},"ISSN":["1936-0851","1936-086X"],"issn-type":[{"value":"1936-0851","type":"print"},{"value":"1936-086X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,2,9]]}}}