{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,11]],"date-time":"2026-11-11T21:04:03Z","timestamp":1794431043326,"version":"4.9.1"},"reference-count":67,"publisher":"American Chemical Society (ACS)","issue":"17","license":[{"start":{"date-parts":[[2023,8,25]],"date-time":"2023-08-25T00:00:00Z","timestamp":1692921600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2023,8,25]],"date-time":"2023-08-25T00:00:00Z","timestamp":1692921600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2023,8,25]],"date-time":"2023-08-25T00:00:00Z","timestamp":1692921600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/501100007162","name":"Guangdong Science and Technology Department","doi-asserted-by":"publisher","award":["2018B030322006"],"award-info":[{"award-number":["2018B030322006"]}],"id":[{"id":"10.13039\/501100007162","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82072062"],"award-info":[{"award-number":["82072062"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Foshan Fourth People?s Hospital","award":["FSSYKF-2020003"],"award-info":[{"award-number":["FSSYKF-2020003"]}]},{"name":"Foshan Fourth People?s Hospital","award":["FSSYKF-2020017"],"award-info":[{"award-number":["FSSYKF-2020017"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ACS Nano"],"published-print":{"date-parts":[[2023,9,12]]},"DOI":"10.1021\/acsnano.3c03456","type":"journal-article","created":{"date-parts":[[2023,8,25]],"date-time":"2023-08-25T12:55:22Z","timestamp":1692968122000},"page":"16770-16786","source":"Crossref","is-referenced-by-count":120,"title":["Sequential Targeting Hybrid Nanovesicles Composed of Chimeric Antigen Receptor T-Cell-Derived Exosomes and Liposomes for Enhanced Cancer Immunochemotherapy"],"prefix":"10.1021","volume":"17","author":[{"given":"Tianchuan","family":"Zhu","sequence":"first","affiliation":[{"name":"Center for Infection and Immunity, Guangdong Engineering Research Center of Molecular Imaging, The Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai 519000, Guangdong, China"},{"name":"Department of Clinical Laboratory, The Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai 519000, Guangdong, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhenxing","family":"Chen","sequence":"additional","affiliation":[{"name":"Center for Infection and Immunity, Guangdong Engineering Research Center of Molecular Imaging, The Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai 519000, Guangdong, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guanmin","family":"Jiang","sequence":"additional","affiliation":[{"name":"Department of Clinical Laboratory, The Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai 519000, Guangdong, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4829-8390","authenticated-orcid":true,"given":"Xi","family":"Huang","sequence":"additional","affiliation":[{"name":"Center for Infection and Immunity, Guangdong Engineering Research Center of Molecular Imaging, The Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai 519000, Guangdong, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2023,8,25]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21708"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21660"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.21.01497"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.21.01710"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.21.01707"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccell.2020.11.005"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1038\/s41590-022-01132-2"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1038\/s41408-021-00536-x"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1002\/adma.202206200"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1002\/adma.202101110"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1038\/s41565-021-00931-2"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1038\/s41573-022-00410-w"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1002\/adma.202106516"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.2c04983"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1002\/adma.202005709"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1016\/j.actbio.2022.11.043"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1002\/adma.201705350"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1002\/adma.201707112"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2021.08.004"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.3390\/cancers13061401"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-019-12321-3"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.3390\/cells11050790"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1002\/advs.202370074"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.2c10845"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.2c06516"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1186\/s12951-021-01148-0"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.3402\/jev.v4.26316"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1002\/jev2.12085"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1021\/acs.accounts.1c00550"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1016\/j.addr.2021.113851"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2109256118"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1038\/s41565-020-0669-6"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.1c04996"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.2c06357"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.202103600"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.0c09681"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1002\/advs.201700611"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1002\/advs.202000515"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-020-18626-y"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2021.120964"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.1002\/adhm.202101202"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.1002\/jev2.12198"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.8b08964"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.1038\/s41596-022-00755-x"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpharm.2005.04.029"},{"key":"ref46\/cit46","doi-asserted-by":"publisher","DOI":"10.3390\/pharmaceutics8030025"},{"key":"ref47\/cit47","doi-asserted-by":"publisher","DOI":"10.1016\/j.bioactmat.2020.12.010"},{"key":"ref48\/cit48","doi-asserted-by":"publisher","DOI":"10.1016\/j.bioactmat.2020.11.016"},{"key":"ref49\/cit49","doi-asserted-by":"publisher","DOI":"10.1002\/advs.202205247"},{"key":"ref50\/cit50","doi-asserted-by":"publisher","DOI":"10.1158\/2159-8290.CD-20-1312"},{"key":"ref51\/cit51","doi-asserted-by":"publisher","DOI":"10.1002\/adma.201705054"},{"key":"ref52\/cit52","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.9b07212"},{"key":"ref53\/cit53","doi-asserted-by":"publisher","DOI":"10.1021\/acs.accounts.0c00518"},{"key":"ref54\/cit54","doi-asserted-by":"publisher","DOI":"10.1152\/ajplung.2000.278.1.L217"},{"key":"ref55\/cit55","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2013.09.013"},{"key":"ref56\/cit56","doi-asserted-by":"publisher","DOI":"10.1186\/s40425-019-0805-8"},{"key":"ref57\/cit57","doi-asserted-by":"publisher","DOI":"10.1186\/s12951-021-01085-y"},{"key":"ref58\/cit58","doi-asserted-by":"publisher","DOI":"10.1088\/1758-5090\/ac8621"},{"key":"ref59\/cit59","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2019.11058"},{"key":"ref60\/cit60","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2021.627932"},{"key":"ref61\/cit61","doi-asserted-by":"publisher","DOI":"10.1158\/2326-6066.CIR-21-0269"},{"key":"ref62\/cit62","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2022.05.027"},{"key":"ref63\/cit63","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccell.2020.07.005"},{"key":"ref64\/cit64","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-020-20696-x"},{"key":"ref65\/cit65","doi-asserted-by":"publisher","DOI":"10.1002\/smll.201903761"},{"key":"ref66\/cit66","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2011.09.025"},{"key":"ref67\/cit67","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2018.08.022"}],"container-title":["ACS Nano"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsnano.3c03456","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsnano.3c03456","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,12]],"date-time":"2023-09-12T06:03:27Z","timestamp":1694498607000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acsnano.3c03456"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,8,25]]},"references-count":67,"journal-issue":{"issue":"17","published-print":{"date-parts":[[2023,9,12]]}},"alternative-id":["10.1021\/acsnano.3c03456"],"URL":"https:\/\/doi.org\/10.1021\/acsnano.3c03456","relation":{"has-part":[{"id-type":"doi","id":"https:\/\/doi.org\/10.1021\/acsnano.3c03456.s001","asserted-by":"subject"}]},"ISSN":["1936-0851","1936-086X"],"issn-type":[{"value":"1936-0851","type":"print"},{"value":"1936-086X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,8,25]]}}}