{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T17:34:11Z","timestamp":1792690451560,"version":"4.5.0"},"reference-count":73,"publisher":"American Chemical Society (ACS)","issue":"24","license":[{"start":{"date-parts":[[2023,10,17]],"date-time":"2023-10-17T00:00:00Z","timestamp":1697500800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003744","name":"Stiftelsen Handlanden Hjalmar Svenssons","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003744","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004359","name":"Vetenskapsr?det","doi-asserted-by":"publisher","award":["2020-04715"],"award-info":[{"award-number":["2020-04715"]}],"id":[{"id":"10.13039\/501100004359","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003743","name":"Adlerbertska Stiftelserna","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003743","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003748","name":"Svenska S?llskapet f?r Medicinsk Forskning","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003748","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001804","name":"Canada Research Chairs","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001804","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000038","name":"Natural Sciences and Engineering Research Council of Canada","doi-asserted-by":"publisher","award":["RGPIN-2020-05722"],"award-info":[{"award-number":["RGPIN-2020-05722"]}],"id":[{"id":"10.13039\/501100000038","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007190","name":"Sveriges Regering","doi-asserted-by":"publisher","award":["ALFGBG-725641"],"award-info":[{"award-number":["ALFGBG-725641"]}],"id":[{"id":"10.13039\/501100007190","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009479","name":"Kungl. Vetenskaps- och Vitterhets-Samh?llet i G?teborg","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100009479","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003400","name":"Ontario Ministry of Research, Innovation and Science","doi-asserted-by":"publisher","award":["ER17-13-081"],"award-info":[{"award-number":["ER17-13-081"]}],"id":[{"id":"10.13039\/501100003400","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100013873","name":"Government of Ontario","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100013873","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100006358","name":"Stiftelsen Blanceflor Boncompagni Ludovisi, f?dd Bildt","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100006358","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ACS Nano"],"published-print":{"date-parts":[[2023,12,26]]},"DOI":"10.1021\/acsnano.3c04633","type":"journal-article","created":{"date-parts":[[2023,10,17]],"date-time":"2023-10-17T11:57:40Z","timestamp":1697543860000},"page":"24710-24724","source":"Crossref","is-referenced-by-count":29,"title":["Ultrastructure and Nanoporosity of Human Bone Shown with Correlative On-Axis Electron and Spectroscopic Tomographies"],"prefix":"10.1021","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5823-6399","authenticated-orcid":true,"given":"Chiara","family":"Micheletti","sequence":"first","affiliation":[{"name":"Department of Materials Science and Engineering, McMaster University, Hamilton L8S 4L7, Ontario, Canada"},{"name":"Department of Biomaterials, Sahlgrenska Academy, University of Gothenburg, G\u00f6teborg 40530, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9876-0467","authenticated-orcid":true,"given":"Furqan A.","family":"Shah","sequence":"additional","affiliation":[{"name":"Department of Biomaterials, Sahlgrenska Academy, University of Gothenburg, G\u00f6teborg 40530, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6974-2577","authenticated-orcid":true,"given":"Anders","family":"Palmquist","sequence":"additional","affiliation":[{"name":"Department of Biomaterials, Sahlgrenska Academy, University of Gothenburg, G\u00f6teborg 40530, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0188-9580","authenticated-orcid":true,"given":"Kathryn","family":"Grandfield","sequence":"additional","affiliation":[{"name":"Department of Materials Science and Engineering, McMaster University, Hamilton L8S 4L7, Ontario, Canada"},{"name":"School of Biomedical Engineering, McMaster University, Hamilton L8S 4L7, Ontario, Canada"},{"name":"Brockhouse Institute for Materials Research, McMaster University, Hamilton L8S 4L7, Ontario, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2023,10,17]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1016\/j.actbio.2014.05.024"},{"key":"ref2\/cit2","first-page":"289","volume-title":"Aspects of protein structure","author":"Hodge A. J.","year":"1963"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0502718103"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1016\/0014-5793(86)80993-0"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1006\/jsbi.1996.0066"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1007\/BF00425873"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1098\/rsif.2011.0880"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0029258"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1016\/j.micron.2013.03.002"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1016\/j.jsb.2014.10.005"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1016\/j.bone.2020.115304"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1016\/j.semcdb.2015.06.008"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1126\/science.aao2189"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1016\/j.yjsbx.2021.100057"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1007\/s00223-018-0454-9"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1180\/0026461036760156"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1016\/j.micron.2008.12.002"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1016\/j.jsb.2020.107615"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1016\/j.jsb.2020.107603"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.202200504"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1917932117"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1002\/anbr.202100162"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1002\/jbmr.4753"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1098\/rsif.2016.0088"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1002\/adma.201501015"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1016\/j.ultramic.2006.04.007"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1021\/nl103172r"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1021\/acsbiomaterials.6b00519"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1002\/admi.201800262"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1016\/j.actbio.2022.02.024"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1016\/S0304-3991(03)00105-0"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1016\/S1369-7021(07)70304-8"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1021\/nn3049957"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1002\/adbi.202100657"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2010.03.025"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1016\/j.micron.2019.102706"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1016\/S8756-3282(97)00053-7"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1016\/j.pmatsci.2007.06.001"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.matsci.28.1.271"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-3495(93)81362-6"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmbbm.2015.03.010"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.1042\/bj3160001"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.1016\/j.jsb.2021.107823"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.2106\/00004623-195234020-00013"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.1007\/BF02555173"},{"key":"ref46\/cit46","doi-asserted-by":"publisher","DOI":"10.3109\/03008209409061969"},{"key":"ref47\/cit47","doi-asserted-by":"publisher","DOI":"10.1016\/S8756-3282(03)00194-7"},{"key":"ref48\/cit48","doi-asserted-by":"publisher","DOI":"10.1006\/jsbi.1993.1003"},{"key":"ref49\/cit49","doi-asserted-by":"publisher","DOI":"10.1016\/S0736-0266(01)00034-1"},{"key":"ref50\/cit50","doi-asserted-by":"publisher","DOI":"10.1016\/0006-3002(57)90327-X"},{"key":"ref51\/cit51","doi-asserted-by":"publisher","DOI":"10.1007\/BF02017554"},{"key":"ref52\/cit52","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.7.4.743"},{"key":"ref53\/cit53","doi-asserted-by":"publisher","DOI":"10.3109\/03008209609005268"},{"key":"ref54\/cit54","doi-asserted-by":"publisher","DOI":"10.1007\/s00223-002-1077-7"},{"key":"ref55\/cit55","doi-asserted-by":"publisher","DOI":"10.1016\/j.jsb.2020.107598"},{"key":"ref56\/cit56","doi-asserted-by":"publisher","DOI":"10.1002\/chem.201302835"},{"key":"ref57\/cit57","doi-asserted-by":"publisher","DOI":"10.1098\/rsif.2010.0213"},{"key":"ref58\/cit58","doi-asserted-by":"publisher","DOI":"10.1098\/rsif.2011.0420"},{"key":"ref59\/cit59","doi-asserted-by":"publisher","DOI":"10.1098\/rsif.2021.0181"},{"key":"ref60\/cit60","doi-asserted-by":"publisher","DOI":"10.1016\/j.ultramic.2008.10.005"},{"key":"ref61\/cit61","doi-asserted-by":"publisher","DOI":"10.1063\/1.2213185"},{"key":"ref62\/cit62","doi-asserted-by":"publisher","DOI":"10.1016\/j.ultramic.2017.01.003"},{"key":"ref63\/cit63","doi-asserted-by":"publisher","DOI":"10.1016\/j.ultramic.2013.03.023"},{"key":"ref64\/cit64","doi-asserted-by":"publisher","DOI":"10.1016\/j.micron.2013.01.004"},{"key":"ref65\/cit65","doi-asserted-by":"publisher","DOI":"10.1016\/j.ultramic.2015.10.007"},{"key":"ref66\/cit66","doi-asserted-by":"publisher","DOI":"10.1016\/0304-3991(89)90322-7"},{"key":"ref67\/cit67","doi-asserted-by":"publisher","DOI":"10.1017\/S1431927614003481"},{"key":"ref68\/cit68","doi-asserted-by":"publisher","DOI":"10.1002\/jbm.a.31856"},{"key":"ref69\/cit69","doi-asserted-by":"publisher","DOI":"10.1016\/j.ultramic.2017.09.011"},{"key":"ref70\/cit70","doi-asserted-by":"publisher","DOI":"10.1016\/j.nimb.2010.02.091"},{"key":"ref71\/cit71","doi-asserted-by":"publisher","DOI":"10.1180\/0026461056950275"},{"key":"ref72\/cit72","doi-asserted-by":"publisher","DOI":"10.1002\/ar.1091850102"},{"key":"ref73\/cit73","volume-title":"X-Ray Mass Attenuation Coefficients, NIST Standard Reference Database 126","author":"Hubbell J. H.","year":"2004"}],"container-title":["ACS Nano"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsnano.3c04633","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsnano.3c04633","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,12,26]],"date-time":"2023-12-26T09:17:34Z","timestamp":1703582254000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acsnano.3c04633"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,10,17]]},"references-count":73,"journal-issue":{"issue":"24","published-print":{"date-parts":[[2023,12,26]]}},"alternative-id":["10.1021\/acsnano.3c04633"],"URL":"https:\/\/doi.org\/10.1021\/acsnano.3c04633","relation":{},"ISSN":["1936-0851","1936-086X"],"issn-type":[{"value":"1936-0851","type":"print"},{"value":"1936-086X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,10,17]]}}}