{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,13]],"date-time":"2026-11-13T02:58:31Z","timestamp":1794538711812,"version":"4.9.1"},"reference-count":36,"publisher":"American Chemical Society (ACS)","issue":"11","license":[{"start":{"date-parts":[[2024,3,7]],"date-time":"2024-03-07T00:00:00Z","timestamp":1709769600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,3,7]],"date-time":"2024-03-07T00:00:00Z","timestamp":1709769600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,3,7]],"date-time":"2024-03-07T00:00:00Z","timestamp":1709769600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/501100007937","name":"Peking University","doi-asserted-by":"publisher","award":["BMU2022XY024"],"award-info":[{"award-number":["BMU2022XY024"]}],"id":[{"id":"10.13039\/501100007937","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007928","name":"Ningbo Municipal Bureau of Science and Technology","doi-asserted-by":"publisher","award":["2022Z142"],"award-info":[{"award-number":["2022Z142"]}],"id":[{"id":"10.13039\/501100007928","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005089","name":"Beijing Municipal Natural Science Foundation","doi-asserted-by":"publisher","award":["7214281"],"award-info":[{"award-number":["7214281"]}],"id":[{"id":"10.13039\/501100005089","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005089","name":"Beijing Municipal Natural Science Foundation","doi-asserted-by":"publisher","award":["J200018"],"award-info":[{"award-number":["J200018"]}],"id":[{"id":"10.13039\/501100005089","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81973259"],"award-info":[{"award-number":["81973259"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82072428"],"award-info":[{"award-number":["82072428"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82173726"],"award-info":[{"award-number":["82173726"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ACS Nano"],"published-print":{"date-parts":[[2024,3,19]]},"DOI":"10.1021\/acsnano.3c11848","type":"journal-article","created":{"date-parts":[[2024,3,7]],"date-time":"2024-03-07T08:54:48Z","timestamp":1709801688000},"page":"8125-8142","source":"Crossref","is-referenced-by-count":52,"title":["Nanomedicines Promote Cartilage Regeneration in Osteoarthritis by Synergistically Enhancing Chondrogenesis of Mesenchymal Stem Cells and Regulating Inflammatory Environment"],"prefix":"10.1021","volume":"18","author":[{"given":"Shi-He","family":"Cui","sequence":"first","affiliation":[{"name":"Beijing Key Laboratory of Molecular Pharmaceutics and New Drug Delivery Systems, State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing, 100191, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi","family":"Yan","sequence":"additional","affiliation":[{"name":"Beijing Key Laboratory of Molecular Pharmaceutics and New Drug Delivery Systems, State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing, 100191, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"An","family":"Lu","sequence":"additional","affiliation":[{"name":"Beijing Key Laboratory of Molecular Pharmaceutics and New Drug Delivery Systems, State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing, 100191, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yun","family":"Dou","sequence":"additional","affiliation":[{"name":"Department of Sports Medicine, Peking University Third Hospital, Beijing, 100191, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhen-Wen","family":"Li","sequence":"additional","affiliation":[{"name":"Beijing Key Laboratory of Molecular Pharmaceutics and New Drug Delivery Systems, State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing, 100191, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ze-Hang","family":"Zhu","sequence":"additional","affiliation":[{"name":"Beijing Key Laboratory of Molecular Pharmaceutics and New Drug Delivery Systems, State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing, 100191, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ming-Ze","family":"Du","sequence":"additional","affiliation":[{"name":"Department of Sports Medicine, Peking University Third Hospital, Beijing, 100191, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yue-Feng","family":"Zhu","sequence":"additional","affiliation":[{"name":"Beijing Key Laboratory of Molecular Pharmaceutics and New Drug Delivery Systems, State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing, 100191, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xin","family":"Chen","sequence":"additional","affiliation":[{"name":"Beijing Key Laboratory of Molecular Pharmaceutics and New Drug Delivery Systems, State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing, 100191, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiangyu","family":"Wang","sequence":"additional","affiliation":[{"name":"Beijing Key Laboratory of Molecular Pharmaceutics and New Drug Delivery Systems, State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing, 100191, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lin-Xia","family":"Jiang","sequence":"additional","affiliation":[{"name":"Beijing Key Laboratory of Molecular Pharmaceutics and New Drug Delivery Systems, State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing, 100191, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yujie","family":"Shi","sequence":"additional","affiliation":[{"name":"Beijing Key Laboratory of Molecular Pharmaceutics and New Drug Delivery Systems, State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing, 100191, China"},{"name":"Laboratory of Innovative Formulations and Pharmaceutical Excipients, Peking University Ningbo Institute of Marine Medicine, Ningbo, 315832, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoyan","family":"Liu","sequence":"additional","affiliation":[{"name":"Beijing Key Laboratory of Molecular Pharmaceutics and New Drug Delivery Systems, State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing, 100191, China"},{"name":"Laboratory of Innovative Formulations and Pharmaceutical Excipients, Peking University Ningbo Institute of Marine Medicine, Ningbo, 315832, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuan-jun","family":"Zhu","sequence":"additional","affiliation":[{"name":"Beijing Key Laboratory of Molecular Pharmaceutics and New Drug Delivery Systems, State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing, 100191, China"},{"name":"Laboratory of Innovative Formulations and Pharmaceutical Excipients, Peking University Ningbo Institute of Marine Medicine, Ningbo, 315832, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dong","family":"Jiang","sequence":"additional","affiliation":[{"name":"Department of Sports Medicine, Peking University Third Hospital, Beijing, 100191, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1651-8977","authenticated-orcid":true,"given":"Jian-Cheng","family":"Wang","sequence":"additional","affiliation":[{"name":"Beijing Key Laboratory of Molecular Pharmaceutics and New Drug Delivery Systems, State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing, 100191, China"},{"name":"Laboratory of Innovative Formulations and Pharmaceutical Excipients, Peking University Ningbo Institute of Marine Medicine, Ningbo, 315832, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2024,3,7]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1177\/03635465211023183"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1039\/D3MH00218G"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1080\/14728222.2023.2185133"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1177\/23259671231155950"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1186\/s13287-017-0632-0"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.3390\/ijms24076405"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1002\/cbin.12008"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.4252\/wjsc.v15.i4.196"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1016\/j.mcna.2019.10.007"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1016\/j.joca.2014.05.021"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1002\/advs.202207490"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1080\/1061186X.2018.1464011"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.2147\/IJN.S381815"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2020.120539"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2014.08.042"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1039\/C6NR04034A"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1002\/adma.201803549"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2020.08.027"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1016\/j.mtbio.2022.100223"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.3390\/molecules23102615"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.34133\/research.0148"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2023.1164137"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2011.00052"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1016\/j.intimp.2021.107823"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1007\/s11033-011-1376-z"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1016\/j.apsb.2022.11.021"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.3892\/ijo.2016.3621"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1172\/JCI118475"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.3390\/ijms22041742"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1002\/advs.202207050"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1016\/j.mtbio.2022.100501"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.3389\/fnmol.2017.00284"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1016\/j.joca.2005.07.014"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1016\/j.joca.2010.05.030"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1016\/j.joca.2010.05.025"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2009.11.008"}],"container-title":["ACS Nano"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsnano.3c11848","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsnano.3c11848","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,3,19]],"date-time":"2024-03-19T06:48:52Z","timestamp":1710830932000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acsnano.3c11848"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,3,7]]},"references-count":36,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2024,3,19]]}},"alternative-id":["10.1021\/acsnano.3c11848"],"URL":"https:\/\/doi.org\/10.1021\/acsnano.3c11848","relation":{"has-part":[{"id-type":"doi","id":"https:\/\/doi.org\/10.1021\/acsnano.3c11848.s001","asserted-by":"subject"}]},"ISSN":["1936-0851","1936-086X"],"issn-type":[{"value":"1936-0851","type":"print"},{"value":"1936-086X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,3,7]]}}}