{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,12]],"date-time":"2026-11-12T09:23:03Z","timestamp":1794475383337,"version":"4.9.1"},"reference-count":96,"publisher":"American Chemical Society (ACS)","issue":"20","license":[{"start":{"date-parts":[[2024,5,10]],"date-time":"2024-05-10T00:00:00Z","timestamp":1715299200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,5,10]],"date-time":"2024-05-10T00:00:00Z","timestamp":1715299200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,5,10]],"date-time":"2024-05-10T00:00:00Z","timestamp":1715299200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/501100003645","name":"National Cancer Center","doi-asserted-by":"publisher","award":["NCC2020FH04"],"award-info":[{"award-number":["NCC2020FH04"]}],"id":[{"id":"10.13039\/501100003645","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100015406","name":"Tianjin Municipal Science and Technology Bureau","doi-asserted-by":"publisher","award":["22JCZDJC00250"],"award-info":[{"award-number":["22JCZDJC00250"]}],"id":[{"id":"10.13039\/501100015406","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012226","name":"Fundamental Research Funds for the Central Universities","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100012226","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["22071144"],"award-info":[{"award-number":["22071144"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["22201299"],"award-info":[{"award-number":["22201299"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["22371147"],"award-info":[{"award-number":["22371147"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["U20A20259"],"award-info":[{"award-number":["U20A20259"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Tianshan Innovation Team Plan of Xinjiang Uygur Autonomous Region","award":["2023D14002"],"award-info":[{"award-number":["2023D14002"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ACS Nano"],"published-print":{"date-parts":[[2024,5,21]]},"DOI":"10.1021\/acsnano.4c01939","type":"journal-article","created":{"date-parts":[[2024,5,10]],"date-time":"2024-05-10T11:37:21Z","timestamp":1715341041000},"page":"13117-13129","source":"Crossref","is-referenced-by-count":29,"title":["Supramolecular 3 in 1: A Lubrication and Co-Delivery System for Synergistic Advanced Osteoarthritis Therapy"],"prefix":"10.1021","volume":"18","author":[{"given":"Meng-Meng","family":"Chen","sequence":"first","affiliation":[{"name":"College of Chemistry, State Key Laboratory of Elemento-Organic Chemistry, Key Laboratory of Functional Polymer Materials (Ministry of Education), Frontiers Science Center for New Organic Matter, Collaborative Innovation Center of Chemical Science and Engineering, Nankai University, Tianjin 300071, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuqiao","family":"Li","sequence":"additional","affiliation":[{"name":"Spine Surgery, Peking University People\u2019s Hospital, Beijing 100044, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yujie","family":"Zhu","sequence":"additional","affiliation":[{"name":"Center for Supramolecular Chemistry & Catalysis and Department of Chemistry, College of Science, Shanghai University, Shanghai 200444, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wen-Chao","family":"Geng","sequence":"additional","affiliation":[{"name":"College of Chemistry, State Key Laboratory of Elemento-Organic Chemistry, Key Laboratory of Functional Polymer Materials (Ministry of Education), Frontiers Science Center for New Organic Matter, Collaborative Innovation Center of Chemical Science and Engineering, Nankai University, Tianjin 300071, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fang-Yuan","family":"Chen","sequence":"additional","affiliation":[{"name":"College of Chemistry, State Key Laboratory of Elemento-Organic Chemistry, Key Laboratory of Functional Polymer Materials (Ministry of Education), Frontiers Science Center for New Organic Matter, Collaborative Innovation Center of Chemical Science and Engineering, Nankai University, Tianjin 300071, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan-Juan","family":"Li","sequence":"additional","affiliation":[{"name":"College of Chemistry, State Key Laboratory of Elemento-Organic Chemistry, Key Laboratory of Functional Polymer Materials (Ministry of Education), Frontiers Science Center for New Organic Matter, Collaborative Innovation Center of Chemical Science and Engineering, Nankai University, Tianjin 300071, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ze-Han","family":"Wang","sequence":"additional","affiliation":[{"name":"College of Chemistry, State Key Laboratory of Elemento-Organic Chemistry, Key Laboratory of Functional Polymer Materials (Ministry of Education), Frontiers Science Center for New Organic Matter, Collaborative Innovation Center of Chemical Science and Engineering, Nankai University, Tianjin 300071, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5588-9607","authenticated-orcid":true,"given":"Xin-Yue","family":"Hu","sequence":"additional","affiliation":[{"name":"College of Chemistry, State Key Laboratory of Elemento-Organic Chemistry, Key Laboratory of Functional Polymer Materials (Ministry of Education), Frontiers Science Center for New Organic Matter, Collaborative Innovation Center of Chemical Science and Engineering, Nankai University, Tianjin 300071, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiong","family":"Tang","sequence":"additional","affiliation":[{"name":"Department of Respiratory, Tianjin Union Medical Center, Tianjin 300121, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5698-3534","authenticated-orcid":true,"given":"Yang","family":"Yu","sequence":"additional","affiliation":[{"name":"Center for Supramolecular Chemistry & Catalysis and Department of Chemistry, College of Science, Shanghai University, Shanghai 200444, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tianwei","family":"Sun","sequence":"additional","affiliation":[{"name":"Spine Surgery, Tianjin Union Medical Center, Tianjin 300121, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0765-5427","authenticated-orcid":true,"given":"Dong-Sheng","family":"Guo","sequence":"additional","affiliation":[{"name":"College of Chemistry, State Key Laboratory of Elemento-Organic Chemistry, Key Laboratory of Functional Polymer Materials (Ministry of Education), Frontiers Science Center for New Organic Matter, Collaborative Innovation Center of Chemical Science and Engineering, Nankai University, Tianjin 300071, China"},{"name":"Xinjiang Key Laboratory of Novel Functional Materials Chemistry, College of Chemistry and Environmental Sciences, Kashi University, Kashi 844000, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2024,5,10]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.chemrev.7b00258"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1002\/adma.201503280"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1002\/chem.201302097"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1038\/nrd.2016.3"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1039\/C4BM00369A"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.6b06040"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1007\/s11426-018-9397-5"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1007\/s11426-022-1243-5"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1038\/s41565-022-01310-1"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1002\/adhm.202302374"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202117075"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202110832"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-023-39914-3"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1016\/j.bioactmat.2021.12.011"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1038\/s41392-023-01668-1"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1002\/cac2.12521"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1186\/s13045-023-01509-2"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1038\/s41578-023-00589-3"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2304081120"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.18632\/oncotarget.16723"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1002\/adma.201800662"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(04)00971-5"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1016\/j.addr.2009.05.006"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1021\/jm3009986"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1016\/j.cclet.2022.107827"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1039\/D1SC01125A"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.3390\/molecules28031241"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.0c09914"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.31635\/ccschem.021.202100964"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1039\/C6CS00898D"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1039\/D0CS00011F"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1021\/accountsmr.3c00130"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.3390\/polym14224855"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.7b01157"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1002\/adma.202203765"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.0c04565"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1016\/j.actbio.2022.04.027"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.202213967"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.1016\/j.supmat.2022.100020"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.1016\/j.cclet.2023.108594"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.1016\/j.actbio.2023.03.039"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202203786"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201900886"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.1002\/adma.202007719"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.1002\/smll.202006223"},{"key":"ref46\/cit46","doi-asserted-by":"publisher","DOI":"10.1038\/s41551-020-0555-4"},{"key":"ref47\/cit47","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2203994119"},{"key":"ref48\/cit48","doi-asserted-by":"publisher","DOI":"10.3390\/molecules22010001"},{"key":"ref49\/cit49","doi-asserted-by":"publisher","DOI":"10.1039\/D0CS00454E"},{"key":"ref50\/cit50","doi-asserted-by":"publisher","DOI":"10.1016\/j.pharmthera.2020.107620"},{"key":"ref51\/cit51","doi-asserted-by":"publisher","DOI":"10.1002\/adma.202104310"},{"key":"ref52\/cit52","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD013273"},{"key":"ref53\/cit53","doi-asserted-by":"publisher","DOI":"10.3389\/fbioe.2022.858656"},{"key":"ref54\/cit54","doi-asserted-by":"publisher","DOI":"10.1002\/adhm.202203245"},{"key":"ref55\/cit55","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.202208189"},{"key":"ref56\/cit56","doi-asserted-by":"publisher","DOI":"10.1002\/smll.202004519"},{"key":"ref57\/cit57","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.3c04241"},{"key":"ref58\/cit58","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMcp1903768"},{"key":"ref59\/cit59","doi-asserted-by":"publisher","DOI":"10.1016\/j.apsb.2022.11.021"},{"key":"ref60\/cit60","doi-asserted-by":"publisher","DOI":"10.1039\/D3MH00218G"},{"key":"ref61\/cit61","doi-asserted-by":"publisher","DOI":"10.1007\/s40544-022-0605-x"},{"key":"ref62\/cit62","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2023.122030"},{"key":"ref63\/cit63","doi-asserted-by":"publisher","DOI":"10.1016\/j.bioactmat.2021.03.022"},{"key":"ref64\/cit64","doi-asserted-by":"publisher","DOI":"10.1007\/s40883-022-00282-x"},{"key":"ref65\/cit65","doi-asserted-by":"publisher","DOI":"10.1002\/adtp.202000088"},{"key":"ref66\/cit66","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.1c09325"},{"key":"ref67\/cit67","doi-asserted-by":"publisher","DOI":"10.1002\/adma.202005513"},{"key":"ref68\/cit68","doi-asserted-by":"publisher","DOI":"10.1080\/1061186X.2018.1464011"},{"key":"ref69\/cit69","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-018-32206-7"},{"key":"ref70\/cit70","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2014.08.042"},{"key":"ref71\/cit71","doi-asserted-by":"publisher","DOI":"10.1080\/10717544.2020.1787555"},{"key":"ref72\/cit72","doi-asserted-by":"publisher","DOI":"10.2174\/1385272824999200510232141"},{"key":"ref73\/cit73","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.1c06510"},{"key":"ref74\/cit74","doi-asserted-by":"publisher","DOI":"10.1016\/j.carbpol.2019.115544"},{"key":"ref75\/cit75","doi-asserted-by":"publisher","DOI":"10.1093\/pm\/pnaa230"},{"key":"ref76\/cit76","doi-asserted-by":"publisher","DOI":"10.3389\/fbioe.2020.00872"},{"key":"ref77\/cit77","doi-asserted-by":"publisher","DOI":"10.1021\/cr200213s"},{"key":"ref78\/cit78","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.1c06031"},{"key":"ref79\/cit79","doi-asserted-by":"publisher","DOI":"10.1038\/s41557-021-00647-9"},{"key":"ref80\/cit80","doi-asserted-by":"publisher","DOI":"10.1002\/sstr.202200067"},{"key":"ref81\/cit81","doi-asserted-by":"publisher","DOI":"10.1002\/adma.201908435"},{"key":"ref82\/cit82","doi-asserted-by":"publisher","DOI":"10.1007\/s40242-022-2204-9"},{"key":"ref83\/cit83","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2020.119931"},{"key":"ref84\/cit84","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.0c01559"},{"key":"ref85\/cit85","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.201807559"},{"key":"ref86\/cit86","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.0c14805"},{"key":"ref87\/cit87","doi-asserted-by":"publisher","DOI":"10.1016\/j.actbio.2016.05.005"},{"key":"ref88\/cit88","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.201300483"},{"key":"ref89\/cit89","doi-asserted-by":"publisher","DOI":"10.1016\/j.drudis.2018.05.023"},{"key":"ref90\/cit90","doi-asserted-by":"publisher","DOI":"10.1016\/j.cej.2020.126004"},{"key":"ref91\/cit91","doi-asserted-by":"publisher","DOI":"10.1016\/j.bone.2005.08.007"},{"key":"ref92\/cit92","doi-asserted-by":"publisher","DOI":"10.1016\/j.joca.2021.12.002"},{"key":"ref93\/cit93","doi-asserted-by":"publisher","DOI":"10.1302\/2058-5241.4.180102"},{"key":"ref94\/cit94","doi-asserted-by":"publisher","DOI":"10.7150\/ijbs.4221"},{"key":"ref95\/cit95","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202100873"},{"key":"ref96\/cit96","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2022.04.037"}],"container-title":["ACS Nano"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsnano.4c01939","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsnano.4c01939","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,21]],"date-time":"2024-05-21T11:34:35Z","timestamp":1716291275000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acsnano.4c01939"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,5,10]]},"references-count":96,"journal-issue":{"issue":"20","published-print":{"date-parts":[[2024,5,21]]}},"alternative-id":["10.1021\/acsnano.4c01939"],"URL":"https:\/\/doi.org\/10.1021\/acsnano.4c01939","relation":{"has-part":[{"id-type":"doi","id":"https:\/\/doi.org\/10.1021\/acsnano.4c01939.s001","asserted-by":"subject"}]},"ISSN":["1936-0851","1936-086X"],"issn-type":[{"value":"1936-0851","type":"print"},{"value":"1936-086X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,5,10]]}}}