{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T15:26:30Z","timestamp":1791473190690,"version":"4.3.4"},"reference-count":52,"publisher":"American Chemical Society (ACS)","issue":"18","license":[{"start":{"date-parts":[[2025,5,1]],"date-time":"2025-05-01T00:00:00Z","timestamp":1746057600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,5,1]],"date-time":"2025-05-01T00:00:00Z","timestamp":1746057600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,5,1]],"date-time":"2025-05-01T00:00:00Z","timestamp":1746057600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/501100006407","name":"Natural Science Foundation of Henan Province","doi-asserted-by":"publisher","award":["242300421089"],"award-info":[{"award-number":["242300421089"]}],"id":[{"id":"10.13039\/501100006407","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002858","name":"China Postdoctoral Science Foundation","doi-asserted-by":"publisher","award":["2023M741015"],"award-info":[{"award-number":["2023M741015"]}],"id":[{"id":"10.13039\/501100002858","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002858","name":"China Postdoctoral Science Foundation","doi-asserted-by":"publisher","award":["GZC20230691"],"award-info":[{"award-number":["GZC20230691"]}],"id":[{"id":"10.13039\/501100002858","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100011447","name":"Science and Technology Department of Henan Province","doi-asserted-by":"publisher","award":["232301420064"],"award-info":[{"award-number":["232301420064"]}],"id":[{"id":"10.13039\/501100011447","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["32071388"],"award-info":[{"award-number":["32071388"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["32271463"],"award-info":[{"award-number":["32271463"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["52073079"],"award-info":[{"award-number":["52073079"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004773","name":"Henan University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004773","id-type":"DOI","asserted-by":"publisher"}]},{"name":"NHMRC Investigator Grant"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ACS Nano"],"published-print":{"date-parts":[[2025,5,13]]},"DOI":"10.1021\/acsnano.4c14573","type":"journal-article","created":{"date-parts":[[2025,5,1]],"date-time":"2025-05-01T23:38:45Z","timestamp":1746142725000},"page":"17309-17322","source":"Crossref","is-referenced-by-count":33,"title":["Glioblastoma Cell Derived Exosomes as a Potent Vaccine Platform Targeting Primary Brain Cancers and Brain Metastases"],"prefix":"10.1021","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2307-1376","authenticated-orcid":true,"given":"Yan","family":"Zou","sequence":"first","affiliation":[{"name":"The Zhongzhou Laboratory for Integrative Biology, Henan-Macquarie University Joint Centre for Biomedical Innovation, Henan Key Laboratory of Brain Targeted Bio-nanomedicine, School of Life Sciences","place":["Kaifeng, China"]},{"name":"Henan University","place":["Kaifeng, China"]},{"name":"Macquarie Medical School, Faculty of Medicine, Human Health Sciences","place":["Sydney, Australia"]},{"name":"Macquarie University","place":["Sydney, Australia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shanshan","family":"Li","sequence":"additional","affiliation":[{"name":"The Zhongzhou Laboratory for Integrative Biology, Henan-Macquarie University Joint Centre for Biomedical Innovation, Henan Key Laboratory of Brain Targeted Bio-nanomedicine, School of Life Sciences","place":["Kaifeng, China"]},{"name":"Henan University","place":["Kaifeng, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yundong","family":"Li","sequence":"additional","affiliation":[{"name":"The Zhongzhou Laboratory for Integrative Biology, Henan-Macquarie University Joint Centre for Biomedical Innovation, Henan Key Laboratory of Brain Targeted Bio-nanomedicine, School of Life Sciences","place":["Kaifeng, China"]},{"name":"Henan University","place":["Kaifeng, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dongya","family":"Zhang","sequence":"additional","affiliation":[{"name":"The Zhongzhou Laboratory for Integrative Biology, Henan-Macquarie University Joint Centre for Biomedical Innovation, Henan Key Laboratory of Brain Targeted Bio-nanomedicine, School of Life Sciences","place":["Kaifeng, China"]},{"name":"Henan University","place":["Kaifeng, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2932-1062","authenticated-orcid":true,"given":"Meng","family":"Zheng","sequence":"additional","affiliation":[{"name":"The Zhongzhou Laboratory for Integrative Biology, Henan-Macquarie University Joint Centre for Biomedical Innovation, Henan Key Laboratory of Brain Targeted Bio-nanomedicine, School of Life Sciences","place":["Kaifeng, China"]},{"name":"Henan University","place":["Kaifeng, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1043-3163","authenticated-orcid":true,"given":"Bingyang","family":"Shi","sequence":"additional","affiliation":[{"name":"The Zhongzhou Laboratory for Integrative Biology, Henan-Macquarie University Joint Centre for Biomedical Innovation, Henan Key Laboratory of Brain Targeted Bio-nanomedicine, School of Life Sciences","place":["Kaifeng, China"]},{"name":"Henan University","place":["Kaifeng, China"]},{"name":"School of Biomedical Engineering","place":["Sydney, Australia"]},{"name":"University of Technology Sydney","place":["Sydney, Australia"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2025,5,1]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1007\/s00401-005-0991-y"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.7150\/thno.22699"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1016\/j.jare.2024.03.024"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1016\/j.semcancer.2022.06.007"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1002\/advs.202301107"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1186\/s13045-022-01247-x"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.4c05065"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1038\/s41578-024-00684-z"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1038\/s41416-023-02194-1"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1002\/cam4.5511"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1007\/s11910-014-0508-y"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1128\/mBio.01683-18"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1093\/neuonc\/noad179.0114"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2019.01208"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1016\/j.bioactmat.2022.10.016"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1002\/adma.202210452"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1186\/s12943-023-01776-0"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.202111670"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1002\/advs.202002787"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1016\/j.matt.2023.01.012"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1002\/smll.202007971"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2024.122697"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2023.07.065"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1002\/adma.202306248"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.0c03386"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1038\/s41392-023-01382-y"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1186\/s40164-021-00220-7"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1002\/advs.202103222"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1016\/j.jare.2023.01.005"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1002\/adma.202104779"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1126\/scitranslmed.abc7804"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1186\/s12951-024-02681-4"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2022.03.038"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1002\/smll.202303073"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2020.120431"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1016\/j.bioactmat.2022.09.017"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1002\/EXP.20210274"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1002\/advs.202201895"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.1016\/j.nantod.2021.101097"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.1002\/adma.202311574"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.1002\/EXP.20220140"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.1002\/adma.202109984"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.1038\/s41551-024-01309-0"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.1038\/s41577-021-00537-8"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2304319120"},{"key":"ref46\/cit46","doi-asserted-by":"publisher","DOI":"10.1126\/sciimmunol.adf8776"},{"key":"ref47\/cit47","doi-asserted-by":"publisher","DOI":"10.1038\/s41565-022-01098-0"},{"key":"ref48\/cit48","doi-asserted-by":"publisher","DOI":"10.1007\/s00018-024-05217-z"},{"key":"ref49\/cit49","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2023.0023"},{"key":"ref50\/cit50","doi-asserted-by":"publisher","DOI":"10.1016\/j.bioactmat.2023.11.007"},{"key":"ref51\/cit51","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2024.122694"},{"key":"ref52\/cit52","doi-asserted-by":"publisher","DOI":"10.1016\/j.molmed.2024.06.009"}],"container-title":["ACS Nano"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsnano.4c14573","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsnano.4c14573","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,13]],"date-time":"2025-05-13T04:22:47Z","timestamp":1747110167000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acsnano.4c14573"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,5,1]]},"references-count":52,"journal-issue":{"issue":"18","published-print":{"date-parts":[[2025,5,13]]}},"alternative-id":["10.1021\/acsnano.4c14573"],"URL":"https:\/\/doi.org\/10.1021\/acsnano.4c14573","relation":{},"ISSN":["1936-0851","1936-086X"],"issn-type":[{"value":"1936-0851","type":"print"},{"value":"1936-086X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,5,1]]}}}