{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,10]],"date-time":"2026-09-10T07:07:28Z","timestamp":1789024048496,"version":"build-2803163510"},"reference-count":60,"publisher":"American Chemical Society (ACS)","issue":"10","license":[{"start":{"date-parts":[[2025,3,5]],"date-time":"2025-03-05T00:00:00Z","timestamp":1741132800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000011","name":"Howard Hughes Medical Institute","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000011","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000066","name":"National Institute of Environmental Health Sciences","doi-asserted-by":"publisher","award":["P30-ES002109"],"award-info":[{"award-number":["P30-ES002109"]}],"id":[{"id":"10.13039\/100000066","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000060","name":"National Institute of Allergy and Infectious Diseases","doi-asserted-by":"publisher","award":["R01 AI132413"],"award-info":[{"award-number":["R01 AI132413"]}],"id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000060","name":"National Institute of Allergy and Infectious Diseases","doi-asserted-by":"publisher","award":["U19 AI142780"],"award-info":[{"award-number":["U19 AI142780"]}],"id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100031022","name":"Center for Cancer Research","doi-asserted-by":"publisher","award":["P30-CA14051"],"award-info":[{"award-number":["P30-CA14051"]}],"id":[{"id":"10.13039\/100031022","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ACS Nano"],"published-print":{"date-parts":[[2025,3,18]]},"DOI":"10.1021\/acsnano.4c16007","type":"journal-article","created":{"date-parts":[[2025,3,5]],"date-time":"2025-03-05T19:45:51Z","timestamp":1741203951000},"page":"9958-9970","source":"Crossref","is-referenced-by-count":15,"title":["Nanobody-Targeted Conditional Antimicrobial Therapeutics"],"prefix":"10.1021","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2342-7977","authenticated-orcid":true,"given":"Chayanon","family":"Ngambenjawong","sequence":"first","affiliation":[{"name":"Koch Institute for Integrative Cancer Research","place":["Cambridge, United States"]},{"name":"Massachusetts Institute of Technology","place":["Cambridge, United States"]},{"name":"Institute for Medical Engineering and Science","place":["Cambridge, United States"]},{"name":"Massachusetts Institute of Technology","place":["Cambridge, United States"]},{"name":"School of Biomolecular Science and Engineering","place":["Rayong, Thailand"]},{"name":"Vidyasirimedhi Institute of Science and Technology (VISTEC)","place":["Rayong, Thailand"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3665-5407","authenticated-orcid":true,"given":"Henry","family":"Ko","sequence":"additional","affiliation":[{"name":"Koch Institute for Integrative Cancer Research","place":["Cambridge, United States"]},{"name":"Massachusetts Institute of Technology","place":["Cambridge, United States"]},{"name":"Institute for Medical Engineering and Science","place":["Cambridge, United States"]},{"name":"Massachusetts Institute of Technology","place":["Cambridge, United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tahoura","family":"Samad","sequence":"additional","affiliation":[{"name":"Koch Institute for Integrative Cancer Research","place":["Cambridge, United States"]},{"name":"Massachusetts Institute of Technology","place":["Cambridge, United States"]},{"name":"Institute for Medical Engineering and Science","place":["Cambridge, United States"]},{"name":"Massachusetts Institute of Technology","place":["Cambridge, United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Novalia","family":"Pishesha","sequence":"additional","affiliation":[{"name":"Koch Institute for Integrative Cancer Research","place":["Cambridge, United States"]},{"name":"Massachusetts Institute of Technology","place":["Cambridge, United States"]},{"name":"Division of Immunology, Boston Children\u2019s Hospital","place":["Boston, United States"]},{"name":"Harvard Medical School","place":["Boston, United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1090-6071","authenticated-orcid":true,"given":"Hidde L.","family":"Ploegh","sequence":"additional","affiliation":[{"name":"Program in Cellular and Molecular Medicine, Boston Children\u2019s Hospital","place":["Boston, United States"]},{"name":"Harvard Medical School","place":["Boston, United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1293-2097","authenticated-orcid":true,"given":"Sangeeta N.","family":"Bhatia","sequence":"additional","affiliation":[{"name":"Koch Institute for Integrative Cancer Research","place":["Cambridge, United States"]},{"name":"Massachusetts Institute of Technology","place":["Cambridge, United States"]},{"name":"Institute for Medical Engineering and Science","place":["Cambridge, United States"]},{"name":"Massachusetts Institute of Technology","place":["Cambridge, United States"]},{"name":"Howard Hughes Medical Institute","place":["Cambridge, United States"]},{"name":"Department of Electrical Engineering and Computer Science","place":["Cambridge, United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2025,3,5]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1016\/j.conctc.2018.08.001"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1016\/j.apsb.2022.02.002"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1001\/jamainternmed.2016.6008"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1128\/aac.00054-22"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-023-05905-z"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1021\/acscentsci.0c00229"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1038\/s41551-021-00698-w"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1016\/j.drudis.2022.03.011"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.7150\/thno.4068"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1021\/jacsau.2c00654"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1021\/acscentsci.0c01448"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1021\/mp100253e"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2020606118"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1016\/j.cej.2024.153978"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1038\/nbt.4181"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jmedchem.0c01704"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1039\/C4NR04249B"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1016\/j.addr.2022.114112"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1126\/scitranslmed.3006682"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1038\/s43018-023-00536-9"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1080\/19420862.2020.1792130"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1158\/2326-6066.CIR-22-0705"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2013-09-511543"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1152\/ajplung.00294.2014"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1155\/2022\/3012218"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20151095"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2020.00499"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.2c04162"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1038\/nrd.2016.268"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1038\/s41573-023-00709-2"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.3390\/cancers15153886"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1093\/protein\/gzv040"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1002\/mco2.193"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1038\/s41578-022-00458-5"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-017-17948-0"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2211065119"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1042\/BJ20090549"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1038\/nature16057"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.1128\/mBio.00202-21"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-05-4199"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0914140107"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.1016\/j.molimm.2014.05.017"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.1016\/j.matbio.2015.09.003"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.1007\/s00018-019-03184-4"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2121778119"},{"key":"ref46\/cit46","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.00985-17"},{"key":"ref47\/cit47","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.2016060606"},{"key":"ref48\/cit48","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1318548111"},{"key":"ref49\/cit49","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2023.05.018"},{"key":"ref50\/cit50","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0200444"},{"key":"ref51\/cit51","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2022.1003871"},{"key":"ref52\/cit52","doi-asserted-by":"publisher","DOI":"10.1038\/s41565-022-01161-w"},{"key":"ref53\/cit53","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(15)00466-1"},{"key":"ref54\/cit54","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpharm.2020.119833"},{"key":"ref55\/cit55","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1203472109"},{"key":"ref56\/cit56","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.00342-19"},{"key":"ref57\/cit57","doi-asserted-by":"publisher","DOI":"10.1126\/science.2916125"},{"key":"ref58\/cit58","doi-asserted-by":"publisher","DOI":"10.1128\/JB.00992-07"},{"key":"ref59\/cit59","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2016.10.128"},{"key":"ref60\/cit60","doi-asserted-by":"publisher","DOI":"10.3791\/1266"}],"container-title":["ACS Nano"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsnano.4c16007","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsnano.4c16007","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,16]],"date-time":"2025-04-16T10:03:06Z","timestamp":1744797786000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acsnano.4c16007"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,3,5]]},"references-count":60,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2025,3,18]]}},"alternative-id":["10.1021\/acsnano.4c16007"],"URL":"https:\/\/doi.org\/10.1021\/acsnano.4c16007","relation":{"has-preprint":[{"id-type":"doi","id":"10.1101\/2024.02.20.580917","asserted-by":"object"}]},"ISSN":["1936-0851","1936-086X"],"issn-type":[{"value":"1936-0851","type":"print"},{"value":"1936-086X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,3,5]]}}}