{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,26]],"date-time":"2026-10-26T17:33:13Z","timestamp":1793035993722,"version":"4.5.0"},"reference-count":45,"publisher":"American Chemical Society (ACS)","issue":"19","license":[{"start":{"date-parts":[[2025,5,7]],"date-time":"2025-05-07T00:00:00Z","timestamp":1746576000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,5,7]],"date-time":"2025-05-07T00:00:00Z","timestamp":1746576000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,5,7]],"date-time":"2025-05-07T00:00:00Z","timestamp":1746576000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2022YFB3808100"],"award-info":[{"award-number":["2022YFB3808100"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100013280","name":"Major Basic Research Project of the Natural Science Foundation of the Jiangsu Higher Education Institutions","doi-asserted-by":"publisher","award":["22KJA180003"],"award-info":[{"award-number":["22KJA180003"]}],"id":[{"id":"10.13039\/501100013280","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["32371476"],"award-info":[{"award-number":["32371476"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012462","name":"Collaborative Innovation Center of Suzhou Nano Science & Technology","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100012462","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ACS Nano"],"published-print":{"date-parts":[[2025,5,20]]},"DOI":"10.1021\/acsnano.4c17712","type":"journal-article","created":{"date-parts":[[2025,5,7]],"date-time":"2025-05-07T18:37:19Z","timestamp":1746643039000},"page":"18214-18226","source":"Crossref","is-referenced-by-count":16,"title":["Artificial Tolerogenic Dendritic Cell-Derived Vesicles Prepared by High-Pressure Homogenization for Potent Immunotherapy of Type 1 Diabetes"],"prefix":"10.1021","volume":"19","author":[{"given":"Rong","family":"Sun","sequence":"first","affiliation":[{"name":"Institute of Functional Nano & Soft Materials (FUNSOM)","place":["Suzhou, China"]},{"name":"Soochow University","place":["Suzhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huaxing","family":"Dai","sequence":"additional","affiliation":[{"name":"Institute of Functional Nano & Soft Materials (FUNSOM)","place":["Suzhou, China"]},{"name":"Soochow University","place":["Suzhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chenlu","family":"Yao","sequence":"additional","affiliation":[{"name":"Institute of Functional Nano & Soft Materials (FUNSOM)","place":["Suzhou, China"]},{"name":"Soochow University","place":["Suzhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heng","family":"Wang","sequence":"additional","affiliation":[{"name":"Institute of Functional Nano & Soft Materials (FUNSOM)","place":["Suzhou, China"]},{"name":"Soochow University","place":["Suzhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bingbing","family":"Wu","sequence":"additional","affiliation":[{"name":"Institute of Functional Nano & Soft Materials (FUNSOM)","place":["Suzhou, China"]},{"name":"Soochow University","place":["Suzhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoyu","family":"Yu","sequence":"additional","affiliation":[{"name":"Institute of Functional Nano & Soft Materials (FUNSOM)","place":["Suzhou, China"]},{"name":"Soochow University","place":["Suzhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fang","family":"Xu","sequence":"additional","affiliation":[{"name":"Institute of Functional Nano & Soft Materials (FUNSOM)","place":["Suzhou, China"]},{"name":"Soochow University","place":["Suzhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8054-3472","authenticated-orcid":true,"given":"Chao","family":"Wang","sequence":"additional","affiliation":[{"name":"Institute of Functional Nano & Soft Materials (FUNSOM)","place":["Suzhou, China"]},{"name":"Soochow University","place":["Suzhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2025,5,7]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.2337\/dc24-S002"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1038\/s41577-023-00985-4"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1126\/science.abh1654"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-024-47918-w"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1016\/j.it.2020.11.001"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2022.121571"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaut.2023.103051"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2022.1054968"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1016\/S2213-8587(20)30104-2"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.2337\/dc11-0472"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2017.01279"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-018-33248-7"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1038\/s41565-020-00810-2"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1186\/s12951-024-02470-z"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1002\/adma.202403199"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.7150\/thno.47865"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1155\/2024\/4775285"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.3389\/fendo.2021.682145"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.2174\/1570159X21666230216095938"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1126\/sciadv.aaw6870"},{"key":"ref21\/cit21","first-page":"263","volume-title":"Emerging Technologies for Nanoparticle Manufacturing","author":"Vinchhi P.","year":"2021"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodchem.2023.136680"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2017.01350"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1111\/imm.13468"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-024-53264-8"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1038\/s41423-020-00623-2"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-024-07752-y"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.2300216"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1038\/s41577-024-00994-x"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1038\/cmi.2015.44"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1038\/srep35343"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1002\/advs.201901728"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-021-04248-x"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.0802167"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1038\/s41401-022-01042-x"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.2337\/db23-0987"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1038\/s41551-023-01138-7"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2024.09.004"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.1002\/stem.3269"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.1126\/sciadv.abf7832"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.1126\/science.abh1657"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.2337\/dc13-0626"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.1111\/dom.15581"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2023.1212641"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.1002\/smll.202301019"}],"container-title":["ACS Nano"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsnano.4c17712","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsnano.4c17712","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,20]],"date-time":"2025-05-20T11:16:09Z","timestamp":1747739769000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acsnano.4c17712"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,5,7]]},"references-count":45,"journal-issue":{"issue":"19","published-print":{"date-parts":[[2025,5,20]]}},"alternative-id":["10.1021\/acsnano.4c17712"],"URL":"https:\/\/doi.org\/10.1021\/acsnano.4c17712","relation":{},"ISSN":["1936-0851","1936-086X"],"issn-type":[{"value":"1936-0851","type":"print"},{"value":"1936-086X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,5,7]]}}}