{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,9]],"date-time":"2026-11-09T23:27:16Z","timestamp":1794266836270,"version":"4.9.0"},"reference-count":65,"publisher":"American Chemical Society (ACS)","issue":"19","license":[{"start":{"date-parts":[[2025,5,6]],"date-time":"2025-05-06T00:00:00Z","timestamp":1746489600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,5,6]],"date-time":"2025-05-06T00:00:00Z","timestamp":1746489600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,5,6]],"date-time":"2025-05-06T00:00:00Z","timestamp":1746489600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/501100002858","name":"China Postdoctoral Science Foundation","doi-asserted-by":"publisher","award":["2024M762032"],"award-info":[{"award-number":["2024M762032"]}],"id":[{"id":"10.13039\/501100002858","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003395","name":"Shanghai Municipal Education Commission","doi-asserted-by":"publisher","award":["2021-01-07-00-02-E00082"],"award-info":[{"award-number":["2021-01-07-00-02-E00082"]}],"id":[{"id":"10.13039\/501100003395","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["52302358"],"award-info":[{"award-number":["52302358"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82172515"],"award-info":[{"award-number":["82172515"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82372441"],"award-info":[{"award-number":["82372441"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ACS Nano"],"published-print":{"date-parts":[[2025,5,20]]},"DOI":"10.1021\/acsnano.5c01332","type":"journal-article","created":{"date-parts":[[2025,5,6]],"date-time":"2025-05-06T02:00:52Z","timestamp":1746496852000},"page":"18364-18385","source":"Crossref","is-referenced-by-count":33,"title":["Remodeling the Senescent Microenvironment for Promoting Osteoporotic Tendon-to-Bone Healing via Synergizing Senolytic Quercetin and Aligned Nanowire-Structured Hydrogels"],"prefix":"10.1021","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2588-6621","authenticated-orcid":true,"given":"Wei","family":"Song","sequence":"first","affiliation":[{"name":"Department of Orthopedic Surgery","place":["Shanghai, PR China"]},{"name":"Shanghai Sixth People\u2019s Hospital Affiliated to Shanghai Jiao Tong University School of Medicine","place":["Shanghai, PR China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wencai","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Surgery","place":["Shanghai, PR China"]},{"name":"Shanghai Sixth People\u2019s Hospital Affiliated to Shanghai Jiao Tong University School of Medicine","place":["Shanghai, PR China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Si-Yi","family":"Li","sequence":"additional","affiliation":[{"name":"State Key Laboratory of High Performance Ceramics and Superfine Microstructure, Shanghai Institute of Ceramics","place":["Shanghai, PR China"]},{"name":"Chinese Academy of Sciences","place":["Shanghai, PR China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuhao","family":"Yu","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Surgery","place":["Shanghai, PR China"]},{"name":"Shanghai Sixth People\u2019s Hospital Affiliated to Shanghai Jiao Tong University School of Medicine","place":["Shanghai, PR China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hui","family":"Xu","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Surgery","place":["Shanghai, PR China"]},{"name":"Shanghai Sixth People\u2019s Hospital Affiliated to Shanghai Jiao Tong University School of Medicine","place":["Shanghai, PR China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tingwang","family":"Shi","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Surgery","place":["Shanghai, PR China"]},{"name":"Shanghai Sixth People\u2019s Hospital Affiliated to Shanghai Jiao Tong University School of Medicine","place":["Shanghai, PR China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0291-109X","authenticated-orcid":true,"given":"Han-Ping","family":"Yu","sequence":"additional","affiliation":[{"name":"State Key Laboratory of High Performance Ceramics and Superfine Microstructure, Shanghai Institute of Ceramics","place":["Shanghai, PR China"]},{"name":"Chinese Academy of Sciences","place":["Shanghai, PR China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8260-7161","authenticated-orcid":true,"given":"Yaohua","family":"He","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Surgery","place":["Shanghai, PR China"]},{"name":"Shanghai Sixth People\u2019s Hospital Affiliated to Shanghai Jiao Tong University School of Medicine","place":["Shanghai, PR China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5044-5046","authenticated-orcid":true,"given":"Ying-Jie","family":"Zhu","sequence":"additional","affiliation":[{"name":"State Key Laboratory of High Performance Ceramics and Superfine Microstructure, Shanghai Institute of Ceramics","place":["Shanghai, PR China"]},{"name":"Chinese Academy of Sciences","place":["Shanghai, PR China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-5203-3073","authenticated-orcid":true,"given":"Weilin","family":"Yu","sequence":"additional","affiliation":[{"name":"Department of Orthopedic Surgery","place":["Shanghai, PR China"]},{"name":"Shanghai Sixth People\u2019s Hospital Affiliated to Shanghai Jiao Tong University School of Medicine","place":["Shanghai, PR China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2025,5,6]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jse.2014.08.001"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1177\/0363546514529644"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.2106\/JBJS.16.00770"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1016\/j.jse.2024.03.014"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1002\/adbi.202300331"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1177\/0363546513518418"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1038\/s41413-024-00351-7"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.22203\/eCM.v024a06"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1016\/j.mtbio.2024.101110"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijbiomac.2024.135388"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.201400828"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1002\/advs.202304090"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1016\/j.actbio.2024.04.001"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1039\/D2CS00513A"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.2217\/rme-2023-0151"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1089\/ten.teb.2019.0131"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1002\/advs.202407251"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1007\/s12274-021-3714-3"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1021\/acsbiomaterials.9b01183"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1088\/1748-605X\/ab1583"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1088\/1758-5090\/aa91ec"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.3390\/gels9090742"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.3390\/ijms22136794"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1039\/C6RA28101J"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1093\/nsr\/nwae076"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1016\/j.arr.2023.101989"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1016\/j.actbio.2022.11.056"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2022.943321"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.3892\/ijmm.2024.5445"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1177\/03635465211059821"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.6b07239"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.8b06096"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1016\/j.cej.2018.11.025"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1016\/j.cej.2020.125666"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1172\/jci.insight.129013"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1186\/s13018-024-04869-8"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1016\/j.arr.2024.102235"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1016\/j.arthro.2021.09.027"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.1002\/adma.202306552"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.1007\/s12015-022-10488-9"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.1002\/advs.202406428"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.1016\/j.omtn.2021.12.026"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.1111\/acel.14400"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.1016\/j.msec.2020.111787"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2022.121606"},{"key":"ref46\/cit46","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2009.11.083"},{"key":"ref47\/cit47","doi-asserted-by":"publisher","DOI":"10.1016\/j.colsurfb.2017.10.002"},{"key":"ref48\/cit48","doi-asserted-by":"publisher","DOI":"10.1016\/j.actbio.2017.03.056"},{"key":"ref49\/cit49","doi-asserted-by":"publisher","DOI":"10.1126\/sciadv.adk6722"},{"key":"ref50\/cit50","doi-asserted-by":"publisher","DOI":"10.1038\/nature16187"},{"key":"ref51\/cit51","doi-asserted-by":"publisher","DOI":"10.1002\/smll.202400598"},{"key":"ref52\/cit52","doi-asserted-by":"publisher","DOI":"10.1111\/acel.12709"},{"key":"ref53\/cit53","doi-asserted-by":"publisher","DOI":"10.1038\/s41413-023-00288-3"},{"key":"ref54\/cit54","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2023.122125"},{"key":"ref55\/cit55","doi-asserted-by":"publisher","DOI":"10.1016\/j.jse.2024.02.026"},{"key":"ref56\/cit56","doi-asserted-by":"publisher","DOI":"10.1016\/j.redox.2023.102649"},{"key":"ref57\/cit57","doi-asserted-by":"publisher","DOI":"10.1177\/0363546518815869"},{"key":"ref58\/cit58","doi-asserted-by":"publisher","DOI":"10.1016\/j.arthro.2023.05.036"},{"key":"ref59\/cit59","doi-asserted-by":"publisher","DOI":"10.1177\/0363546511415659"},{"key":"ref60\/cit60","doi-asserted-by":"publisher","DOI":"10.1038\/nmat4863"},{"key":"ref61\/cit61","doi-asserted-by":"publisher","DOI":"10.1366\/000370208786822179"},{"key":"ref62\/cit62","doi-asserted-by":"publisher","DOI":"10.1002\/chem.201304439"},{"key":"ref63\/cit63","doi-asserted-by":"publisher","DOI":"10.1002\/jcp.29355"},{"key":"ref64\/cit64","doi-asserted-by":"publisher","DOI":"10.1039\/C9TB01516G"},{"key":"ref65\/cit65","doi-asserted-by":"publisher","DOI":"10.1016\/j.jse.2008.09.004"}],"container-title":["ACS Nano"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsnano.5c01332","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsnano.5c01332","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,20]],"date-time":"2025-05-20T07:23:28Z","timestamp":1747725808000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acsnano.5c01332"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,5,6]]},"references-count":65,"journal-issue":{"issue":"19","published-print":{"date-parts":[[2025,5,20]]}},"alternative-id":["10.1021\/acsnano.5c01332"],"URL":"https:\/\/doi.org\/10.1021\/acsnano.5c01332","relation":{"has-part":[{"id-type":"doi","id":"https:\/\/doi.org\/10.1021\/acsnano.5c01332.s001","asserted-by":"subject"}]},"ISSN":["1936-0851","1936-086X"],"issn-type":[{"value":"1936-0851","type":"print"},{"value":"1936-086X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,5,6]]}}}