{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,11]],"date-time":"2026-11-11T23:37:53Z","timestamp":1794440273662,"version":"4.9.1"},"reference-count":69,"publisher":"American Chemical Society (ACS)","issue":"30","license":[{"start":{"date-parts":[[2025,7,22]],"date-time":"2025-07-22T00:00:00Z","timestamp":1753142400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,7,22]],"date-time":"2025-07-22T00:00:00Z","timestamp":1753142400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,7,22]],"date-time":"2025-07-22T00:00:00Z","timestamp":1753142400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2022YFA1105200"],"award-info":[{"award-number":["2022YFA1105200"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100017594","name":"Medical Science and Technology Project of Zhejiang Province","doi-asserted-by":"publisher","award":["2022RC024"],"award-info":[{"award-number":["2022RC024"]}],"id":[{"id":"10.13039\/501100017594","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82402905"],"award-info":[{"award-number":["82402905"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007129","name":"Natural Science Foundation of Shandong Province","doi-asserted-by":"publisher","award":["ZR2023ZD30"],"award-info":[{"award-number":["ZR2023ZD30"]}],"id":[{"id":"10.13039\/501100007129","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Special Support for Postdoctoral ?Chaoyong Program?, International Campus, Zhejiang University"},{"name":"Binjiang Institute of Zhejiang University","award":["ZY202205SMKY007"],"award-info":[{"award-number":["ZY202205SMKY007"]}]},{"name":"Leading Innovative and Entrepreneur Team Introduction Program of Zhejiang","award":["2022R01002"],"award-info":[{"award-number":["2022R01002"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ACS Nano"],"published-print":{"date-parts":[[2025,8,5]]},"DOI":"10.1021\/acsnano.5c07135","type":"journal-article","created":{"date-parts":[[2025,7,22]],"date-time":"2025-07-22T16:09:08Z","timestamp":1753200548000},"page":"27634-27653","source":"Crossref","is-referenced-by-count":23,"title":["Engineered Microalgal Extracellular Vesicles for Enhancing Mitochondrial Homeostasis in Radiodermatitis Prevention"],"prefix":"10.1021","volume":"19","author":[{"given":"Jiarong","family":"Cui","sequence":"first","affiliation":[{"name":"Eye Center, The Second Affiliated Hospital","place":["Hangzhou, China"]},{"name":"Zhejiang University School of Medicine","place":["Hangzhou, China"]},{"name":"Institute of Translational Medicine","place":["Hangzhou, China"]},{"name":"Zhejiang University","place":["Hangzhou, China"]},{"name":"Zhejiang University-Ordos City Etuoke Banner Joint Research Center","place":["Haining, China"]},{"name":"Zhejiang University","place":["Haining, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jia","family":"Dong","sequence":"additional","affiliation":[{"name":"Zhejiang University-University of Edinburgh Institute (ZJU-UoE Institute), Zhejiang University School of Medicine","place":["Haining, China"]},{"name":"Zhejiang University","place":["Haining, China"]},{"name":"Zhejiang University-Ordos City Etuoke Banner Joint Research Center","place":["Haining, China"]},{"name":"Zhejiang University","place":["Haining, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yutong","family":"Lang","sequence":"additional","affiliation":[{"name":"Zhejiang University-University of Edinburgh Institute (ZJU-UoE Institute), Zhejiang University School of Medicine","place":["Haining, China"]},{"name":"Zhejiang University","place":["Haining, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoyang","family":"Liu","sequence":"additional","affiliation":[{"name":"Institute of Translational Medicine","place":["Hangzhou, China"]},{"name":"Zhejiang University","place":["Hangzhou, China"]},{"name":"Zhejiang University-Ordos City Etuoke Banner Joint Research Center","place":["Haining, China"]},{"name":"Zhejiang University","place":["Haining, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuchen","family":"Qi","sequence":"additional","affiliation":[{"name":"Zhejiang University-University of Edinburgh Institute (ZJU-UoE Institute), Zhejiang University School of Medicine","place":["Haining, China"]},{"name":"Zhejiang University","place":["Haining, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7247-1253","authenticated-orcid":true,"given":"Yixin","family":"Zheng","sequence":"additional","affiliation":[{"name":"Zhejiang University-Ordos City Etuoke Banner Joint Research Center","place":["Haining, China"]},{"name":"Zhejiang University","place":["Haining, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruoxi","family":"Wang","sequence":"additional","affiliation":[{"name":"Institute of Translational Medicine","place":["Hangzhou, China"]},{"name":"Zhejiang University","place":["Hangzhou, China"]},{"name":"Zhejiang University-Ordos City Etuoke Banner Joint Research Center","place":["Haining, China"]},{"name":"Zhejiang University","place":["Haining, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huiqun","family":"Hu","sequence":"additional","affiliation":[{"name":"Zhejiang University-Ordos City Etuoke Banner Joint Research Center","place":["Haining, China"]},{"name":"Zhejiang University","place":["Haining, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7319-9570","authenticated-orcid":true,"given":"Min","family":"Zhou","sequence":"additional","affiliation":[{"name":"Eye Center, The Second Affiliated Hospital","place":["Hangzhou, China"]},{"name":"Zhejiang University School of Medicine","place":["Hangzhou, China"]},{"name":"Zhejiang University-University of Edinburgh Institute (ZJU-UoE Institute), Zhejiang University School of Medicine","place":["Haining, China"]},{"name":"Zhejiang University","place":["Haining, China"]},{"name":"Zhejiang University-Ordos City Etuoke Banner Joint Research Center","place":["Haining, China"]},{"name":"Zhejiang University","place":["Haining, China"]},{"name":"Research Center for Life Science and Human Health, Binjiang Institute of Zhejiang University","place":["Hangzhou, China"]},{"name":"Zhejiang University","place":["Hangzhou, China"]},{"name":"State Key Laboratory of Transvascular Implantation Devices","place":["Hangzhou, China"]},{"name":"Zhejiang University","place":["Hangzhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2025,7,22]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1002\/adma.201802244"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21707"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1038\/s41571-022-00652-y"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.21324"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1016\/s0140-6736(24)02319-5"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1002\/adhm.202001615"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1007\/s40257-016-0186-4"},{"issue":"12","key":"ref8\/cit8","first-page":"885","volume":"31","author":"Leventhal J.","year":"2017","journal-title":"Oncology"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.3109\/09553002.2013.765055"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1016\/j.stem.2024.06.007"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1038\/s41419-022-05281-y"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1038\/nature12844"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2024.122891"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1016\/j.cej.2024.156869"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-024-07835-w"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.3402\/jev.v4.27066"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1038\/s44222-024-00255-5"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1126\/science.aau6977"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1002\/jev2.12433"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1016\/j.matt.2024.09.012"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1007\/s10787-022-01115-7"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1039\/D3MH01030A"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.4c05309"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-022-34883-5"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodchem.2023.137963"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1016\/j.biotechadv.2020.107536"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1002\/fpf2.12008"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.2174\/138920108785915111"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1590\/S0100-879X1998000800007"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.2174\/138920105774370607"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1016\/j.fbio.2024.103902"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1155\/2017\/3247528"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1016\/s0014-827x(01)01084-9"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.4c16085"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1002\/jobm.202100391"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1186\/s13287-016-0464-3"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1039\/D4FO00610K"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-018-32497-w"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.3c01502"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.1016\/j.bioactmat.2022.12.009"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.1038\/s41578-024-00672-3"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2024.05.049"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.1016\/j.cej.2023.146238"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-024-47696-5"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.202306554"},{"key":"ref46\/cit46","doi-asserted-by":"publisher","DOI":"10.1016\/j.carbpol.2023.120555"},{"key":"ref47\/cit47","doi-asserted-by":"publisher","DOI":"10.1186\/s42825-024-00165-7"},{"key":"ref48\/cit48","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijbiomac.2018.09.188"},{"key":"ref49\/cit49","doi-asserted-by":"publisher","DOI":"10.1016\/j.carbpol.2024.122348"},{"key":"ref50\/cit50","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-023-38209-x"},{"key":"ref51\/cit51","doi-asserted-by":"publisher","DOI":"10.1002\/smmd.20230027"},{"key":"ref52\/cit52","doi-asserted-by":"publisher","DOI":"10.1002\/smmd.20230044"},{"key":"ref53\/cit53","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijbiomac.2018.09.131"},{"key":"ref54\/cit54","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.4c01625"},{"key":"ref55\/cit55","doi-asserted-by":"publisher","DOI":"10.3390\/antiox12040934"},{"key":"ref56\/cit56","doi-asserted-by":"publisher","DOI":"10.1126\/science.1099320"},{"key":"ref57\/cit57","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9343(00)00412-5"},{"key":"ref58\/cit58","doi-asserted-by":"publisher","DOI":"10.2741\/4555"},{"key":"ref59\/cit59","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-022-05544-w"},{"key":"ref60\/cit60","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-024-52321-6"},{"key":"ref61\/cit61","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms14684"},{"key":"ref62\/cit62","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2012.04.045"},{"key":"ref63\/cit63","doi-asserted-by":"publisher","DOI":"10.1016\/j.ab.2016.10.021"},{"key":"ref64\/cit64","doi-asserted-by":"publisher","DOI":"10.3390\/ijms21145069"},{"key":"ref65\/cit65","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202000451"},{"key":"ref66\/cit66","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202313612"},{"key":"ref67\/cit67","doi-asserted-by":"publisher","DOI":"10.1177\/0885328219862123"},{"key":"ref68\/cit68","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2023.07.036"},{"key":"ref69\/cit69","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1917946117"}],"container-title":["ACS Nano"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsnano.5c07135","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsnano.5c07135","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,5]],"date-time":"2025-08-05T08:11:58Z","timestamp":1754381518000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acsnano.5c07135"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7,22]]},"references-count":69,"journal-issue":{"issue":"30","published-print":{"date-parts":[[2025,8,5]]}},"alternative-id":["10.1021\/acsnano.5c07135"],"URL":"https:\/\/doi.org\/10.1021\/acsnano.5c07135","relation":{"has-part":[{"id-type":"doi","id":"https:\/\/doi.org\/10.1021\/acsnano.5c07135.s001","asserted-by":"subject"},{"id-type":"doi","id":"https:\/\/doi.org\/10.1021\/acsnano.5c07135.s003","asserted-by":"subject"},{"id-type":"doi","id":"https:\/\/doi.org\/10.1021\/acsnano.5c07135.s004","asserted-by":"subject"},{"id-type":"doi","id":"https:\/\/doi.org\/10.1021\/acsnano.5c07135.s005","asserted-by":"subject"},{"id-type":"doi","id":"https:\/\/doi.org\/10.1021\/acsnano.5c07135.s006","asserted-by":"subject"},{"id-type":"doi","id":"https:\/\/doi.org\/10.1021\/acsnano.5c07135.s007","asserted-by":"subject"},{"id-type":"doi","id":"https:\/\/doi.org\/10.1021\/acsnano.5c07135.s008","asserted-by":"subject"},{"id-type":"doi","id":"https:\/\/doi.org\/10.1021\/acsnano.5c07135.s009","asserted-by":"subject"}]},"ISSN":["1936-0851","1936-086X"],"issn-type":[{"value":"1936-0851","type":"print"},{"value":"1936-086X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,7,22]]}}}