{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,6]],"date-time":"2026-11-06T14:22:12Z","timestamp":1793974932422,"version":"4.8.0"},"reference-count":39,"publisher":"American Chemical Society (ACS)","issue":"30","license":[{"start":{"date-parts":[[2025,7,24]],"date-time":"2025-07-24T00:00:00Z","timestamp":1753315200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,7,24]],"date-time":"2025-07-24T00:00:00Z","timestamp":1753315200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,7,24]],"date-time":"2025-07-24T00:00:00Z","timestamp":1753315200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/501100010814","name":"Anhui Provincial Department of Education","doi-asserted-by":"publisher","award":["2022AH050665"],"award-info":[{"award-number":["2022AH050665"]}],"id":[{"id":"10.13039\/501100010814","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["22405009"],"award-info":[{"award-number":["22405009"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["52172276"],"award-info":[{"award-number":["52172276"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003995","name":"Natural Science Foundation of Anhui Province","doi-asserted-by":"publisher","award":["2308085QC87"],"award-info":[{"award-number":["2308085QC87"]}],"id":[{"id":"10.13039\/501100003995","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ACS Nano"],"published-print":{"date-parts":[[2025,8,5]]},"DOI":"10.1021\/acsnano.5c09491","type":"journal-article","created":{"date-parts":[[2025,7,24]],"date-time":"2025-07-24T05:29:31Z","timestamp":1753334971000},"page":"27902-27918","source":"Crossref","is-referenced-by-count":25,"title":["Gelatin Methacryloyl Xerogel Puncture Implants Loaded with Cu\n                    <sub>0.5<\/sub>\n                    Mn\n                    <sub>2.5<\/sub>\n                    O\n                    <sub>4<\/sub>\n                    Nanoparticles Synergizes Cuproptosis and STING Activation for Enhanced Breast Cancer Immunotherapy"],"prefix":"10.1021","volume":"19","author":[{"given":"Yechun","family":"Jiang","sequence":"first","affiliation":[{"name":"School of Pharmaceutical Sciences","place":["Hefei, P. R. China"]},{"name":"Anhui Medical University","place":["Hefei, P. R. China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7400-7243","authenticated-orcid":true,"given":"Weinan","family":"Zhang","sequence":"additional","affiliation":[{"name":"School of Biomedical Engineering, Anhui Provincial Institute of Translational Medicine","place":["Hefei, P. R. China"]},{"name":"Anhui Medical University","place":["Hefei, P. R. China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Litao","family":"Liu","sequence":"additional","affiliation":[{"name":"School of Biomedical Engineering, Anhui Provincial Institute of Translational Medicine","place":["Hefei, P. R. China"]},{"name":"Anhui Medical University","place":["Hefei, P. R. China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yayun","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Critical Care Medicine","place":["Hefei, P. R. China"]},{"name":"The First Affiliated Hospital of Anhui Medical University","place":["Hefei, P. R. China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weiqi","family":"Li","sequence":"additional","affiliation":[{"name":"School of Biomedical Engineering, Anhui Provincial Institute of Translational Medicine","place":["Hefei, P. R. China"]},{"name":"Anhui Medical University","place":["Hefei, P. R. China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun","family":"Liang","sequence":"additional","affiliation":[{"name":"School of Biomedical Engineering, Anhui Provincial Institute of Translational Medicine","place":["Hefei, P. R. China"]},{"name":"Anhui Medical University","place":["Hefei, P. R. China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hui","family":"Shen","sequence":"additional","affiliation":[{"name":"School of Biomedical Engineering, Anhui Provincial Institute of Translational Medicine","place":["Hefei, P. R. China"]},{"name":"Anhui Medical University","place":["Hefei, P. R. China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shu","family":"Fang","sequence":"additional","affiliation":[{"name":"School of Biomedical Engineering, Anhui Provincial Institute of Translational Medicine","place":["Hefei, P. R. China"]},{"name":"Anhui Medical University","place":["Hefei, P. R. China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xianyu","family":"Huang","sequence":"additional","affiliation":[{"name":"School of Biomedical Engineering, Anhui Provincial Institute of Translational Medicine","place":["Hefei, P. R. China"]},{"name":"Anhui Medical University","place":["Hefei, P. R. China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhaoyou","family":"Chu","sequence":"additional","affiliation":[{"name":"Department of Critical Care Medicine","place":["Hefei, P. R. China"]},{"name":"The First Affiliated Hospital of Anhui Medical University","place":["Hefei, P. R. China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lingling","family":"Xu","sequence":"additional","affiliation":[{"name":"School of Biomedical Engineering, Anhui Provincial Institute of Translational Medicine","place":["Hefei, P. R. China"]},{"name":"Anhui Medical University","place":["Hefei, P. R. China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4903-3447","authenticated-orcid":true,"given":"Haisheng","family":"Qian","sequence":"additional","affiliation":[{"name":"School of Biomedical Engineering, Anhui Provincial Institute of Translational Medicine","place":["Hefei, P. R. China"]},{"name":"Anhui Medical University","place":["Hefei, P. R. China"]},{"name":"Anhui Engineering Research Center for Medical Micro-Nano Devices","place":["Hefei, P. R. China"]},{"name":"Anhui Medical University","place":["Hefei, P. R. China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2025,7,24]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1038\/s41568-021-00347-z"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1002\/cac2.12546"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1016\/j.trecan.2024.11.011"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.20517\/2347-9264.2022.98"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1038\/s41577-021-00541-y"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1007\/s10238-024-01501-1"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202423280"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2017.08.027"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1002\/adma.202407425"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1126\/scitranslmed.aay9013"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1186\/s12943-024-02186-6"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1038\/nchembio.1661"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1038\/s41392-023-01624-z"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1016\/j.scib.2023.02.027"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1126\/science.abf0529"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1021\/jacsau.4c00712"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2024.122512"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1038\/s41422-020-00395-4"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2020.108053"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1038\/s41565-023-01498-w"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-023-05770-w"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpharm.2021.121037"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1002\/SMMD.20230012"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1007\/s10895-024-04111-y"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1002\/adma.202404971"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1002\/adma.202212267"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2024.122971"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","unstructured":"Ding, L.; Zhang, R.; Du, W.; Wang, Q.; Pei, D.The Role of cGAS-STING Signaling Pathway in Ferroptosis\n                      J. Adv. Res.\n                      2024 10.1016\/j.jare.2024.12.028.","DOI":"10.1016\/j.jare.2024.12.028"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202411498"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1038\/s41571-019-0319-9"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1002\/advs.202500576"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2025.123201"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1002\/adma.201904914"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.2c08013"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1038\/s41590-021-01120-y"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1016\/j.bioactmat.2022.07.021"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2023.12.058"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1016\/j.scib.2020.07.013"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.1126\/sciimmunol.adi3487"}],"container-title":["ACS Nano"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsnano.5c09491","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsnano.5c09491","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,5]],"date-time":"2025-08-05T08:12:50Z","timestamp":1754381570000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acsnano.5c09491"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7,24]]},"references-count":39,"journal-issue":{"issue":"30","published-print":{"date-parts":[[2025,8,5]]}},"alternative-id":["10.1021\/acsnano.5c09491"],"URL":"https:\/\/doi.org\/10.1021\/acsnano.5c09491","relation":{},"ISSN":["1936-0851","1936-086X"],"issn-type":[{"value":"1936-0851","type":"print"},{"value":"1936-086X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,7,24]]}}}