{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T15:17:32Z","timestamp":1792855052853,"version":"4.5.0"},"reference-count":55,"publisher":"American Chemical Society (ACS)","issue":"22","license":[{"start":{"date-parts":[[2026,5,27]],"date-time":"2026-05-27T00:00:00Z","timestamp":1779840000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,5,27]],"date-time":"2026-05-27T00:00:00Z","timestamp":1779840000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,5,27]],"date-time":"2026-05-27T00:00:00Z","timestamp":1779840000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["32000929"],"award-info":[{"award-number":["32000929"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82104094"],"award-info":[{"award-number":["82104094"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007129","name":"Natural Science Foundation of Shandong Province","doi-asserted-by":"publisher","award":["ZR2020QH196"],"award-info":[{"award-number":["ZR2020QH196"]}],"id":[{"id":"10.13039\/501100007129","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007129","name":"Natural Science Foundation of Shandong Province","doi-asserted-by":"publisher","award":["ZR2020QH351"],"award-info":[{"award-number":["ZR2020QH351"]}],"id":[{"id":"10.13039\/501100007129","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Program for Excellent Sci-tech Innovation Teams of Universities in Anhui Province","award":["2023AH010073"],"award-info":[{"award-number":["2023AH010073"]}]},{"name":"State Key Laboratory of Microbial Technology","award":["SKLMTIJP-2025-03"],"award-info":[{"award-number":["SKLMTIJP-2025-03"]}]},{"name":"Shandong Provincial Program of Taishan Industrial Experts","award":["2019TSCYCX-31"],"award-info":[{"award-number":["2019TSCYCX-31"]}]},{"name":"National Science and Technology Major Special Project- Major New Drug Creation","award":["2019ZX09301-112"],"award-info":[{"award-number":["2019ZX09301-112"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ACS Nano"],"published-print":{"date-parts":[[2026,6,9]]},"DOI":"10.1021\/acsnano.5c19913","type":"journal-article","created":{"date-parts":[[2026,5,27]],"date-time":"2026-05-27T19:52:38Z","timestamp":1779911558000},"page":"15875-15893","source":"Crossref","is-referenced-by-count":4,"title":["Endoplasmic Reticulum-Targeted Biomimetic Nanoparticles Potentiate the Immunotherapy of Triple-Negative Breast Cancer by Improving Immunogenicity and Eliminating Immune Resistance"],"prefix":"10.1021","volume":"20","author":[{"given":"Shangui","family":"Liu","sequence":"first","affiliation":[{"name":"Department of Pharmaceutics, Key Laboratory of Chemical Biology (Ministry of Education), NMPA Key Laboratory for Technology Research and Evaluation of Drug Products, School of Pharmaceutical Sciences, Cheeloo College of Medicine","place":["Jinan, P.R. China"]},{"name":"Shandong University","place":["Jinan, P.R. China"]},{"name":"National Glycoengineering Research Center","place":["Qingdao, China"]},{"name":"Shandong University","place":["Qingdao, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cheng","family":"Zhang","sequence":"additional","affiliation":[{"name":"National Glycoengineering Research Center","place":["Qingdao, China"]},{"name":"Shandong University","place":["Qingdao, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qixiang","family":"Feng","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutics, Key Laboratory of Chemical Biology (Ministry of Education), NMPA Key Laboratory for Technology Research and Evaluation of Drug Products, School of Pharmaceutical Sciences, Cheeloo College of Medicine","place":["Jinan, P.R. China"]},{"name":"Shandong University","place":["Jinan, P.R. China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianbo","family":"Ji","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutics, Key Laboratory of Chemical Biology (Ministry of Education), NMPA Key Laboratory for Technology Research and Evaluation of Drug Products, School of Pharmaceutical Sciences, Cheeloo College of Medicine","place":["Jinan, P.R. China"]},{"name":"Shandong University","place":["Jinan, P.R. China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuewu","family":"Xie","sequence":"additional","affiliation":[{"name":"School of Pharmacy","place":["Wuhu, China"]},{"name":"Wannan Medical College","place":["Wuhu, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9480-9596","authenticated-orcid":true,"given":"Yi","family":"Hao","sequence":"additional","affiliation":[{"name":"National Glycoengineering Research Center","place":["Qingdao, China"]},{"name":"Shandong University","place":["Qingdao, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9874-5892","authenticated-orcid":true,"given":"Hailong","family":"Wang","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Microbial Technology","place":["Qingdao, China"]},{"name":"Shandong University","place":["Qingdao, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4373-3090","authenticated-orcid":true,"given":"Haining","family":"Tan","sequence":"additional","affiliation":[{"name":"National Glycoengineering Research Center","place":["Qingdao, China"]},{"name":"Shandong University","place":["Qingdao, China"]},{"name":"NMPA Key Laboratory for Quality Research and Evaluation of Carbohydrate-Based Medicine","place":["Qingdao, China"]},{"name":"Shandong University","place":["Qingdao, China"]},{"name":"Shandong Freda Pharmaceutical Group Co. Ltd.","place":["Jinan, China"]},{"name":"Shandong Key Laboratory of Carbohydrate and Carbohydrate-conjugate Drugs","place":["Jinan, China"]},{"name":"State Key Laboratory of Microbial Technology","place":["Qingdao, China"]},{"name":"Shandong University","place":["Qingdao, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3860-948X","authenticated-orcid":true,"given":"Guangxi","family":"Zhai","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutics, Key Laboratory of Chemical Biology (Ministry of Education), NMPA Key Laboratory for Technology Research and Evaluation of Drug Products, School of Pharmaceutical Sciences, Cheeloo College of Medicine","place":["Jinan, P.R. China"]},{"name":"Shandong University","place":["Jinan, P.R. China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2026,5,27]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21834"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21863"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1038\/s41591-025-03502-3"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2207201119"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1136\/bmj-2022-071674"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1038\/s41591-023-02677-x"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccell.2025.01.007"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1038\/s41568-024-00705-7"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1002\/advs.202205247"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1002\/adma.202314309"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2024.09.032"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2024.3056"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-024-53906-x"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1126\/sciadv.adr1728"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.4c11636"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.4c10119"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-024-53010-0"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1038\/s41590-022-01132-2"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1038\/nrc3380"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2022.121433"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2023.11.058"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.1c11886"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1002\/adhm.202301728"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1002\/adma.202310964"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1002\/adma.202501953"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-019-10562-w"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.3c01446"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2025.114059"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1016\/j.nantod.2022.101466"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-023-39035-x"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-024-48597-3"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202414146"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.202504621"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2016.08.032"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2017.02.011"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1126\/sciadv.abq4722"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-019-0987-8"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1002\/smtd.202200898"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.1016\/j.ebiom.2024.105070"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.2c11037"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.202307756"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2023.12.056"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.1039\/D0NH00034E"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpharm.2019.03.037"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.1002\/adma.202302639"},{"key":"ref46\/cit46","doi-asserted-by":"publisher","DOI":"10.1038\/s41392-025-02217-8"},{"key":"ref47\/cit47","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.5c06202"},{"key":"ref48\/cit48","doi-asserted-by":"publisher","DOI":"10.1016\/j.colsurfa.2025.137603"},{"key":"ref49\/cit49","doi-asserted-by":"publisher","DOI":"10.1038\/s41565-021-00858-8"},{"key":"ref50\/cit50","doi-asserted-by":"publisher","DOI":"10.1016\/j.nantod.2021.101356"},{"key":"ref51\/cit51","doi-asserted-by":"publisher","DOI":"10.1039\/D3BM00781B"},{"key":"ref52\/cit52","doi-asserted-by":"publisher","DOI":"10.1038\/s41551-021-00826-6"},{"key":"ref53\/cit53","doi-asserted-by":"publisher","DOI":"10.3390\/ijms21155531"},{"key":"ref54\/cit54","doi-asserted-by":"publisher","DOI":"10.1038\/nature18935"},{"key":"ref55\/cit55","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2022.121832"}],"container-title":["ACS Nano"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsnano.5c19913","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsnano.5c19913","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,9]],"date-time":"2026-06-09T08:17:12Z","timestamp":1780993032000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acsnano.5c19913"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5,27]]},"references-count":55,"journal-issue":{"issue":"22","published-print":{"date-parts":[[2026,6,9]]}},"alternative-id":["10.1021\/acsnano.5c19913"],"URL":"https:\/\/doi.org\/10.1021\/acsnano.5c19913","relation":{},"ISSN":["1936-0851","1936-086X"],"issn-type":[{"value":"1936-0851","type":"print"},{"value":"1936-086X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,5,27]]}}}