{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,11]],"date-time":"2026-11-11T05:02:07Z","timestamp":1794373327917,"version":"4.9.0"},"reference-count":71,"publisher":"American Chemical Society (ACS)","issue":"14","license":[{"start":{"date-parts":[[2026,3,30]],"date-time":"2026-03-30T00:00:00Z","timestamp":1774828800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,3,30]],"date-time":"2026-03-30T00:00:00Z","timestamp":1774828800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,3,30]],"date-time":"2026-03-30T00:00:00Z","timestamp":1774828800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/501100002858","name":"China Postdoctoral Science Foundation","doi-asserted-by":"publisher","award":["2022M711952"],"award-info":[{"award-number":["2022M711952"]}],"id":[{"id":"10.13039\/501100002858","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002858","name":"China Postdoctoral Science Foundation","doi-asserted-by":"publisher","award":["2022TQ0198"],"award-info":[{"award-number":["2022TQ0198"]}],"id":[{"id":"10.13039\/501100002858","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82201169"],"award-info":[{"award-number":["82201169"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82271078"],"award-info":[{"award-number":["82271078"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82471090"],"award-info":[{"award-number":["82471090"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82530033"],"award-info":[{"award-number":["82530033"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007129","name":"Natural Science Foundation of Shandong Province","doi-asserted-by":"publisher","award":["2601010520249H"],"award-info":[{"award-number":["2601010520249H"]}],"id":[{"id":"10.13039\/501100007129","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007129","name":"Natural Science Foundation of Shandong Province","doi-asserted-by":"publisher","award":["ZR2024QH580"],"award-info":[{"award-number":["ZR2024QH580"]}],"id":[{"id":"10.13039\/501100007129","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Youth Beijing Scholar","award":["076"],"award-info":[{"award-number":["076"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ACS Nano"],"published-print":{"date-parts":[[2026,4,14]]},"DOI":"10.1021\/acsnano.5c20902","type":"journal-article","created":{"date-parts":[[2026,3,30]],"date-time":"2026-03-30T04:57:12Z","timestamp":1774846632000},"page":"11055-11073","source":"Crossref","is-referenced-by-count":14,"title":["Dual-Pronged Strategy on Autoimmune Uveitis by Topical Application of Bioactive Carbon Dots from Natural Herbs"],"prefix":"10.1021","volume":"20","author":[{"given":"Baorui","family":"Chu","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, Qilu Hospital, Cheeloo College of Medicine","place":["Jinan, China"]},{"name":"Shandong University","place":["Jinan, China"]},{"name":"Beijing Institute of Ophthalmology, Beijing Tongren Eye Center, Beijing Tongren Hospital, Beijing Ophthalmology & Visual Sciences Key Laboratory","place":["Beijing, China"]},{"name":"Capital Medical University","place":["Beijing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Can","family":"Li","sequence":"additional","affiliation":[{"name":"Key Laboratory for Liquid\u2212Solid Structural Evolution and Processing of Materials, Ministry of Education","place":["Jinan, China"]},{"name":"Shandong University","place":["Jinan, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Helei","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Qilu Hospital, Cheeloo College of Medicine","place":["Jinan, China"]},{"name":"Shandong University","place":["Jinan, China"]},{"name":"School of Instrumentation and Optoelectronic Engineering","place":["Beijing, China"]},{"name":"Beihang University","place":["Beijing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongkun","family":"Fang","sequence":"additional","affiliation":[{"name":"Department of Scientific Research Management, Weifang People\u2019s Hospital","place":["Weifang, China"]},{"name":"Shandong Second Medical University","place":["Weifang, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xianyang","family":"Liu","sequence":"additional","affiliation":[{"name":"Beijing Institute of Ophthalmology, Beijing Tongren Eye Center, Beijing Tongren Hospital, Beijing Ophthalmology & Visual Sciences Key Laboratory","place":["Beijing, China"]},{"name":"Capital Medical University","place":["Beijing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chao","family":"Wu","sequence":"additional","affiliation":[{"name":"Beijing Institute of Ophthalmology, Beijing Tongren Eye Center, Beijing Tongren Hospital, Beijing Ophthalmology & Visual Sciences Key Laboratory","place":["Beijing, China"]},{"name":"Capital Medical University","place":["Beijing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fan","family":"Cao","sequence":"additional","affiliation":[{"name":"Beijing Institute of Ophthalmology, Beijing Tongren Eye Center, Beijing Tongren Hospital, Beijing Ophthalmology & Visual Sciences Key Laboratory","place":["Beijing, China"]},{"name":"Capital Medical University","place":["Beijing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuhao","family":"Zeng","sequence":"additional","affiliation":[{"name":"Beijing Institute of Ophthalmology, Beijing Tongren Eye Center, Beijing Tongren Hospital, Beijing Ophthalmology & Visual Sciences Key Laboratory","place":["Beijing, China"]},{"name":"Capital Medical University","place":["Beijing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yakun","family":"Wang","sequence":"additional","affiliation":[{"name":"Beijing Institute of Ophthalmology, Beijing Tongren Eye Center, Beijing Tongren Hospital, Beijing Ophthalmology & Visual Sciences Key Laboratory","place":["Beijing, China"]},{"name":"Capital Medical University","place":["Beijing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinyuan","family":"Chen","sequence":"additional","affiliation":[{"name":"Beijing Institute of Ophthalmology, Beijing Tongren Eye Center, Beijing Tongren Hospital, Beijing Ophthalmology & Visual Sciences Key Laboratory","place":["Beijing, China"]},{"name":"Capital Medical University","place":["Beijing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhiqi","family":"Zhang","sequence":"additional","affiliation":[{"name":"Beijing Institute of Ophthalmology, Beijing Tongren Eye Center, Beijing Tongren Hospital, Beijing Ophthalmology & Visual Sciences Key Laboratory","place":["Beijing, China"]},{"name":"Capital Medical University","place":["Beijing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shangze","family":"Gao","sequence":"additional","affiliation":[{"name":"Beijing Institute of Ophthalmology, Beijing Tongren Eye Center, Beijing Tongren Hospital, Beijing Ophthalmology & Visual Sciences Key Laboratory","place":["Beijing, China"]},{"name":"Capital Medical University","place":["Beijing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rui","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Qilu Hospital, Cheeloo College of Medicine","place":["Jinan, China"]},{"name":"Shandong University","place":["Jinan, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7866-4689","authenticated-orcid":true,"given":"Yanyan","family":"Jiang","sequence":"additional","affiliation":[{"name":"Key Laboratory for Liquid\u2212Solid Structural Evolution and Processing of Materials, Ministry of Education","place":["Jinan, China"]},{"name":"Shandong University","place":["Jinan, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianqiao","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Qilu Hospital, Cheeloo College of Medicine","place":["Jinan, China"]},{"name":"Shandong University","place":["Jinan, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7796-8891","authenticated-orcid":true,"given":"Shengping","family":"Hou","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Qilu Hospital, Cheeloo College of Medicine","place":["Jinan, China"]},{"name":"Shandong University","place":["Jinan, China"]},{"name":"Beijing Institute of Ophthalmology, Beijing Tongren Eye Center, Beijing Tongren Hospital, Beijing Ophthalmology & Visual Sciences Key Laboratory","place":["Beijing, China"]},{"name":"Capital Medical University","place":["Beijing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2026,3,30]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1038\/s41584-024-01181-x"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2014.09.025"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(16)31339-3"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1016\/j.semarthrit.2019.06.004"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1001\/jamaophthalmol.2022.5685"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1007\/s11882-013-0409-1"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1001\/jamaophthalmol.2024.2439"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2019.08.053"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1111\/imm.13479"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-019-12780-8"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1016\/j.preteyeres.2015.06.003"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2316161121"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1186\/s12974-023-02983-8"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1002\/btm2.10460"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1186\/1742-2094-10-149"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1002\/adma.202503576"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1007\/s40820-024-01323-6"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1039\/D3CS00655G"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.8b04022"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1002\/adma.201805368"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201712469"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1016\/j.phymed.2024.156138"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1186\/s12951-024-02426-3"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodchem.2023.135496"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1002\/ptr.6517"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1186\/s12951-021-00847-y"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.1c16679"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1002\/advs.201903525"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1002\/adhm.201800995"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhazmat.2021.125091"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1016\/j.cej.2018.09.100"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1002\/adma.202110653"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1016\/j.envres.2023.117771"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1039\/D0CS00579G"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1016\/j.bios.2024.116020"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1820387116"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1016\/j.cej.2025.170369"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1002\/smll.202205754"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2019.02.007"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.1016\/j.tins.2020.03.012"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.1186\/s12974-019-1505-5"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.1016\/j.redox.2022.102297"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.202208-1603OC"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.1016\/j.redox.2024.103247"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.4c08157"},{"key":"ref46\/cit46","doi-asserted-by":"publisher","DOI":"10.1186\/s12974-022-02633-5"},{"key":"ref47\/cit47","doi-asserted-by":"publisher","DOI":"10.1186\/s12974-022-02474-2"},{"key":"ref48\/cit48","doi-asserted-by":"publisher","DOI":"10.1016\/j.phrs.2013.07.010"},{"key":"ref49\/cit49","doi-asserted-by":"publisher","DOI":"10.1002\/adma.202201322"},{"key":"ref50\/cit50","doi-asserted-by":"publisher","DOI":"10.1038\/s41573-025-01145-0"},{"key":"ref51\/cit51","doi-asserted-by":"publisher","DOI":"10.1016\/j.redox.2024.103342"},{"key":"ref52\/cit52","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkt243"},{"key":"ref53\/cit53","doi-asserted-by":"publisher","DOI":"10.1038\/s41573-018-0008-x"},{"key":"ref54\/cit54","doi-asserted-by":"publisher","DOI":"10.1016\/j.preteyeres.2024.101245"},{"key":"ref55\/cit55","doi-asserted-by":"publisher","DOI":"10.1186\/s12974-021-02080-8"},{"key":"ref56\/cit56","doi-asserted-by":"publisher","DOI":"10.1016\/j.preteyeres.2012.08.004"},{"key":"ref57\/cit57","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-024-53528-3"},{"key":"ref58\/cit58","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD013818.pub2"},{"key":"ref59\/cit59","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2021.11.013"},{"key":"ref60\/cit60","doi-asserted-by":"publisher","DOI":"10.1016\/j.redox.2024.103056"},{"key":"ref61\/cit61","doi-asserted-by":"publisher","DOI":"10.1016\/j.phrs.2015.10.001"},{"key":"ref62\/cit62","doi-asserted-by":"publisher","DOI":"10.1016\/j.bcp.2007.01.015"},{"key":"ref63\/cit63","doi-asserted-by":"publisher","DOI":"10.1016\/j.biortech.2025.133405"},{"key":"ref64\/cit64","doi-asserted-by":"publisher","DOI":"10.1016\/j.cej.2023.142338"},{"key":"ref65\/cit65","doi-asserted-by":"publisher","DOI":"10.3390\/nano11071812"},{"key":"ref66\/cit66","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202214042"},{"key":"ref67\/cit67","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2025.1600673"},{"key":"ref68\/cit68","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.64.13.19"},{"key":"ref69\/cit69","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-60761-720-4_22"},{"key":"ref70\/cit70","doi-asserted-by":"publisher","DOI":"10.3109\/09273949509085035"},{"key":"ref71\/cit71","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodchem.2025.147058"}],"container-title":["ACS Nano"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsnano.5c20902","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsnano.5c20902","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,14]],"date-time":"2026-04-14T08:13:02Z","timestamp":1776154382000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acsnano.5c20902"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3,30]]},"references-count":71,"journal-issue":{"issue":"14","published-print":{"date-parts":[[2026,4,14]]}},"alternative-id":["10.1021\/acsnano.5c20902"],"URL":"https:\/\/doi.org\/10.1021\/acsnano.5c20902","relation":{"has-part":[{"id-type":"doi","id":"https:\/\/doi.org\/10.1021\/acsnano.5c20902.s001","asserted-by":"subject"}]},"ISSN":["1936-0851","1936-086X"],"issn-type":[{"value":"1936-0851","type":"print"},{"value":"1936-086X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,3,30]]}}}