{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T23:17:46Z","timestamp":1788218266956,"version":"build-2803163510"},"reference-count":34,"publisher":"American Chemical Society (ACS)","issue":"33","license":[{"start":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T00:00:00Z","timestamp":1786579200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T00:00:00Z","timestamp":1786579200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T00:00:00Z","timestamp":1786579200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/na","name":"Startup Fund for Young Faculty at SJTU","doi-asserted-by":"publisher","award":["25X010502632"],"award-info":[{"award-number":["25X010502632"]}],"id":[{"id":"10.13039\/na","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/na","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["52177218"],"award-info":[{"award-number":["52177218"]}],"id":[{"id":"10.13039\/na","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/na","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["52577237"],"award-info":[{"award-number":["52577237"]}],"id":[{"id":"10.13039\/na","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,8,25]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>The introduction of weakly solvating additives (WSAs) into aqueous electrolytes holds significant potential in promoting the desolvation kinetics of Zn2+ and reducing polarization. However, the current strategy of WSA screening primarily depends on trial-and-error experiments and theoretical calculations. This study reveals that, among various molecular features, the electrostatic potential minimum (ESPmin) exhibits the strongest correlation with the desolvation activation energy (Ea), demonstrating that ESPmin could serve as an effective descriptor for screening WSAs. Herein, we propose a data-driven screening strategy based on ESPmin, in which ESPmin can be accurately predicted directly from molecular structure using a graph convolutional neural network (GCN) model. Assisted by this strategy, several promising WSAs, including tetrahydropyran, methanol, and acetone, were successfully identified. As a proof of concept, tetrahydropyran was selected as the additive for systematic studies. Remarkably enhanced cycling stability with a lifespan of over 2400 h and low overpotential was demonstrated for the symmetric cell with tetrahydropyran. The proposed data-driven strategy enables the rapid screening of WSAs directly from molecular structures, offering an efficient pathway for the exploration of high-performance electrolyte additives.<\/jats:p>","DOI":"10.1021\/acsnano.6c07571","type":"journal-article","created":{"date-parts":[[2026,8,13]],"date-time":"2026-08-13T12:02:32Z","timestamp":1786622552000},"page":"23367-23380","source":"Crossref","is-referenced-by-count":0,"title":["Data-Driven\nExploration of Weakly Solvating Additives\ntoward the Stabilization of Zn Metal Anodes"],"prefix":"10.1021","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2651-4563","authenticated-orcid":true,"given":"Lin","family":"Hong","sequence":"first","affiliation":[{"name":"Shanghai Jiao Tong University , , 800 Dongchuan Road , ,","place":["Shanghai, China, 200240"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xi","family":"Zhang","sequence":"additional","affiliation":[{"name":"Shanghai Jiao Tong University , , 800 Dongchuan Road , ,","place":["Shanghai, China, 200240"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yichi","family":"Zhang","sequence":"additional","affiliation":[{"name":"Shanghai Jiao Tong University , , 800 Dongchuan Road , ,","place":["Shanghai, China, 200240"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kaicun","family":"Liu","sequence":"additional","affiliation":[{"name":"Shanghai Jiao Tong University , , 800 Dongchuan Road , ,","place":["Shanghai, China, 200240"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0606-549X","authenticated-orcid":true,"given":"Yu-Si","family":"Liu","sequence":"additional","affiliation":[{"name":"Shanghai Jiao Tong University , , 800 Dongchuan Road , ,","place":["Shanghai, China, 200240"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7885-4378","authenticated-orcid":true,"given":"Wei","family":"Huang","sequence":"additional","affiliation":[{"name":"Shanghai Jiao Tong University , , 800 Dongchuan Road , ,","place":["Shanghai, China, 200240"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6282-5882","authenticated-orcid":true,"given":"Yongfeng","family":"Zhou","sequence":"additional","affiliation":[{"name":"Shanghai Jiao Tong University , , 800 Dongchuan Road , ,","place":["Shanghai, China, 200240"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2076-5487","authenticated-orcid":true,"given":"Kai-Xue","family":"Wang","sequence":"additional","affiliation":[{"name":"Shanghai Jiao Tong University , , 800 Dongchuan Road , ,","place":["Shanghai, China, 200240"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2026,8,13]]},"reference":[{"key":"2026083119011393700_cit1","doi-asserted-by":"publisher","first-page":"101802","DOI":"10.1016\/j.joule.2024.12.003","article-title":"Overlooked calendar issues of aqueous zinc metal batteries","volume":"9","author":"Zhang","year":"2024","journal-title":"Joule"},{"issue":"1","key":"2026083119011393700_cit2","doi-asserted-by":"publisher","first-page":"753","DOI":"10.1038\/s41467-024-44893-0","article-title":"An extended\nsubstrate screening strategy enabling a\nlow lattice mismatch for highly reversible zinc anodes","volume":"15","author":"Zheng","year":"2024","journal-title":"Nat. Commun."},{"key":"2026083119011393700_cit3","doi-asserted-by":"publisher","DOI":"10.1002\/adma.202413515","article-title":"Versatile Biopolymers\nfor Advanced Lithium and Zinc Metal Batteries","volume":"37","author":"Li","year":"2025","journal-title":"Adv. Mater."},{"key":"2026083119011393700_cit4","doi-asserted-by":"publisher","DOI":"10.1002\/adma.202413677","article-title":"Reviving Zn Dendrites\nto Electroactive Zn2+ by Ion Sieve\nInterface","volume":"37","author":"Liu","year":"2025","journal-title":"Adv. Mater."},{"issue":"31","key":"2026083119011393700_cit5","doi-asserted-by":"publisher","first-page":"16814","DOI":"10.1039\/D1TA03967A","article-title":"Boosting the Zn-ion transfer kinetics to stabilize\nthe Zn metal interface for high-performance rechargeable Zn-ion batteries","volume":"9","author":"Hong","year":"2021","journal-title":"J. Mater. Chem. 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Mater."},{"key":"2026083119011393700_cit9","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202419394","article-title":"Stimulating the Potential of Zn Anodes to Operate in\nLow pH and Harsh\nEnvironments for Highly Sustainable Zn Batteries","volume":"64","author":"Yang","year":"2025","journal-title":"Angew. Chem., Int. Ed."},{"key":"2026083119011393700_cit10","doi-asserted-by":"publisher","first-page":"982","DOI":"10.1039\/D4EE04870A","article-title":"Highly reversible zinc anode enabled\nby a trace-amount additive with pH buffering capability","volume":"18","author":"Ma","year":"2025","journal-title":"Energy Environ. 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Ed."},{"issue":"5","key":"2026083119011393700_cit26","doi-asserted-by":"publisher","first-page":"6647","DOI":"10.1021\/acsami.2c17714","article-title":"Decreasing\nWater Activity Using the Tetrahydrofuran Electrolyte Additive for\nHighly Reversible Aqueous Zinc Metal Batteries","volume":"15","author":"He","year":"2023","journal-title":"ACS Appl. Mater. Interfaces"},{"issue":"17","key":"2026083119011393700_cit27","doi-asserted-by":"publisher","first-page":"21857","DOI":"10.1021\/acsami.4c01484","article-title":"Ethanol as Solvent Additives with\nCompetitive Effect for High-Stable Aqueous Zinc Batteries","volume":"16","author":"Tian","year":"2024","journal-title":"ACS Appl. Mater. Interfaces"},{"issue":"27","key":"2026083119011393700_cit28","doi-asserted-by":"publisher","DOI":"10.1002\/smll.202202363","article-title":"Achieving Highly Reversible Zinc Anodes via N, N-Dimethylacetamide\nEnabled Zn-Ion Solvation Regulation","volume":"18","author":"Wu","year":"2022","journal-title":"Small"},{"issue":"27","key":"2026083119011393700_cit29","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.202214648","article-title":"Regulating the Water\nMolecular in the Solvation Structure for Stable Zinc Metal Batteries","volume":"33","author":"Zhang","year":"2023","journal-title":"Adv. Funct. Mater."},{"issue":"5","key":"2026083119011393700_cit30","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.202214538","article-title":"A Dual-Functional Organic Electrolyte Additive with\nRegulating Suitable Overpotential for Building Highly Reversible Aqueous\nZinc Ion Batteries","volume":"34","author":"Liu","year":"2024","journal-title":"Adv. Funct. Mater."},{"issue":"6","key":"2026083119011393700_cit31","doi-asserted-by":"publisher","DOI":"10.1002\/smll.202103345","article-title":"Ultrastable Zinc Anode by Simultaneously Manipulating\nSolvation Sheath\nand Inducing Oriented Deposition with PEG Stability Promoter","volume":"18","author":"Cao","year":"2022","journal-title":"Small"},{"key":"2026083119011393700_cit32","doi-asserted-by":"publisher","DOI":"10.1038\/nenergy.2016.39","article-title":"Reversible aqueous zinc\/manganese oxide energy storage from conversion\nreactions","volume":"1","author":"Pan","year":"2016","journal-title":"Nat. Energy"},{"issue":"1","key":"2026083119011393700_cit33","doi-asserted-by":"publisher","first-page":"133","DOI":"10.1021\/acs.jcim.4c01862","article-title":"Automatic Prediction of Molecular\nProperties Using Substructure Vector Embeddings within a Feature Selection\nWorkflow","volume":"65","author":"Jung","year":"2025","journal-title":"J. Chem. Inf. Model."},{"issue":"7715","key":"2026083119011393700_cit34","doi-asserted-by":"publisher","first-page":"547","DOI":"10.1038\/s41586-018-0337-2","article-title":"Machine learning\nfor molecular and materials science","volume":"559","author":"Butler","year":"2018","journal-title":"Nature"}],"container-title":["ACS Nano"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsnano.6c07571","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/ancac3\/article-pdf\/20\/33\/23367\/66523079\/acsnano.6c07571.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/pubs.acs.org\/ancac3\/article-pdf\/20\/33\/23367\/66523079\/acsnano.6c07571.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T23:01:17Z","timestamp":1788217277000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/ancac3\/article\/20\/33\/23367\/5254160\/Data-Driven-Exploration-of-Weakly-Solvating"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8,13]]},"references-count":34,"journal-issue":{"issue":"33","published-online":{"date-parts":[[2026,8,13]]},"published-print":{"date-parts":[[2026,8,25]]}},"URL":"https:\/\/doi.org\/10.1021\/acsnano.6c07571","relation":{},"ISSN":["1936-0851","1936-086X"],"issn-type":[{"value":"1936-0851","type":"print"},{"value":"1936-086X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,8,13]]}}}