{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T14:06:49Z","timestamp":1788876409194,"version":"build-2803163510"},"reference-count":31,"publisher":"American Chemical Society (ACS)","issue":"35","funder":[{"DOI":"10.13039\/100016804","name":"Natural Science Foundation of Shenzhen Municipality","doi-asserted-by":"publisher","award":["GXWD20220817153451002"],"award-info":[{"award-number":["GXWD20220817153451002"]}],"id":[{"id":"10.13039\/100016804","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100016804","name":"Natural Science Foundation of Shenzhen Municipality","doi-asserted-by":"publisher","award":["JCYJ20250604174659001"],"award-info":[{"award-number":["JCYJ20250604174659001"]}],"id":[{"id":"10.13039\/100016804","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003453","name":"Natural Science Foundation of Guangdong Province","doi-asserted-by":"publisher","award":["2021A1515011403"],"award-info":[{"award-number":["2021A1515011403"]}],"id":[{"id":"10.13039\/501100003453","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003453","name":"Natural Science Foundation of Guangdong Province","doi-asserted-by":"publisher","award":["2024A151501170"],"award-info":[{"award-number":["2024A151501170"]}],"id":[{"id":"10.13039\/501100003453","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012226","name":"Fundamental Research Funds for the Central Universities","doi-asserted-by":"publisher","award":["76190-18841290"],"award-info":[{"award-number":["76190-18841290"]}],"id":[{"id":"10.13039\/501100012226","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/na","name":"National Basic Research Program of China","doi-asserted-by":"publisher","award":["2021YFA1400804"],"award-info":[{"award-number":["2021YFA1400804"]}],"id":[{"id":"10.13039\/na","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/na","name":"National Basic Research Program of China","doi-asserted-by":"publisher","award":["2023YFF0714400"],"award-info":[{"award-number":["2023YFF0714400"]}],"id":[{"id":"10.13039\/na","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/na","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["22574178"],"award-info":[{"award-number":["22574178"]}],"id":[{"id":"10.13039\/na","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/na","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["62205382"],"award-info":[{"award-number":["62205382"]}],"id":[{"id":"10.13039\/na","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/na","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["92365112"],"award-info":[{"award-number":["92365112"]}],"id":[{"id":"10.13039\/na","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/na","name":"Guangdong Provincial Quantum Science Strategic Initiative","doi-asserted-by":"publisher","award":["GDZX2305005"],"award-info":[{"award-number":["GDZX2305005"]}],"id":[{"id":"10.13039\/na","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,9,8]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Bacterial contamination in liquid products remains a major challenge for food safety and public health, yet conventional detection methods generally rely on sampling-and-testing workflows that disrupt the original state of sealed containers. This limitation makes it difficult to perform nondestructive, item-level surveillance during transportation, storage, and consumer use. Here, we report a container-integrated plasmonic metasurface interface for camera-readable bacterial surveillance in liquid environments. The metasurface interface can be conformally integrated onto the inner surfaces of transparent containers through a clean nanotransfer lithography process, enabling long-term monitoring of contamination-related changes. Instead of relying on spectral interrogation, bacterial attachment and proliferation processes are converted into spatial transmission image patterns that can be directly acquired using a camera or smartphone. This image-based readout enables in situ monitoring of bacterial proliferation and quantitative detection of Escherichia coli in closed liquid systems. Furthermore, deep image-feature analysis enables label-free grouping of E. coli, Staphylococcus aureus, and their mixed samples with an accuracy of 95%. This work establishes a container-integrated metasurface interface for sampling-free bacterial surveillance, offering a promising route toward nondestructive microbial screening in beverage safety and other closed liquid systems.<\/jats:p>","DOI":"10.1021\/acsnano.6c10863","type":"journal-article","created":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T21:22:08Z","timestamp":1788211328000},"page":"24553-24565","source":"Crossref","is-referenced-by-count":0,"title":["Container-Integrated\nPlasmonic Metasurface Interfaces\nfor Camera-Readable Bacterial Surveillance in Liquid Environments"],"prefix":"10.1021","volume":"20","author":[{"given":"Chenyu","family":"Liao","sequence":"first","affiliation":[{"name":"Shenzhen Campus of Sun Yat-sen University , , ,","place":["Shenzhen, China, 518107"]},{"name":"Sun Yat-sen University , , ,","place":["Guangzhou, China, 510275"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bin","family":"Guan","sequence":"additional","affiliation":[{"name":"Shenzhen Campus of Sun Yat-sen University , , ,","place":["Shenzhen, China, 518107"]},{"name":"Sun Yat-sen University , , ,","place":["Guangzhou, China, 510275"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongjiang","family":"Zhu","sequence":"additional","affiliation":[{"name":"Shenzhen Campus of Sun Yat-sen University , , ,","place":["Shenzhen, China, 518107"]},{"name":"Sun Yat-sen University , , ,","place":["Guangzhou, China, 510275"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3554-1379","authenticated-orcid":true,"given":"Jingxuan","family":"Cai","sequence":"additional","affiliation":[{"name":"Shenzhen Campus of Sun Yat-sen University , , ,","place":["Shenzhen, China, 518107"]},{"name":"Sun Yat-sen University , , ,","place":["Guangzhou, China, 510275"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiangyi","family":"Ye","sequence":"additional","affiliation":[{"name":"Shenzhen Campus of Sun Yat-sen University , , ,","place":["Shenzhen, China, 518107"]},{"name":"Sun Yat-sen University , , ,","place":["Guangzhou, China, 510275"]},{"name":"Chinese Academy of Sciences , , ,","place":["Guangzhou, P. R. China, 510700"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9895-8679","authenticated-orcid":true,"given":"Jianhua","family":"Zhou","sequence":"additional","affiliation":[{"name":"Shenzhen Campus of Sun Yat-sen University , , ,","place":["Shenzhen, China, 518107"]},{"name":"Sun Yat-sen University , , ,","place":["Guangzhou, China, 510275"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2026,8,24]]},"reference":[{"key":"2026090809083576500_cit1","doi-asserted-by":"publisher","first-page":"122","DOI":"10.1016\/j.bios.2018.01.049","article-title":"Engineering\nNanomaterials-Based Biosensors for Food Safety Detection","volume":"106","author":"Lv","year":"2018","journal-title":"Biosens. Bioelectron."},{"key":"2026090809083576500_cit2","doi-asserted-by":"publisher","first-page":"529","DOI":"10.3934\/microbiol.2017.3.529","article-title":"Foodborne\nPathogens","volume":"3","author":"Bintsis","year":"2017","journal-title":"AIMS Microbiol."},{"key":"2026090809083576500_cit3","doi-asserted-by":"publisher","first-page":"377","DOI":"10.3934\/microbiol.2018.3.377","article-title":"Microbial\nPollution and Food Safety","volume":"4","author":"Bintsis","year":"2018","journal-title":"AIMS Microbiol."},{"key":"2026090809083576500_cit4","doi-asserted-by":"publisher","first-page":"29819","DOI":"10.3402\/fnr.v60.29819","article-title":"Public\nHealth Implications of Microbial Food Safety and Foodborne Diseases\nin Developing Countries","volume":"60","author":"Odeyemi","year":"2016","journal-title":"Food Nutr. Res."},{"key":"2026090809083576500_cit5","doi-asserted-by":"publisher","first-page":"380","DOI":"10.1038\/s41579-023-00852-y","article-title":"Staphylococcus\naureus Host Interactions and Adaptation","volume":"21","author":"Howden","year":"2023","journal-title":"Nat.\nRev. Microbiol."},{"key":"2026090809083576500_cit6","doi-asserted-by":"publisher","first-page":"123","DOI":"10.1038\/nrmicro818","article-title":"Pathogenic\nEscherichia coli","volume":"2","author":"Kaper","year":"2004","journal-title":"Nat. Rev. Microbiol."},{"key":"2026090809083576500_cit7","unstructured":"World Health Organization.\n          . Food Safety. https:\/\/www.who.int\/news-room\/fact-sheets\/detail\/food-safety (accessed May 13, 2026)."},{"key":"2026090809083576500_cit8","doi-asserted-by":"publisher","first-page":"131485","DOI":"10.1016\/j.jhazmat.2023.131485","article-title":"Argonaute-Triggered\nVisual and Rebuilding-Free Foodborne Pathogenic\nBacteria Detection","volume":"454","author":"Li","year":"2023","journal-title":"J. Hazard. Mater."},{"key":"2026090809083576500_cit9","doi-asserted-by":"publisher","first-page":"88","DOI":"10.1007\/s40588-018-0094-x","article-title":"Staphylococcus aureus as a Foodborne\nPathogen","volume":"5","author":"Fetsch","year":"2018","journal-title":"Curr. Clin. Microbiol. Rep."},{"key":"2026090809083576500_cit10","doi-asserted-by":"publisher","first-page":"1840","DOI":"10.3201\/eid1312.070629","article-title":"Hospitalizations\nand Deaths Caused\nby Methicillin-Resistant Staphylococcus aureus, United States, 1999\u20132005","volume":"13","author":"Klein","year":"2007","journal-title":"Emerg. Infect. Dis."},{"key":"2026090809083576500_cit11","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0072788","article-title":"Global Causes of Diarrheal Disease Mortality in Children\n&lt; 5 Years of Age: A Systematic Review","volume":"8","author":"Lanata","year":"2013","journal-title":"PLoS\nOne"},{"key":"2026090809083576500_cit12","doi-asserted-by":"publisher","first-page":"1229","DOI":"10.1016\/S1473-3099(18)30475-4","article-title":"Morbidity\nand Mortality Due to Shigella and Enterotoxigenic Escherichia coli\nDiarrhoea: The Global Burden of Disease Study 1990\u20132016","volume":"18","author":"Khalil","year":"2018","journal-title":"Lancet Infect. Dis."},{"key":"2026090809083576500_cit13","doi-asserted-by":"publisher","first-page":"49","DOI":"10.1016\/j.bios.2018.01.023","article-title":"Biosensors for Rapid\nand Sensitive Detection of Staphylococcus aureus in Food","volume":"105","author":"Rubab","year":"2018","journal-title":"Biosens. Bioelectron."},{"key":"2026090809083576500_cit14","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1007\/978-3-319-08057-4_2","article-title":"Survival of Microorganisms\non Inanimate Surfaces","volume-title":"Use of Biocidal\nSurfaces for Reduction of Healthcare Acquired Infections","author":"Kramer","year":"2014"},{"key":"2026090809083576500_cit15","doi-asserted-by":"publisher","first-page":"128697","DOI":"10.1155\/2015\/128697","article-title":"Health Safety\nof Soft Drinks: Contents, Containers, and Microorganisms","volume":"2015","author":"Kregiel","year":"2015","journal-title":"BioMed Res. Int."},{"key":"2026090809083576500_cit16","doi-asserted-by":"publisher","first-page":"781","DOI":"10.1080\/10934529.2013.744647","article-title":"Microbial\nContamination Associated with Consumption and the Growth in Plastic\nBottled Beverage","volume":"48","author":"Ohnishi","year":"2013","journal-title":"J. Environ. Sci. Health Part\nA:Environ. Sci. Eng. Toxic Hazard. Subst. Control"},{"key":"2026090809083576500_cit17","unstructured":"China National Center for Food Safety Risk Assessment.\n          . National\nFood Safety Standard Database. https:\/\/sppt.cfsa.net.cn:8086\/db?type=2&guid=459B054F-EAA7-4729-9889-5402BCFFCB3C (accessed May 24, 2026)."},{"key":"2026090809083576500_cit18","doi-asserted-by":"publisher","first-page":"2211363","DOI":"10.1002\/adma.202211363","article-title":"Rapid Identification and Monitoring of Multiple\nBacterial Infections Using Printed Nanoarrays","volume":"35","author":"Zhang","year":"2023","journal-title":"Adv. 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Commun."},{"key":"2026090809083576500_cit22","doi-asserted-by":"publisher","first-page":"283","DOI":"10.1038\/s41467-025-66996-y","article-title":"Rapid Culture-Free Diagnosis of Clinical Pathogens via Integrated\nMicrofluidic-Raman Micro-Spectroscopy","volume":"17","author":"Li","year":"2026","journal-title":"Nat.\nCommun."},{"key":"2026090809083576500_cit23","doi-asserted-by":"publisher","first-page":"3470","DOI":"10.1038\/s41467-022-31137-2","article-title":"Terahertz Thermal\nCurve Analysis for Label-Free Identification\nof Pathogens","volume":"13","author":"Jun","year":"2022","journal-title":"Nat. Commun."},{"key":"2026090809083576500_cit24","doi-asserted-by":"publisher","first-page":"118","DOI":"10.1038\/s41377-020-00358-9","article-title":"Early Detection and Classification\nof Live Bacteria Using Time-Lapse Coherent Imaging and Deep Learning","volume":"9","author":"Wang","year":"2020","journal-title":"Light Sci. Appl."},{"key":"2026090809083576500_cit25","doi-asserted-by":"publisher","first-page":"8","DOI":"10.1038\/s44328-024-00008-9","article-title":"Realtime Bacteria Detection\nand Analysis\nin Sterile Liquid Products Using Deep Learning Holographic Imaging","volume":"1","author":"Bravo-Frank","year":"2024","journal-title":"npj Biosens."},{"key":"2026090809083576500_cit26","doi-asserted-by":"publisher","first-page":"215","DOI":"10.1586\/17434440.3.2.215","article-title":"Raman Microspectroscopy:\nA Noninvasive Tool for Studies\nof Individual Living Cells in Vitro","volume":"3","author":"Notingher","year":"2006","journal-title":"Expert\nRev. Med. Devices"},{"key":"2026090809083576500_cit27","doi-asserted-by":"publisher","first-page":"1031","DOI":"10.1038\/s41566-023-01299-6","article-title":"Label-Free Biomedical\nOptical Imaging","volume":"17","author":"Shaked","year":"2023","journal-title":"Nat. Photonics"},{"key":"2026090809083576500_cit28","doi-asserted-by":"publisher","first-page":"8","DOI":"10.1038\/s41378-022-00476-x","article-title":"High-Fidelity\nand Clean Nanotransfer Lithography Using Structure-Embedded and Electrostatic-Adhesive\nCarriers","volume":"9","author":"Gan","year":"2023","journal-title":"Microsyst. Nanoeng."},{"key":"2026090809083576500_cit29","doi-asserted-by":"publisher","first-page":"372","DOI":"10.1016\/j.ijbiomac.2009.07.006","article-title":"Physicochemical\nand Bioactivity of\nCross-Linked Chitosan\u2013PVA Film for Food Packaging Applications","volume":"45","author":"Tripathi","year":"2009","journal-title":"Int. J. Biol. Macromol."},{"key":"2026090809083576500_cit30","doi-asserted-by":"publisher","first-page":"2100270","DOI":"10.1002\/adma.202100270","article-title":"Ultrasensitive\nMolecular Detection by Imaging of Centimeter-Scale Metasurfaces with\na Deterministic Gradient Geometry","volume":"33","author":"Min","year":"2021","journal-title":"Adv. Mater."},{"key":"2026090809083576500_cit31","doi-asserted-by":"publisher","first-page":"2300873","DOI":"10.1002\/smtd.202300873","article-title":"Cost-Effective Nanophotonic\nMetasurfaces with Spatially Gradient Structures for Ultrasensitive\nImaging-Based Refractometric Sensing","volume":"8","author":"Li","year":"2024","journal-title":"Small\nMethods"}],"container-title":["ACS Nano"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/ancac3\/article-pdf\/20\/35\/24553\/67392547\/acsnano.6c10863.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/pubs.acs.org\/ancac3\/article-pdf\/20\/35\/24553\/67392547\/acsnano.6c10863.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T13:08:49Z","timestamp":1788872929000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/ancac3\/article\/20\/35\/24553\/5328204\/Container-Integrated-Plasmonic-Metasurface"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8,24]]},"references-count":31,"journal-issue":{"issue":"35","published-online":{"date-parts":[[2026,8,24]]},"published-print":{"date-parts":[[2026,9,8]]}},"URL":"https:\/\/doi.org\/10.1021\/acsnano.6c10863","relation":{},"ISSN":["1936-0851","1936-086X"],"issn-type":[{"value":"1936-0851","type":"print"},{"value":"1936-086X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,8,24]]}}}