{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T15:52:45Z","timestamp":1789487565119,"version":"build-2803163510"},"reference-count":35,"publisher":"American Chemical Society (ACS)","issue":"36","license":[{"start":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T00:00:00Z","timestamp":1787875200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T00:00:00Z","timestamp":1787875200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T00:00:00Z","timestamp":1787875200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["52373139"],"award-info":[{"award-number":["52373139"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["52503156"],"award-info":[{"award-number":["52503156"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["U2436202"],"award-info":[{"award-number":["U2436202"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Guangdong Basic and Applied Basic Research Foundation","award":["2024A1515240042"],"award-info":[{"award-number":["2024A1515240042"]}]},{"name":"Guangdong Basic and Applied Basic Research Foundation","award":["2025A0505020003"],"award-info":[{"award-number":["2025A0505020003"]}]},{"name":"Basic Research Program of Shenzhen","award":["JCYJ20230807093419041"],"award-info":[{"award-number":["JCYJ20230807093419041"]}]},{"name":"Basic Research Program of Shenzhen","award":["JCYJ20240813094159001"],"award-info":[{"award-number":["JCYJ20240813094159001"]}]},{"name":"Brain Science and Brain-like Intelligence Technology-National Science and Technology Major Project","award":["2022ZD0209500"],"award-info":[{"award-number":["2022ZD0209500"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,9,15]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Stable bioelectronic coupling in mechanically active tissues remains challenging because conventional interfaces rely on static architectures that cannot dissipate deformation-induced interfacial stress, resulting in progressive contact failure and signal instability. Here, we report an injectable magnetoelectric hydrogel that forms a dynamic conformal neural electroactive tissue-biointerface (DyCONNECT) with deformable neural tissues. By integrating polydopamine-modified magnetoelectric nanoparticles within a dynamically adaptive conductive network, DyCONNECT combines tissue adhesion, electrical conductivity, structural recoverability, and wireless electroactive regulation. The dynamic network enables continuous stress relaxation and interfacial reconfiguration, allowing DyCONNECT to preserve conformal tissue contact, suppress deformation-induced damage accumulation, and maintain low-impedance electrical coupling under cyclic mechanical loading. Upon pulsed magnetic stimulation, DyCONNECT generates localized electrical cues that enhance neural-related cellular activities and evoke remote electrophysiological responses. In a rat spinal cord injury model, DyCONNECT facilitates neuronal preservation, axonal regeneration, and sensorimotor functional recovery. These results demonstrate that dynamic interfacial adaptation can preserve bioelectronic coupling under physiological deformation and support electroactive neural repair in mechanically active tissues.<\/jats:p>","DOI":"10.1021\/acsnano.6c12948","type":"journal-article","created":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T02:07:28Z","timestamp":1788314848000},"page":"25150-25161","source":"Crossref","is-referenced-by-count":0,"title":["Dynamic\nConformal Neural Electroactive Biointerfacing\nSustains Bioelectronic Coupling for Spinal Cord Repair"],"prefix":"10.1021","volume":"20","author":[{"given":"Pujing","family":"Shi","sequence":"first","affiliation":[{"name":"Southern University of Science and Technology , , ,","place":["Shenzhen, P. R. China, 518055"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhipeng","family":"Ni","sequence":"additional","affiliation":[{"name":"Southern University of Science and Technology , , ,","place":["Shenzhen, P. R. China, 518055"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yifan","family":"Yang","sequence":"additional","affiliation":[{"name":"Southern University of Science and Technology , , ,","place":["Shenzhen, P. R. China, 518055"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yafei","family":"Wang","sequence":"additional","affiliation":[{"name":"Southern University of Science and Technology , , ,","place":["Shenzhen, P. R. China, 518055"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lingfeng","family":"Yuan","sequence":"additional","affiliation":[{"name":"Southern University of Science and Technology , , ,","place":["Shenzhen, P. R. China, 518055"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liangjie","family":"Shan","sequence":"additional","affiliation":[{"name":"Southern University of Science and Technology , , ,","place":["Shenzhen, P. R. China, 518055"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shenglong","family":"Zhu","sequence":"additional","affiliation":[{"name":"Southern University of Science and Technology , , ,","place":["Shenzhen, P. R. China, 518055"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4543-1886","authenticated-orcid":true,"given":"Boyuan","family":"Huang","sequence":"additional","affiliation":[{"name":"Southern University of Science and Technology , , ,","place":["Shenzhen, P. R. China, 518055"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7171-405X","authenticated-orcid":true,"given":"Ji","family":"Liu","sequence":"additional","affiliation":[{"name":"Southern University of Science and Technology , , ,","place":["Shenzhen, P. R. China, 518055"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2026,8,28]]},"reference":[{"issue":"45","key":"2026091510110206200_cit1","doi-asserted-by":"publisher","DOI":"10.1126\/sciadv.adz3668","article-title":"Adhesive nonfibrotic\nbioelectronic interfaces on diverse peripheral nerves for long-term\nfunctional neuromodulation","volume":"11","author":"Moon","year":"2025","journal-title":"Sci. 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Mater."},{"issue":"25","key":"2026091510110206200_cit5","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.202422869","article-title":"Conducting Hydrogel-Based Neural Biointerfacing Technologies","volume":"35","author":"Zhang","year":"2025","journal-title":"Adv. Funct. Mater."},{"issue":"7","key":"2026091510110206200_cit6","doi-asserted-by":"publisher","first-page":"969","DOI":"10.1038\/s41563-024-01886-0","article-title":"Electrochemically actuated microelectrodes for minimally invasive\nperipheral nerve interfaces","volume":"23","author":"Dong","year":"2024","journal-title":"Nat. Mater."},{"issue":"2","key":"2026091510110206200_cit7","doi-asserted-by":"publisher","DOI":"10.1002\/adma.202511014","article-title":"Mechanically\nCompliant and Impedance Matching Hydrogel Bioelectronics\nfor Low-Voltage Peripheral Neuromodulation","volume":"38","author":"Shan","year":"2026","journal-title":"Adv. Mater."},{"issue":"9","key":"2026091510110206200_cit8","doi-asserted-by":"publisher","first-page":"1031","DOI":"10.1038\/s41587-020-0495-2","article-title":"Morphing\nelectronics enable neuromodulation in growing tissue","volume":"38","author":"Liu","year":"2020","journal-title":"Nat. Biotechnol."},{"issue":"1","key":"2026091510110206200_cit9","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-020-18025-3","article-title":"Adaptive\nself-healing electronic epineurium for chronic bidirectional neural\ninterfaces","volume":"11","author":"Song","year":"2020","journal-title":"Nat. Commun."},{"issue":"1","key":"2026091510110206200_cit10","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-024-52418-y","article-title":"Highly-stable, injectable,\nconductive hydrogel for chronic neuromodulation","volume":"15","author":"Yang","year":"2024","journal-title":"Nat. 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Mater."},{"issue":"1","key":"2026091510110206200_cit14","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-023-37948-1","article-title":"Highly conductive tissue-like\nhydrogel interface through template-directed assembly","volume":"14","author":"Chong","year":"2023","journal-title":"Nat. Commun."},{"issue":"19","key":"2026091510110206200_cit15","doi-asserted-by":"publisher","DOI":"10.1126\/sciadv.abd3716","article-title":"Tissue-like skin-device interface for wearable bioelectronics\nby using ultrasoft, mass-permeable, and low-impedance hydrogels","volume":"7","author":"Lim","year":"2021","journal-title":"Sci. Adv."},{"issue":"1","key":"2026091510110206200_cit16","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-023-40004-7","article-title":"Liquid-in-liquid\nprinting of 3D and mechanically tunable conductive hydrogels","volume":"14","author":"Xie","year":"2023","journal-title":"Nat. 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Electron."},{"issue":"6801","key":"2026091510110206200_cit27","doi-asserted-by":"publisher","DOI":"10.1126\/science.aed1630","article-title":"Strain-resilient\nintrinsically stretchable electrochemical biointerfaces","volume":"392","author":"Xu","year":"2026","journal-title":"Science"},{"key":"2026091510110206200_cit28","doi-asserted-by":"publisher","DOI":"10.1002\/adma.72866","article-title":"Conductive Hydrogels\nfor Exogenous Sensing and Cell Fate Control","volume":"38","author":"Akbar","year":"2026","journal-title":"Adv. Mater."},{"issue":"27","key":"2026091510110206200_cit29","doi-asserted-by":"publisher","DOI":"10.1002\/adma.73074","article-title":"Phase-Transition-Driven\nAdaptive Reconfiguration of Wearable Devices for Conformal Biointerfaces","volume":"38","author":"Hu","year":"2026","journal-title":"Adv. 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Biomed.\nEng."},{"issue":"21","key":"2026091510110206200_cit35","doi-asserted-by":"publisher","DOI":"10.1002\/adma.202313672","article-title":"Multifunctional\nconductive and electrogenic hydrogel repaired spinal\ncord injury via immunoregulation and enhancement of neuronal differentiation","volume":"36","author":"Liu","year":"2024","journal-title":"Adv. Mater."}],"container-title":["ACS Nano"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsnano.6c12948","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/ancac3\/article-pdf\/20\/36\/25150\/67583246\/acsnano.6c12948.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/pubs.acs.org\/ancac3\/article-pdf\/20\/36\/25150\/67583246\/acsnano.6c12948.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T14:50:46Z","timestamp":1789483846000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/ancac3\/article\/20\/36\/25150\/5347211\/Dynamic-Conformal-Neural-Electroactive"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8,28]]},"references-count":35,"journal-issue":{"issue":"36","published-online":{"date-parts":[[2026,8,28]]},"published-print":{"date-parts":[[2026,9,15]]}},"URL":"https:\/\/doi.org\/10.1021\/acsnano.6c12948","relation":{},"ISSN":["1936-0851","1936-086X"],"issn-type":[{"value":"1936-0851","type":"print"},{"value":"1936-086X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,8,28]]}}}