{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,7]],"date-time":"2026-03-07T13:25:45Z","timestamp":1772889945243,"version":"3.50.1"},"reference-count":42,"publisher":"American Chemical Society (ACS)","issue":"10","license":[{"start":{"date-parts":[[2019,9,9]],"date-time":"2019-09-09T00:00:00Z","timestamp":1567987200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2019,9,9]],"date-time":"2019-09-09T00:00:00Z","timestamp":1567987200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2019,9,9]],"date-time":"2019-09-09T00:00:00Z","timestamp":1567987200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/100007270","name":"University of Michigan","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007270","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000054","name":"National Cancer Institute","doi-asserted-by":"publisher","award":["R01CA210273"],"award-info":[{"award-number":["R01CA210273"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000054","name":"National Cancer Institute","doi-asserted-by":"publisher","award":["U01CA210152"],"award-info":[{"award-number":["U01CA210152"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000054","name":"National Cancer Institute","doi-asserted-by":"publisher","award":["R01CA223804"],"award-info":[{"award-number":["R01CA223804"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100005190","name":"Melanoma Research Alliance","doi-asserted-by":"publisher","award":["348774"],"award-info":[{"award-number":["348774"]}],"id":[{"id":"10.13039\/100005190","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000060","name":"National Institute of Allergy and Infectious Diseases","doi-asserted-by":"publisher","award":["R01AI127070"],"award-info":[{"award-number":["R01AI127070"]}],"id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000070","name":"National Institute of Biomedical Imaging and Bioengineering","doi-asserted-by":"publisher","award":["R01EB022563"],"award-info":[{"award-number":["R01EB022563"]}],"id":[{"id":"10.13039\/100000070","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000005","name":"U.S. Department of Defense","doi-asserted-by":"publisher","award":["W81XWH-16-1-0369"],"award-info":[{"award-number":["W81XWH-16-1-0369"]}],"id":[{"id":"10.13039\/100000005","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000774","name":"Defense Threat Reduction Agency","doi-asserted-by":"publisher","award":["DTRACB3947"],"award-info":[{"award-number":["DTRACB3947"]}],"id":[{"id":"10.13039\/100000774","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000146","name":"Division of Chemical, Bioengineering, Environmental, and Transport Systems","doi-asserted-by":"publisher","award":["1553831"],"award-info":[{"award-number":["1553831"]}],"id":[{"id":"10.13039\/100000146","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100014894","name":"Emerald Foundation","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100014894","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ACS Nano"],"published-print":{"date-parts":[[2019,10,22]]},"DOI":"10.1021\/acsnano.9b03660","type":"journal-article","created":{"date-parts":[[2019,9,9]],"date-time":"2019-09-09T14:49:13Z","timestamp":1568040553000},"page":"11087-11096","source":"Crossref","is-referenced-by-count":37,"title":["Multilamellar Vaccine Particle Elicits Potent Immune Activation with Protein Antigens and Protects Mice against Ebola Virus Infection"],"prefix":"10.1021","volume":"13","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7868-2919","authenticated-orcid":true,"given":"Yuchen","family":"Fan","sequence":"first","affiliation":[{"name":"Department of Pharmaceutical Sciences, University of Michigan, Ann Arbor, Michigan 48109, United States"},{"name":"Biointerfaces Institute, University of Michigan, Ann Arbor, Michigan 48109, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sabrina M.","family":"Stronsky","sequence":"additional","affiliation":[{"name":"Molecular and Translational Sciences, United States Army Medical Research Institute of Infectious Diseases (USAMRIID), Fort Detrick, Maryland 21702, United States"},{"name":"Joint Program Executive Office - Chemical, Biological, Radiological, and Nuclear Defense (JPEO\u2212CBRND), Fort Detrick, Maryland 21702, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yao","family":"Xu","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Sciences, University of Michigan, Ann Arbor, Michigan 48109, United States"},{"name":"Biointerfaces Institute, University of Michigan, Ann Arbor, Michigan 48109, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jesse T.","family":"Steffens","sequence":"additional","affiliation":[{"name":"Molecular and Translational Sciences, United States Army Medical Research Institute of Infectious Diseases (USAMRIID), Fort Detrick, Maryland 21702, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sean A.","family":"van Tongeren","sequence":"additional","affiliation":[{"name":"Molecular and Translational Sciences, United States Army Medical Research Institute of Infectious Diseases (USAMRIID), Fort Detrick, Maryland 21702, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amanda","family":"Erwin","sequence":"additional","affiliation":[{"name":"Department of Cell and Developmental Biology, University of Michigan, Ann Arbor, Michigan 48109, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christopher L.","family":"Cooper","sequence":"additional","affiliation":[{"name":"Molecular and Translational Sciences, United States Army Medical Research Institute of Infectious Diseases (USAMRIID), Fort Detrick, Maryland 21702, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2238-2372","authenticated-orcid":true,"given":"James J.","family":"Moon","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Sciences, University of Michigan, Ann Arbor, Michigan 48109, United States"},{"name":"Biointerfaces Institute, University of Michigan, Ann Arbor, Michigan 48109, United States"},{"name":"Department of Biomedical Engineering, University of Michigan, Ann Arbor, Michigan 48109, United States"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"316","published-online":{"date-parts":[[2019,9,9]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1016\/S2214-109X(15)00092-3"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(16)30332-2"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1038\/nrmicro2872"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(16)32621-6"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1502924"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1414216"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.3390\/vaccines2030624"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1099\/jgv.0.001085"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2019.01.069"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1021\/acs.chemrev.5b00109"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.3390\/vaccines3030662"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1002\/wnan.1403"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1038\/nmat2960"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1112648109"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1126\/scitranslmed.3006516"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1016\/j.nano.2018.11.005"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1021\/acs.nanolett.8b03601"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2015.04.010"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1055\/s-0029-1220647"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1189\/jlb.1012501"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.4161\/onci.20931"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1186\/s12014-016-9119-8"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1002\/biot.201700627"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2016.02.033"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1089\/vim.2014.0071"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1529\/biophysj.104.040360"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1016\/j.virol.2010.02.029"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1126\/science.287.5458.1664"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1016\/j.it.2016.10.003"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-immunol-032712-095910"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.2147\/IJN.S125866"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2011.01.113"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0162446"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2017.01.068"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1209591110"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1016\/j.ebiom.2015.11.041"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1155\/2011\/984241"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1126\/scitranslmed.3004582"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.1038\/emi.2017.31"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.1021\/acs.nanolett.7b03218"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-1759(98)00204-X"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.3791\/52771"}],"container-title":["ACS Nano"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsnano.9b03660","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,18]],"date-time":"2023-04-18T04:16:24Z","timestamp":1681791384000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acsnano.9b03660"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,9,9]]},"references-count":42,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2019,10,22]]}},"alternative-id":["10.1021\/acsnano.9b03660"],"URL":"https:\/\/doi.org\/10.1021\/acsnano.9b03660","relation":{},"ISSN":["1936-0851","1936-086X"],"issn-type":[{"value":"1936-0851","type":"print"},{"value":"1936-086X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,9,9]]}}}