{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T22:27:34Z","timestamp":1787005654572,"version":"build-2736575974"},"reference-count":72,"publisher":"American Chemical Society (ACS)","issue":"4","license":[{"start":{"date-parts":[[2020,3,30]],"date-time":"2020-03-30T00:00:00Z","timestamp":1585526400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2020,3,30]],"date-time":"2020-03-30T00:00:00Z","timestamp":1585526400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2020,3,30]],"date-time":"2020-03-30T00:00:00Z","timestamp":1585526400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/100000005","name":"U.S. Department of Defense","doi-asserted-by":"publisher","award":["W81XWH-16-1-0286"],"award-info":[{"award-number":["W81XWH-16-1-0286"]}],"id":[{"id":"10.13039\/100000005","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Sitemen Investment Program"},{"name":"Alvin J. Siteman Cancer Research Fund","award":["11-FY16-01"],"award-info":[{"award-number":["11-FY16-01"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,4,28]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Rapid liver and spleen opsonization of systemically administered nanoparticles (NPs) for in vivo applications remains the Achilles\u2019 heel of nanomedicine, allowing only a small fraction of the materials to reach the intended target tissue. Although focusing on diseases that reside in the natural disposal organs for nanoparticles is a viable option, it limits the plurality of lesions that could benefit from nanomedical interventions. Here we designed a theranostic nanoplatform consisting of reactive oxygen (ROS)-generating titanium dioxide (TiO2) NPs, coated with a tumor-targeting agent, transferrin (Tf), and radiolabeled with a radionuclide (89Zr) for targeting bone marrow, imaging the distribution of the NPs, and stimulating ROS generation for cell killing. Radiolabeling of TiO2 NPs with 89Zr afforded thermodynamically and kinetically stable chelate-free 89Zr-TiO2-Tf NPs without altering the NP morphology. Treatment of multiple myeloma (MM) cells, a disease of plasma cells originating in the bone marrow, with 89Zr-TiO2-Tf generated cytotoxic ROS to induce cancer cell killing via the apoptosis pathway. Positron emission tomography\/X-ray computed tomography (PET\/CT) imaging and tissue biodistribution studies revealed that in vivo administration of 89Zr-TiO2-Tf in mice leveraged the osteotropic effect of 89Zr to selectively localize about 70% of the injected radioactivity in mouse bone tissue. A combination of small-animal PET\/CT imaging of NP distribution and bioluminescence imaging of cancer progression showed that a single-dose 89Zr-TiO2-Tf treatment in a disseminated MM mouse model completely inhibited cancer growth at euthanasia of untreated mice and at least doubled the survival of treated mice. Treatment of the mice with cold Zr-TiO2-Tf, 89Zr-oxalate, or 89Zr-Tf had no therapeutic benefit compared to untreated controls. This study reveals an effective radionuclide sensitizing nanophototherapy paradigm for the treatment of MM and possibly other bone-associated malignancies.<\/jats:p>","DOI":"10.1021\/acsnano.9b09618","type":"journal-article","created":{"date-parts":[[2020,3,30]],"date-time":"2020-03-30T16:53:15Z","timestamp":1585587195000},"page":"4255-4264","source":"Crossref","is-referenced-by-count":38,"title":["Osteotropic\nRadiolabeled Nanophotosensitizer for Imaging\nand Treating Multiple Myeloma"],"prefix":"10.1021","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2734-1003","authenticated-orcid":true,"given":"Rui","family":"Tang","sequence":"first","affiliation":[{"name":"Washington University School of Medicine , , , ,","place":["St. Louis, Missouri, United States, 63110"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander","family":"Zheleznyak","sequence":"additional","affiliation":[{"name":"Washington University School of Medicine , , , ,","place":["St. Louis, Missouri, United States, 63110"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew","family":"Mixdorf","sequence":"additional","affiliation":[{"name":"Washington University School of Medicine , , , ,","place":["St. Louis, Missouri, United States, 63110"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anchal","family":"Ghai","sequence":"additional","affiliation":[{"name":"Washington University School of Medicine , , , ,","place":["St. Louis, Missouri, United States, 63110"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Julie","family":"Prior","sequence":"additional","affiliation":[{"name":"Washington University School of Medicine , , , ,","place":["St. Louis, Missouri, United States, 63110"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kvar C. L.","family":"Black","sequence":"additional","affiliation":[{"name":"Washington University School of Medicine , , , ,","place":["St. Louis, Missouri, United States, 63110"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Monica","family":"Shokeen","sequence":"additional","affiliation":[{"name":"Washington University School of Medicine , , , ,","place":["St. Louis, Missouri, United States, 63110"]},{"name":"Washington University in St. Louis , , , ,","place":["St. Louis, Missouri, United\nStates, 63105"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nathan","family":"Reed","sequence":"additional","affiliation":[{"name":"Washington University in St. Louis , , , ,","place":["St. Louis, Missouri, United States, 63112"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1104-3738","authenticated-orcid":true,"given":"Pratim","family":"Biswas","sequence":"additional","affiliation":[{"name":"Washington University in St. Louis , , , ,","place":["St. Louis, Missouri, United States, 63112"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3133-6717","authenticated-orcid":true,"given":"Samuel","family":"Achilefu","sequence":"additional","affiliation":[{"name":"Washington University School of Medicine , , , ,","place":["St. Louis, Missouri, United States, 63110"]},{"name":"Washington University in St. Louis , , , ,","place":["St. Louis, Missouri, United\nStates, 63105"]},{"name":"Washington University School of Medicine , , , ,","place":["St. Louis, Missouri, United States, 63110"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2020,3,30]]},"reference":[{"key":"2026081718164492500_cit1","doi-asserted-by":"publisher","first-page":"4806","DOI":"10.1002\/smll.201500802","article-title":"Metal-Organic Framework-Based\nNanomedicine Platforms for Drug Delivery and Molecular Imaging","volume":"11","author":"Cai","year":"2015","journal-title":"Small"},{"key":"2026081718164492500_cit2","doi-asserted-by":"publisher","first-page":"1778","DOI":"10.2967\/jnumed.116.172775","article-title":"Precision Nanomedicine\nUsing Dual PET and MR Temperature Imaging-Guided Photothermal Therapy","volume":"57","author":"Zhou","year":"2016","journal-title":"J. Nucl. Med."},{"key":"2026081718164492500_cit3","doi-asserted-by":"publisher","first-page":"23","DOI":"10.1016\/j.jconrel.2017.06.011","article-title":"Molecular Imaging in Nanomedicine\n- A Developmental\nTool and a Clinical Necessity","volume":"261","author":"Dearling","year":"2017","journal-title":"J. Controlled\nRelease"},{"key":"2026081718164492500_cit4","doi-asserted-by":"publisher","first-page":"339","DOI":"10.20892\/j.issn.2095-3941.2016.0055","article-title":"Multimodality Imaging\nin Nanomedicine and Nanotheranostics","volume":"13","author":"Li","year":"2016","journal-title":"Cancer\nBiol. Med."},{"key":"2026081718164492500_cit5","doi-asserted-by":"publisher","first-page":"2885","DOI":"10.1039\/c2cs15260f","article-title":"The Unique Role of Nanoparticles in Nanomedicine: Imaging, Drug Delivery\nand Therapy","volume":"41","author":"Doane","year":"2012","journal-title":"Chem. Soc. Rev."},{"key":"2026081718164492500_cit6","doi-asserted-by":"publisher","first-page":"1102","DOI":"10.3390\/ijms18051102","article-title":"Nanoparticles\nas Theranostic Vehicles in Experimental and Clinical Applications-Focus\non Prostate and Breast Cancer","volume":"18","author":"Elgqvist","year":"2017","journal-title":"Int. J. Mol.\nSci."},{"key":"2026081718164492500_cit7","doi-asserted-by":"publisher","first-page":"1700306","DOI":"10.1002\/adhm.201700306","article-title":"Synthesis, Functionalization, and\nDesign of Magnetic Nanoparticles for Theranostic Applications","volume":"6","author":"Mosayebi","year":"2017","journal-title":"Adv. Healthcare Mater."},{"key":"2026081718164492500_cit8","doi-asserted-by":"publisher","first-page":"281","DOI":"10.1177\/2472630317738699","article-title":"Theranostic Nanoparticles for Tracking and Monitoring\nDisease State","volume":"23","author":"Zavaleta","year":"2018","journal-title":"SLAS Technol."},{"key":"2026081718164492500_cit9","doi-asserted-by":"publisher","first-page":"8838","DOI":"10.1021\/acsnano.7b03003","article-title":"Transformative Nanomedicine\nof an Amphiphilic Camptothecin Prodrug\nfor Long Circulation and High Tumor Uptake in Cancer Therapy","volume":"11","author":"Zhang","year":"2017","journal-title":"ACS Nano"},{"key":"2026081718164492500_cit10","doi-asserted-by":"publisher","first-page":"82","DOI":"10.1016\/j.addr.2017.06.004","article-title":"Nanomedicine-Based Combination Anticancer\nTherapy between Nucleic Acids and Small-Molecular Drugs","volume":"115","author":"Huang","year":"2017","journal-title":"Adv. Drug Delivery Rev."},{"key":"2026081718164492500_cit11","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1016\/j.addr.2015.10.019","article-title":"\u2033Combo\u2033\nNanomedicine: Co-Delivery of Multi-Modal Therapeutics for Efficient,\nTargeted, and Safe Cancer Therapy","volume":"98","author":"Kemp","year":"2016","journal-title":"Adv. Drug\nDelivery Rev."},{"key":"2026081718164492500_cit12","doi-asserted-by":"publisher","first-page":"7460","DOI":"10.1002\/anie.201602525","article-title":"Bilirubin\nNanoparticles as a Nanomedicine for Anti-Inflammation Therapy","volume":"55","author":"Lee","year":"2016","journal-title":"Angew. Chem., Int. Ed."},{"key":"2026081718164492500_cit13","doi-asserted-by":"publisher","first-page":"299","DOI":"10.1038\/nnano.2015.63","article-title":"Cancer Nanomedicine:\nTherapy from Within","volume":"10","author":"Grimm","year":"2015","journal-title":"Nat. Nanotechnol."},{"key":"2026081718164492500_cit14","doi-asserted-by":"publisher","first-page":"921","DOI":"10.1038\/nnano.2016.199","article-title":"Nanomedicine: An\nIron Age for Cancer Therapy","volume":"11","author":"Tarangelo","year":"2016","journal-title":"Nat. Nanotechnol."},{"key":"2026081718164492500_cit15","doi-asserted-by":"publisher","first-page":"3637","DOI":"10.1039\/C7NR00231A","article-title":"MRI-Guided\nand Ultrasound-Triggered Release of NO by Advanced Nanomedicine","volume":"9","author":"Jin","year":"2017","journal-title":"Nanoscale"},{"key":"2026081718164492500_cit16","doi-asserted-by":"publisher","first-page":"5550","DOI":"10.1002\/adma.201305617","article-title":"Controlled-Release\nSystems for Metal-Based Nanomedicine: Encapsulated\/Self-Assembled\nNanoparticles of Anticancer Gold\u00ad(Iii)\/Platinum\u00ad(Ii) Complexes and Antimicrobial\nSilver Nanoparticles","volume":"26","author":"Lok","year":"2014","journal-title":"Adv. Mater."},{"key":"2026081718164492500_cit17","doi-asserted-by":"publisher","first-page":"419","DOI":"10.1021\/nn4046024","article-title":"Sustained\nDrug Release in Nanomedicine: A Long-Acting Nanocarrier-Based Formulation\nfor Glaucoma","volume":"8","author":"Natarajan","year":"2014","journal-title":"ACS Nano"},{"key":"2026081718164492500_cit18","doi-asserted-by":"publisher","first-page":"14258","DOI":"10.1038\/srep14258","article-title":"NIR-Driven\nSmart Theranostic Nanomedicine for On-Demand Drug Release and Synergistic\nAntitumour Therapy","volume":"5","author":"Zhao","year":"2015","journal-title":"Sci. Rep."},{"key":"2026081718164492500_cit19","doi-asserted-by":"publisher","first-page":"252","DOI":"10.1021\/nn303955n","article-title":"Noninvasive Optical Imaging of Nanomedicine\nBiodistribution","volume":"7","author":"Kunjachan","year":"2013","journal-title":"ACS Nano"},{"key":"2026081718164492500_cit20","doi-asserted-by":"publisher","first-page":"467","DOI":"10.1038\/nnano.2007.234","article-title":"Nanomedicine:\nMagnetic Nanoparticles Hit the Target","volume":"2","author":"Amirfazli","year":"2007","journal-title":"Nat.\nNanotechnol."},{"key":"2026081718164492500_cit21","doi-asserted-by":"publisher","first-page":"313","DOI":"10.3389\/fphar.2016.00313","article-title":"Nanomedicine-Mediated\nTherapies to Target Breast Cancer Stem Cells","volume":"7","author":"He","year":"2016","journal-title":"Front. Pharmacol."},{"key":"2026081718164492500_cit22","doi-asserted-by":"publisher","first-page":"3231","DOI":"10.2217\/nnm.15.163","article-title":"Nanomedicine Delivery: Does Protein Corona Route to\nthe Target or Off Road?","volume":"10","author":"Maiolo","year":"2015","journal-title":"Nanomedicine (London,\nU. K.)"},{"key":"2026081718164492500_cit23","doi-asserted-by":"publisher","first-page":"283","DOI":"10.1002\/ddr.21399","article-title":"RGD Peptide-Based Target\nDrug Delivery of Doxorubicin Nanomedicine","volume":"78","author":"Sun","year":"2017","journal-title":"Drug\nDev. Res."},{"key":"2026081718164492500_cit24","doi-asserted-by":"publisher","first-page":"1555","DOI":"10.2217\/nnm.15.14","article-title":"Metabolic and Structural Integrity\nof Magnetic Nanoparticle-Loaded Primary Endothelial Cells for Targeted\nCell Therapy","volume":"10","author":"Orynbayeva","year":"2015","journal-title":"Nanomedicine (London, U. K.)"},{"key":"2026081718164492500_cit25","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0003253","article-title":"Rapid Nanoparticle-Mediated\nMonitoring\nof Bacterial Metabolic Activity and Assessment of Antimicrobial Susceptibility\nin Blood with Magnetic Relaxation","volume":"3","author":"Kaittanis","year":"2008","journal-title":"PLoS One"},{"key":"2026081718164492500_cit26","doi-asserted-by":"publisher","first-page":"015102","DOI":"10.1088\/1361-6528\/aa96eb","article-title":"Engineered\nCore-Shell Magnetic Nanoparticle\nfor MR Dual-Modal Tracking and Safe Magnetic Manipulation of Ependymal\nCells in Live Rodent","volume":"29","author":"Yung-Kang","year":"2018","journal-title":"Nanotechnology"},{"key":"2026081718164492500_cit27","doi-asserted-by":"publisher","first-page":"6155","DOI":"10.1016\/j.biomaterials.2011.05.019","article-title":"Iron Oxide Nanoparticle-Containing\nMicrobubble Composites as Contrast Agents for MR and Ultrasound Dual-Modality\nImaging","volume":"32","author":"Liu","year":"2011","journal-title":"Biomaterials"},{"key":"2026081718164492500_cit28","doi-asserted-by":"publisher","first-page":"11394","DOI":"10.1073\/pnas.0905487106","article-title":"Pharmacokinetics\nand Tumor Dynamics of the Nanoparticle IT-101 from PET Imaging and\nTumor Histological Measurements","volume":"106","author":"Schluep","year":"2009","journal-title":"Proc. Natl.\nAcad. Sci. U. S. A."},{"key":"2026081718164492500_cit29","doi-asserted-by":"publisher","first-page":"146","DOI":"10.1016\/j.jpba.2017.01.028","article-title":"Preparation and (68)\u00adGa-Radiolabeling\nof Porous Zirconia Nanoparticle Platform for PET\/CT-Imaging Guided\nDrug Delivery","volume":"137","author":"Polyak","year":"2017","journal-title":"J. Pharm. Biomed. Anal."},{"key":"2026081718164492500_cit30","doi-asserted-by":"publisher","first-page":"8114","DOI":"10.1016\/j.biomaterials.2013.07.078","article-title":"Hybrid\nPET\/MR Imaging of Tumors Using an Oleanolic\nAcid-Conjugated Nanoparticle","volume":"34","author":"Kim","year":"2013","journal-title":"Biomaterials"},{"key":"2026081718164492500_cit31","doi-asserted-by":"publisher","first-page":"4434","DOI":"10.1021\/nl902715v","article-title":"A Highly Effective, Nontoxic T1MR\nContrast Agent Based\non Ultrasmall PEGylated Iron Oxide Nanoparticles","volume":"9","author":"Tromsdorf","year":"2009","journal-title":"Nano Lett."},{"key":"2026081718164492500_cit32","doi-asserted-by":"publisher","first-page":"1161","DOI":"10.1021\/tx300064m","article-title":"Bone as Target Organ for Metals:\nThe Case of F-Elements","volume":"25","author":"Vidaud","year":"2012","journal-title":"Chem. Res. Toxicol."},{"key":"2026081718164492500_cit33","doi-asserted-by":"publisher","first-page":"135","DOI":"10.1016\/j.canlet.2012.04.001","article-title":"Bone-Targeting\nRadiopharmaceuticals for the Treatment\nof Prostate Cancer with Bone Metastases","volume":"323","author":"Goyal","year":"2012","journal-title":"Cancer\nLett."},{"key":"2026081718164492500_cit34","doi-asserted-by":"publisher","first-page":"416","DOI":"10.1016\/j.eururo.2015.09.005","article-title":"Radiopharmaceuticals for Palliation\nof Bone Pain in Patients with Castration-Resistant Prostate Cancer\nMetastatic to Bone: A Systematic Review","volume":"70","author":"Jong","year":"2016","journal-title":"Eur.\nUrol."},{"key":"2026081718164492500_cit35","doi-asserted-by":"publisher","first-page":"370","DOI":"10.1038\/nnano.2015.17","article-title":"Breaking the Depth\nDependency of Phototherapy with Cerenkov Radiation and Low-Radiance-Responsive\nNanophotosensitizers","volume":"10","author":"Kotagiri","year":"2015","journal-title":"Nat. Nanotechnol."},{"key":"2026081718164492500_cit36","doi-asserted-by":"publisher","first-page":"1101","DOI":"10.2217\/nnm-2017-0077","article-title":"Nanophotosensitive\nDrugs for Light-Based Cancer Therapy: What Does the Future Hold?","volume":"12","author":"Tang","year":"2017","journal-title":"Nanomedicine (London, U. K.)"},{"key":"2026081718164492500_cit37","doi-asserted-by":"publisher","first-page":"275","DOI":"10.1038\/s41467-017-02758-9","article-title":"Radionuclides\nTransform Chemotherapeutics into Phototherapeutics for Precise Treatment\nof Disseminated Cancer","volume":"9","author":"Kotagiri","year":"2018","journal-title":"Nat. Commun."},{"key":"2026081718164492500_cit38","doi-asserted-by":"publisher","first-page":"878","DOI":"10.1007\/s11095-012-0929-8","article-title":"89)\u00adZr-Labeled Paramagnetic\nOctreotide-Liposomes for PET-MR Imaging of Cancer","volume":"30","author":"Abou","year":"2013","journal-title":"Pharm. Res."},{"key":"2026081718164492500_cit39","doi-asserted-by":"publisher","first-page":"1293","DOI":"10.2967\/jnumed.110.076174","article-title":"89Zr-DFO-J591 for Immunopet\nof Prostate-Specific Membrane Antigen Expression In Vivo","volume":"51","author":"Holland","year":"2010","journal-title":"J. Nucl. Med."},{"key":"2026081718164492500_cit40","doi-asserted-by":"publisher","first-page":"225","DOI":"10.1039\/C4SC02778G","article-title":"Chelate-Free\nMetal Ion Binding and Heat-Induced Radiolabeling of Iron Oxide Nanoparticles","volume":"6","author":"Boros","year":"2015","journal-title":"Chem. Sci."},{"key":"2026081718164492500_cit41","doi-asserted-by":"publisher","first-page":"13319","DOI":"10.1002\/anie.201306306","article-title":"Chelator-Free\nSynthesis of a Dual-Modality PET\/MRI Agent","volume":"52","author":"Chen","year":"2013","journal-title":"Angew. Chem., Int. Ed."},{"key":"2026081718164492500_cit42","doi-asserted-by":"publisher","first-page":"1600122","DOI":"10.1002\/advs.201600122","article-title":"Engineering Intrinsically Zirconium-89 Radiolabeled Self-Destructing\nMesoporous Silica Nanostructures for In Vivo Biodistribution\nand Tumor Targeting Studies","volume":"3","author":"Goel","year":"2016","journal-title":"Adv. Sci. (Weinh)"},{"key":"2026081718164492500_cit43","first-page":"5591","article-title":"Intrinsically\n(89)\u00adZr-Labeled\nGd2O2S:Eu Nanophosphors with High In\nVivo Stability for Dual-Modality Imaging","volume":"8","author":"Ai","year":"2016","journal-title":"Am. J. Transl. Res."},{"key":"2026081718164492500_cit44","doi-asserted-by":"publisher","first-page":"907","DOI":"10.1038\/aps.2017.1","article-title":"Intrinsic Radiolabeling of Titanium-45 Using Mesoporous Silica Nanoparticles","volume":"38","author":"Chen","year":"2017","journal-title":"Acta Pharmacol. Sin."},{"key":"2026081718164492500_cit45","doi-asserted-by":"publisher","first-page":"1577","DOI":"10.1002\/(SICI)1521-3773(19980619)37:11&lt;1577::AID-ANIE1577&gt;3.0.CO;2-M","article-title":"The First Specific Ti\u00ad(Iv) -Protein\nComplex: Potential Relevance to Anticancer Activity of Titanocenes","volume":"37","author":"Sun","year":"1998","journal-title":"Angew. Chem., Int. Ed."},{"key":"2026081718164492500_cit46","doi-asserted-by":"publisher","first-page":"157","DOI":"10.1016\/S0014-5793(98)01651-2","article-title":"Formation\nof Titanium\u00ad(Iv) Transferrin by Reaction of Human Serum Apotransferrin\nwith Titanium Complexes","volume":"442","author":"Messori","year":"1999","journal-title":"FEBS Lett."},{"key":"2026081718164492500_cit47","doi-asserted-by":"publisher","first-page":"144","DOI":"10.1016\/j.clim.2006.06.010","article-title":"The Transferrin\nReceptor Part I: Biology and Targeting with Cytotoxic Antibodies for\nthe Treatment of Cancer","volume":"121","author":"Daniels","year":"2006","journal-title":"Clin. Immunol."},{"key":"2026081718164492500_cit48","doi-asserted-by":"publisher","first-page":"370","DOI":"10.1038\/nnano.2015.17","article-title":"Breaking the Depth\nDependency of Phototherapy with Cerenkov Radiation and Low-Radiance-Responsive\nNanophotosensitizers","volume":"10","author":"Kotagiri","year":"2015","journal-title":"Nat. Nanotechnol."},{"key":"2026081718164492500_cit49","doi-asserted-by":"publisher","first-page":"29535","DOI":"10.1039\/C5RA00206K","article-title":"Evaluation of\nUndoped and M-Doped TiO2,\nWhere M = Sn, Fe, Ni\/Nb, Zr, V, and Mn, for Lithium-Ion Battery Applications\nPrepared by the Molten-Salt Method","volume":"5","author":"Reddy","year":"2015","journal-title":"RSC Adv."},{"key":"2026081718164492500_cit50","doi-asserted-by":"publisher","first-page":"43","DOI":"10.1016\/j.cplett.2015.03.056","article-title":"Electronic Properties of TiO2 Doped with\nSc, Y, La, Zr, Hf, V, Nb and Ta","volume":"628","author":"Pan","year":"2015","journal-title":"Chem. Phys.\nLett."},{"key":"2026081718164492500_cit51","doi-asserted-by":"publisher","first-page":"2554","DOI":"10.1039\/C7CS00014F","article-title":"The Chemistry of PET Imaging with Zirconium-89","volume":"47","author":"Dilworth","year":"2018","journal-title":"Chem. Soc. 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