{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T11:43:04Z","timestamp":1789731784590,"version":"4.0.1"},"reference-count":42,"publisher":"American Chemical Society (ACS)","issue":"18","license":[{"start":{"date-parts":[[2020,4,28]],"date-time":"2020-04-28T00:00:00Z","timestamp":1588032000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/pubs.acs.org\/page\/policy\/authorchoice_termsofuse.html"}],"funder":[{"DOI":"10.13039\/100000060","name":"National Institute of Allergy and Infectious Diseases","doi-asserted-by":"publisher","award":["1R01AI139100-01"],"award-info":[{"award-number":["1R01AI139100-01"]}],"id":[{"id":"10.13039\/100000060","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,5,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Cetylpyridinium tetrachlorozincate (referred to herein as (CP)2ZnCl4) was synthesized and its solid-state structure was elucidated via single-crystal X-ray diffraction (SC-XRD), revealing a stoichiometry of C42H76Cl4N2Zn with two cetylpyridinium (CP) cations per [ZnCl4]2\u2013 tetrahedra. Crystal structures at 100 and 298 K exhibited a zig-zag pattern with alternating alkyl chains and zinc units. The material showed potential for application as a broad-spectrum antimicrobial agent, to reduce volatile sulfur compounds (VSCs) generated by bacteria, and in the fabrication of advanced functional materials. Minimum inhibitory concentration (MIC) of (CP)2ZnCl4 was 60, 6, and 6 \u03bcg mL\u20131 for Salmonella enterica, Staphylococcus aureus, and Streptococcus mutans, respectively. The MIC values of (CP)2ZnCl4 were comparable to that of pure cetylpyridinium chloride (CPC), despite the fact that approximately 16% of the bactericidal CPC is replaced with bacteriostatic ZnCl2 in the structure. A modified layer-by-layer deposition technique was implemented to synthesize mesoporous silica (i.e., SBA-15) loaded with approximately 9.0 wt % CPC and 8.9 wt % Zn.<\/jats:p>","DOI":"10.1021\/acsomega.0c00131","type":"journal-article","created":{"date-parts":[[2020,4,28]],"date-time":"2020-04-28T14:17:00Z","timestamp":1588083420000},"page":"10359-10365","source":"Crossref","is-referenced-by-count":21,"title":["Synthesis, Characterization, and Investigation of\nthe Antimicrobial Activity of Cetylpyridinium Tetrachlorozincate"],"prefix":"10.1021","volume":"5","author":[{"given":"Viktor","family":"Dubovoy","sequence":"first","affiliation":[{"name":"Rutgers, The State University of New Jersey , , 610 Taylor Road , , ,","place":["Piscataway, New Jersey, United States, 08854"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shiri","family":"Nawrocki","sequence":"additional","affiliation":[{"name":"Rutgers Robert Wood Johnson Medical School , , 675 Hoes Lane West , , 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Bacteriol."},{"key":"2026090301272892800_cit41","volume-title":"Methods for Dilution Antimicrobial Susceptibility Tests for Bacteria\nThat Grow Aerobically; Approved Standard","year":"2012","edition":"9"},{"key":"2026090301272892800_cit42","doi-asserted-by":"publisher","DOI":"10.1126\/science.aaa2491","article-title":"Technology-driven layer-by-layer\nassembly of nanofilms","volume":"348","author":"Richardson","year":"2015","journal-title":"Science"}],"container-title":["ACS Omega"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsomega.0c00131","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/acsodf\/article-pdf\/5\/18\/10359\/6384809\/ao0c00131.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/pubs.acs.org\/acsodf\/article-pdf\/5\/18\/10359\/6384809\/ao0c00131.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T05:27:34Z","timestamp":1788413254000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/acsodf\/article\/5\/18\/10359\/619004\/Synthesis-Characterization-and-Investigation-of"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,4,28]]},"references-count":42,"journal-issue":{"issue":"18","published-online":{"date-parts":[[2020,4,28]]},"published-print":{"date-parts":[[2020,5,12]]}},"URL":"https:\/\/doi.org\/10.1021\/acsomega.0c00131","relation":{},"ISSN":["2470-1343"],"issn-type":[{"value":"2470-1343","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,4,28]]}}}