{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T03:07:35Z","timestamp":1791515255035,"version":"4.3.4"},"reference-count":68,"publisher":"American Chemical Society (ACS)","issue":"31","license":[{"start":{"date-parts":[[2021,7,26]],"date-time":"2021-07-26T00:00:00Z","timestamp":1627257600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ACS Omega"],"published-print":{"date-parts":[[2021,8,10]]},"DOI":"10.1021\/acsomega.1c02340","type":"journal-article","created":{"date-parts":[[2021,7,26]],"date-time":"2021-07-26T18:29:10Z","timestamp":1627324150000},"page":"20492-20511","source":"Crossref","is-referenced-by-count":42,"title":["Phenolic Profiling and Therapeutic Potential of Certain Isolated Compounds from\n                    <i>Parkia roxburghii<\/i>\n                    against AChE Activity as well as GABA\n                    <sub>A<\/sub>\n                    \u03b15, GSK-3\u03b2, and p38\u03b1 MAP-Kinase Genes"],"prefix":"10.1021","volume":"6","author":[{"given":"Heba A.","family":"El Gizawy","sequence":"first","affiliation":[{"name":"Pharmacognosy Department, Faculty of Pharmacy, October 6 University, 12585 6th of October City, Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heba M.","family":"Abo-Salem","sequence":"additional","affiliation":[{"name":"Chemistry and Natural Compounds Department, Pharmaceutical and Drug Industries Research Division, National Research Center, Dokki, 12585 Giza, Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ali A.","family":"Ali","sequence":"additional","affiliation":[{"name":"Postgraduate Studies, October 6 University, 12585 Sixth of October City, Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1811-2794","authenticated-orcid":true,"given":"Mohammed A.","family":"Hussein","sequence":"additional","affiliation":[{"name":"Biochemistry Department, Faculty of Applied Medical Sciences, October 6 University, 12585 Sixth of October City, Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2021,7,26]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1177\/070674371105601004"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1038\/nrneurol.2011.2"},{"key":"ref3\/cit3","unstructured":"World Health Organization (WHO). Dementia. 21 September 2020. Available online: https:\/\/www.who.int\/news-room\/fact-sheets\/detail\/dementia."},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1007\/s12576-016-0497-5"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1038\/nrn1625"},{"key":"ref6\/cit6","first-page":"1","volume-title":"Underutilized Vegetables and Legume","author":"Singhania N.","year":"2021"},{"key":"ref7\/cit7","first-page":"680","volume":"6","author":"Seal T.","year":"2014","journal-title":"J. Chem. Pharm. Res"},{"key":"ref8\/cit8","first-page":"1","volume":"12","author":"Zuhud E. A. M.","year":"2001","journal-title":"Jurnal Teknologi Dan Industri Pangan"},{"key":"ref9\/cit9","first-page":"89","volume":"1","author":"Siswoyo E.","year":"1993","journal-title":"Media Konse Msi"},{"key":"ref10\/cit10","first-page":"2292","volume":"25","author":"Rashed K.","year":"2018","journal-title":"Int. Food Res. J."},{"key":"ref11\/cit11","first-page":"502","volume":"68","author":"Salam J. S.","year":"1995","journal-title":"Curr. Sci."},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1016\/j.etap.2012.06.008"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodhyd.2010.11.004"},{"key":"ref14\/cit14","unstructured":"Sonia, N.; Alisha, D. M. Pharmacological evaluation of\n                      Parkia speciosa\n                      Hassk. for antioxidant, anti-inflammatory, anti-diabetic and anti-microbial activities in vitro\n                      Int. J. Life Sci.\n                      2018. Special Issue A 11 January."},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcs.2012.07.014"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodchem.2005.01.032"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1016\/S0378-8741(00)00261-0"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1093\/clinchem\/28.10.2077"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1016\/0003-2697(75)90728-9"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1006\/abio.1987.9999"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1016\/0003-2697(81)90281-5"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.90.19.9031"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1093\/emboj\/16.5.989"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1038\/6675"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1021\/jp9624257"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1080\/03758397.1957.10857373"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.3923\/ijbc.2012.130.135"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.5567\/pharmacologia.2012.84.90"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1186\/s12858-018-0095-7"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1021\/jf9707546"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1155\/2014\/561459"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1021\/acsomega.9b02205"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1021\/jm020017n"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1023\/A:1020444330011"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1016\/j.neubiorev.2010.04.001"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1016\/j.jep.2012.12.047"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1097\/01.NPR.0000463782.57968.c2"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1016\/j.jns.2010.03.002"},{"key":"ref39\/cit39","first-page":"4560","volume":"40","author":"Shu-xia Y.","year":"2015","journal-title":"Zhongguo Zhong Yao Za Zhi"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.1016\/j.heliyon.2020.e04337"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.3390\/ijms14011310"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.89.5.1671"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.3831\/KPI.2016.19.018"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2567.2004.01976.x"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.2741\/2199"},{"key":"ref46\/cit46","doi-asserted-by":"publisher","DOI":"10.1038\/nrn2038"},{"key":"ref47\/cit47","doi-asserted-by":"publisher","DOI":"10.1080\/13880209.2019.1634741"},{"key":"ref48\/cit48","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2018.00665"},{"key":"ref49\/cit49","doi-asserted-by":"publisher","DOI":"10.1002\/jms.3243"},{"key":"ref50\/cit50","doi-asserted-by":"publisher","DOI":"10.1155\/2012\/921941"},{"key":"ref51\/cit51","doi-asserted-by":"publisher","DOI":"10.3389\/fnmol.2019.00179"},{"key":"ref52\/cit52","doi-asserted-by":"publisher","DOI":"10.1016\/bs.apha.2014.10.007"},{"key":"ref53\/cit53","doi-asserted-by":"publisher","DOI":"10.1016\/s0014-2999(03)01309-8"},{"key":"ref54\/cit54","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-4159.2008.05578.x"},{"key":"ref55\/cit55","doi-asserted-by":"publisher","DOI":"10.1007\/s00406-008-0828-5"},{"key":"ref56\/cit56","doi-asserted-by":"publisher","DOI":"10.3233\/ADR-190135"},{"key":"ref57\/cit57","doi-asserted-by":"publisher","DOI":"10.1089\/jmf.2010.0310"},{"key":"ref58\/cit58","doi-asserted-by":"publisher","DOI":"10.1271\/bbb.68.119"},{"key":"ref59\/cit59","doi-asserted-by":"publisher","DOI":"10.1021\/jf001413m"},{"key":"ref60\/cit60","doi-asserted-by":"publisher","DOI":"10.1155\/2015\/925432"},{"key":"ref61\/cit61","doi-asserted-by":"publisher","DOI":"10.1186\/1478-811X-7-20"},{"key":"ref62\/cit62","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuropharm.2011.07.033"},{"key":"ref63\/cit63","doi-asserted-by":"publisher","DOI":"10.1007\/s12263-007-0056-z"},{"key":"ref64\/cit64","doi-asserted-by":"publisher","DOI":"10.3390\/molecules24020298"},{"key":"ref65\/cit65","doi-asserted-by":"publisher","DOI":"10.1038\/nri2423"},{"key":"ref66\/cit66","doi-asserted-by":"publisher","DOI":"10.1007\/s00011-009-0077-8"},{"key":"ref67\/cit67","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejphar.2013.09.023"},{"key":"ref68\/cit68","doi-asserted-by":"publisher","DOI":"10.3390\/molecules21091240"}],"container-title":["ACS Omega"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsomega.1c02340","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsomega.1c02340","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,26]],"date-time":"2023-04-26T11:39:30Z","timestamp":1682509170000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acsomega.1c02340"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,7,26]]},"references-count":68,"journal-issue":{"issue":"31","published-print":{"date-parts":[[2021,8,10]]}},"alternative-id":["10.1021\/acsomega.1c02340"],"URL":"https:\/\/doi.org\/10.1021\/acsomega.1c02340","relation":{},"ISSN":["2470-1343","2470-1343"],"issn-type":[{"value":"2470-1343","type":"print"},{"value":"2470-1343","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,7,26]]}}}