{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T21:35:13Z","timestamp":1793396113885,"version":"4.5.0"},"reference-count":25,"publisher":"American Chemical Society (ACS)","issue":"31","license":[{"start":{"date-parts":[[2022,7,28]],"date-time":"2022-07-28T00:00:00Z","timestamp":1658966400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,8,9]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Zinc imidazole framework-8, abbreviated as ZIF-8, is a member of the metal organic framework (MOF) family. The chemical architecture of ZIF-8 consists of zinc metal duly coordinated with an organic ligand\/fragment, resulting in a cagelike three-dimensional network with unique porosity. Because of such a unique architecture and physicochemical property, ZIF-8 has recently been explored in various applications such as gas storage, catalysis, electrochemical sensing, drug delivery, etc. Electrochemical sensors are currently a hot topic in scientific advances, where small, portable, Internet of Things (IoT)-enabled devices powered by electrochemical output show a newer path toward chemo and biosensor applications. The unique electrochemical property of ZIF-8 is hence explored widely for possible electrochemical sensor applications. The application and synthesis of the bare ZIF-8 have been widely reported for more than a decade. However, new scientific advancements depict tailoring the bare ZIF-8 structure to achieve smart hybrid ZIF-8 materials that show more advanced properties compared to bare ZIF-8. The framework is formed by joining inorganic (metal-containing) units with organic linkers by reticular synthesis, which results in the formation of a cross-linked crystalline network with permanent porosity. This unique porosity of ZIF-8 has recently been utilized for the encapsulation of suitable guest species to enhance the native physicochemical activity of ZIF-8. These engineered ZIF-8 materials show excellent results, especially for electrochemical sensing application. This review is intended to describe the research, including the one done by our group, where the ZIF-8 pore size is used for encapsulating nanoparticles, enzymes, and organic compounds to avail suitable sensor applications.<\/jats:p>","DOI":"10.1021\/acsomega.2c00737","type":"journal-article","created":{"date-parts":[[2022,7,28]],"date-time":"2022-07-28T15:42:30Z","timestamp":1659022950000},"page":"26993-27003","source":"Crossref","is-referenced-by-count":171,"title":["Engineering the\nZIF-8 Pore for Electrochemical\nSensor Applications\u2500A Mini Review"],"prefix":"10.1021","volume":"7","author":[{"given":"Anirban","family":"Paul","sequence":"first","affiliation":[{"name":"University of Texas at Dallas , , , ,","place":["Richardson, Texas, United States, 75080"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ivneet Kaur","family":"Banga","sequence":"additional","affiliation":[{"name":"University of Texas at Dallas , , , ,","place":["Richardson, Texas, United States, 75080"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8761-7278","authenticated-orcid":true,"given":"Sriram","family":"Muthukumar","sequence":"additional","affiliation":[{"name":"University of Texas at Dallas , , , ,","place":["Richardson, Texas, United States, 75080"]},{"name":"Enlisense LLC , , ,","place":["Allen, Texas, United States, 75013"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2404-3801","authenticated-orcid":true,"given":"Shalini","family":"Prasad","sequence":"additional","affiliation":[{"name":"University of Texas at Dallas , , , ,","place":["Richardson, Texas, United States, 75080"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2022,7,28]]},"reference":[{"issue":"1","key":"2026090711142285900_cit1","doi-asserted-by":"publisher","first-page":"4068","DOI":"10.1038\/s41467-020-17755-8","article-title":"Understanding\nthe Diversity of the Metal-Organic Framework Ecosystem","volume":"11","author":"Moosavi","year":"2020","journal-title":"Nat. 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