{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,8]],"date-time":"2026-06-08T17:41:36Z","timestamp":1780940496360,"version":"3.54.1"},"reference-count":68,"publisher":"American Chemical Society (ACS)","issue":"33","license":[{"start":{"date-parts":[[2022,8,10]],"date-time":"2022-08-10T00:00:00Z","timestamp":1660089600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100016714","name":"University of Sharjah","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100016714","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002724","name":"American University of Sharjah","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002724","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ACS Omega"],"published-print":{"date-parts":[[2022,8,23]]},"DOI":"10.1021\/acsomega.2c01614","type":"journal-article","created":{"date-parts":[[2022,8,10]],"date-time":"2022-08-10T07:25:10Z","timestamp":1660116310000},"page":"28797-28805","source":"Crossref","is-referenced-by-count":9,"title":["Novel Antiamoebic Tyrocidine-Derived Peptide against Brain-Eating Amoebae"],"prefix":"10.1021","volume":"7","author":[{"given":"Noor","family":"Akbar","sequence":"first","affiliation":[{"name":"College of Arts and Sciences, American University of Sharjah, University City, Sharjah 26666, United Arab Emirates"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0159-2816","authenticated-orcid":true,"given":"Wendy E.","family":"Kaman","sequence":"additional","affiliation":[{"name":"Department of Oral Biochemistry, Academic Centre for Dentistry Amsterdam, University of Amsterdam and VU University Amsterdam, 1081 LA Amsterdam, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maarten","family":"Sarink","sequence":"additional","affiliation":[{"name":"Erasmus MC, University Medical Center Rotterdam, Department of Medical Microbiology and Infectious Diseases, Wytemaweg 80, 3015 CE Rotterdam, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kamran","family":"Nazmi","sequence":"additional","affiliation":[{"name":"Department of Oral Biochemistry, Academic Centre for Dentistry Amsterdam, University of Amsterdam and VU University Amsterdam, 1081 LA Amsterdam, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Floris J.","family":"Bikker","sequence":"additional","affiliation":[{"name":"Department of Oral Biochemistry, Academic Centre for Dentistry Amsterdam, University of Amsterdam and VU University Amsterdam, 1081 LA Amsterdam, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7667-8553","authenticated-orcid":true,"given":"Naveed Ahmed","family":"Khan","sequence":"additional","affiliation":[{"name":"Department of Clinical Sciences, College of Medicine, University of Sharjah, University City, Sharjah 27272, Unites Arab Emirates"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruqaiyyah","family":"Siddiqui","sequence":"additional","affiliation":[{"name":"College of Arts and Sciences, American University of Sharjah, University City, Sharjah 26666, United Arab Emirates"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2022,8,10]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1111\/jeu.12186"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1051\/parasite\/2015010"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2018.00414"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1080\/21678707.2019.1571904"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1016\/j.pt.2019.10.008"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1016\/S2666-5247(21)00093-8"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2020.616213"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1007\/s00436-014-3932-7"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1016\/j.sjbs.2021.01.030"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1111\/j.1574-6976.2006.00023.x"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1186\/1756-3305-5-6"},{"key":"ref12\/cit12","unstructured":"Siddiqui, R.; Ali, I. K. M.; Cope, J. R.; Khan, N. A. Brain-eating Amoebae; Caister Academic Press: Poole, U.K. 2016, 21\u201326."},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1016\/j.actatropica.2016.09.009"},{"key":"ref14\/cit14","first-page":"255","volume-title":"Neurol. Comp. Infectious Disease","author":"Cope J. R.","year":"2021"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.12659\/AJCR.923219"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1111\/j.1550-7408.1990.tb01142.x"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpara.2009.06.004"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(20)30933-6"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0003017"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1021\/acschemneuro.9b00111"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1080\/14787210.2021.1882302"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciaa520"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejop.2020.125760"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.67.7.2927-2931.2001"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.3390\/biom11091320"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1080\/14787210.2021.1927712"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.01293-15"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-030-01751-4_58-3"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.13698"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1111\/cns.12225"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1021\/acschemneuro.8b00484"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1007\/s11274-018-2437-4"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.3390\/microorganisms8071037"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.3389\/fcimb.2021.668632"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1099\/mic.0.078840-0"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1139\/o11-085"},{"key":"ref37\/cit37","unstructured":"Kaman, W. E. Chirality: The key to specific bacterial protease-based diagnosis? Ph.D. thesis, Erasmus University Rotterdam, Rotterdam, The Netherlands, 2014. http:\/\/hdl.handle.net\/1765\/50385."},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0118853"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.1111\/lam.12867"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.1099\/jmm.0.47134-0"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.02223-19"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.3347\/kjp.2017.55.3.233"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.1021\/acsomega.1c01137"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.1111\/j.1550-7408.2009.00402.x"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.1177\/2050312118781962"},{"key":"ref46\/cit46","doi-asserted-by":"publisher","DOI":"10.3390\/antibiotics8040164"},{"key":"ref47\/cit47","doi-asserted-by":"publisher","DOI":"10.1016\/j.ab.2013.06.015"},{"key":"ref48\/cit48","doi-asserted-by":"publisher","DOI":"10.1016\/B978-008043404-9\/50018-8"},{"key":"ref49\/cit49","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-019-52738-w"},{"key":"ref50\/cit50","doi-asserted-by":"publisher","DOI":"10.1016\/j.protis.2020.125791"},{"key":"ref51\/cit51","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.02300-16"},{"key":"ref52\/cit52","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2362.1979.tb01676.x"},{"key":"ref53\/cit53","doi-asserted-by":"publisher","DOI":"10.3389\/fendo.2019.00730"},{"key":"ref54\/cit54","doi-asserted-by":"publisher","DOI":"10.1111\/j.1550-7408.1983.tb02936.x"},{"key":"ref55\/cit55","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.38.6.1314"},{"key":"ref56\/cit56","doi-asserted-by":"publisher","DOI":"10.1007\/s00018-021-03784-z"},{"key":"ref57\/cit57","doi-asserted-by":"publisher","DOI":"10.1007\/s10989-020-10075-x"},{"key":"ref58\/cit58","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.2009.178236"},{"key":"ref59\/cit59","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9394(14)77020-5"},{"key":"ref60\/cit60","doi-asserted-by":"publisher","DOI":"10.1017\/S0031182009006283"},{"key":"ref61\/cit61","doi-asserted-by":"publisher","DOI":"10.1016\/j.preteyeres.2017.03.004"},{"key":"ref62\/cit62","doi-asserted-by":"publisher","DOI":"10.1111\/cxo.13125"},{"key":"ref63\/cit63","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.36.6.1263"},{"key":"ref64\/cit64","doi-asserted-by":"publisher","DOI":"10.3390\/pathogens9050405"},{"key":"ref65\/cit65","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-020-18711-2"},{"key":"ref66\/cit66","doi-asserted-by":"publisher","DOI":"10.1007\/s10123-021-00201-0"},{"key":"ref67\/cit67","doi-asserted-by":"publisher","DOI":"10.1016\/j.micpath.2007.06.008"},{"key":"ref68\/cit68","doi-asserted-by":"publisher","DOI":"10.1111\/jeu.12857"}],"container-title":["ACS Omega"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsomega.2c01614","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsomega.2c01614","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,27]],"date-time":"2023-04-27T00:11:47Z","timestamp":1682554307000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acsomega.2c01614"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,8,10]]},"references-count":68,"journal-issue":{"issue":"33","published-print":{"date-parts":[[2022,8,23]]}},"alternative-id":["10.1021\/acsomega.2c01614"],"URL":"https:\/\/doi.org\/10.1021\/acsomega.2c01614","relation":{},"ISSN":["2470-1343","2470-1343"],"issn-type":[{"value":"2470-1343","type":"print"},{"value":"2470-1343","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,8,10]]}}}