{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T15:24:21Z","timestamp":1786980261963,"version":"build-2736575974"},"reference-count":41,"publisher":"American Chemical Society (ACS)","issue":"27","license":[{"start":{"date-parts":[[2022,6,23]],"date-time":"2022-06-23T00:00:00Z","timestamp":1655942400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100008402","name":"Chengdu University of Traditional Chinese Medicine","doi-asserted-by":"publisher","award":["XGZX2017"],"award-info":[{"award-number":["XGZX2017"]}],"id":[{"id":"10.13039\/501100008402","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004829","name":"Department of Science and Technology of Sichuan Province","doi-asserted-by":"publisher","award":["2020YFS0524"],"award-info":[{"award-number":["2020YFS0524"]}],"id":[{"id":"10.13039\/501100004829","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004829","name":"Department of Science and Technology of Sichuan Province","doi-asserted-by":"publisher","award":["2020YJ0173"],"award-info":[{"award-number":["2020YJ0173"]}],"id":[{"id":"10.13039\/501100004829","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005891","name":"State Administration of Traditional Chinese Medicine of the People's Republic of China","doi-asserted-by":"publisher","award":["ZYYCXTD-D-202209"],"award-info":[{"award-number":["ZYYCXTD-D-202209"]}],"id":[{"id":"10.13039\/501100005891","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,7,12]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Common pathogenic bacteria contaminate the environment through various modes of transmission. It is thus crucial to develop simple preparation methods of residue-free environmental disinfectants. \u03b2-Lactam antibiotics are frequently prescribed in clinical practice to treat bacterial infections. In this study, we used electrochemical exfoliation to synthesize graphene oxide (GO) with abundant ketene functional groups. A residue-free GO\u2212\u03b2-lactam (GO\u03b2L) was subsequently obtained by mixing ketene and azomethine-H via a [2 + 2] cycloaddition reaction in the aqueous phase. GO\u03b2L has shown broad-spectrum bacterial inhibition against four bacteria (Staphylococcus aureus, Escherichia coli, Salmonella enterica, and Shigella dysenteriae), and it degrades rapidly within 24 h. This study provides a fast and easy method for the synthesis of GO\u03b2L, which can be employed as a promising environmental bacteriostatic disinfectant in real-life applications.<\/jats:p>","DOI":"10.1021\/acsomega.2c02328","type":"journal-article","created":{"date-parts":[[2022,6,23]],"date-time":"2022-06-23T14:47:39Z","timestamp":1655995659000},"page":"23708-23716","source":"Crossref","is-referenced-by-count":2,"title":["Fast Synthesis of Graphene Oxide\u2212\u03b2-Lactam\nas a Residue-Free Environmental Bacterial Inhibitor"],"prefix":"10.1021","volume":"7","author":[{"given":"Chenyan","family":"Hu","sequence":"first","affiliation":[{"name":"Chengdu University of Traditional Chinese Medicine , , , ,","place":["Chengdu, Sichuan, China, 611137"]},{"name":"People\u2019s Hospital of Xinjin District , , , ,","place":["Chengdu, Sichuan, China, 611430"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pengfei","family":"Heng","sequence":"additional","affiliation":[{"name":"Chengdu University of Traditional Chinese Medicine , , , ,","place":["Chengdu, Sichuan, China, 611137"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuanyuan","family":"Zeng","sequence":"additional","affiliation":[{"name":"Chengdu University of Traditional Chinese Medicine , , , ,","place":["Chengdu, Sichuan, China, 611137"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qing","family":"Zhang","sequence":"additional","affiliation":[{"name":"Xihua University , , , ,","place":["Chengdu, Sichuan, China, 610039"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Meilian","family":"Zhao","sequence":"additional","affiliation":[{"name":"Chengdu University of Traditional Chinese Medicine , , , ,","place":["Chengdu, Sichuan, China, 611137"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhongzhu","family":"Yang","sequence":"additional","affiliation":[{"name":"Chengdu University of Traditional Chinese Medicine , , , ,","place":["Chengdu, Sichuan, China, 611137"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0163-4307","authenticated-orcid":true,"given":"Yang","family":"He","sequence":"additional","affiliation":[{"name":"Chengdu University of Traditional Chinese Medicine , , , ,","place":["Chengdu, Sichuan, China, 611137"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2022,6,23]]},"reference":[{"issue":"12","key":"2026081710130207500_cit1","doi-asserted-by":"publisher","first-page":"5327","DOI":"10.1111\/1462-2920.15243","article-title":"Determining the Prevalence,\nIdentity and Possible Origin of Bacterial Pathogens in Soil","volume":"22","author":"Ferraresso","year":"2020","journal-title":"Environ. 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Agents Chemother."},{"issue":"12","key":"2026081710130207500_cit29","doi-asserted-by":"publisher","first-page":"2888","DOI":"10.3390\/molecules25122888","article-title":"Resistance\nof Gram-Positive Bacteria\nto Current Antibacterial Agents and Overcoming Approaches","volume":"25","author":"Jubeh","year":"2020","journal-title":"Molecules"},{"issue":"1","key":"2026081710130207500_cit30","doi-asserted-by":"publisher","first-page":"11","DOI":"10.1186\/s12302-021-00456-4","article-title":"High Concentration\nand High Dose\nof Disinfectants and Antibiotics Used during the COVID-19 Pandemic\nThreaten Human Health","volume":"33","author":"Chen","year":"2021","journal-title":"Environ. Sci. Eur."},{"key":"2026081710130207500_cit31","doi-asserted-by":"publisher","first-page":"159","DOI":"10.1016\/j.crtox.2021.02.008","article-title":"Excessive\nUse of Disinfectants against COVID-19 Posing a Potential Threat to\nLiving Beings","volume":"2","author":"Ghafoor","year":"2021","journal-title":"Curr. 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