{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T15:26:57Z","timestamp":1786980417098,"version":"build-2736575974"},"reference-count":50,"publisher":"American Chemical Society (ACS)","issue":"45","license":[{"start":{"date-parts":[[2022,11,4]],"date-time":"2022-11-04T00:00:00Z","timestamp":1667520000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100012908","name":"Indian Institute of Engineering Science and Technology, Shibpur","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100012908","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001409","name":"Department of Science and Technology, Ministry of Science and Technology, India","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001409","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,11,15]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Cyanide is a very toxic pollutant to aquatic life and the environment. Analytical methods for the quantitative assay of cyanide, which are rapid, sensitive (low limit of detection), and cost-effective, are in great demand. Colorimetric and fluorometric methods are ideally suited for this purpose. In this report, we describe a Ni\u00ad(II) complex containing a pyridoxal platform for the rapid and sensitive fluorometric estimation of cyanide. The square-planar Ni\u00ad(II) complex, [Ni\u00ad(L)\u00ad(N3)]\u00b73H2O, where the ligand LH = 4-[(2-dimethylamino-ethylimino)-methyl]-5-hydroxymtheyl-2-methyl-pyridin-3-ol, a Schiff base formed between pyridoxal and (2-dimethylamino)\u00adethyl amine, was synthesized and characterized by various spectroscopic techniques as well as by single-crystal X-ray structure determination. The complex was found to selectively bind CN\u2013 in the presence of other biologically important anions such as F\u2013, Cl\u2013, Br\u2013, I\u2013, OAc\u2013, S2\u2013, NO3\u2013, PO43\u2013, SO42\u2013, and H2PO4\u2013 in tris-HCl\/NaCl buffer [pH = 7.4], and it can be monitored by fluorescence turn-on or by UV\u2013visible spectroscopy. The binding constant of the complex with CN\u2013 was estimated to be 2.046 \u00d7 1014 M\u20132 and the limit of detection (LOD) was 9 nM, the LOD being considerably lower than the maximum permissible level of cyanide ions (1.9 \u03bcM) in drinking water, as recognized by the World Health Organization (WHO). The effects of pH and temperature on the sensing are also investigated. The Ni\u00ad(II) complex is also found to bind to calf-thymus DNA very strongly, and the apparent binding constant (Kapp) was determined to be 1.33 \u00d7 107 M\u20131 by the fluorescence quenching of the ethidium bromide\u2013DNA adduct by the complex.<\/jats:p>","DOI":"10.1021\/acsomega.2c04063","type":"journal-article","created":{"date-parts":[[2022,11,4]],"date-time":"2022-11-04T02:49:05Z","timestamp":1667530145000},"page":"40941-40949","source":"Crossref","is-referenced-by-count":20,"title":["Selective Turn-On\nFluorescence Sensing of Cyanide\nUsing the Pyridoxal Platform of a Ni(II) Complex"],"prefix":"10.1021","volume":"7","author":[{"given":"Antu","family":"Mondal","sequence":"first","affiliation":[{"name":"Indian Institute of Engineering Science and Technology , , Shibpur, ,","place":["Howrah, India, 711103"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9726-922X","authenticated-orcid":true,"given":"Shyamal Kumar","family":"Chattopadhyay","sequence":"additional","affiliation":[{"name":"Indian Institute of Engineering Science and Technology , , Shibpur, ,","place":["Howrah, India, 711103"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2022,11,4]]},"reference":[{"key":"2026081710090073000_cit1","doi-asserted-by":"publisher","first-page":"6030","DOI":"10.1021\/bi400812r","article-title":"Metal Transfer within\nthe E. 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Biochem."},{"key":"2026081710090073000_cit49","doi-asserted-by":"publisher","first-page":"677","DOI":"10.1016\/j.actbio.2005.07.002","article-title":"New Modulated\nMetallic Macrocycles:\nElectrochemistry and Their Interaction with Calf Thymus DNA","volume":"1","author":"Tabassum","year":"2005","journal-title":"Acta Biomater."},{"key":"2026081710090073000_cit50","doi-asserted-by":"publisher","first-page":"4237","DOI":"10.1021\/bi00067a011","article-title":"GC Base\nSequence Recognition by Oligo (Imidazolecarboxamide) and C-Terminus-Modified\nAnalogues of Distamycin Deduced from Circular Dichroism, Proton Nuclear\nMagnetic Resonance, and Methidiumpropylethylenediaminetetraacetate-Iron\n(II) Footprinting Studies","volume":"32","author":"Lee","year":"1993","journal-title":"Biochemistry"}],"container-title":["ACS Omega"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsomega.2c04063","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/acsodf\/article-pdf\/7\/45\/40941\/12871180\/ao2c04063.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/pubs.acs.org\/acsodf\/article-pdf\/7\/45\/40941\/12871180\/ao2c04063.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T14:49:52Z","timestamp":1786978192000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/acsodf\/article\/7\/45\/40941\/488492\/Selective-Turn-On-Fluorescence-Sensing-of-Cyanide"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,11,4]]},"references-count":50,"journal-issue":{"issue":"45","published-online":{"date-parts":[[2022,11,4]]},"published-print":{"date-parts":[[2022,11,15]]}},"URL":"https:\/\/doi.org\/10.1021\/acsomega.2c04063","relation":{},"ISSN":["2470-1343"],"issn-type":[{"value":"2470-1343","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,11,4]]}}}