{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,12]],"date-time":"2026-06-12T21:29:14Z","timestamp":1781299754285,"version":"3.54.1"},"reference-count":48,"publisher":"American Chemical Society (ACS)","issue":"35","license":[{"start":{"date-parts":[[2023,8,23]],"date-time":"2023-08-23T00:00:00Z","timestamp":1692748800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100023674","name":"Deanship of Scientific Research, King Khalid University","doi-asserted-by":"publisher","award":["RGP.2\/100\/44"],"award-info":[{"award-number":["RGP.2\/100\/44"]}],"id":[{"id":"10.13039\/501100023674","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ACS Omega"],"published-print":{"date-parts":[[2023,9,5]]},"DOI":"10.1021\/acsomega.3c03546","type":"journal-article","created":{"date-parts":[[2023,8,23]],"date-time":"2023-08-23T17:18:26Z","timestamp":1692811106000},"page":"31890-31898","source":"Crossref","is-referenced-by-count":15,"title":["Triazolothiadiazoles and Triazolothiadiazines as New and Potent Urease Inhibitors: Insights from In Vitro Assay, Kinetics Data, and In Silico Assessment"],"prefix":"10.1021","volume":"8","author":[{"given":"Jalal","family":"Uddin","sequence":"first","affiliation":[{"name":"Department of Pharmaceutical Chemistry, College of Pharmacy, King Khalid University, Abha 62529, Kingdom of Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saeed","family":"Ullah","sequence":"additional","affiliation":[{"name":"Natural and Medical Sciences Research Center, University of Nizwa, Birkat-ul-Mouz 616 Nizwa, Sultanate of Oman"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sobia Ahsan","family":"Halim","sequence":"additional","affiliation":[{"name":"Natural and Medical Sciences Research Center, University of Nizwa, Birkat-ul-Mouz 616 Nizwa, Sultanate of Oman"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muhammad","family":"Waqas","sequence":"additional","affiliation":[{"name":"Natural and Medical Sciences Research Center, University of Nizwa, Birkat-ul-Mouz 616 Nizwa, Sultanate of Oman"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1954-0432","authenticated-orcid":true,"given":"Aliya","family":"Ibrar","sequence":"additional","affiliation":[{"name":"Department of Chemistry, Faculty of Natural Sciences, The University of Haripur, Haripur, KPK 22620, Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7359-1727","authenticated-orcid":true,"given":"Imtiaz","family":"Khan","sequence":"additional","affiliation":[{"name":"Department of Chemistry and Manchester Institute of Biotechnology,The University of Manchester, 131 Princess Street, Manchester M1 7DN, U.K."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdullatif","family":"Bin Muhsinah","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Chemistry, College of Pharmacy, King Khalid University, Abha 62529, Kingdom of Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ajmal","family":"Khan","sequence":"additional","affiliation":[{"name":"Natural and Medical Sciences Research Center, University of Nizwa, Birkat-ul-Mouz 616 Nizwa, Sultanate of Oman"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0815-5942","authenticated-orcid":true,"given":"Ahmed","family":"Al-Harrasi","sequence":"additional","affiliation":[{"name":"Natural and Medical Sciences Research Center, University of Nizwa, Birkat-ul-Mouz 616 Nizwa, Sultanate of Oman"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2023,8,23]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jare.2018.01.007"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1517\/13543776.2011.574615"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.00054-05"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1016\/j.jceh.2014.12.003"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1128\/iai.32.1.32-37.1981"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1016\/j.molcatb.2009.01.003"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1002\/ardp.201300041"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijbiomac.2021.12.064"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1039\/C5NJ01879J"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1002\/ardp.202000023"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1007\/s11696-021-01653-4"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-022-17993-4"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1002\/slct.202203297"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1016\/j.jare.2018.05.003"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1016\/j.bioorg.2021.105545"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1007\/BF00014435"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1016\/j.bmc.2004.01.010"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejmech.2011.09.009"},{"issue":"5","key":"ref19\/cit19","first-page":"546","volume":"41","author":"Onoda Y.","year":"1991","journal-title":"Arzneimittelforschung"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1016\/j.bioorg.2021.105076"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.2174\/2215083805666190613125700"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.14233\/ajomc.2021.AJOMC-P325"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.2174\/1385272822666181008142138"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.2174\/1871520620666200705214917"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1016\/j.molstruc.2021.130369"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1016\/j.bmc.2022.116627"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1002\/jhet.3513"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejmech.2013.01.060"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1007\/s00706-007-0718-y"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejmech.2010.08.034"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejmech.2014.03.046"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1016\/j.bmc.2014.08.026"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1039\/C5RA00906E"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1016\/j.molstruc.2019.06.049"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1515\/znb-2014-0162"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1016\/j.molstruc.2009.12.018"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1021\/acsomega.1c03675"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1016\/S0014-827X(01)01028-X"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.1517\/17425255.2.5.715"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.1016\/S0169-409X(96)00423-1"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.1021\/cc9800071"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.1002\/med.10041"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.1021\/ac60252a045"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.1016\/j.bioorg.2019.03.008"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.1007\/BF00124456"},{"key":"ref46\/cit46","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jctc.5b00255"},{"key":"ref47\/cit47","doi-asserted-by":"publisher","DOI":"10.1038\/srep42717"},{"key":"ref48\/cit48","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijbiomac.2023.124428"}],"container-title":["ACS Omega"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsomega.3c03546","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsomega.3c03546","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,5]],"date-time":"2023-09-05T08:13:15Z","timestamp":1693901595000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acsomega.3c03546"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,8,23]]},"references-count":48,"journal-issue":{"issue":"35","published-print":{"date-parts":[[2023,9,5]]}},"alternative-id":["10.1021\/acsomega.3c03546"],"URL":"https:\/\/doi.org\/10.1021\/acsomega.3c03546","relation":{},"ISSN":["2470-1343","2470-1343"],"issn-type":[{"value":"2470-1343","type":"print"},{"value":"2470-1343","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,8,23]]}}}