{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T20:00:07Z","timestamp":1791576007594,"version":"4.3.4"},"reference-count":60,"publisher":"American Chemical Society (ACS)","issue":"41","license":[{"start":{"date-parts":[[2023,9,26]],"date-time":"2023-09-26T00:00:00Z","timestamp":1695686400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000865","name":"Bill and Melinda Gates Foundation","doi-asserted-by":"publisher","award":["GCA\/Round10\/DD-065"],"award-info":[{"award-number":["GCA\/Round10\/DD-065"]}],"id":[{"id":"10.13039\/100000865","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ACS Omega"],"published-print":{"date-parts":[[2023,10,17]]},"DOI":"10.1021\/acsomega.3c04494","type":"journal-article","created":{"date-parts":[[2023,9,26]],"date-time":"2023-09-26T12:22:09Z","timestamp":1695730929000},"page":"38220-38232","source":"Crossref","is-referenced-by-count":34,"title":["Pharmacophore Model-Based Virtual Screening Workflow for Discovery of Inhibitors Targeting\n                    <i>\n                      <i>Plasmodium falciparum<\/i>\n                    <\/i>\n                    Hsp90"],"prefix":"10.1021","volume":"8","author":[{"given":"Ofentse","family":"Mafethe","sequence":"first","affiliation":[{"name":"Department of Biochemistry, North-West University, Mmabatho 2735, South Africa"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tlhalefo","family":"Ntseane","sequence":"additional","affiliation":[{"name":"Department of Biochemistry, North-West University, Mmabatho 2735, South Africa"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tendamudzimu Harmfree","family":"Dongola","sequence":"additional","affiliation":[{"name":"Department of Biochemistry and Microbiology, University of Venda, Thohoyandou 0950, South Africa"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Addmore","family":"Shonhai","sequence":"additional","affiliation":[{"name":"Department of Biochemistry and Microbiology, University of Venda, Thohoyandou 0950, South Africa"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4213-5416","authenticated-orcid":true,"given":"Njabulo Joyfull","family":"Gumede","sequence":"additional","affiliation":[{"name":"Department of Chemical and Physical Sciences, Faculty of Natural Sciences, Walter Sisulu University (WSU), Private Bag X01, Umthatha, Eastern Cape 4099, South Africa"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0864-9157","authenticated-orcid":true,"given":"Fortunate","family":"Mokoena","sequence":"additional","affiliation":[{"name":"Department of Biochemistry, North-West University, Mmabatho 2735, South Africa"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2023,9,26]]},"reference":[{"key":"ref1\/cit1","unstructured":"World Health Organization.\n                      World Malaria Report\n                      . Vol. WHO\/HTM\/GM; World Health Organization. 2021. 238 p."},{"key":"ref2\/cit2","unstructured":"Report WM.\n                      World malaria report\n                      ; World Health\nOrganization 2020, 2020."},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpddr.2021.05.007"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1097\/QCO.0000000000000766"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1172\/JCI21682"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1186\/s12936-019-2716-z"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1038\/s41591-020-1005-2"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1314981"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0075446"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms11901"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1038\/nature10317"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1007\/s12192-011-0299-x"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M211309200"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1186\/1475-2875-2-30"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1097\/00001622-200311000-00003"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbamcr.2011.12.006"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-11-1000"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbamcr.2011.10.008"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejmech.2022.114516"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1007\/s40265-022-01764-6"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M110.155317"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-06-4511"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jmedchem.7b01608"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1038\/nrc2887"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1128\/aac.01799-17"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1002\/prot.22799"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1021\/jm401801t"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.00328-12"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jmedchem.6b00591"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1016\/j.bmcl.2021.127818"},{"key":"ref31\/cit31","volume-title":"Protein Preparation Wizard; Epik, Schr\u00f6dinger, LLC: New York, NY","year":"2021"},{"key":"ref32\/cit32","unstructured":"Schr\u00f6dinger\nRelease 2021\u20132.\n                      Maestro. Maestro. 2021\n                      ; Schr\u00f6dinge (LLC): New York, NY."},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.143.4.901"},{"key":"ref34\/cit34","volume-title":"MacroModel. Schr\u00f6dinger","year":"2021"},{"key":"ref35\/cit35","volume-title":"LigPrep. LigPrep.","year":"2021"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1021\/ja9621760"},{"key":"ref37\/cit37","unstructured":"Schr\u00f6dinger\nRelease 2021\u20132.\n                      Phase. Schr\u00f6dinger.\n2021\n                      ; LLC: New York, NY."},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.105.594929"},{"issue":"2","key":"ref39\/cit39","first-page":"148","volume":"65","author":"Gim\u00e9nez B. G.","year":"2010","journal-title":"Pharmazie."},{"key":"ref40\/cit40","unstructured":"Schr\u00f6dinger\nRelease 2021\u20132.\n                      Glide. Schr\u00f6dinger.\n2021\n                      ; LLC: New York, NY."},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmgm.2008.09.002"},{"key":"ref42\/cit42","unstructured":"Prime. Schr\u00f6dinger\nRelease 2021\u20132.\n                      Schr\u00f6dinger.\n2021\n                      ; LLC New York: NY."},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.1002\/prot.23106"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.4269\/ajtmh.1993.48.739"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.1016\/0022-1759(83)90303-4"},{"key":"ref46\/cit46","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbapap.2019.140282"},{"key":"ref47\/cit47","doi-asserted-by":"publisher","DOI":"10.1016\/j.pep.2003.09.010"},{"key":"ref48\/cit48","doi-asserted-by":"publisher","DOI":"10.3390\/biom10060856"},{"key":"ref49\/cit49","doi-asserted-by":"publisher","DOI":"10.3389\/fmolb.2022.947203"},{"key":"ref50\/cit50","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmgm.2008.04.003"},{"key":"ref51\/cit51","doi-asserted-by":"publisher","DOI":"10.1016\/j.surg.2015.12.029"},{"key":"ref52\/cit52","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M211309200"},{"key":"ref53\/cit53","doi-asserted-by":"publisher","DOI":"10.1126\/science.aan4472"},{"key":"ref54\/cit54","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejmech.2019.06.062"},{"key":"ref55\/cit55","doi-asserted-by":"publisher","DOI":"10.1016\/j.bmcl.2003.08.065"},{"key":"ref56\/cit56","doi-asserted-by":"publisher","DOI":"10.1016\/j.str.2009.02.010"},{"key":"ref57\/cit57","doi-asserted-by":"publisher","DOI":"10.1021\/ci7000346"},{"key":"ref58\/cit58","doi-asserted-by":"publisher","DOI":"10.1021\/jm050362n"},{"key":"ref59\/cit59","doi-asserted-by":"publisher","DOI":"10.1002\/prot.21479"},{"key":"ref60\/cit60","doi-asserted-by":"publisher","DOI":"10.1023\/A:1008068903544"}],"container-title":["ACS Omega"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsomega.3c04494","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsomega.3c04494","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,10,17]],"date-time":"2023-10-17T07:24:04Z","timestamp":1697527444000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acsomega.3c04494"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,9,26]]},"references-count":60,"journal-issue":{"issue":"41","published-print":{"date-parts":[[2023,10,17]]}},"alternative-id":["10.1021\/acsomega.3c04494"],"URL":"https:\/\/doi.org\/10.1021\/acsomega.3c04494","relation":{},"ISSN":["2470-1343","2470-1343"],"issn-type":[{"value":"2470-1343","type":"print"},{"value":"2470-1343","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,9,26]]}}}