{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,14]],"date-time":"2026-08-14T16:41:25Z","timestamp":1786725685115,"version":"build-2736575974"},"reference-count":48,"publisher":"American Chemical Society (ACS)","issue":"42","license":[{"start":{"date-parts":[[2024,9,20]],"date-time":"2024-09-20T00:00:00Z","timestamp":1726790400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100014188","name":"Ministry of Science and ICT, South Korea","doi-asserted-by":"publisher","award":["IITP-2024-RS-2024-00438239"],"award-info":[{"award-number":["IITP-2024-RS-2024-00438239"]}],"id":[{"id":"10.13039\/501100014188","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"publisher","award":["2022H1D3A2A02081592"],"award-info":[{"award-number":["2022H1D3A2A02081592"]}],"id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"publisher","award":["2022R1A2C1010151"],"award-info":[{"award-number":["2022R1A2C1010151"]}],"id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"publisher","award":["2022R1C1C1011328"],"award-info":[{"award-number":["2022R1C1C1011328"]}],"id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Brain Korea 21 Four Program"},{"name":"Research Program for Agriculture Science & Technology Development","award":["RS-2024-00399478"],"award-info":[{"award-number":["RS-2024-00399478"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,10,22]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Raman spectroscopy has emerged as a pivotal analytical instrument, valued for its nondestructive capabilities and its capacity to provide essential material-specific insights. However, the excessive costs associated with commercially available Raman instruments present a barrier to their accessibility for many academic institutions and broader usage. Herein, we introduce an affordable and accessible approach to constructing a versatile Raman instrument capable of accommodating both spectroscopic and microscopic analyses. Through this multimodal approach that concurrently captures Raman signal and image data, we demonstrate color-based alcohol detection, showcase a high signal-to-noise ratio achieved through meticulous hardware design and signal processing, and present a cost-effective, modular design utilizing 3D printing technology. This system offers adaptability to address diverse research needs and requirements. We systematically detail the fabrication process, including the utilization of a 3D printer to produce necessary components, ultimately resulting in the assembly of a functional Raman probe system. Our experiments and subsequent analyses substantiate the accuracy and reliability of the constructed system. Specifically, we conducted experiments involving three distinct samples: water, ethanol, and methanol using the Raman probe, successfully confirming their unique Raman spectra. Furthermore, our Raman probe accurately identified ethanol concentration by assessing mixed samples with varying water-to-ethanol ratios and demonstrated a coefficient of determination value of 0.9993. This underscores the performance of the constructed Raman probe and positions it as a viable option for characterization, particularly in regions where access to conventional Raman probe may be limited.<\/jats:p>","DOI":"10.1021\/acsomega.4c04676","type":"journal-article","created":{"date-parts":[[2024,9,20]],"date-time":"2024-09-20T05:10:42Z","timestamp":1726809042000},"page":"42822-42838","source":"Crossref","is-referenced-by-count":2,"title":["Development of\na 3D Printing-Enabled Cost-Effective\nMultimodal Raman Probe with High Signal-to-noise Ratio Raman Spectrum\nMeasurements"],"prefix":"10.1021","volume":"9","author":[{"given":"Ezekiel\nEdward","family":"Nettey-Oppong","sequence":"first","affiliation":[{"name":"Yonsei University , , ,","place":["Wonju, Republic of Korea, 26493"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2645-7258","authenticated-orcid":true,"given":"Ahmed","family":"Ali","sequence":"additional","affiliation":[{"name":"Sukkur IBA University , , ,","place":["Sukkur, Pakistan, 65200"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiwon","family":"Ahn","sequence":"additional","affiliation":[{"name":"Yonsei University , , ,","place":["Wonju, Republic of Korea, 26493"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Riaz","family":"Muhammad","sequence":"additional","affiliation":[{"name":"Yonsei University , , ,","place":["Wonju, Republic of Korea, 26493"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hyun Jin","family":"Lee","sequence":"additional","affiliation":[{"name":"Yonsei University , , ,","place":["Wonju, Republic of Korea, 26493"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hyun-Woo","family":"Jeong","sequence":"additional","affiliation":[{"name":"Eulji University , , ,","place":["Seongnamsi, Republic of Korea, 13135"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8883-7072","authenticated-orcid":true,"given":"Kyung Min","family":"Byun","sequence":"additional","affiliation":[{"name":"Kyung Hee University , , ,","place":["Yongin, Republic of Korea, 17104"]},{"name":"Kyung Hee University , , ,","place":["Yongin, Republic of Korea, 17104"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seung Ho","family":"Choi","sequence":"additional","affiliation":[{"name":"Yonsei University , , ,","place":["Wonju, Republic of Korea, 26493"]},{"name":"Yonsei University College of Medicine , , ,","place":["Seoul, Republic of Korea, 06229"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2024,9,20]]},"reference":[{"issue":"8","key":"2026081412143122000_cit1","doi-asserted-by":"publisher","first-page":"427","DOI":"10.3390\/chemosensors11080427","article-title":"A Review on Non-Noble Metal Substrates for Surface-Enhanced\nRaman Scattering Detection","volume":"11","author":"Chen","year":"2023","journal-title":"Chemosensors"},{"key":"2026081412143122000_cit2","doi-asserted-by":"publisher","first-page":"90","DOI":"10.1080\/05704928.2023.2181818","article-title":"Flexible surface-enhanced\nRaman scattering substrates toward sampling approaches for on-site\nsensing and diagnosis applications","volume":"59","author":"Linh","year":"2023","journal-title":"Appl. Spectrosc.\nRev."},{"issue":"6","key":"2026081412143122000_cit3","doi-asserted-by":"publisher","first-page":"594","DOI":"10.3390\/bios13060594","article-title":"Simple,\nFast and Convenient Magnetic Bead-Based Sample Preparation for Detecting\nViruses via Raman-Spectroscopy","volume":"13","author":"Pahlow","year":"2023","journal-title":"Biosensors"},{"issue":"8","key":"2026081412143122000_cit4","doi-asserted-by":"publisher","first-page":"590","DOI":"10.3390\/bios12080590","article-title":"Miniaturized\nRaman\ninstruments for SERS-based point-of-care testing on respiratory viruses","volume":"12","author":"Ali","year":"2022","journal-title":"Biosensors"},{"key":"2026081412143122000_cit5","doi-asserted-by":"publisher","first-page":"129303","DOI":"10.1016\/j.snb.2020.129303","article-title":"Portable identification of fentanyl\nanalogues in drugs using surface-enhanced Raman scattering","volume":"330","author":"Wilson","year":"2021","journal-title":"Sens. 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