{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T09:45:24Z","timestamp":1790847924139,"version":"4.1.0"},"reference-count":38,"publisher":"American Chemical Society (ACS)","issue":"10","license":[{"start":{"date-parts":[[2025,3,3]],"date-time":"2025-03-03T00:00:00Z","timestamp":1740960000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100007129","name":"Natural Science Foundation of Shandong Province","doi-asserted-by":"publisher","award":["ZR201807090175"],"award-info":[{"award-number":["ZR201807090175"]}],"id":[{"id":"10.13039\/501100007129","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007129","name":"Natural Science Foundation of Shandong Province","doi-asserted-by":"publisher","award":["ZR2021QC084"],"award-info":[{"award-number":["ZR2021QC084"]}],"id":[{"id":"10.13039\/501100007129","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Weifang Municipal Health Commission","award":["WFWSJK-2023-057"],"award-info":[{"award-number":["WFWSJK-2023-057"]}]},{"name":"Science and technology development project of Weifang","award":["2021GX059"],"award-info":[{"award-number":["2021GX059"]}]},{"name":"Science and technology development project of Weifang","award":["2022ZJ1058"],"award-info":[{"award-number":["2022ZJ1058"]}]},{"name":"Science and technology development project of Weifang","award":["2022ZJ1064"],"award-info":[{"award-number":["2022ZJ1064"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ACS Omega"],"published-print":{"date-parts":[[2025,3,18]]},"DOI":"10.1021\/acsomega.4c08564","type":"journal-article","created":{"date-parts":[[2025,3,4]],"date-time":"2025-03-04T03:10:41Z","timestamp":1741057841000},"page":"10107-10121","source":"Crossref","is-referenced-by-count":1,"title":["Study on the Construction and Anti-Tumor Effect of aPDL1\/aMUC1 Double Antibody Modification of Doxorubicin Liposome"],"prefix":"10.1021","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1215-8967","authenticated-orcid":true,"given":"Shouzhen","family":"Zhao","sequence":"first","affiliation":[{"name":"School of Life Science and Technology","place":["Weifang, China"]},{"name":"Shandong Second Medical University","place":["Weifang, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cuiling","family":"Xuan","sequence":"additional","affiliation":[{"name":"School of Life Science and Technology","place":["Weifang, China"]},{"name":"Shandong Second Medical University","place":["Weifang, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenbin","family":"Diao","sequence":"additional","affiliation":[{"name":"Clinical Laboratory","place":["Weifang, China"]},{"name":"Second People\u2019s Hospital of Weifang","place":["Weifang, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ran","family":"Bai","sequence":"additional","affiliation":[{"name":"School of Life Science and Technology","place":["Weifang, China"]},{"name":"Shandong Second Medical University","place":["Weifang, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fei","family":"Wu","sequence":"additional","affiliation":[{"name":"School of Life Science and Technology","place":["Weifang, China"]},{"name":"Shandong Second Medical University","place":["Weifang, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenjing","family":"Yu","sequence":"additional","affiliation":[{"name":"School of Life Science and Technology","place":["Weifang, China"]},{"name":"Shandong Second Medical University","place":["Weifang, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fan","family":"Yang","sequence":"additional","affiliation":[{"name":"Shandong Kanghua Biotechnology Co., Ltd.","place":["Weifang, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6962-2842","authenticated-orcid":true,"given":"Jingliang","family":"Wu","sequence":"additional","affiliation":[{"name":"School of Life Science and Technology","place":["Weifang, China"]},{"name":"Shandong Second Medical University","place":["Weifang, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Xu","sequence":"additional","affiliation":[{"name":"School of Life Science and Technology","place":["Weifang, China"]},{"name":"Shandong Second Medical University","place":["Weifang, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guosheng","family":"Jiang","sequence":"additional","affiliation":[{"name":"School of Life Science and Technology","place":["Weifang, China"]},{"name":"Shandong Second Medical University","place":["Weifang, China"]},{"name":"Institute of Immunology and Biotechnology Transformation, Binzhou Medical University","place":["Yantai, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhiqin","family":"Gao","sequence":"additional","affiliation":[{"name":"School of Life Science and Technology","place":["Weifang, China"]},{"name":"Shandong Second Medical University","place":["Weifang, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haimei","family":"Li","sequence":"additional","affiliation":[{"name":"School of Life Science and Technology","place":["Weifang, China"]},{"name":"Shandong Second Medical University","place":["Weifang, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2025,3,3]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1016\/S2468-2667(23)00211-6"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21660"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2016.00428"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1023\/A:1010960900254"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1353\/bhm.2002.0096"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-0716-2954-3_18"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1021\/acs.molpharmaceut.3c00451"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1016\/j.bmc.2016.09.043"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpharm.2007.04.037"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21338"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0611533104"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.3390\/molecules26195962"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2021.121110"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1016\/j.lfs.2018.03.023"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.4103\/0973-1482.139267"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.3390\/ijms23031414"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2012.03.020"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.2174\/1567201818666210609161301"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.3390\/molecules27227981"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.0c13372"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1080\/10717544.2022.2154409"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1016\/j.chemphyslip.2013.10.011"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1021\/acs.chemrev.7b00013"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1016\/j.addr.2013.11.009"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1007\/s10047-005-0285-0"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1016\/S0168-3659(99)00248-5"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpharm.2017.02.010"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpharm.2012.11.032"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1007\/s00259-006-0139-x"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201506225"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.34382"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-319-53156-4_5"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1007\/s10555-015-9549-1"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1016\/j.bulcan.2022.08.001"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0176820"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1177\/0300985813493932"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2021.764654"},{"key":"ref38\/cit38","unstructured":"Leung, K. Cy7-Polyethylene glycol-cinnamoyl-Phe-D-Leu-Phe-D-Leu-Phe-Lys-NH(2) Molecular Imaging and Contrast Agent Database (MICAD), 2004."}],"container-title":["ACS Omega"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsomega.4c08564","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsomega.4c08564","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,18]],"date-time":"2025-03-18T08:46:51Z","timestamp":1742287611000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acsomega.4c08564"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,3,3]]},"references-count":38,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2025,3,18]]}},"alternative-id":["10.1021\/acsomega.4c08564"],"URL":"https:\/\/doi.org\/10.1021\/acsomega.4c08564","relation":{},"ISSN":["2470-1343","2470-1343"],"issn-type":[{"value":"2470-1343","type":"print"},{"value":"2470-1343","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,3,3]]}}}