{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,20]],"date-time":"2026-03-20T00:41:36Z","timestamp":1773967296282,"version":"3.50.1"},"reference-count":49,"publisher":"American Chemical Society (ACS)","issue":"23","license":[{"start":{"date-parts":[[2025,6,5]],"date-time":"2025-06-05T00:00:00Z","timestamp":1749081600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001823","name":"Ministerstvo ?kolstv?, Ml?de?e a Telov?chovy","doi-asserted-by":"publisher","award":["CZ.02.1.01\/0.0\/0.0\/17_043\/0009632"],"award-info":[{"award-number":["CZ.02.1.01\/0.0\/0.0\/17_043\/0009632"]}],"id":[{"id":"10.13039\/501100001823","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007397","name":"Univerzita Karlova v Praze","doi-asserted-by":"publisher","award":["PRIMUS 22\/MED\/011"],"award-info":[{"award-number":["PRIMUS 22\/MED\/011"]}],"id":[{"id":"10.13039\/100007397","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100010661","name":"Horizon 2020 Framework Programme","doi-asserted-by":"publisher","award":["857560"],"award-info":[{"award-number":["857560"]}],"id":[{"id":"10.13039\/100010661","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100031478","name":"NextGenerationEU","doi-asserted-by":"publisher","award":["LX22NPO5107"],"award-info":[{"award-number":["LX22NPO5107"]}],"id":[{"id":"10.13039\/100031478","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ACS Omega"],"published-print":{"date-parts":[[2025,6,17]]},"DOI":"10.1021\/acsomega.4c10959","type":"journal-article","created":{"date-parts":[[2025,6,5]],"date-time":"2025-06-05T09:42:36Z","timestamp":1749116556000},"page":"24194-24199","source":"Crossref","is-referenced-by-count":3,"title":["Dementia with Lewy Bodies (DLB), Parkinson\u2019s Disease (PD), and Multiple System Atrophy (MSA) Are Synucleopathies Characterized by Increased Serum Levels of Plasminogen Activator Inhibitor-1 (PAI-1)"],"prefix":"10.1021","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5956-5925","authenticated-orcid":true,"given":"Francesco","family":"Angelucci","sequence":"first","affiliation":[{"name":"Memory Clinic, Department of Neurology, Second Faculty of Medicine","place":["Prague, Czech Republic"]},{"name":"Charles University and Motol University Hospital","place":["Prague, Czech Republic"]},{"name":"International Clinical Research Centre","place":["Brno, Czech Republic"]},{"name":"St. Anne\u2019s University Hospital","place":["Brno, Czech Republic"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zuzana","family":"Nedelska","sequence":"additional","affiliation":[{"name":"Memory Clinic, Department of Neurology, Second Faculty of Medicine","place":["Prague, Czech Republic"]},{"name":"Charles University and Motol University Hospital","place":["Prague, Czech Republic"]},{"name":"International Clinical Research Centre","place":["Brno, Czech Republic"]},{"name":"St. Anne\u2019s University Hospital","place":["Brno, Czech Republic"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Blanka","family":"Napravnikova Manov\u00e1","sequence":"additional","affiliation":[{"name":"Memory Clinic, Department of Neurology, Second Faculty of Medicine","place":["Prague, Czech Republic"]},{"name":"Charles University and Motol University Hospital","place":["Prague, Czech Republic"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Al\u017ebeta","family":"Katonov\u00e1","sequence":"additional","affiliation":[{"name":"Memory Clinic, Department of Neurology, Second Faculty of Medicine","place":["Prague, Czech Republic"]},{"name":"Charles University and Motol University Hospital","place":["Prague, Czech Republic"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vanesa","family":"Jur\u00e1\u0161ov\u00e1","sequence":"additional","affiliation":[{"name":"Memory Clinic, Department of Neurology, Second Faculty of Medicine","place":["Prague, Czech Republic"]},{"name":"Charles University and Motol University Hospital","place":["Prague, Czech Republic"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniela","family":"Svetlikova","sequence":"additional","affiliation":[{"name":"Memory Clinic, Department of Neurology, Second Faculty of Medicine","place":["Prague, Czech Republic"]},{"name":"Charles University and Motol University Hospital","place":["Prague, Czech Republic"]},{"name":"International Clinical Research Centre","place":["Brno, Czech Republic"]},{"name":"St. Anne\u2019s University Hospital","place":["Brno, Czech Republic"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martin","family":"Vyhn\u00e1lek","sequence":"additional","affiliation":[{"name":"Memory Clinic, Department of Neurology, Second Faculty of Medicine","place":["Prague, Czech Republic"]},{"name":"Charles University and Motol University Hospital","place":["Prague, Czech Republic"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jakub","family":"Hort","sequence":"additional","affiliation":[{"name":"Memory Clinic, Department of Neurology, Second Faculty of Medicine","place":["Prague, Czech Republic"]},{"name":"Charles University and Motol University Hospital","place":["Prague, Czech Republic"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"316","published-online":{"date-parts":[[2025,6,5]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1002\/alz.13674"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000004058"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(14)61393-3"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1038\/s41572-022-00382-6"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1186\/s13024-021-00501-z"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1016\/j.nbd.2020.104813"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1016\/j.nbd.2022.105966"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1111\/cns.13082"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1046\/j.1460-9568.2002.02106.x"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1046\/j.1460-9568.2000.00991.x"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1038\/83358"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.3389\/fncel.2015.00427"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbadis.2017.01.023"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0092416"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1160\/TH04-12-0842"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2006.04.013"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.22-06-02125.2002"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1016\/j.tins.2008.09.006"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M112.348128"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.4161\/pri.22850"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1016\/j.mehy.2020.109602"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.3390\/cells11142163"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.3390\/ijms23105516"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1089\/1523086041361596"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehn387"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M112.348128"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1038\/nrneurol.2009.54"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-009-5357-2"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.3233\/JAD-171038"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2023.02.078"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-024-59090-8"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1159\/000540854"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.3390\/ijms22063170"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1016\/j.mehy.2020.109602"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1038\/s41572-022-00382-6"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2024.1432342"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1007\/s00018-022-04378-z"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1002\/glia.22653"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.1007\/s11064-022-03673-2"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.3389\/fnagi.2017.00421"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.1007\/s13205-020-02532-7"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.1016\/j.jchemneu.2015.12.002"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2019-030379"},{"issue":"4","key":"ref44\/cit44","first-page":"709","volume":"24","author":"Yesavage J. A.","year":"1988","journal-title":"Psychopharmacol. Bull."},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.1002\/mds.29005"},{"key":"ref46\/cit46","doi-asserted-by":"publisher","DOI":"10.1002\/mds.26424"},{"key":"ref47\/cit47","doi-asserted-by":"publisher","DOI":"10.1002\/mds.10473"},{"key":"ref48\/cit48","doi-asserted-by":"publisher","DOI":"10.1155\/2012\/719167"},{"key":"ref49\/cit49","doi-asserted-by":"publisher","DOI":"10.3390\/ph15091074"}],"container-title":["ACS Omega"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsomega.4c10959","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsomega.4c10959","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,17]],"date-time":"2025-06-17T08:14:40Z","timestamp":1750148080000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acsomega.4c10959"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6,5]]},"references-count":49,"journal-issue":{"issue":"23","published-print":{"date-parts":[[2025,6,17]]}},"alternative-id":["10.1021\/acsomega.4c10959"],"URL":"https:\/\/doi.org\/10.1021\/acsomega.4c10959","relation":{},"ISSN":["2470-1343","2470-1343"],"issn-type":[{"value":"2470-1343","type":"print"},{"value":"2470-1343","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,6,5]]}}}