{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,13]],"date-time":"2026-09-13T23:56:31Z","timestamp":1789343791197,"version":"build-2803163510"},"reference-count":76,"publisher":"American Chemical Society (ACS)","issue":"16","license":[{"start":{"date-parts":[[2025,3,24]],"date-time":"2025-03-24T00:00:00Z","timestamp":1742774400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100017584","name":"SRM Institute of Science and Technology","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100017584","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ACS Omega"],"published-print":{"date-parts":[[2025,4,29]]},"DOI":"10.1021\/acsomega.5c00838","type":"journal-article","created":{"date-parts":[[2025,3,25]],"date-time":"2025-03-25T05:17:18Z","timestamp":1742879838000},"page":"16874-16883","source":"Crossref","is-referenced-by-count":9,"title":["Label-free Detection of Urine Extracellular Vesicles from Duchenne Muscular Dystrophy Patients Using Surface-Enhanced Raman Spectroscopy Combined with Machine Learning Models"],"prefix":"10.1021","volume":"10","author":[{"given":"Archana","family":"Rajavel","sequence":"first","affiliation":[{"name":"Membrane Protein Interaction Laboratory, Department of Genetic Engineering, School of Bioengineering, SRM Institute of Science and Technology, Kattankulathur, Chengalpattu 603 203, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jayasree","family":"Kumar","sequence":"additional","affiliation":[{"name":"Raman Research Laboratory (RARE Lab), Department of Chemistry","place":["Amaravati, India"]},{"name":"SRM University-AP","place":["Amaravati, India"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Narayanan","family":"Essakipillai","sequence":"additional","affiliation":[{"name":"Department of Computer Applications, Faculty of Science and Humanities, SRM Institute of Science and Technology, Kattankulathur, Chengalpattu 603 203, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ramajayam","family":"Anbazhagan","sequence":"additional","affiliation":[{"name":"Department of Mathematics, Faculty of Engineering and Technology, SRM Institute of Science and Technology, Kattankulathur, Chengalpattu 603 203, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3566-4558","authenticated-orcid":true,"given":"Rajapandiyan","family":"Panneerselvam","sequence":"additional","affiliation":[{"name":"Raman Research Laboratory (RARE Lab), Department of Chemistry","place":["Amaravati, India"]},{"name":"SRM University-AP","place":["Amaravati, India"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jayashree","family":"Ramakrishnan","sequence":"additional","affiliation":[{"name":"Department of Computer Applications, Faculty of Science and Humanities, SRM Institute of Science and Technology, Kattankulathur, Chengalpattu 603 203, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Viswanathan","family":"Venkataraman","sequence":"additional","affiliation":[{"name":"Department of Paediatrics Neurology, Apollo Children\u2019s Hospital, Thousands Lights, Chennai 600 006, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5495-7110","authenticated-orcid":true,"given":"Raja","family":"Natesan Sella","sequence":"additional","affiliation":[{"name":"Membrane Protein Interaction Laboratory, Department of Genetic Engineering, School of Bioengineering, SRM Institute of Science and Technology, Kattankulathur, Chengalpattu 603 203, Tamil Nadu, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2025,3,24]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(18)30024-3"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1002\/mus.10435"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(18)30025-5"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1016\/j.nmd.2019.06.004"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1001\/JAMA.1992.03480190051030"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1007\/BF02913084"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1002\/MUS.880050111"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1038\/ejhg.2014.301"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1136\/jmedgenet-2015-103387"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1186\/s41687-021-00386-y"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1073\/PNAS.1507719112"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1164\/RCCM.200503-322OC"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1186\/s13023-017-0631-3"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.3410\/B3-15"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1016\/j.jprot.2010.06.006"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1007\/s12264-016-0092-z"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4939-3999-2_3"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1074\/JBC.R116.757955"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.3389\/fnmol.2019.00240"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.12998\/wjcc.v7.i2.171"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2015.03.033"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.17352\/aadc.000012"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.3389\/fchem.2021.734280"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1016\/j.jadr.2020.100003"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.3390\/PROTEOMES7020017"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1016\/j.ebiom.2019.06.021"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1002\/prca.201400114"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1007\/s00018-022-04256-8"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1101\/2022.06.03.487443"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1016\/j.saa.2024.125236"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1364\/BOE.9.004175"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.3233\/JAD-191034"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrep.2020.100888"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.5478\/MSL.2021.12.3.93"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1039\/D1RA04305F"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1039\/D1RA04305F"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.30491\/jabr.2023.380590.1595"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-019-50195-z"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.1117\/12.2051759"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.1021\/acs.chemrev.7b00668"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.1016\/j.colsurfb.2024.113824"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.1021\/acs.analchem.3c00026"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.3c11370"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.3390\/genes13081342"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-020-68598-8"},{"key":"ref46\/cit46","doi-asserted-by":"publisher","DOI":"10.1021\/acssensors.0c00444"},{"key":"ref47\/cit47","doi-asserted-by":"publisher","DOI":"10.1002\/adom.202203104"},{"key":"ref48\/cit48","doi-asserted-by":"publisher","DOI":"10.1016\/j.snb.2022.131568"},{"key":"ref49\/cit49","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.9b04001"},{"key":"ref50\/cit50","doi-asserted-by":"publisher","DOI":"10.1016\/j.saa.2024.124189"},{"key":"ref51\/cit51","doi-asserted-by":"publisher","DOI":"10.1111\/cas.16106"},{"key":"ref52\/cit52","doi-asserted-by":"publisher","DOI":"10.1021\/jp106666t"},{"key":"ref53\/cit53","doi-asserted-by":"publisher","DOI":"10.1002\/mus.25015"},{"key":"ref54\/cit54","doi-asserted-by":"publisher","DOI":"10.1021\/acschemneuro.0c00794"},{"key":"ref55\/cit55","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1703556114"},{"key":"ref56\/cit56","doi-asserted-by":"publisher","DOI":"10.3233\/JND-190457"},{"key":"ref57\/cit57","doi-asserted-by":"publisher","DOI":"10.1038\/s41419-023-06103-5"},{"key":"ref58\/cit58","doi-asserted-by":"publisher","DOI":"10.1155\/2012\/686183"},{"key":"ref59\/cit59","doi-asserted-by":"publisher","DOI":"10.1152\/japplphysiol.00248.2021"},{"key":"ref60\/cit60","doi-asserted-by":"publisher","DOI":"10.1155\/2014\/965631"},{"key":"ref61\/cit61","doi-asserted-by":"publisher","DOI":"10.1203\/00006450-198112000-00004"},{"key":"ref62\/cit62","doi-asserted-by":"publisher","DOI":"10.1159\/000115586"},{"key":"ref63\/cit63","doi-asserted-by":"publisher","DOI":"10.1159\/000153299"},{"key":"ref64\/cit64","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-7793.2001.00597.x"},{"key":"ref65\/cit65","doi-asserted-by":"publisher","DOI":"10.1038\/nbt.4148"},{"key":"ref66\/cit66","doi-asserted-by":"publisher","DOI":"10.1126\/sciadv.abg4910"},{"key":"ref67\/cit67","doi-asserted-by":"publisher","DOI":"10.3390\/antiox12040871"},{"key":"ref68\/cit68","doi-asserted-by":"publisher","DOI":"10.1093\/glycob\/cwy058"},{"key":"ref69\/cit69","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.121.054204"},{"key":"ref70\/cit70","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0089277"},{"key":"ref71\/cit71","doi-asserted-by":"publisher","DOI":"10.1007\/s00726-010-0715-z"},{"key":"ref72\/cit72","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1105734108"},{"key":"ref73\/cit73","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-019-41800-2"},{"key":"ref74\/cit74","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbamem.2020.183490"},{"key":"ref75\/cit75","doi-asserted-by":"publisher","DOI":"10.1021\/la00010a021"},{"key":"ref76\/cit76","doi-asserted-by":"publisher","DOI":"10.1021\/j100214a025"}],"container-title":["ACS Omega"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsomega.5c00838","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsomega.5c00838","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,29]],"date-time":"2025-04-29T08:13:39Z","timestamp":1745914419000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acsomega.5c00838"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,3,24]]},"references-count":76,"journal-issue":{"issue":"16","published-print":{"date-parts":[[2025,4,29]]}},"alternative-id":["10.1021\/acsomega.5c00838"],"URL":"https:\/\/doi.org\/10.1021\/acsomega.5c00838","relation":{},"ISSN":["2470-1343","2470-1343"],"issn-type":[{"value":"2470-1343","type":"print"},{"value":"2470-1343","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,3,24]]}}}