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Ceramic perovskites, characterized by their unique crystal structure, exhibit remarkable properties that make them highly suitable for technological applications. In this study, we explore the synergistic combination of two zirconium-based ceramic perovskites\ue5f8barium zirconate (BaZrO3) and strontium zirconate (SrZrO3)\ue5f8for the development of a photoelectrochemical platform designed to detect DPE. A fluorine-doped tin oxide (FTO) electrode was modified with materials based on BaZrO3 and SrZrO3 to create a highly efficient photoelectrochemical sensor. The combination of these materials significantly enhanced the sensor\u2019s performance compared to their individual use, facilitating faster electron transfer rates and improved sensitivity for DPE detection. A low-power LED lamp served as the light source, ensuring energy efficiency. The materials were synthesized by microwave-assisted combustion and thoroughly characterized using X-ray diffraction (XRD), Fourier-transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM), energy-dispersive X-ray spectroscopy (EDS), and chronoamperometry. Under optimized conditions, the sensor demonstrated two linear detection ranges for DPE: 0.01 to 100 \u03bcmol L\u20131 and 100 to 500 \u03bcmol L\u20131, with a detection limit of 0.009 \u03bcmol L\u20131. The modified platform (SrZrO3\/BaZrO3\/FTO) exhibited exceptional precision, accuracy, and selectivity for DPE detection. Furthermore, the method was successfully applied to determine DPE concentrations in artificial plasma samples, achieving recovery rates between 98.32 and 102.13%. These results highlight the promising character of this photoelectrochemical platform for reliable and sensitive DPE detection in real-world applications.<\/jats:p>","DOI":"10.1021\/acsomega.5c02185","type":"journal-article","created":{"date-parts":[[2025,7,4]],"date-time":"2025-07-04T04:54:47Z","timestamp":1751604887000},"page":"29256-29266","source":"Crossref","is-referenced-by-count":2,"title":["Ceramic Perovskite-Based\nPhotoelectrochemical Platform\nfor 2\u2011(3,4-Dihydroxyphenyl)ethylamine Detection with Enhanced\nSensitivity"],"prefix":"10.1021","volume":"10","author":[{"given":"Lenilda\nFerreira","family":"Costa","sequence":"first","affiliation":[{"name":"Federal University of Maranha\u0303o , , , ,","place":["Sa\u0303o Lui\u0301s, MA, Brazil, 65080-805"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jose\u0301 Ribamar Nascimento dos","family":"Santos","sequence":"additional","affiliation":[{"name":"Federal University of Maranha\u0303o , , , ,","place":["Sa\u0303o Lui\u0301s, MA, Brazil, 65080-805"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jefferson Santos","family":"Oliveira","sequence":"additional","affiliation":[{"name":"Science and Technology of Maranha\u0303o , , ,","place":["Sa\u0303o\nLui\u0301s, MA,, Brazil, 65030-005"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8817-0156","authenticated-orcid":true,"given":"Alan Silva","family":"de Menezes","sequence":"additional","affiliation":[{"name":"Federal University of Maranha\u0303o , , ,","place":["Sa\u0303o Lui\u0301s, MA,, Brazil, 65080-805"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gilvan Pereira\nde","family":"Figueredo","sequence":"additional","affiliation":[{"name":"Science and Technology of Maranha\u0303o , , ,","place":["Sa\u0303o\nLui\u0301s, MA,, Brazil, 65030-005"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9465-6427","authenticated-orcid":true,"given":"Fla\u0301vio Santos","family":"Damos","sequence":"additional","affiliation":[{"name":"Federal University of Maranha\u0303o , , , ,","place":["Sa\u0303o Lui\u0301s, MA, Brazil, 65080-805"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2972-4104","authenticated-orcid":true,"given":"Rita de Ca\u0301ssia Silva","family":"Luz","sequence":"additional","affiliation":[{"name":"Federal University of Maranha\u0303o , , , ,","place":["Sa\u0303o Lui\u0301s, MA, Brazil, 65080-805"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2025,7,4]]},"reference":[{"key":"2026081812130645900_cit1","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1080\/10408347.2024.2324460","article-title":"The role of\ncatecholamines in the pathogenesis of diseases and the modified electrodes\nfor electrochemical detection of catecholamines: a review","author":"Zhang","year":"2024","journal-title":"Crit. 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