{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T16:36:27Z","timestamp":1789230987935,"version":"build-2803163510"},"reference-count":55,"publisher":"American Chemical Society (ACS)","issue":"45","license":[{"start":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T00:00:00Z","timestamp":1762473600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100008351","name":"Universidad Sim?n Bol?var","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100008351","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003033","name":"Ministerio de Ciencia, Tecnolog?a e Innovaci?n","doi-asserted-by":"publisher","award":["125380763038"],"award-info":[{"award-number":["125380763038"]}],"id":[{"id":"10.13039\/501100003033","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003033","name":"Ministerio de Ciencia, Tecnolog?a e Innovaci?n","doi-asserted-by":"publisher","award":["125384467468"],"award-info":[{"award-number":["125384467468"]}],"id":[{"id":"10.13039\/501100003033","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Cl?nica de la Costa"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ACS Omega"],"published-print":{"date-parts":[[2025,11,18]]},"DOI":"10.1021\/acsomega.5c06978","type":"journal-article","created":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T18:27:08Z","timestamp":1762540028000},"page":"54357-54367","source":"Crossref","is-referenced-by-count":4,"title":["Gold Nanoparticles SERS in the Nephritis Diagnosis in Lupus Patients from Urine"],"prefix":"10.1021","volume":"10","author":[{"given":"Alberto Carlos","family":"Espinosa","sequence":"first","affiliation":[{"name":"Facultad de Ciencias B\u00e1sicas y Biom\u00e9dicas, Life Science Research Center","place":["Barranquilla, Colombia"]},{"name":"Universidad Sim\u00f3n Bol\u00edvar","place":["Barranquilla, Colombia"]},{"name":"Center of Pharmaceutical Research","place":["Barranquilla, Colombia"]},{"name":"Procaps Laboratories","place":["Barranquilla, Colombia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alejandra","family":"Rojo-Sanchez","sequence":"additional","affiliation":[{"name":"Facultad de Ciencias B\u00e1sicas y Biom\u00e9dicas, Life Science Research Center","place":["Barranquilla, Colombia"]},{"name":"Universidad Sim\u00f3n Bol\u00edvar","place":["Barranquilla, Colombia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ada","family":"Carmona-Martes","sequence":"additional","affiliation":[{"name":"Facultad de Ciencias B\u00e1sicas y Biom\u00e9dicas, Life Science Research Center","place":["Barranquilla, Colombia"]},{"name":"Universidad Sim\u00f3n Bol\u00edvar","place":["Barranquilla, Colombia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Natally","family":"Vidal-Figueroa","sequence":"additional","affiliation":[{"name":"Facultad de Ciencias B\u00e1sicas y Biom\u00e9dicas, Life Science Research Center","place":["Barranquilla, Colombia"]},{"name":"Universidad Sim\u00f3n Bol\u00edvar","place":["Barranquilla, Colombia"]},{"name":"ALERT DHS Center of Excellence for Explosives Research, Department of Chemistry","place":["Mayag\u00fcez, United States"]},{"name":"University of Puerto Rico-Mayag\u00fcez Campus","place":["Mayag\u00fcez, United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antony A.","family":"Cardozo-Puello","sequence":"additional","affiliation":[{"name":"Facultad de Ciencias B\u00e1sicas y Biom\u00e9dicas, Life Science Research Center","place":["Barranquilla, Colombia"]},{"name":"Universidad Sim\u00f3n Bol\u00edvar","place":["Barranquilla, Colombia"]},{"name":"ALERT DHS Center of Excellence for Explosives Research, Department of Chemistry","place":["Mayag\u00fcez, United States"]},{"name":"University of Puerto Rico-Mayag\u00fcez Campus","place":["Mayag\u00fcez, United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lisandro","family":"Pacheco-Lugo","sequence":"additional","affiliation":[{"name":"Facultad de Ciencias B\u00e1sicas y Biom\u00e9dicas, Life Science Research Center","place":["Barranquilla, Colombia"]},{"name":"Universidad Sim\u00f3n Bol\u00edvar","place":["Barranquilla, Colombia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elkin","family":"Navarro Quiroz","sequence":"additional","affiliation":[{"name":"Facultad de Ciencias B\u00e1sicas y Biom\u00e9dicas, Life Science Research Center","place":["Barranquilla, Colombia"]},{"name":"Universidad Sim\u00f3n Bol\u00edvar","place":["Barranquilla, Colombia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eloina","family":"Zarate-Pe\u00f1ata","sequence":"additional","affiliation":[{"name":"Facultad de Ciencias B\u00e1sicas y Biom\u00e9dicas, Life Science Research Center","place":["Barranquilla, Colombia"]},{"name":"Universidad Sim\u00f3n Bol\u00edvar","place":["Barranquilla, Colombia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lorena G\u00f3mez","family":"Escocia","sequence":"additional","affiliation":[{"name":"Nephrology Department, De La Costa Clinic","place":["Barranquilla, Colombia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nataly J.","family":"Gal\u00e1n-Freyle","sequence":"additional","affiliation":[{"name":"Facultad de Ciencias B\u00e1sicas y Biom\u00e9dicas, Life Science Research Center","place":["Barranquilla, Colombia"]},{"name":"Universidad Sim\u00f3n Bol\u00edvar","place":["Barranquilla, Colombia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samuel P.","family":"Hern\u00e1ndez-Rivera","sequence":"additional","affiliation":[{"name":"ALERT DHS Center of Excellence for Explosives Research, Department of Chemistry","place":["Mayag\u00fcez, United States"]},{"name":"University of Puerto Rico-Mayag\u00fcez Campus","place":["Mayag\u00fcez, United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joe","family":"Villa-Medina","sequence":"additional","affiliation":[{"name":"Center of Pharmaceutical Research","place":["Barranquilla, Colombia"]},{"name":"Procaps Laboratories","place":["Barranquilla, Colombia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gustavo","family":"Aroca-Martinez","sequence":"additional","affiliation":[{"name":"Nephrology Department, De La Costa Clinic","place":["Barranquilla, Colombia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elvin S.","family":"Lebron-Ramirez","sequence":"additional","affiliation":[{"name":"ALERT DHS Center of Excellence for Explosives Research, Department of Chemistry","place":["Mayag\u00fcez, United States"]},{"name":"University of Puerto Rico-Mayag\u00fcez Campus","place":["Mayag\u00fcez, United States"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8919-2066","authenticated-orcid":true,"given":"Maximiliano","family":"M\u00e9ndez-L\u00f3pez","sequence":"additional","affiliation":[{"name":"Grupo de Qu\u00edmica y Biolog\u00eda, Departamento de Qu\u00edmica y Biolog\u00eda, Universidad Del Norte, Km 5 V\u00eda Puerto Colombia, 080001 Barranquilla, Colombia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5770-3706","authenticated-orcid":true,"given":"Leonardo C.","family":"Pacheco-Londo\u00f1o","sequence":"additional","affiliation":[{"name":"Facultad de Ciencias B\u00e1sicas y Biom\u00e9dicas, Life Science Research Center","place":["Barranquilla, Colombia"]},{"name":"Universidad Sim\u00f3n Bol\u00edvar","place":["Barranquilla, Colombia"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2025,11,7]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1038\/nrg2571"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1002\/art.24136"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1155\/2012\/849684"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1038\/srep35309"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.3390\/bios13010112"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1177\/0961203318812679"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0187973"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1016\/j.kint.2016.08.021"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0073076"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-025-97351-2"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-017-04774-7"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.3390\/molecules25204725"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2022.853778"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1136\/lupus-2015-000123"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1002\/prca.201500075"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-024-53679-9"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-024-60217-0"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1007\/s11356-023-26136-9"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.3390\/molecules30091876"},{"key":"ref20\/cit20","volume-title":"Bioconjugate Techniques","author":"Hermanson G. T.","year":"2013","edition":"3"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodchem.2021.131072"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-018-30407-8"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0080940"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1016\/j.saa.2004.11.017"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1016\/j.gie.2013.05.028"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1002\/jbio.202000275"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1039\/b304992b"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1002\/jrs.882"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bjc.6603102"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1364\/BOE.406097"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1080\/05704928.2014.923902"},{"key":"ref32\/cit32","volume-title":"Biocompatible Single-Walled Carbon Nanotubes in Mice Probed by Raman Spectroscopy","author":"Liu Z.","year":"2008"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1117\/1.3251053"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1002\/9780470027325.s8107"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1667\/0033-7587(2002)157[0175:TRSFTS]2.0.CO;2"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1002\/jemt.20229"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1529\/biophysj.105.066761"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1039\/C1AN15821J"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.1016\/j.jphotobiol.2017.09.019"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.1109\/TBME.2004.831538"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.1002\/jbio.201500109"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.1117\/12.2255878"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2010.10.027"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.1002\/jrs.1107"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.3390\/diagnostics10030141"},{"key":"ref46\/cit46","doi-asserted-by":"publisher","DOI":"10.1016\/j.vibspec.2005.02.013"},{"key":"ref47\/cit47","doi-asserted-by":"publisher","DOI":"10.1002\/lsm.10084"},{"issue":"1","key":"ref48\/cit48","doi-asserted-by":"crossref","first-page":"52","DOI":"10.31260\/RepertMedCir.v19.n1.2010.571","volume":"19","author":"Chaves W. G. S.","year":"2010","journal-title":"Repert. Med. Cir."},{"key":"ref49\/cit49","doi-asserted-by":"publisher","DOI":"10.1007\/s13555-020-00471-y"},{"key":"ref50\/cit50","doi-asserted-by":"publisher","DOI":"10.21203\/rs.3.rs-2080559\/v1"},{"key":"ref51\/cit51","doi-asserted-by":"publisher","DOI":"10.1039\/b909714g"},{"key":"ref52\/cit52","doi-asserted-by":"publisher","DOI":"10.1021\/bm0497116"},{"key":"ref53\/cit53","doi-asserted-by":"publisher","DOI":"10.1002\/masy.201550312"},{"key":"ref54\/cit54","unstructured":"Wise, B. M.; Shaver, J. M.; Gallagher, N. B.; Rasmus, W. W.; Koch, B. R. S. Continuum Parameter Number of LVs PRESS Chemometrics Tutorial for PLS_Toolbox and Solo."},{"key":"ref55\/cit55","doi-asserted-by":"publisher","DOI":"10.1186\/s12859-019-3310-7"}],"container-title":["ACS Omega"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsomega.5c06978","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsomega.5c06978","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,18]],"date-time":"2025-11-18T09:49:15Z","timestamp":1763459355000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acsomega.5c06978"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11,7]]},"references-count":55,"journal-issue":{"issue":"45","published-print":{"date-parts":[[2025,11,18]]}},"alternative-id":["10.1021\/acsomega.5c06978"],"URL":"https:\/\/doi.org\/10.1021\/acsomega.5c06978","relation":{},"ISSN":["2470-1343","2470-1343"],"issn-type":[{"value":"2470-1343","type":"print"},{"value":"2470-1343","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,11,7]]}}}