{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,17]],"date-time":"2026-02-17T11:36:05Z","timestamp":1771328165515,"version":"3.50.1"},"reference-count":46,"publisher":"American Chemical Society (ACS)","issue":"6","license":[{"start":{"date-parts":[[2026,2,5]],"date-time":"2026-02-05T00:00:00Z","timestamp":1770249600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100008868","name":"Jiangsu Provincial Department of Science and Technology","doi-asserted-by":"publisher","award":["BK20221169"],"award-info":[{"award-number":["BK20221169"]}],"id":[{"id":"10.13039\/501100008868","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81672002"],"award-info":[{"award-number":["81672002"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82503326"],"award-info":[{"award-number":["82503326"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100008832","name":"Nanjing Municipal Health Bureau","doi-asserted-by":"publisher","award":["ZKX20021"],"award-info":[{"award-number":["ZKX20021"]}],"id":[{"id":"10.13039\/501100008832","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Jiangsu Province Center for Innovation in Obstetrics and Gynecology","award":["CXZX202229"],"award-info":[{"award-number":["CXZX202229"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ACS Omega"],"published-print":{"date-parts":[[2026,2,17]]},"DOI":"10.1021\/acsomega.5c07289","type":"journal-article","created":{"date-parts":[[2026,2,5]],"date-time":"2026-02-05T18:17:44Z","timestamp":1770315464000},"page":"9090-9097","source":"Crossref","is-referenced-by-count":0,"title":["Transplacental Transfer of Telbivudine in Hepatitis B Virus-Infected Pregnant Women Treated with Telbivudine during the Third Trimester"],"prefix":"10.1021","volume":"11","author":[{"given":"Wenjun","family":"Zhang","sequence":"first","affiliation":[{"name":"Department of Laboratory Medicine, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, and Jiangsu Key Laboratory for Molecular Medicine","place":["Nanjing, China"]},{"name":"Nanjing University","place":["Nanjing, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chenyu","family":"Xu","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Zhenjiang Fourth People\u2019s Hospital","place":["Zhenjiang, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Huaijun","family":"Zhu","sequence":"additional","affiliation":[{"name":"Department of Pharmacy, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School","place":["Nanjing, China"]},{"name":"Nanjing University","place":["Nanjing, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yali","family":"Hu","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School","place":["Nanjing, China"]},{"name":"Nanjing University","place":["Nanjing, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yimin","family":"Dai","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School","place":["Nanjing, China"]},{"name":"Nanjing University","place":["Nanjing, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhaoping","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School","place":["Nanjing, China"]},{"name":"Nanjing University","place":["Nanjing, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Na","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Pharmacy, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School","place":["Nanjing, China"]},{"name":"Nanjing University","place":["Nanjing, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8880-0392","authenticated-orcid":true,"given":"Yi-Hua","family":"Zhou","sequence":"additional","affiliation":[{"name":"Department of Laboratory Medicine, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, and Jiangsu Key Laboratory for Molecular Medicine","place":["Nanjing, China"]},{"name":"Nanjing University","place":["Nanjing, China"]},{"name":"Department of Infectious Diseases, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School","place":["Nanjing, China"]},{"name":"Nanjing University","place":["Nanjing, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"316","published-online":{"date-parts":[[2026,2,5]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1038\/s41575-023-00760-9"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1097\/CM9.0000000000001791"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1016\/j.jve.2022.100076"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciaa898"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1080\/14760584.2021.1927723"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2017.07.013"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1007\/s12072-022-10412-w"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMc1805396"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1111\/jvh.12834"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1111\/apt.15321"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(20)30586-7"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1097\/FM9.0000000000000213"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1002\/hep.29800"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1055\/a-1630-7893"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1097\/FM9.0000000000000087"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1007\/s12072-021-10285-5"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1038\/s41591-023-02782-x"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1111\/apt.12538"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.14218\/JCTH.2022.00047"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1002\/hep.22885"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1002\/rmv.1849"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1007\/s12072-017-9839-5"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1016\/j.jinf.2017.05.012"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1155\/2019\/9046260"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1111\/jvh.12670"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1016\/j.dld.2018.07.030"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejogrb.2022.07.009"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1515\/mr-2022-0025"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.2165\/00003088-200443080-00001"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinthera.2007.12.032"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.3389\/fchem.2021.714678"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1021\/acs.estlett.4c00413"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1109\/access.2023.3272987"},{"key":"ref34\/cit34","unstructured":"FDA (2015). Analytical Procedures\nand Methods\nValidation for Drugs and Biologics. https:\/\/www.fda.gov\/regulatory-information\/search-fda-guidance-documents\/analytical-procedures-and-methods-validation-drugs-and-biologics (Accessed December 22, 2025)."},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1016\/j.jchromb.2013.05.008"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1016\/j.jchromb.2019.121925"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1021\/acsomega.0c04197"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1007\/s40262-014-0185-7"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.50.3.874-879.2006"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.3851\/IMP1918"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.00557-07"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.1016\/j.dld.2018.11.003"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2024.22952"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.1111\/apt.70173"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.1056\/nejmoa2407001"},{"key":"ref46\/cit46","doi-asserted-by":"publisher","DOI":"10.1038\/nprot.2012.144"}],"container-title":["ACS Omega"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsomega.5c07289","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsomega.5c07289","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,2,17]],"date-time":"2026-02-17T10:30:05Z","timestamp":1771324205000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acsomega.5c07289"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,2,5]]},"references-count":46,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2026,2,17]]}},"alternative-id":["10.1021\/acsomega.5c07289"],"URL":"https:\/\/doi.org\/10.1021\/acsomega.5c07289","relation":{},"ISSN":["2470-1343","2470-1343"],"issn-type":[{"value":"2470-1343","type":"print"},{"value":"2470-1343","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,2,5]]}}}