{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T19:17:14Z","timestamp":1789154234174,"version":"build-2803163510"},"reference-count":47,"publisher":"American Chemical Society (ACS)","issue":"3","license":[{"start":{"date-parts":[[2026,1,10]],"date-time":"2026-01-10T00:00:00Z","timestamp":1768003200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100021171","name":"Basic and Applied Basic Research Foundation of Guangdong Province","doi-asserted-by":"publisher","award":["2021A1515110494"],"award-info":[{"award-number":["2021A1515110494"]}],"id":[{"id":"10.13039\/501100021171","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82301752"],"award-info":[{"award-number":["82301752"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Technology Innovation Strategy Special Foundation of Zhanjiang","award":["2023A01005"],"award-info":[{"award-number":["2023A01005"]}]},{"name":"Guangdong workstation, State Key Laboratory of Pathogenesis, Prevention and Treatment of High incidence Diseases in Central Asia","award":["SKL-HIDCA-2024-GD18"],"award-info":[{"award-number":["SKL-HIDCA-2024-GD18"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ACS Omega"],"published-print":{"date-parts":[[2026,1,27]]},"DOI":"10.1021\/acsomega.5c08903","type":"journal-article","created":{"date-parts":[[2026,1,10]],"date-time":"2026-01-10T16:50:22Z","timestamp":1768063822000},"page":"4175-4187","source":"Crossref","is-referenced-by-count":2,"title":["Universal Smartphone-Assisted Colorimetric Quantitative Platform Based on CRISPR Cas12a Detection for Sensitive and Rapid Diagnosis of Multiple Virulence Genes of Hypervirulent\n                    <i>Klebsiella pneumoniae<\/i>"],"prefix":"10.1021","volume":"11","author":[{"given":"Zixuan","family":"Huang","sequence":"first","affiliation":[{"name":"Dongguan Key Laboratory of Stem Cell and Regenerative Tissue Engineering, School of Basic Medicine, The First Dongguan Affiliated Hospital","place":["Dongguan, China"]},{"name":"Guangdong Medical University","place":["Dongguan, China"]},{"name":"Zhanjiang Key Laboratory of Human Microecology and Clinical Translation Research, The Marine Biomedical Research Institute, School of Ocean and Tropical Medicine","place":["Zhanjiang, China"]},{"name":"Guangdong Medical University","place":["Zhanjiang, China"]},{"name":"Guangdong Key Laboratory of Age-Related Cardiac and Cerebral Diseases","place":["Zhanjiang, China"]},{"name":"Affiliated Hospital of Guangdong Medical University","place":["Zhanjiang, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenbo","family":"Tang","sequence":"additional","affiliation":[{"name":"Dongguan Key Laboratory of Stem Cell and Regenerative Tissue Engineering, School of Basic Medicine, The First Dongguan Affiliated Hospital","place":["Dongguan, China"]},{"name":"Guangdong Medical University","place":["Dongguan, China"]},{"name":"Zhanjiang Key Laboratory of Human Microecology and Clinical Translation Research, The Marine Biomedical Research Institute, School of Ocean and Tropical Medicine","place":["Zhanjiang, China"]},{"name":"Guangdong Medical University","place":["Zhanjiang, China"]},{"name":"Guangdong Key Laboratory of Age-Related Cardiac and Cerebral Diseases","place":["Zhanjiang, China"]},{"name":"Affiliated Hospital of Guangdong Medical University","place":["Zhanjiang, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shaohua","family":"Tan","sequence":"additional","affiliation":[{"name":"Dongguan Key Laboratory of Stem Cell and Regenerative Tissue Engineering, School of Basic Medicine, The First Dongguan Affiliated Hospital","place":["Dongguan, China"]},{"name":"Guangdong Medical University","place":["Dongguan, China"]},{"name":"Zhanjiang Key Laboratory of Human Microecology and Clinical Translation Research, The Marine Biomedical Research Institute, School of Ocean and Tropical Medicine","place":["Zhanjiang, China"]},{"name":"Guangdong Medical University","place":["Zhanjiang, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peihua","family":"Tang","sequence":"additional","affiliation":[{"name":"Dongguan Key Laboratory of Stem Cell and Regenerative Tissue Engineering, School of Basic Medicine, The First Dongguan Affiliated Hospital","place":["Dongguan, China"]},{"name":"Guangdong Medical University","place":["Dongguan, China"]},{"name":"Zhanjiang Key Laboratory of Human Microecology and Clinical Translation Research, The Marine Biomedical Research Institute, School of Ocean and Tropical Medicine","place":["Zhanjiang, China"]},{"name":"Guangdong Medical University","place":["Zhanjiang, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jingzhen","family":"Wu","sequence":"additional","affiliation":[{"name":"Dongguan Key Laboratory of Stem Cell and Regenerative Tissue Engineering, School of Basic Medicine, The First Dongguan Affiliated Hospital","place":["Dongguan, China"]},{"name":"Guangdong Medical University","place":["Dongguan, China"]},{"name":"Zhanjiang Key Laboratory of Human Microecology and Clinical Translation Research, The Marine Biomedical Research Institute, School of Ocean and Tropical Medicine","place":["Zhanjiang, China"]},{"name":"Guangdong Medical University","place":["Zhanjiang, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xin","family":"Liu","sequence":"additional","affiliation":[{"name":"Dongguan Key Laboratory of Stem Cell and Regenerative Tissue Engineering, School of Basic Medicine, The First Dongguan Affiliated Hospital","place":["Dongguan, China"]},{"name":"Guangdong Medical University","place":["Dongguan, China"]},{"name":"Zhanjiang Key Laboratory of Human Microecology and Clinical Translation Research, The Marine Biomedical Research Institute, School of Ocean and Tropical Medicine","place":["Zhanjiang, China"]},{"name":"Guangdong Medical University","place":["Zhanjiang, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junda","family":"Luo","sequence":"additional","affiliation":[{"name":"School of Biomedical Engineering","place":["Dongguan, China"]},{"name":"Guangdong Medical University","place":["Dongguan, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simin","family":"Peng","sequence":"additional","affiliation":[{"name":"School of Biomedical Engineering","place":["Dongguan, China"]},{"name":"Guangdong Medical University","place":["Dongguan, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhenqi","family":"Wan","sequence":"additional","affiliation":[{"name":"School of Biomedical Engineering","place":["Dongguan, China"]},{"name":"Guangdong Medical University","place":["Dongguan, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miaoyun","family":"Wu","sequence":"additional","affiliation":[{"name":"Dongguan Key Laboratory of Stem Cell and Regenerative Tissue Engineering, School of Basic Medicine, The First Dongguan Affiliated Hospital","place":["Dongguan, China"]},{"name":"Guangdong Medical University","place":["Dongguan, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peilin","family":"Gu","sequence":"additional","affiliation":[{"name":"Dongguan Key Laboratory of Stem Cell and Regenerative Tissue Engineering, School of Basic Medicine, The First Dongguan Affiliated Hospital","place":["Dongguan, China"]},{"name":"Guangdong Medical University","place":["Dongguan, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tengjun","family":"Li","sequence":"additional","affiliation":[{"name":"Dongguan Key Laboratory of Stem Cell and Regenerative Tissue Engineering, School of Basic Medicine, The First Dongguan Affiliated Hospital","place":["Dongguan, China"]},{"name":"Guangdong Medical University","place":["Dongguan, China"]},{"name":"Zhanjiang Key Laboratory of Human Microecology and Clinical Translation Research, The Marine Biomedical Research Institute, School of Ocean and Tropical Medicine","place":["Zhanjiang, China"]},{"name":"Guangdong Medical University","place":["Zhanjiang, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zuguo","family":"Zhao","sequence":"additional","affiliation":[{"name":"Dongguan Key Laboratory of Stem Cell and Regenerative Tissue Engineering, School of Basic Medicine, The First Dongguan Affiliated Hospital","place":["Dongguan, China"]},{"name":"Guangdong Medical University","place":["Dongguan, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yingying","family":"Liang","sequence":"additional","affiliation":[{"name":"Dongguan Key Laboratory of Stem Cell and Regenerative Tissue Engineering, School of Basic Medicine, The First Dongguan Affiliated Hospital","place":["Dongguan, China"]},{"name":"Guangdong Medical University","place":["Dongguan, China"]},{"name":"The Southeast General Hospital of Dongguan, The First Dongguan Affiliated Hospital of Guangdong Medical University","place":["Dongguan, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenying","family":"Luo","sequence":"additional","affiliation":[{"name":"Guangdong Key Laboratory of Age-Related Cardiac and Cerebral Diseases","place":["Zhanjiang, China"]},{"name":"Affiliated Hospital of Guangdong Medical University","place":["Zhanjiang, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sha","family":"Ma","sequence":"additional","affiliation":[{"name":"School of Biomedical Engineering","place":["Dongguan, China"]},{"name":"Guangdong Medical University","place":["Dongguan, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1398-8313","authenticated-orcid":true,"given":"Xuemeng","family":"Li","sequence":"additional","affiliation":[{"name":"Dongguan Key Laboratory of Stem Cell and Regenerative Tissue Engineering, School of Basic Medicine, The First Dongguan Affiliated Hospital","place":["Dongguan, China"]},{"name":"Guangdong Medical University","place":["Dongguan, China"]},{"name":"Zhanjiang Key Laboratory of Human Microecology and Clinical Translation Research, The Marine Biomedical Research Institute, School of Ocean and Tropical Medicine","place":["Zhanjiang, China"]},{"name":"Guangdong Medical University","place":["Zhanjiang, China"]},{"name":"Guangdong Key Laboratory of Age-Related Cardiac and Cerebral Diseases","place":["Zhanjiang, China"]},{"name":"Affiliated Hospital of Guangdong Medical University","place":["Zhanjiang, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2026,1,10]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jksus.2024.103284"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1186\/s12866-023-03022-5"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1016\/j.scib.2023.09.040"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1128\/jcm.00776-18"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1099\/mic.0.050336-0"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1186\/s12941-022-00514-6"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1021\/acs.biochem.6b00409"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.00093-17"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1016\/j.bios.2022.114167"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1016\/j.snb.2023.134278"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1016\/j.talanta.2023.125039"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1021\/acsomega.4c03911"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1021\/acsomega.4c03413"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1021\/acs.analchem.3c03753"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1016\/j.talanta.2022.124220"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1016\/j.talanta.2023.125202"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1021\/acsomega.5c00479"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2023.1128261"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1016\/j.talanta.2022.123276"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1128\/spectrum.01329-23"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.2147\/IDR.S348456"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1080\/22221751.2020.1763857"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1128\/spectrum.03984-22"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1016\/j.bios.2021.113682"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1016\/j.snb.2023.134509"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1016\/j.cca.2023.117741"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.3390\/s23115053"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1021\/acssensors.3c00031"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1021\/acsomega.5c03564"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.3390\/s23239391"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1016\/j.snb.2022.131871"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1016\/j.talanta.2024.126119"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1038\/s41587-021-00950-3"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.1989.00390060171048"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1186\/s12866-023-03124-0"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1016\/j.micres.2024.127839"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2024.1356229"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1080\/22221751.2022.2049458"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.1186\/s12866-024-03465-4"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.20411\/pai.v10i1.777"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2020.01189"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.1111\/joim.13007"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-025-57379-4"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.1016\/j.diagmicrobio.2025.116684"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.7717\/peerj.20198"},{"key":"ref46\/cit46","doi-asserted-by":"publisher","DOI":"10.2147\/IDR.S534490"},{"key":"ref47\/cit47","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2015.01435"}],"container-title":["ACS Omega"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsomega.5c08903","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsomega.5c08903","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,27]],"date-time":"2026-01-27T09:49:53Z","timestamp":1769507393000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acsomega.5c08903"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1,10]]},"references-count":47,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2026,1,27]]}},"alternative-id":["10.1021\/acsomega.5c08903"],"URL":"https:\/\/doi.org\/10.1021\/acsomega.5c08903","relation":{},"ISSN":["2470-1343","2470-1343"],"issn-type":[{"value":"2470-1343","type":"print"},{"value":"2470-1343","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1,10]]}}}