{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T12:35:03Z","timestamp":1771504503186,"version":"3.50.1"},"reference-count":49,"publisher":"American Chemical Society (ACS)","issue":"1","license":[{"start":{"date-parts":[[2025,12,19]],"date-time":"2025-12-19T00:00:00Z","timestamp":1766102400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100012245","name":"Science and Technology Planning Project of Guangdong Province","doi-asserted-by":"publisher","award":["2023B1111030006"],"award-info":[{"award-number":["2023B1111030006"]}],"id":[{"id":"10.13039\/501100012245","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100021171","name":"Basic and Applied Basic Research Foundation of Guangdong Province","doi-asserted-by":"publisher","award":["2025A1515012605"],"award-info":[{"award-number":["2025A1515012605"]}],"id":[{"id":"10.13039\/501100021171","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100006469","name":"Fundo para o Desenvolvimento das Ci?ncias e da Tecnologia","doi-asserted-by":"publisher","award":["0090\/2022\/A"],"award-info":[{"award-number":["0090\/2022\/A"]}],"id":[{"id":"10.13039\/501100006469","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82373166"],"award-info":[{"award-number":["82373166"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82573325"],"award-info":[{"award-number":["82573325"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Guangzhou Health Technology Project","award":["20241A011112"],"award-info":[{"award-number":["20241A011112"]}]},{"name":"Science and Technology Projects in Nansha District","award":["2023MS006"],"award-info":[{"award-number":["2023MS006"]}]},{"name":"Huadu District People?s Hospital of Guangzhou Internal Research Fund Project","award":["2022C01"],"award-info":[{"award-number":["2022C01"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ACS Omega"],"published-print":{"date-parts":[[2026,1,13]]},"DOI":"10.1021\/acsomega.5c09311","type":"journal-article","created":{"date-parts":[[2025,12,19]],"date-time":"2025-12-19T05:06:51Z","timestamp":1766120811000},"page":"1557-1574","source":"Crossref","is-referenced-by-count":1,"title":["Integrating Proteomics and Predictive Model: Elucidating the Role of Aminated Nanodiamonds in Suppressing Prostate Cancer Growth"],"prefix":"10.1021","volume":"11","author":[{"given":"Wenjie","family":"Xie","sequence":"first","affiliation":[{"name":"Department of Urology, the Second Affiliated Hospital, School of Medicine","place":["Guangzhou, China"]},{"name":"South China University of Technology","place":["Guangzhou, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qianfeng","family":"Xu","sequence":"additional","affiliation":[{"name":"Department of Urology, the Second Affiliated Hospital, School of Medicine","place":["Guangzhou, China"]},{"name":"South China University of Technology","place":["Guangzhou, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zeheng","family":"Tan","sequence":"additional","affiliation":[{"name":"Department of Urology, the Second Affiliated Hospital, School of Medicine","place":["Guangzhou, China"]},{"name":"South China University of Technology","place":["Guangzhou, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7068-2172","authenticated-orcid":true,"given":"Jundong","family":"Lin","sequence":"additional","affiliation":[{"name":"Guangdong Provincial Key Laboratory of Urology, the First Affiliated Hospital of Guangzhou Medical University","place":["Guangzhou, China"]},{"name":"Guangzhou Medical University","place":["Guangzhou, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fen","family":"Zou","sequence":"additional","affiliation":[{"name":"Department of Urology, the Second Affiliated Hospital, School of Medicine","place":["Guangzhou, China"]},{"name":"South China University of Technology","place":["Guangzhou, China"]},{"name":"Department of Urology, Guangdong Key Laboratory of Clinical Molecular Medicine and Diagnostics, Guangzhou First People\u2019s Hospital, School of Medicine","place":["Guangzhou, China"]},{"name":"South China University of Technology","place":["Guangzhou, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Muqi","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Urology, the Second Affiliated Hospital, School of Medicine","place":["Guangzhou, China"]},{"name":"South China University of Technology","place":["Guangzhou, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiaquan","family":"Xu","sequence":"additional","affiliation":[{"name":"Department of Urology, the Second Affiliated Hospital, School of Medicine","place":["Guangzhou, China"]},{"name":"South China University of Technology","place":["Guangzhou, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guowei","family":"Zhong","sequence":"additional","affiliation":[{"name":"Department of Urology, the Second Affiliated Hospital, School of Medicine","place":["Guangzhou, China"]},{"name":"South China University of Technology","place":["Guangzhou, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qiuling","family":"Du","sequence":"additional","affiliation":[{"name":"Department of Urology, the Second Affiliated Hospital, School of Medicine","place":["Guangzhou, China"]},{"name":"South China University of Technology","place":["Guangzhou, China"]},{"name":"Department of Urology, Guangdong Key Laboratory of Clinical Molecular Medicine and Diagnostics, Guangzhou First People\u2019s Hospital, School of Medicine","place":["Guangzhou, China"]},{"name":"South China University of Technology","place":["Guangzhou, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jinxiang","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Urology, the Second Affiliated Hospital, School of Medicine","place":["Guangzhou, China"]},{"name":"South China University of Technology","place":["Guangzhou, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jibiao","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Urology, the Second Affiliated Hospital, School of Medicine","place":["Guangzhou, China"]},{"name":"South China University of Technology","place":["Guangzhou, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Minyao","family":"Jiang","sequence":"additional","affiliation":[{"name":"Guangzhou Laboratory (No. 9 XingDaoHuanBei Road, Guangzhou International Bio Island)","place":["Guangzhou, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ming","family":"Xi","sequence":"additional","affiliation":[{"name":"Guangzhou Laboratory (No. 9 XingDaoHuanBei Road, Guangzhou International Bio Island)","place":["Guangzhou, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wei","family":"Hua","sequence":"additional","affiliation":[{"name":"Guangzhou Laboratory (No. 9 XingDaoHuanBei Road, Guangzhou International Bio Island)","place":["Guangzhou, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3061-7303","authenticated-orcid":true,"given":"Yangjia","family":"Zhuo","sequence":"additional","affiliation":[{"name":"Department of Urology, the Second Affiliated Hospital, School of Medicine","place":["Guangzhou, China"]},{"name":"South China University of Technology","place":["Guangzhou, China"]},{"name":"Department of Urology, Guangdong Key Laboratory of Clinical Molecular Medicine and Diagnostics, Guangzhou First People\u2019s Hospital, School of Medicine","place":["Guangzhou, China"]},{"name":"South China University of Technology","place":["Guangzhou, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yixun","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Burn and Plastic Surgery, the Second Affiliated Hospital, School of Medicine","place":["Guangzhou, China"]},{"name":"South China University of Technology","place":["Guangzhou, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qishan","family":"Dai","sequence":"additional","affiliation":[{"name":"Department of Urology, the Second Affiliated Hospital, School of Medicine","place":["Guangzhou, China"]},{"name":"South China University of Technology","place":["Guangzhou, China"]},{"name":"Department of Urology, Guangdong Key Laboratory of Clinical Molecular Medicine and Diagnostics, Guangzhou First People\u2019s Hospital, School of Medicine","place":["Guangzhou, China"]},{"name":"South China University of Technology","place":["Guangzhou, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0430-2845","authenticated-orcid":true,"given":"Weide","family":"Zhong","sequence":"additional","affiliation":[{"name":"Department of Urology, the Second Affiliated Hospital, School of Medicine","place":["Guangzhou, China"]},{"name":"South China University of Technology","place":["Guangzhou, China"]},{"name":"Guangdong Provincial Key Laboratory of Urology, the First Affiliated Hospital of Guangzhou Medical University","place":["Guangzhou, China"]},{"name":"Guangzhou Medical University","place":["Guangzhou, China"]},{"name":"Department of Urology, Guangdong Key Laboratory of Clinical Molecular Medicine and Diagnostics, Guangzhou First People\u2019s Hospital, School of Medicine","place":["Guangzhou, China"]},{"name":"South China University of Technology","place":["Guangzhou, China"]},{"name":"Guangzhou Laboratory (No. 9 XingDaoHuanBei Road, Guangzhou International Bio Island)","place":["Guangzhou, China"]},{"name":"State Key Laboratory of Mechanism and Quality of Chinese Medicine","place":["Taipa, China"]},{"name":"Macau University of Science and Technology","place":["Taipa, China"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"316","published-online":{"date-parts":[[2025,12,19]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21820"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1016\/S2468-2667(23)00211-6"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21660"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2021.39.15_suppl.5003"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.3760\/cma.j.cn112152-20200313-00200"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1007\/978-981-10-7013-6_32"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1038\/s41585-018-0090-1"},{"key":"ref8\/cit8","doi-asserted-by":"crossref","unstructured":"Siegel, R. L.; Miller, K. D.; Jemal, A.Descriptive Epidemiology\n                      American Cancer Society\u2019s Principles of Oncology: Prevention to Survivorship\n                      2018, pp 1\u201314.","DOI":"10.1002\/9781119468868.ch1"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-med-051517-011947"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.3390\/cells8010043"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1021\/acs.chemrev.9b00099"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1016\/j.electacta.2010.01.099"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1016\/j.molliq.2019.111874"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1080\/25740881.2019.1587773"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1016\/j.slast.2023.03.007"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.2217\/nnm.13.183"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcis.2017.11.009"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1002\/smll.201902238"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.201102670"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1002\/smll.200902305"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1039\/c2nj40226b"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.201601207"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpha.2019.09.003"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-018-06749-2"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1016\/j.nano.2016.12.005"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.0c21332"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1016\/j.semcancer.2017.04.004"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1002\/pc.22480"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.3934\/mbe.2023450"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1016\/j.archoralbio.2020.104895"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1007\/s00296-014-3178-9"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1155\/2021\/7471291"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1039\/C6NR08315C"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1039\/c3nr04143c"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1016\/j.bpj.2015.11.3186"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.3390\/ijms17071111"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1049\/iet-smt.2018.5594"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1016\/j.diamond.2009.11.022"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2012.06.084"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.1016\/j.toxlet.2010.07.001"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.1021\/nn200986z"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2013.08.056"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcis.2023.05.103"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.1016\/j.actbio.2019.01.025"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.1002\/pssa.201600094"},{"key":"ref46\/cit46","doi-asserted-by":"publisher","DOI":"10.1002\/adfm.202111077"},{"key":"ref47\/cit47","doi-asserted-by":"publisher","DOI":"10.1016\/j.scitotenv.2024.171299"},{"key":"ref48\/cit48","doi-asserted-by":"publisher","DOI":"10.3390\/molecules24010152"},{"key":"ref49\/cit49","doi-asserted-by":"publisher","DOI":"10.1242\/dev.188714"}],"container-title":["ACS Omega"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsomega.5c09311","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsomega.5c09311","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,16]],"date-time":"2026-01-16T12:48:20Z","timestamp":1768567700000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acsomega.5c09311"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12,19]]},"references-count":49,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,1,13]]}},"alternative-id":["10.1021\/acsomega.5c09311"],"URL":"https:\/\/doi.org\/10.1021\/acsomega.5c09311","relation":{},"ISSN":["2470-1343","2470-1343"],"issn-type":[{"value":"2470-1343","type":"print"},{"value":"2470-1343","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,12,19]]}}}