{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,17]],"date-time":"2026-05-17T09:10:33Z","timestamp":1779009033102,"version":"3.51.4"},"reference-count":32,"publisher":"American Chemical Society (ACS)","issue":"18","license":[{"start":{"date-parts":[[2026,4,24]],"date-time":"2026-04-24T00:00:00Z","timestamp":1776988800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100004410","name":"T\u00fcrkiye Bilimsel ve Teknolojik Arastirma Kurumu","doi-asserted-by":"publisher","award":["217Z046"],"award-info":[{"award-number":["217Z046"]}],"id":[{"id":"10.13039\/501100004410","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004410","name":"T\u00fcrkiye Bilimsel ve Teknolojik Arastirma Kurumu","doi-asserted-by":"publisher","award":["221Z267"],"award-info":[{"award-number":["221Z267"]}],"id":[{"id":"10.13039\/501100004410","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ACS Omega"],"published-print":{"date-parts":[[2026,5,12]]},"DOI":"10.1021\/acsomega.6c02033","type":"journal-article","created":{"date-parts":[[2026,4,25]],"date-time":"2026-04-25T02:04:31Z","timestamp":1777082671000},"page":"27468-27480","source":"Crossref","is-referenced-by-count":0,"title":["Synthesis and Biological Evaluation of Modified Peptide Derivatives Targeting the SARS-CoV-2 Nsp3 Macrodomain (Mac1) Replication Domain"],"prefix":"10.1021","volume":"11","author":[{"given":"\u00d6zge","family":"\u00d6zmen","sequence":"first","affiliation":[{"name":"Bezmialem Vakif University","place":["Istanbul, T\u00fcrkiye"]},{"name":"Faculty of Pharmacy","place":["Istanbul, T\u00fcrkiye"]},{"name":"Kartal Dr. Lutfi Kirdar City Hospital","place":["Istanbul, T\u00fcrkiye"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bet\u00fcl","family":"Oru\u00e7o\u011flu","sequence":"additional","affiliation":[{"name":"Institute of Life Sciences and Biotechnology","place":["Istanbul, T\u00fcrkiye"]},{"name":"Bezmialem Vakif University","place":["Istanbul, T\u00fcrkiye"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Serap \u0130pek","family":"Dingi\u015f Birg\u00fcl","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Chemistry, Faculty of Pharmacy","place":["Istanbul, T\u00fcrkiye"]},{"name":"Bezmialem Vakif University","place":["Istanbul, T\u00fcrkiye"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dilek","family":"\u00d6zt\u00fcrk Civelek","sequence":"additional","affiliation":[{"name":"Department of Pharmacology, Faculty of Pharmacy","place":["Istanbul, T\u00fcrkiye"]},{"name":"Istanbul University -Cerrahpa\u015fa","place":["Istanbul, T\u00fcrkiye"]},{"name":"Department of Pharmacology, Faculty of Pharmacy","place":["Istanbul, T\u00fcrkiye"]},{"name":"Bezmialem Vakif University","place":["Istanbul, T\u00fcrkiye"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5613-1339","authenticated-orcid":true,"given":"\u015eeref","family":"G\u00fcl","sequence":"additional","affiliation":[{"name":"Institute of Life Sciences and Biotechnology","place":["Istanbul, T\u00fcrkiye"]},{"name":"Bezmialem Vakif University","place":["Istanbul, T\u00fcrkiye"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Atilla","family":"Akdemir","sequence":"additional","affiliation":[{"name":"Department of Pharmacology, Faculty of Pharmacy","place":["Istanbul, T\u00fcrkiye"]},{"name":"Istanbul Kent University","place":["Istanbul, T\u00fcrkiye"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fatih","family":"S\u00f6nmez","sequence":"additional","affiliation":[{"name":"Pamukova Vocational School","place":["Sakarya, T\u00fcrkiye"]},{"name":"Sakarya University of Applied Sciences","place":["Sakarya, T\u00fcrkiye"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4663-5402","authenticated-orcid":true,"given":"Belma","family":"Zengin Kurt","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Chemistry, Faculty of Pharmacy","place":["Istanbul, T\u00fcrkiye"]},{"name":"Bezmialem Vakif University","place":["Istanbul, T\u00fcrkiye"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"316","published-online":{"date-parts":[[2026,4,24]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1134\/S0006297922120215"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1016\/j.mcp.2024.101973"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1038\/s41579-021-00630-8"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1038\/s42003-020-01577-x"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1016\/j.antiviral.2017.11.001"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1128\/spectrum.02871-24"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1016\/j.pbiomolbio.2021.02.002"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1016\/j.drudis.2023.103832"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.3390\/pathogens12101221"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jmedchem.4c00656"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1038\/s42003-022-03613-4"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1126\/science.abl4784"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.3390\/biom13091339"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1016\/j.bmc.2022.116788"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1128\/mbio.03865-24"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-024-81711-5"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2212931120"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.3390\/pathogens12020324"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1039\/c3ob27458f"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1016\/j.tetlet.2020.152719"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1126\/sciadv.abf8711"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-025-88388-4"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1128\/jvi.01837-21"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.00687-21"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1080\/22221751.2020.1827985"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1016\/j.antiviral.2021.105209"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/28.1.235"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1038\/nsb1203-980"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1007\/s10822-013-9644-8"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jctc.1c00302"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1021\/jm0306430"},{"key":"ref32\/cit32","first-page":"43","volume-title":"Proceedings of the ACM\/IEEE SC2006 Conference on High Performance Networking and Computing","author":"Bowers K. J.","year":"2006"}],"container-title":["ACS Omega"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsomega.6c02033","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsomega.6c02033","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,17]],"date-time":"2026-05-17T08:58:42Z","timestamp":1779008322000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acsomega.6c02033"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4,24]]},"references-count":32,"journal-issue":{"issue":"18","published-print":{"date-parts":[[2026,5,12]]}},"alternative-id":["10.1021\/acsomega.6c02033"],"URL":"https:\/\/doi.org\/10.1021\/acsomega.6c02033","relation":{},"ISSN":["2470-1343","2470-1343"],"issn-type":[{"value":"2470-1343","type":"print"},{"value":"2470-1343","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,4,24]]}}}