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This transformation leverages the N-Cl moiety as a highly effective internal oxidant, enabling the reaction to proceed smoothly under mild conditions and delivering the target products in excellent yields (up to 98% yield). Control experiments further reveal the superior oxidizing ability of the N-Cl benzamide relative to its N-OMe and N-OPiv analogues. Notably, the reaction proceeds with 85% yield even at an exceptionally low catalyst loading of 0.05 mol %.<\/jats:p>","DOI":"10.1021\/acsomega.6c02975","type":"journal-article","created":{"date-parts":[[2026,7,11]],"date-time":"2026-07-11T01:45:32Z","timestamp":1783734332000},"page":"43782-43789","source":"Crossref","is-referenced-by-count":0,"title":["Rhodium-Catalyzed C\u2013H Activation\/Annulation\nof\n                    <i>N<\/i>\n                    -Chlorobenzamide Derivatives with Alkynes"],"prefix":"10.1021","volume":"11","author":[{"given":"Qing-Xin","family":"Jiang","sequence":"first","affiliation":[{"name":"Donghua University , , 2399 Guangfulin Lu , ,","place":["Shanghai, China, 201620"]},{"name":"Second Military Medical University (Naval Medical University) , , 325 Guohe Road , ,","place":["Shanghai, China, 200433"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ji-Chen","family":"Huang","sequence":"additional","affiliation":[{"name":"Second Military Medical University (Naval Medical University) , , 325 Guohe Road , ,","place":["Shanghai, China, 200433"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Teng-Bo","family":"Zhao","sequence":"additional","affiliation":[{"name":"Second Military Medical University (Naval Medical University) , , 325 Guohe Road , ,","place":["Shanghai, China, 200433"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pei-Chao","family":"Zhang","sequence":"additional","affiliation":[{"name":"Second Military Medical University (Naval Medical University) , , 325 Guohe Road , ,","place":["Shanghai, China, 200433"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiao-Bin","family":"Zhuo","sequence":"additional","affiliation":[{"name":"Second Military Medical University (Naval Medical University) , , 325 Guohe Road , ,","place":["Shanghai, China, 200433"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rong-Da","family":"Ren","sequence":"additional","affiliation":[{"name":"Second Military Medical University (Naval Medical University) , , 325 Guohe Road , ,","place":["Shanghai, China, 200433"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9688-9091","authenticated-orcid":true,"given":"Xiao-Yun","family":"Chai","sequence":"additional","affiliation":[{"name":"Second Military Medical University (Naval Medical University) , , 325 Guohe Road , ,","place":["Shanghai, China, 200433"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5266-7275","authenticated-orcid":true,"given":"Yan","family":"Zou","sequence":"additional","affiliation":[{"name":"Second Military Medical University (Naval Medical University) , , 325 Guohe Road , ,","place":["Shanghai, China, 200433"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhiyu","family":"Shao","sequence":"additional","affiliation":[{"name":"Donghua University , , 2399 Guangfulin Lu , ,","place":["Shanghai, China, 201620"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qing-Jie","family":"Zhao","sequence":"additional","affiliation":[{"name":"Second Military Medical University (Naval Medical University) , , 325 Guohe Road , ,","place":["Shanghai, China, 200433"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wen-Wen","family":"Zhang","sequence":"additional","affiliation":[{"name":"Second Military Medical University (Naval Medical University) , , 325 Guohe Road , ,","place":["Shanghai, China, 200433"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2026,7,10]]},"reference":[{"key":"2026072810105597700_cit1a","doi-asserted-by":"publisher","first-page":"1705","DOI":"10.1039\/D0OB02377A","article-title":"Recent Advances\nin the Rh-Catalyzed Cascade Arene C\u2013H Bond Activation\/Annulation\ntoward Diverse Heterocyclic Compounds","volume":"19","author":"Wang","year":"2021","journal-title":"Org.\nBiomol. 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