{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T21:04:14Z","timestamp":1789506254163,"version":"build-2803163510"},"reference-count":39,"publisher":"American Chemical Society (ACS)","issue":"36","license":[{"start":{"date-parts":[[2026,8,31]],"date-time":"2026-08-31T00:00:00Z","timestamp":1788134400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000015","name":"U.S. Department of Energy","doi-asserted-by":"publisher","award":["DE-AC05-76RL01830"],"award-info":[{"award-number":["DE-AC05-76RL01830"]}],"id":[{"id":"10.13039\/100000015","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,9,15]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>As global demand for light olefins continues to increase, driven by expanding plastics production and the need for jet fuel precursors, biomass-derived oxygenates such as methyl-ethyl-ketone (MEK) have emerged as promising intermediates for olefin production. This study investigates the selective hydrodeoxygenation of MEK to butene over copper catalysts supported on Al2O3, SiO2, and SiO2\u2013Al2O3, each offering distinct acid characteristics. Among the catalysts evaluated, 10Cu\/SiO2\u2013Al2O3 achieved the highest olefin selectivity (97.6%) while maintaining a high MEK conversion level (&amp;gt;80%) due to its acidity and favorable metal\u2013support interactions. Further studies revealed that at temperatures above 210 \u00b0C, the reaction pathway progressively shifts from hydrodeoxygenation toward aldol-condensation, producing undesired carboxylic acids and ketones, while simultaneously accelerating deactivation through hard-coke formation. A scaled-up experiment using a 100 g catalyst batch demonstrated that 10Cu\/SiO2\u2013Al2O3 operated at 210 \u00b0C (1 atm, w8 h space velocity = 0.8 h\u20131, PMEK = 12%) sustains high conversion (\u223c90%) and olefin selectivity (94\u201397%) for more than 140 h, with full recovery of activity and selectivity after mild oxidative regeneration. These results establish 10Cu\/SiO2\u2013Al2O3 as a robust and scalable catalyst for MEK hydrodeoxygenation, offering mechanistic insight into activity, selectivity, and deactivation pathways critical for industrial implementation.<\/jats:p>","DOI":"10.1021\/acsomega.6c07329","type":"journal-article","created":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T07:11:50Z","timestamp":1788419510000},"page":"54622-54631","source":"Crossref","is-referenced-by-count":0,"title":["Direct Conversion\nof Methyl\u2013Ethyl-Ketone into\nOlefins Precursors of Fuels and Chemicals over Supported Cu Catalysts"],"prefix":"10.1021","volume":"11","author":[{"given":"Hanzhong","family":"Shi","sequence":"first","affiliation":[{"name":"Pacific Northwest National Laboratory , 902 Battelle Boulevard , , ,","place":["Richland, Washington, United States, 99354"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3372-588X","authenticated-orcid":true,"given":"Yang","family":"He","sequence":"additional","affiliation":[{"name":"Pacific Northwest National Laboratory , 902 Battelle Boulevard , , ,","place":["Richland, Washington, United States, 99354"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4943-9455","authenticated-orcid":true,"given":"Vanessa Lebarbier","family":"Dagle","sequence":"additional","affiliation":[{"name":"Pacific Northwest National Laboratory , 902 Battelle Boulevard , , ,","place":["Richland, Washington, United States, 99354"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2026,8,31]]},"reference":[{"issue":"2","key":"2026091516093695700_cit1","doi-asserted-by":"publisher","first-page":"171","DOI":"10.1016\/J.ENG.2017.02.006","article-title":"New Trends in Olefin\nProduction","volume":"3","author":"Amghizar","year":"2017","journal-title":"Engineering"},{"issue":"4","key":"2026091516093695700_cit2","doi-asserted-by":"publisher","first-page":"425","DOI":"10.1016\/j.energy.2005.04.001","article-title":"Olefins from\nconventional and heavy\nfeedstocks: Energy use in steam cracking and alternative processes","volume":"31","author":"Ren","year":"2006","journal-title":"Energy"},{"issue":"3","key":"2026091516093695700_cit3","doi-asserted-by":"publisher","first-page":"1922","DOI":"10.1021\/acscatal.5b00007","article-title":"Methanol to\nOlefins (MTO): From Fundamentals\nto Commercialization","volume":"5","author":"Tian","year":"2015","journal-title":"ACS Catal."},{"issue":"38","key":"2026091516093695700_cit4","doi-asserted-by":"publisher","first-page":"7184","DOI":"10.1002\/anie.200604504","article-title":"Synergies between Bio-\nand Oil Refineries for the Production of Fuels\nfrom Biomass","volume":"46","author":"Huber","year":"2007","journal-title":"Angew. 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U.S. Patent 20,190,194,814 A1, 2019."},{"issue":"1","key":"2026091516093695700_cit21","doi-asserted-by":"publisher","first-page":"686","DOI":"10.15376\/biores.6.1.686-699","article-title":"Catalytic hydrogenation\nand oxidation of biomass-derived\nlevulinic acid","volume":"6","author":"Gong","year":"2011","journal-title":"BioRes."},{"key":"2026091516093695700_cit22","unstructured":"Dagle, V. M.; Dagle, R. A.\n          Process for\nconversion of levulinic acid to ketones. U.S. Patent 9,663,435 B1, 2016."},{"issue":"20","key":"2026091516093695700_cit23","doi-asserted-by":"publisher","first-page":"4822","DOI":"10.3390\/molecules29204822","article-title":"Enhanced Yield\nof Methyl Ethyl Ketone through Levulinic Acid Decarboxylation in the\nAgNO(3)\/K(2)S(2)O(8) System: Mechanistic Insights and Characterization\nof Metallic Species","volume":"29","author":"Guzma\u0301n Barrera","year":"2024","journal-title":"Molecules"},{"issue":"29","key":"2026091516093695700_cit24","doi-asserted-by":"publisher","first-page":"11096","DOI":"10.1021\/ja204235v","article-title":"Direct Conversion of Bio-ethanol\nto Isobutene on Nanosized\nZnxZryOz Mixed Oxides with Balanced Acid\u2013Base Sites","volume":"133","author":"Sun","year":"2011","journal-title":"J. Am. Chem. 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