{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T19:50:57Z","timestamp":1791921057721,"version":"4.3.4"},"reference-count":38,"publisher":"American Chemical Society (ACS)","issue":"40","license":[{"start":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T00:00:00Z","timestamp":1790640000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100016221","name":"Rowan University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100016221","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2026,10,13]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>A sustainable oxidation protocol for the synthesis of oxaziridines from aldimines is described using hydrotalcite as a recyclable heterogeneous catalyst and hydrogen peroxide as a green oxidant. This operationally simple method proceeds under mild heating and avoids the need for chlorinated oxidants or metal-based reagents traditionally employed for imine oxidation. Across 25 representative substrates, including both aromatic and aliphatic aldimines, the transformation delivers the corresponding oxaziridines in yields up to 90%. The hydrotalcite catalyst can be readily recovered by filtration and reused with minimal loss of activity. Together, these features establish a practical, scalable, and environmentally conscious approach to oxaziridine synthesis that expands the toolbox of green nitrogen-transfer chemistry. Method optimization, scope, and limitations are discussed.<\/jats:p>","DOI":"10.1021\/acsomega.6c07428","type":"journal-article","created":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T06:02:24Z","timestamp":1790661744000},"page":"61701-61707","source":"Crossref","is-referenced-by-count":0,"title":["MgAlO\n                    <i>t<\/i>\n                    Bu Catalyzed Synthesis\nof Oxaziridines"],"prefix":"10.1021","volume":"11","author":[{"given":"Autumn J.","family":"Vossler","sequence":"first","affiliation":[{"name":"Rowan University , , , ,","place":["Glassboro, New Jersey, United States, 08028"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chrishene R. B.","family":"Mapitigama","sequence":"additional","affiliation":[{"name":"Rowan University , , , ,","place":["Glassboro, New Jersey, United States, 08028"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Prinsee R.","family":"Patel","sequence":"additional","affiliation":[{"name":"Rowan University , , , ,","place":["Glassboro, New Jersey, United States, 08028"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicholas J.","family":"Lahr","sequence":"additional","affiliation":[{"name":"Rowan University , , , ,","place":["Glassboro, New Jersey, United States, 08028"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"DaEisha N.","family":"Robinson","sequence":"additional","affiliation":[{"name":"Rowan University , , , ,","place":["Glassboro, New Jersey, United States, 08028"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4329-6289","authenticated-orcid":true,"given":"Rashanique D.","family":"Quarels","sequence":"additional","affiliation":[{"name":"Rowan University , , , ,","place":["Glassboro, New Jersey, United States, 08028"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2026,9,29]]},"reference":[{"key":"2026101315091146800_cit1","doi-asserted-by":"publisher","first-page":"1756","DOI":"10.1002\/adsc.202001372","article-title":"Recent Advances\nin the Preparations and Synthetic Applications of Oxaziridines and\nDiaziridines","volume":"363","author":"Ravindra","year":"2021","journal-title":"Adv. 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Commun."},{"key":"2026101315091146800_cit31","doi-asserted-by":"publisher","first-page":"9357","DOI":"10.1016\/S0040-4020(00)00906-6","article-title":"Catalytic C\u2013C\nBond Formation Promoted by Mg\u2013Al\u2013O\u2013t-Bu\nHydrotalcite","volume":"56","author":"Choudary","year":"2000","journal-title":"Tetrahedron"},{"key":"2026101315091146800_cit32","doi-asserted-by":"publisher","first-page":"1493","DOI":"10.3390\/catal11121493","article-title":"Fine Crystalline Mg-Al Hydrotalcites\nas Catalysts for Baeyer-Villiger Oxidation of Cyclohexanone with H2O2","volume":"11","author":"Karcz","year":"2021","journal-title":"Catalysts"},{"key":"2026101315091146800_cit33","doi-asserted-by":"publisher","first-page":"1203","DOI":"10.1055\/s-1998-1919","article-title":"Superactive Mg-Al-O-t-Bu\nHydrotalcite for Epoxidation of Olefins","volume":"11","author":"Choudary","year":"1998","journal-title":"Synlett"},{"key":"2026101315091146800_cit34","doi-asserted-by":"publisher","first-page":"2051","DOI":"10.1002\/ejoc.200600980","article-title":"An Environmentally\nFriendly Oxidation System for the Selective Oxygenation of Aldimines\nto Oxaziridines with Anhydrous TBHP and Alumina-Supported MoO 3 as\na Recyclable Heterogeneous Catalyst","volume":"2007","author":"Singhal","year":"2007","journal-title":"Eur. J.\nOrg. Chem."},{"key":"2026101315091146800_cit35","doi-asserted-by":"publisher","first-page":"659","DOI":"10.1021\/jo01062a004","article-title":"Reactions\nof Hydrogen Peroxide. VII.\nAlkali-Catalyzed Epoxidation and Oxidation Using a Nitrile as Co-reactant","volume":"26","author":"Payne","year":"1961","journal-title":"J. Org. Chem."},{"key":"2026101315091146800_cit36","doi-asserted-by":"publisher","first-page":"3745","DOI":"10.1016\/S0957-4166(98)00407-8","article-title":"Surprising\nstereoselectivity in the Payne epoxidation of terpinen-4-ol with acetonitrile\/hydrogen\nperoxide","volume":"9","author":"Frank","year":"1998","journal-title":"Tetrahedron:Asymmetry"},{"key":"2026101315091146800_cit37","doi-asserted-by":"publisher","first-page":"1263","DOI":"10.1039\/C6GC03589B","article-title":"Atom economical synthesis\nof N-alkylbenzamides via\nthe iron(iii) sulfate catalyzed rearrangement of 2-alkyl-3-aryloxaziridines\nin water and in the presence of a surfactant","volume":"19","author":"Krai\u0308em","year":"2017","journal-title":"Green Chem."},{"key":"2026101315091146800_cit38","doi-asserted-by":"publisher","first-page":"9995","DOI":"10.1039\/D1CC03855A","article-title":"Weak base-promoted\nselective rearrangement of oxaziridines\nto amides via visible-light photoredox catalysis","volume":"57","author":"Park","year":"2021","journal-title":"Chem. Commun."}],"container-title":["ACS Omega"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsomega.6c07428","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/acsodf\/article-pdf\/11\/40\/61701\/68685218\/acsomega.6c07428.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/pubs.acs.org\/acsodf\/article-pdf\/11\/40\/61701\/68685218\/acsomega.6c07428.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T19:30:50Z","timestamp":1791919850000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/acsodf\/article\/11\/40\/61701\/5440437\/MgAlOtBu-Catalyzed-Synthesis-of-Oxaziridines"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9,29]]},"references-count":38,"journal-issue":{"issue":"40","published-online":{"date-parts":[[2026,9,29]]},"published-print":{"date-parts":[[2026,10,13]]}},"URL":"https:\/\/doi.org\/10.1021\/acsomega.6c07428","relation":{},"ISSN":["2470-1343"],"issn-type":[{"value":"2470-1343","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9,29]]}}}