{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T18:08:14Z","timestamp":1792174094128,"version":"4.4.0"},"reference-count":24,"publisher":"American Chemical Society (ACS)","issue":"4","license":[{"start":{"date-parts":[[2018,4,24]],"date-time":"2018-04-24T00:00:00Z","timestamp":1524528000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/pubs.acs.org\/page\/policy\/authorchoice_termsofuse.html"}],"funder":[{"DOI":"10.13039\/100000864","name":"Michael J. 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The results of this study indicate that compound 11 is a secondary lead compound for structure\u2013activity relationship studies aimed at identifying a suitable compound for positron emission tomography-imaging studies of insoluble Asyn aggregates in Parkinson\u2019s disease.<\/jats:p>","DOI":"10.1021\/acsomega.7b01897","type":"journal-article","created":{"date-parts":[[2018,4,24]],"date-time":"2018-04-24T13:41:26Z","timestamp":1524577286000},"page":"4486-4493","source":"Crossref","is-referenced-by-count":42,"title":["Chalcones and Five-Membered Heterocyclic Isosteres Bind to Alpha Synuclein Fibrils\nin Vitro"],"prefix":"10.1021","volume":"3","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2833-7727","authenticated-orcid":true,"given":"Chia-Ju","family":"Hsieh","sequence":"first","affiliation":[{"name":"University of Pennsylvania School of Medicine , , , ,","place":["Philadelphia, Pennsylvania, United States, 19104"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kuiying","family":"Xu","sequence":"additional","affiliation":[{"name":"University of Pennsylvania School of Medicine , , , ,","place":["Philadelphia, Pennsylvania, United States, 19104"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Iljung","family":"Lee","sequence":"additional","affiliation":[{"name":"University of Pennsylvania School of Medicine , , , ,","place":["Philadelphia, Pennsylvania, United States, 19104"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas J. 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