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Reaction efficiency with copper(II) sulfate and sodium iodide in an aqueous slurry under mild conditions is a manifold higher than in organic solvents. Water-soluble hosts of the cyclodextrin family solubilize the compounds in aqueous media and affect the reaction efficiency through conformation control and steric interactions. Computational chemistry and spectral titration provide information on the host\u2013guest complex structure and insight into the mechanistic basis of the observed effects.<\/jats:p>","DOI":"10.1021\/acsomega.9b02466","type":"journal-article","created":{"date-parts":[[2019,10,17]],"date-time":"2019-10-17T11:59:30Z","timestamp":1571313570000},"page":"17830-17836","source":"Crossref","is-referenced-by-count":4,"title":["Iodocyclization in Aqueous Media and Supramolecular\nReaction Control Using Water-Soluble Hosts"],"prefix":"10.1021","volume":"4","author":[{"given":"Treyvon","family":"Bokoskie","sequence":"first","affiliation":[{"name":"University of Nebraska Kearney , , , ,","place":["Kearney, Nebraska, United States, 68849"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher","family":"Cunningham","sequence":"additional","affiliation":[{"name":"University of West Florida , , , ,","place":["Pensacola, Florida, United States, 32514"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cory","family":"Kornman","sequence":"additional","affiliation":[{"name":"University of West Florida , , , ,","place":["Pensacola, Florida, United States, 32514"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8193-0004","authenticated-orcid":true,"given":"Tanay","family":"Kesharwani","sequence":"additional","affiliation":[{"name":"University of West Florida , , , ,","place":["Pensacola, Florida, United States, 32514"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6763-6711","authenticated-orcid":true,"given":"Mahesh","family":"Pattabiraman","sequence":"additional","affiliation":[{"name":"University of Nebraska Kearney , , , ,","place":["Kearney, Nebraska, United States, 68849"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2019,10,17]]},"reference":[{"key":"2026090207245467900_cit1","doi-asserted-by":"publisher","first-page":"281","DOI":"10.1016\/j.pharep.2016.11.007","article-title":"A review on antioxidant\npotential of bioactive heterocycle benzofuran: Natural and synthetic\nderivatives","volume":"69","author":"Chand","year":"2017","journal-title":"Pharmacol. 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