{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,23]],"date-time":"2026-07-23T16:48:53Z","timestamp":1784825333216,"version":"3.55.0"},"reference-count":40,"publisher":"American Chemical Society (ACS)","issue":"9","license":[{"start":{"date-parts":[[2024,8,13]],"date-time":"2024-08-13T00:00:00Z","timestamp":1723507200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,8,13]],"date-time":"2024-08-13T00:00:00Z","timestamp":1723507200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,8,13]],"date-time":"2024-08-13T00:00:00Z","timestamp":1723507200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/501100001411","name":"Indian Council of Medical Research","doi-asserted-by":"publisher","award":["5\/4\/7-5\/Nephro\/2022-NCD-II"],"award-info":[{"award-number":["5\/4\/7-5\/Nephro\/2022-NCD-II"]}],"id":[{"id":"10.13039\/501100001411","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ACS Pharmacol. Transl. Sci."],"published-print":{"date-parts":[[2024,9,13]]},"DOI":"10.1021\/acsptsci.4c00066","type":"journal-article","created":{"date-parts":[[2024,8,13]],"date-time":"2024-08-13T12:07:31Z","timestamp":1723550851000},"page":"2662-2676","source":"Crossref","is-referenced-by-count":3,"title":["Effect of an Autotaxin Inhibitor, 2-(4-Chlorophenyl)-7-methyl-8-pentylimidazo[1,2-<i>a<\/i>] Pyrimidin-5(8<i>H<\/i>)-one (CBT-295), on Bile Duct Ligation-Induced Chronic Liver Disease and Associated Hepatic Encephalopathy in Rats"],"prefix":"10.1021","volume":"7","author":[{"given":"Subhasis","family":"Roy","sequence":"first","affiliation":[{"name":"TCG Lifesciences Private Ltd., Sector V, Salt Lake, Kolkata 700091, West Bengal, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Monali","family":"Chakrabarti","sequence":"additional","affiliation":[{"name":"TCG Lifesciences Private Ltd., Sector V, Salt Lake, Kolkata 700091, West Bengal, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Trisha","family":"Mondal","sequence":"additional","affiliation":[{"name":"TCG Lifesciences Private Ltd., Sector V, Salt Lake, Kolkata 700091, West Bengal, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tapas Kumar","family":"Das","sequence":"additional","affiliation":[{"name":"TCG Lifesciences Private Ltd., Sector V, Salt Lake, Kolkata 700091, West Bengal, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tonmoy","family":"Sarkar","sequence":"additional","affiliation":[{"name":"TCG Lifesciences Private Ltd., Sector V, Salt Lake, Kolkata 700091, West Bengal, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sebak","family":"Datta","sequence":"additional","affiliation":[{"name":"TCG Lifesciences Private Ltd., Sector V, Salt Lake, Kolkata 700091, West Bengal, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0907-6699","authenticated-orcid":true,"given":"Mrinalkanti","family":"Kundu","sequence":"additional","affiliation":[{"name":"TCG Lifesciences Private Ltd., Sector V, Salt Lake, Kolkata 700091, West Bengal, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manish","family":"Banerjee","sequence":"additional","affiliation":[{"name":"TCG Lifesciences Private Ltd., Sector V, Salt Lake, Kolkata 700091, West Bengal, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8877-0573","authenticated-orcid":true,"given":"Onkar Prakash","family":"Kulkarni","sequence":"additional","affiliation":[{"name":"Metabolic Disorders and Neuroscience Research Laboratory, Department of Pharmacy, Birla Institute of Technology and Science, Pilani-Hyderabad Campus, Hyderabad 500078, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2024,8,13]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2018.09.014"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0243607"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-pathol-011110-130246"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1172\/JCI200524282"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1007\/s12072-017-9812-3"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.14218\/JCTH.2016.00069"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.3390\/jcm11071798"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1038\/s41392-020-00367-5"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1194\/jlr.R046391"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2010.08.008"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0143083"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0103532"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1038\/jid.2013.140"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1002\/hep.24273"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1016\/S0035-9203(97)90093-6"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.3892\/etm.2020.8680"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0038778"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1016\/S0076-6879(07)33001-2"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1016\/j.physbeh.2017.03.040"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1002\/hep.28973"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.14701\/kjhbps.2011.15.2.67"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1111\/liv.14911"},{"key":"ref23\/cit23","doi-asserted-by":"crossref","unstructured":"Sousa, T.; Castro, R. E.; Coutinho, A.; Rodrigues, C. M. P.; Prieto, M.; Fernandes, F. Experimental Cholestasis Research; Humana: New York, 2019; Vol. 1981, pp. 99\u2013115.","DOI":"10.1007\/978-1-4939-9420-5_7"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1159\/000374096"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1194\/jlr.R046458"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1097\/01.mcg.0000225642.90898.0e"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1124\/jpet.116.237156"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.15252\/emmm.202216333"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1038\/s41419-023-06022-5"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1155\/2017\/9173090"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.2131\/jts.37.1165"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0036322"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbi.2018.03.002"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1111\/j.1478-3231.2005.01012.x"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1155\/2012\/642108"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2010.03.040"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-4159.2009.05981.x"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.4103\/2347-8659.160845"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.1016\/j.jceh.2014.07.006"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.1021\/acschemneuro.2c00046"}],"container-title":["ACS Pharmacology &amp; Translational Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsptsci.4c00066","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsptsci.4c00066","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,9,13]],"date-time":"2024-09-13T13:55:03Z","timestamp":1726235703000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acsptsci.4c00066"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,8,13]]},"references-count":40,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2024,9,13]]}},"alternative-id":["10.1021\/acsptsci.4c00066"],"URL":"https:\/\/doi.org\/10.1021\/acsptsci.4c00066","relation":{},"ISSN":["2575-9108","2575-9108"],"issn-type":[{"value":"2575-9108","type":"print"},{"value":"2575-9108","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,8,13]]}}}