{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,16]],"date-time":"2026-10-16T22:24:59Z","timestamp":1792189499421,"version":"4.4.0"},"reference-count":60,"publisher":"American Chemical Society (ACS)","issue":"12","license":[{"start":{"date-parts":[[2024,11,9]],"date-time":"2024-11-09T00:00:00Z","timestamp":1731110400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,11,9]],"date-time":"2024-11-09T00:00:00Z","timestamp":1731110400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,11,9]],"date-time":"2024-11-09T00:00:00Z","timestamp":1731110400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/100000065","name":"National Institute of Neurological Disorders and Stroke","doi-asserted-by":"publisher","award":["R01NS100947"],"award-info":[{"award-number":["R01NS100947"]}],"id":[{"id":"10.13039\/100000065","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000065","name":"National Institute of Neurological Disorders and Stroke","doi-asserted-by":"publisher","award":["R21NS136070"],"award-info":[{"award-number":["R21NS136070"]}],"id":[{"id":"10.13039\/100000065","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000065","name":"National Institute of Neurological Disorders and Stroke","doi-asserted-by":"publisher","award":["R61NS130199"],"award-info":[{"award-number":["R61NS130199"]}],"id":[{"id":"10.13039\/100000065","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ACS Pharmacol. Transl. Sci."],"published-print":{"date-parts":[[2024,12,13]]},"DOI":"10.1021\/acsptsci.4c00516","type":"journal-article","created":{"date-parts":[[2024,11,9]],"date-time":"2024-11-09T09:33:58Z","timestamp":1731144838000},"page":"4056-4068","source":"Crossref","is-referenced-by-count":9,"title":["Suppressing the Inflammatory Prostaglandin Signaling after Thrombotic Stroke Ameliorates Ischemic Brain Injury and Facilitates Poststroke Recovery"],"prefix":"10.1021","volume":"7","author":[{"given":"Zhen","family":"Jin","sequence":"first","affiliation":[{"name":"Department of Pharmaceutical Sciences, College of Pharmacy, University of Tennessee Health Science Center, Memphis, Tennessee 38163, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chenyao","family":"Jiang","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Sciences, College of Pharmacy, University of Tennessee Health Science Center, Memphis, Tennessee 38163, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eun Bee","family":"Cho","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Sciences, College of Pharmacy, University of Tennessee Health Science Center, Memphis, Tennessee 38163, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sina","family":"Bahraminejad","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Sciences, College of Pharmacy, University of Tennessee Health Science Center, Memphis, Tennessee 38163, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juqian","family":"Han","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Sciences, College of Pharmacy, University of Tennessee Health Science Center, Memphis, Tennessee 38163, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2393-997X","authenticated-orcid":true,"given":"Jiukuan","family":"Hao","sequence":"additional","affiliation":[{"name":"Department of Pharmacological and Pharmaceutical Sciences, College of Pharmacy, University of Houston, Houston, Texas 77204, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiawang","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Sciences, College of Pharmacy, University of Tennessee Health Science Center, Memphis, Tennessee 38163, United States"},{"name":"Medicinal Chemistry Core, Office of Research, University of Tennessee Health Science Center, Memphis, Tennessee 38163, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying","family":"Yu","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Sciences, College of Pharmacy, University of Tennessee Health Science Center, Memphis, Tennessee 38163, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3955-8928","authenticated-orcid":true,"given":"Jianxiong","family":"Jiang","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Sciences, College of Pharmacy, University of Tennessee Health Science Center, Memphis, Tennessee 38163, United States"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2024,11,9]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbadis.2016.01.015"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1080\/10641960600549173"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awm106"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcomdis.2008.04.001"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCRESAHA.122.319951"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.l6983"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.5853\/jos.2016.01515"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2021.661955"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1016\/j.jneuroim.2006.11.014"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1007\/s00281-022-00943-7"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCRESAHA.121.319994"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1038\/s41582-021-00605-6"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.0000153797.33611.d8"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1002\/med.21744"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1007\/s13311-022-01191-1"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1177\/15353702231179926"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1016\/j.phrs.2020.105238"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1016\/j.prostaglandins.2009.04.003"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1016\/j.tips.2013.05.003"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1818544116"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.4485-03.2004"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1186\/2040-7378-2-12"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1016\/j.pharmthera.2020.107504"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2022.113966"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jmedchem.3c00655"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0909310107"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1111\/j.1476-5381.2011.01495.x"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1120195109"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1021\/ml400112h"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jmedchem.5b00567"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1021\/acschemneuro.7b00486"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jmedchem.1c00816"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1016\/j.bmcl.2023.129255"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1021\/acsptsci.0c00040"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jmedchem.9b01218"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1016\/j.brainres.2010.09.081"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.17.3.472"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.3791\/52434"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.1007\/s12035-020-01923-4"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-022-11793-6"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.1152\/ajpcell.00136.2018"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.2174\/1570159X18666200528143301"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.3389\/fnagi.2022.887032"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.1016\/j.hest.2020.09.001"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.1161\/STR.0000000000000430"},{"key":"ref46\/cit46","doi-asserted-by":"publisher","DOI":"10.1177\/0271678X211005877"},{"key":"ref47\/cit47","doi-asserted-by":"publisher","DOI":"10.3791\/55718"},{"key":"ref48\/cit48","doi-asserted-by":"publisher","DOI":"10.7150\/ijms.8140"},{"key":"ref49\/cit49","doi-asserted-by":"publisher","DOI":"10.1002\/ana.20461"},{"key":"ref50\/cit50","doi-asserted-by":"publisher","DOI":"10.1172\/JCI6579"},{"key":"ref51\/cit51","doi-asserted-by":"publisher","DOI":"10.1038\/5583"},{"key":"ref52\/cit52","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.96.18.10501"},{"key":"ref53\/cit53","doi-asserted-by":"publisher","DOI":"10.1016\/j.expneurol.2009.01.016"},{"key":"ref54\/cit54","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-4159.2008.05766.x"},{"key":"ref55\/cit55","doi-asserted-by":"publisher","DOI":"10.3791\/50370"},{"key":"ref56\/cit56","doi-asserted-by":"publisher","DOI":"10.1016\/j.nbd.2019.02.010"},{"key":"ref57\/cit57","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbih.2020.100132"},{"key":"ref58\/cit58","doi-asserted-by":"publisher","DOI":"10.1172\/JCI77487"},{"key":"ref59\/cit59","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-020-03160-0"},{"key":"ref60\/cit60","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuropharm.2022.109356"}],"container-title":["ACS Pharmacology & Translational Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsptsci.4c00516","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsptsci.4c00516","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,12,13]],"date-time":"2024-12-13T04:11:44Z","timestamp":1734063104000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acsptsci.4c00516"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,11,9]]},"references-count":60,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2024,12,13]]}},"alternative-id":["10.1021\/acsptsci.4c00516"],"URL":"https:\/\/doi.org\/10.1021\/acsptsci.4c00516","relation":{},"ISSN":["2575-9108","2575-9108"],"issn-type":[{"value":"2575-9108","type":"print"},{"value":"2575-9108","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,11,9]]}}}