{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T12:03:57Z","timestamp":1792065837611,"version":"4.4.0"},"reference-count":209,"publisher":"American Chemical Society (ACS)","issue":"10","license":[{"start":{"date-parts":[[2025,9,15]],"date-time":"2025-09-15T00:00:00Z","timestamp":1757894400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ACS Pharmacol. Transl. Sci."],"published-print":{"date-parts":[[2025,10,10]]},"DOI":"10.1021\/acsptsci.5c00289","type":"journal-article","created":{"date-parts":[[2025,9,15]],"date-time":"2025-09-15T10:28:39Z","timestamp":1757932119000},"page":"3432-3452","source":"Crossref","is-referenced-by-count":6,"title":["<i>Para<\/i>-Cresol and the Brain: Emerging Role in Neurodevelopmental and Neurodegenerative Disorders and Therapeutic Perspectives"],"prefix":"10.1021","volume":"8","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-9576-2551","authenticated-orcid":true,"given":"Laura","family":"Bertarini","sequence":"first","affiliation":[{"name":"Department of Life Sciences, University of Modena and Reggio Emilia, Via Giuseppe Campi 103-287, 41125 Modena, Italy"},{"name":"Clinical and Experimental Medicine PhD Program, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Via Giuseppe Campi 287, 41125 Modena, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Federico","family":"Imbeni","sequence":"additional","affiliation":[{"name":"Department of Life Sciences, University of Modena and Reggio Emilia, Via Giuseppe Campi 103-287, 41125 Modena, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Virginia","family":"Brighenti","sequence":"additional","affiliation":[{"name":"Department of Life Sciences, University of Modena and Reggio Emilia, Via Giuseppe Campi 103-287, 41125 Modena, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-0673-7494","authenticated-orcid":true,"given":"Isabella","family":"Martusciello","sequence":"additional","affiliation":[{"name":"Department of Life Sciences, University of Modena and Reggio Emilia, Via Giuseppe Campi 103-287, 41125 Modena, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9822-6862","authenticated-orcid":true,"given":"Federica","family":"Pellati","sequence":"additional","affiliation":[{"name":"Department of Life Sciences, University of Modena and Reggio Emilia, Via Giuseppe Campi 103-287, 41125 Modena, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2332-3166","authenticated-orcid":true,"given":"Silvia","family":"Alboni","sequence":"additional","affiliation":[{"name":"Department of Life Sciences, University of Modena and Reggio Emilia, Via Giuseppe Campi 103-287, 41125 Modena, Italy"},{"name":"Center for Neuroscience and Neurotechnology","place":["Modena, Italy"]},{"name":"University of Modena and Reggio Emilia","place":["Modena, Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2025,9,15]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gfi170"},{"key":"ref2\/cit2","unstructured":"U.S. Department of Health and\nHuman Services Toxicological\nProfile for Cresols, 2008. https:\/\/www.atsdr.cdc.gov\/toxprofiles\/tp34.pdf."},{"key":"ref3\/cit3","volume-title":"Cresols: Health and Safety Guide","author":"World Health Organization, International Programme on Chemical Safety, United Nations Environment Programme &amp; International Labour Organization","year":"1996"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.3389\/fnins.2021.738220"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.3390\/ijms241914621"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0812874106"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1002\/mnfr.201100542"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1093\/femsec\/fiy125"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1053\/j.jrn.2014.09.002"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gfq624"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.3177\/jnsv.51.182"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2036.1998.00377.x"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/32.10.2094"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1538\/expanim.56.301"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/29.12.1448"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1093\/jn\/98.2.217"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodres.2020.109049"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1007\/BF00425340"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1016\/j.freeradbiomed.2004.11.020"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1007191"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2180-11-86"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.3390\/toxins9020052"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/14.12.2846"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1093\/toxsci\/kfaa072"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M008799200"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1124\/dmd.32.4.413"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1016\/S0090-9556(24)15358-5"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1007\/s00216-012-6277-z"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1016\/j.taap.2021.115553"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1093\/toxsci\/kfj061"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.3390\/pharmaceutics16060743"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhazmat.2021.128093"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1373\/clinchem.2005.050781"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1021\/jp9059517"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1002\/bdd.1834"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1124\/dmd.112.045617"},{"key":"ref37\/cit37","doi-asserted-by":"publisher","DOI":"10.1016\/j.biochi.2018.04.019"},{"key":"ref38\/cit38","doi-asserted-by":"publisher","DOI":"10.1373\/49.3.470"},{"key":"ref39\/cit39","doi-asserted-by":"publisher","DOI":"10.2152\/jmi.66.81"},{"key":"ref40\/cit40","doi-asserted-by":"publisher","DOI":"10.2215\/CJN.00160116"},{"key":"ref41\/cit41","doi-asserted-by":"publisher","DOI":"10.3390\/pharmaceutics13060857"},{"key":"ref42\/cit42","doi-asserted-by":"publisher","DOI":"10.3390\/toxins10120520"},{"key":"ref43\/cit43","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0067168"},{"key":"ref44\/cit44","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gfr672"},{"key":"ref45\/cit45","doi-asserted-by":"publisher","DOI":"10.1007\/s00216-012-5929-3"},{"key":"ref46\/cit46","doi-asserted-by":"publisher","DOI":"10.1097\/IMNA-D-24-00002"},{"key":"ref47\/cit47","doi-asserted-by":"publisher","DOI":"10.1002\/jcla.20456"},{"key":"ref48\/cit48","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gfr056"},{"key":"ref49\/cit49","doi-asserted-by":"publisher","DOI":"10.1016\/j.ab.2008.09.034"},{"key":"ref50\/cit50","doi-asserted-by":"publisher","DOI":"10.1177\/096032718800700307"},{"key":"ref51\/cit51","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gfq785"},{"key":"ref52\/cit52","doi-asserted-by":"publisher","DOI":"10.1016\/j.ntt.2012.09.002"},{"key":"ref53\/cit53","doi-asserted-by":"publisher","DOI":"10.3389\/fmmed.2022.959189"},{"key":"ref54\/cit54","doi-asserted-by":"publisher","DOI":"10.1128\/mSphere.00314-20"},{"key":"ref55\/cit55","doi-asserted-by":"publisher","DOI":"10.3390\/ijms26041513"},{"key":"ref56\/cit56","doi-asserted-by":"publisher","DOI":"10.1016\/j.cca.2019.10.038"},{"key":"ref57\/cit57","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbi.2022.11.004"},{"key":"ref58\/cit58","doi-asserted-by":"publisher","DOI":"10.3389\/fnins.2023.1268419"},{"key":"ref59\/cit59","doi-asserted-by":"publisher","DOI":"10.1038\/ki.2012.448"},{"key":"ref60\/cit60","doi-asserted-by":"publisher","DOI":"10.1186\/s40168-021-01103-z"},{"key":"ref61\/cit61","doi-asserted-by":"publisher","DOI":"10.1007\/s00726-021-03064-x"},{"key":"ref62\/cit62","doi-asserted-by":"publisher","DOI":"10.3390\/ijms21186687"},{"issue":"2","key":"ref63\/cit63","first-page":"18","volume":"22","author":"Shaw W.","year":"2023","journal-title":"Integr. Med."},{"key":"ref64\/cit64","doi-asserted-by":"publisher","DOI":"10.1080\/19490976.2024.2431651"},{"key":"ref65\/cit65","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-024-69124-w"},{"key":"ref66\/cit66","doi-asserted-by":"publisher","DOI":"10.1160\/th03-07-0491"},{"key":"ref67\/cit67","doi-asserted-by":"publisher","DOI":"10.3389\/fncel.2021.661838"},{"key":"ref68\/cit68","doi-asserted-by":"publisher","DOI":"10.1111\/bcpt.70065"},{"key":"ref69\/cit69","doi-asserted-by":"publisher","DOI":"10.1016\/j.bcp.2022.114984"},{"key":"ref70\/cit70","doi-asserted-by":"publisher","DOI":"10.1016\/j.biochi.2021.06.020"},{"key":"ref71\/cit71","doi-asserted-by":"publisher","DOI":"10.1016\/j.redox.2024.103433"},{"key":"ref72\/cit72","doi-asserted-by":"publisher","DOI":"10.3390\/antiox9080743"},{"key":"ref73\/cit73","doi-asserted-by":"publisher","DOI":"10.3390\/ijms19123824"},{"key":"ref74\/cit74","doi-asserted-by":"publisher","DOI":"10.1124\/dmd.105.006387"},{"key":"ref75\/cit75","doi-asserted-by":"publisher","DOI":"10.1021\/bi00426a005"},{"key":"ref76\/cit76","doi-asserted-by":"publisher","DOI":"10.1016\/0167-4838(90)90176-G"},{"key":"ref77\/cit77","doi-asserted-by":"publisher","DOI":"10.1155\/2016\/9730467"},{"key":"ref78\/cit78","doi-asserted-by":"publisher","DOI":"10.1155\/2012\/920953"},{"key":"ref79\/cit79","doi-asserted-by":"publisher","DOI":"10.1016\/j.mam.2008.08.006"},{"key":"ref80\/cit80","doi-asserted-by":"publisher","DOI":"10.3390\/antiox12020517"},{"key":"ref81\/cit81","doi-asserted-by":"publisher","DOI":"10.1016\/j.toxlet.2021.04.019"},{"key":"ref82\/cit82","doi-asserted-by":"publisher","DOI":"10.3969\/j.issn.1673-5374.2013.21.009"},{"key":"ref83\/cit83","doi-asserted-by":"publisher","DOI":"10.1042\/BJ20121778"},{"key":"ref84\/cit84","doi-asserted-by":"publisher","DOI":"10.18632\/oncotarget.20773"},{"key":"ref85\/cit85","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbadis.2012.09.006"},{"key":"ref86\/cit86","doi-asserted-by":"publisher","DOI":"10.3390\/ijms19102898"},{"key":"ref87\/cit87","doi-asserted-by":"publisher","DOI":"10.1111\/jcmm.15303"},{"key":"ref88\/cit88","doi-asserted-by":"publisher","DOI":"10.3934\/Neuroscience.2020003"},{"key":"ref89\/cit89","doi-asserted-by":"publisher","DOI":"10.1038\/35085068"},{"key":"ref90\/cit90","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.13442"},{"key":"ref91\/cit91","doi-asserted-by":"publisher","DOI":"10.3390\/biomedicines9091252"},{"key":"ref92\/cit92","doi-asserted-by":"publisher","DOI":"10.1111\/jnc.15604"},{"key":"ref93\/cit93","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awab320"},{"key":"ref94\/cit94","doi-asserted-by":"publisher","DOI":"10.1128\/spectrum.00073-22"},{"key":"ref95\/cit95","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbadis.2020.165859"},{"key":"ref96\/cit96","doi-asserted-by":"publisher","DOI":"10.3390\/brainsci10040233"},{"key":"ref97\/cit97","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbr.2014.07.037"},{"key":"ref98\/cit98","doi-asserted-by":"publisher","DOI":"10.1016\/j.arr.2021.101556"},{"key":"ref99\/cit99","doi-asserted-by":"publisher","DOI":"10.3390\/pharmaceutics15082081"},{"key":"ref100\/cit100","doi-asserted-by":"publisher","DOI":"10.3390\/biomedicines10051143"},{"key":"ref101\/cit101","doi-asserted-by":"publisher","DOI":"10.3934\/Neuroscience.2022002"},{"key":"ref102\/cit102","doi-asserted-by":"publisher","DOI":"10.1016\/j.yrtph.2004.09.005"},{"key":"ref103\/cit103","doi-asserted-by":"publisher","DOI":"10.3390\/cells11233782"},{"key":"ref104\/cit104","doi-asserted-by":"publisher","DOI":"10.1016\/j.toxlet.2016.01.009"},{"key":"ref105\/cit105","doi-asserted-by":"publisher","DOI":"10.1016\/j.taap.2013.10.016"},{"key":"ref106\/cit106","doi-asserted-by":"publisher","DOI":"10.3390\/ijms231911013"},{"key":"ref107\/cit107","doi-asserted-by":"publisher","DOI":"10.1016\/j.carres.2020.108225"},{"key":"ref108\/cit108","doi-asserted-by":"publisher","DOI":"10.1016\/j.tiv.2019.01.003"},{"key":"ref109\/cit109","doi-asserted-by":"publisher","DOI":"10.1080\/21688370.2022.2073175"},{"key":"ref110\/cit110","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gfab004"},{"key":"ref111\/cit111","doi-asserted-by":"publisher","DOI":"10.3109\/1354750X.2010.548010"},{"key":"ref112\/cit112","doi-asserted-by":"publisher","DOI":"10.1016\/j.brainres.2024.149427"},{"key":"ref113\/cit113","doi-asserted-by":"publisher","DOI":"10.3109\/1354750X.2014.936911"},{"key":"ref114\/cit114","doi-asserted-by":"publisher","DOI":"10.3390\/ijms24087078"},{"key":"ref115\/cit115","doi-asserted-by":"publisher","DOI":"10.3390\/metabo10110476"},{"key":"ref116\/cit116","doi-asserted-by":"publisher","DOI":"10.1002\/aur.2639"},{"key":"ref117\/cit117","doi-asserted-by":"publisher","DOI":"10.1007\/s12031-020-01482-2"},{"key":"ref118\/cit118","doi-asserted-by":"publisher","DOI":"10.3389\/fcimb.2020.00098"},{"key":"ref119\/cit119","doi-asserted-by":"publisher","DOI":"10.3389\/fncel.2017.00120"},{"issue":"1","key":"ref120\/cit120","first-page":"50","volume":"16","author":"Shaw W.","year":"2017","journal-title":"Integr. Med."},{"key":"ref121\/cit121","doi-asserted-by":"publisher","DOI":"10.1016\/j.anaerobe.2017.12.007"},{"key":"ref122\/cit122","doi-asserted-by":"publisher","DOI":"10.3389\/fnmol.2025.1576388"},{"key":"ref123\/cit123","doi-asserted-by":"publisher","DOI":"10.1002\/aur.1571"},{"key":"ref124\/cit124","doi-asserted-by":"publisher","DOI":"10.1007\/s11062-019-09764-1"},{"key":"ref125\/cit125","doi-asserted-by":"publisher","DOI":"10.1007\/s11062-019-09774-z"},{"key":"ref126\/cit126","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(14)61393-3"},{"key":"ref127\/cit127","doi-asserted-by":"publisher","DOI":"10.1186\/s13024-018-0304-2"},{"key":"ref128\/cit128","doi-asserted-by":"publisher","DOI":"10.3390\/metabo7020022"},{"key":"ref129\/cit129","doi-asserted-by":"publisher","DOI":"10.1016\/j.nbd.2021.105557"},{"key":"ref130\/cit130","doi-asserted-by":"publisher","DOI":"10.1007\/s00702-002-0808-2"},{"key":"ref131\/cit131","doi-asserted-by":"publisher","DOI":"10.1016\/j.brainres.2018.01.010"},{"key":"ref132\/cit132","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0b013e3181c34af5"},{"key":"ref133\/cit133","doi-asserted-by":"publisher","DOI":"10.1002\/mds.27581"},{"key":"ref134\/cit134","doi-asserted-by":"publisher","DOI":"10.3233\/JPD-191711"},{"key":"ref135\/cit135","doi-asserted-by":"publisher","DOI":"10.1002\/mds.26942"},{"key":"ref136\/cit136","doi-asserted-by":"publisher","DOI":"10.1186\/s13073-017-0428-y"},{"key":"ref137\/cit137","doi-asserted-by":"publisher","DOI":"10.1002\/mds.26307"},{"key":"ref138\/cit138","doi-asserted-by":"publisher","DOI":"10.1002\/mds.26069"},{"key":"ref139\/cit139","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(15)00007-1"},{"key":"ref140\/cit140","doi-asserted-by":"publisher","DOI":"10.3390\/nu13030732"},{"key":"ref141\/cit141","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.47861"},{"key":"ref142\/cit142","doi-asserted-by":"publisher","DOI":"10.3390\/microbiolres15020033"},{"key":"ref143\/cit143","doi-asserted-by":"publisher","DOI":"10.1038\/s41531-021-00156-z"},{"key":"ref144\/cit144","doi-asserted-by":"publisher","DOI":"10.1186\/s40478-015-0196-0"},{"key":"ref145\/cit145","doi-asserted-by":"publisher","DOI":"10.3233\/JPD-230357"},{"key":"ref146\/cit146","doi-asserted-by":"publisher","DOI":"10.1016\/j.toxlet.2021.12.003"},{"key":"ref147\/cit147","doi-asserted-by":"publisher","DOI":"10.1615\/CritRevEukaryotGeneExpr.2021037550"},{"key":"ref148\/cit148","doi-asserted-by":"publisher","DOI":"10.52586\/4952"},{"key":"ref149\/cit149","doi-asserted-by":"publisher","DOI":"10.1002\/mds.28052"},{"key":"ref150\/cit150","doi-asserted-by":"publisher","DOI":"10.1038\/s41531-023-00612-y"},{"key":"ref151\/cit151","doi-asserted-by":"publisher","DOI":"10.1186\/s13024-023-00694-5"},{"key":"ref152\/cit152","doi-asserted-by":"publisher","DOI":"10.1111\/ggi.12811"},{"key":"ref153\/cit153","doi-asserted-by":"publisher","DOI":"10.1038\/s41531-023-00612-y"},{"key":"ref154\/cit154","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0208752"},{"key":"ref155\/cit155","doi-asserted-by":"publisher","DOI":"10.1038\/jcbfm.2015.32"},{"key":"ref156\/cit156","doi-asserted-by":"publisher","DOI":"10.1186\/s40035-024-00430-z"},{"key":"ref157\/cit157","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-017-04949-2"},{"key":"ref158\/cit158","doi-asserted-by":"publisher","DOI":"10.1007\/s00228-009-0714-8"},{"key":"ref159\/cit159","doi-asserted-by":"publisher","DOI":"10.1046\/j.1471-4159.2002.01108.x"},{"key":"ref160\/cit160","doi-asserted-by":"publisher","DOI":"10.1007\/s10157-011-0460-y"},{"key":"ref161\/cit161","doi-asserted-by":"publisher","DOI":"10.3389\/fnagi.2019.00331"},{"key":"ref162\/cit162","doi-asserted-by":"publisher","DOI":"10.1016\/j.cbi.2022.110143"},{"key":"ref163\/cit163","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2023.1161850"},{"key":"ref164\/cit164","doi-asserted-by":"publisher","DOI":"10.1007\/s10753-022-01721-1"},{"key":"ref165\/cit165","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2019.09.001"},{"key":"ref166\/cit166","doi-asserted-by":"publisher","DOI":"10.1038\/s12276-024-01282-3"},{"key":"ref167\/cit167","doi-asserted-by":"publisher","DOI":"10.1038\/s12276-023-01146-2"},{"key":"ref168\/cit168","doi-asserted-by":"publisher","DOI":"10.1186\/s13024-023-00595-7"},{"key":"ref169\/cit169","doi-asserted-by":"publisher","DOI":"10.1038\/srep30028"},{"key":"ref170\/cit170","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-017-13601-y"},{"key":"ref171\/cit171","doi-asserted-by":"publisher","DOI":"10.1016\/j.neurobiolaging.2016.08.019"},{"key":"ref172\/cit172","doi-asserted-by":"publisher","DOI":"10.1186\/s40478-020-00988-5"},{"key":"ref173\/cit173","doi-asserted-by":"publisher","DOI":"10.1038\/srep41802"},{"key":"ref174\/cit174","doi-asserted-by":"publisher","DOI":"10.1038\/s41422-019-0216-x"},{"key":"ref175\/cit175","doi-asserted-by":"publisher","DOI":"10.3390\/biomedicines11061606"},{"key":"ref176\/cit176","doi-asserted-by":"publisher","DOI":"10.1007\/s11011-020-00561-y"},{"key":"ref177\/cit177","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.2016080816"},{"key":"ref178\/cit178","doi-asserted-by":"publisher","DOI":"10.3390\/toxins13020142"},{"key":"ref179\/cit179","doi-asserted-by":"publisher","DOI":"10.3390\/brainsci14111043"},{"key":"ref180\/cit180","doi-asserted-by":"publisher","DOI":"10.3390\/toxins10090367"},{"key":"ref181\/cit181","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.2019070728"},{"key":"ref182\/cit182","doi-asserted-by":"publisher","DOI":"10.1007\/s00418-018-1662-0"},{"key":"ref183\/cit183","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0193342"},{"key":"ref184\/cit184","doi-asserted-by":"publisher","DOI":"10.1016\/j.toxlet.2016.10.006"},{"key":"ref185\/cit185","doi-asserted-by":"publisher","DOI":"10.1093\/braincomms\/fcaf005"},{"key":"ref186\/cit186","doi-asserted-by":"publisher","DOI":"10.1186\/s40035-022-00279-0"},{"key":"ref187\/cit187","doi-asserted-by":"publisher","DOI":"10.3233\/JAD-215448"},{"key":"ref188\/cit188","doi-asserted-by":"publisher","DOI":"10.21203\/rs.3.rs-3941791\/v1"},{"key":"ref189\/cit189","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-020-65196-6"},{"key":"ref190\/cit190","doi-asserted-by":"publisher","DOI":"10.1002\/da.22279"},{"key":"ref191\/cit191","doi-asserted-by":"publisher","DOI":"10.1016\/j.euroneuro.2021.11.009"},{"key":"ref192\/cit192","doi-asserted-by":"publisher","DOI":"10.1038\/nrdp.2015.57"},{"key":"ref193\/cit193","doi-asserted-by":"publisher","DOI":"10.1007\/s13311-017-0597-9"},{"key":"ref194\/cit194","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbi.2023.09.005"},{"key":"ref195\/cit195","doi-asserted-by":"publisher","DOI":"10.1038\/s41398-024-02765-7"},{"key":"ref196\/cit196","doi-asserted-by":"publisher","DOI":"10.1038\/s41398-023-02643-8"},{"key":"ref197\/cit197","doi-asserted-by":"publisher","DOI":"10.1016\/j.ynstr.2022.100461"},{"key":"ref198\/cit198","doi-asserted-by":"publisher","DOI":"10.1097\/TA.0000000000003209"},{"key":"ref199\/cit199","volume-title":"The Oxford Handbook of the Microbiome-Gut-Brain Axis","author":"Loupy K. M.","year":"2020"},{"key":"ref200\/cit200","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2024.1349883"},{"key":"ref201\/cit201","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.96937"},{"key":"ref202\/cit202","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuro.2016.01.006"},{"key":"ref203\/cit203","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-019-57004-7"},{"key":"ref204\/cit204","doi-asserted-by":"publisher","DOI":"10.3389\/fnana.2025.1504065"},{"key":"ref205\/cit205","doi-asserted-by":"publisher","DOI":"10.1016\/j.clnu.2023.06.019"},{"key":"ref206\/cit206","doi-asserted-by":"publisher","DOI":"10.1007\/s10157-013-0902-9"},{"key":"ref207\/cit207","doi-asserted-by":"publisher","DOI":"10.1152\/physrev.00025.2013"},{"key":"ref208\/cit208","doi-asserted-by":"publisher","DOI":"10.3390\/pharmaceutics15102473"},{"key":"ref209\/cit209","doi-asserted-by":"publisher","DOI":"10.1007\/s11095-022-03193-2"}],"container-title":["ACS Pharmacology &amp; Translational Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsptsci.5c00289","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acsptsci.5c00289","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,10]],"date-time":"2025-10-10T08:12:44Z","timestamp":1760083964000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acsptsci.5c00289"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,9,15]]},"references-count":209,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2025,10,10]]}},"alternative-id":["10.1021\/acsptsci.5c00289"],"URL":"https:\/\/doi.org\/10.1021\/acsptsci.5c00289","relation":{},"ISSN":["2575-9108","2575-9108"],"issn-type":[{"value":"2575-9108","type":"print"},{"value":"2575-9108","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,9,15]]}}}