{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T17:55:41Z","timestamp":1789667741784,"version":"4.0.1"},"reference-count":36,"publisher":"American Chemical Society (ACS)","issue":"4","license":[{"start":{"date-parts":[[2024,4,8]],"date-time":"2024-04-08T00:00:00Z","timestamp":1712534400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,4,8]],"date-time":"2024-04-08T00:00:00Z","timestamp":1712534400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,4,8]],"date-time":"2024-04-08T00:00:00Z","timestamp":1712534400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"funder":[{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2021YFC2104100"],"award-info":[{"award-number":["2021YFC2104100"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["NSFC-22178018"],"award-info":[{"award-number":["NSFC-22178018"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ACS Synth. Biol."],"published-print":{"date-parts":[[2024,4,19]]},"DOI":"10.1021\/acssynbio.4c00123","type":"journal-article","created":{"date-parts":[[2024,4,8]],"date-time":"2024-04-08T13:54:05Z","timestamp":1712584445000},"page":"1100-1104","source":"Crossref","is-referenced-by-count":7,"title":["A Proline-Based Artificial Enzyme That Favors Aldol Condensation Enables Facile Synthesis of Aliphatic Ketones via Tandem Catalysis"],"prefix":"10.1021","volume":"13","author":[{"given":"Ning","family":"Nie","sequence":"first","affiliation":[{"name":"State Key Laboratory of Chemical Resource Engineering, Beijing University of Chemical Technology, Beijing 100029, China"},{"name":"Beijing Advanced Innovation Center for Soft Matter Science and Engineering, Beijing University of Chemical Technology, Beijing 100029, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ziye","family":"Zhao","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Chemical Resource Engineering, Beijing University of Chemical Technology, Beijing 100029, China"},{"name":"Beijing Advanced Innovation Center for Soft Matter Science and Engineering, Beijing University of Chemical Technology, Beijing 100029, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinwei","family":"Li","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Chemical Resource Engineering, Beijing University of Chemical Technology, Beijing 100029, China"},{"name":"Beijing Advanced Innovation Center for Soft Matter Science and Engineering, Beijing University of Chemical Technology, Beijing 100029, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yunting","family":"Liu","sequence":"additional","affiliation":[{"name":"School of Chemical Engineering and Technology, Hebei University of Technology, Tianjin 300130, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0014-611X","authenticated-orcid":true,"given":"Yifei","family":"Zhang","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Chemical Resource Engineering, Beijing University of Chemical Technology, Beijing 100029, China"},{"name":"Beijing Advanced Innovation Center for Soft Matter Science and Engineering, Beijing University of Chemical Technology, Beijing 100029, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2024,4,8]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"publisher","DOI":"10.1002\/cctc.201200709"},{"key":"ref2\/cit2","doi-asserted-by":"publisher","DOI":"10.1139\/cjc-2021-0053"},{"key":"ref3\/cit3","doi-asserted-by":"publisher","DOI":"10.1126\/science.1188934"},{"key":"ref4\/cit4","doi-asserted-by":"publisher","DOI":"10.1126\/science.aay8484"},{"key":"ref5\/cit5","doi-asserted-by":"publisher","DOI":"10.1038\/s41570-020-0191-2"},{"key":"ref6\/cit6","doi-asserted-by":"publisher","DOI":"10.1021\/acscatal.6b00758"},{"key":"ref7\/cit7","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0307979101"},{"key":"ref8\/cit8","doi-asserted-by":"publisher","DOI":"10.1021\/ja994280y"},{"key":"ref9\/cit9","doi-asserted-by":"publisher","DOI":"10.1039\/D0GC00726A"},{"key":"ref10\/cit10","doi-asserted-by":"publisher","DOI":"10.1016\/j.tet.2009.04.052"},{"key":"ref11\/cit11","doi-asserted-by":"publisher","DOI":"10.1021\/ol015799d"},{"key":"ref12\/cit12","doi-asserted-by":"publisher","DOI":"10.1002\/slct.202104261"},{"key":"ref13\/cit13","doi-asserted-by":"publisher","DOI":"10.1021\/cs100088m"},{"key":"ref14\/cit14","doi-asserted-by":"publisher","DOI":"10.1021\/jp7096845"},{"key":"ref15\/cit15","doi-asserted-by":"publisher","DOI":"10.1021\/jo200431v"},{"key":"ref16\/cit16","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201008042"},{"key":"ref17\/cit17","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201207123"},{"key":"ref18\/cit18","doi-asserted-by":"publisher","DOI":"10.1021\/acscatal.1c05579"},{"key":"ref19\/cit19","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-021-97585-w"},{"key":"ref20\/cit20","doi-asserted-by":"publisher","DOI":"10.1002\/chem.202103949"},{"key":"ref21\/cit21","doi-asserted-by":"publisher","DOI":"10.1002\/9781118828083.ch18"},{"key":"ref22\/cit22","doi-asserted-by":"publisher","DOI":"10.1007\/s00253-020-10845-z"},{"key":"ref23\/cit23","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-023-44452-z"},{"key":"ref24\/cit24","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-019-10928-0"},{"key":"ref25\/cit25","doi-asserted-by":"publisher","DOI":"10.1016\/j.cbpa.2017.12.001"},{"key":"ref26\/cit26","doi-asserted-by":"publisher","DOI":"10.1002\/chem.201002761"},{"key":"ref27\/cit27","doi-asserted-by":"publisher","DOI":"10.1002\/cctc.202101180"},{"key":"ref28\/cit28","doi-asserted-by":"publisher","DOI":"10.1016\/j.ica.2021.120288"},{"key":"ref29\/cit29","doi-asserted-by":"publisher","DOI":"10.1002\/ejoc.201901380"},{"key":"ref30\/cit30","doi-asserted-by":"publisher","DOI":"10.1002\/adsc.201300882"},{"key":"ref31\/cit31","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.1c05757"},{"key":"ref32\/cit32","doi-asserted-by":"publisher","DOI":"10.1002\/ejoc.201701322"},{"key":"ref33\/cit33","doi-asserted-by":"publisher","DOI":"10.1038\/nchem.1268"},{"key":"ref34\/cit34","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201806850"},{"key":"ref35\/cit35","doi-asserted-by":"publisher","DOI":"10.1021\/ja806584q"},{"key":"ref36\/cit36","doi-asserted-by":"publisher","DOI":"10.1016\/j.molcatb.2014.04.004"}],"container-title":["ACS Synthetic Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acssynbio.4c00123","content-type":"application\/pdf","content-version":"vor","intended-application":"unspecified"},{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/acssynbio.4c00123","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,4,19]],"date-time":"2024-04-19T08:15:49Z","timestamp":1713514549000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/acssynbio.4c00123"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,4,8]]},"references-count":36,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2024,4,19]]}},"alternative-id":["10.1021\/acssynbio.4c00123"],"URL":"https:\/\/doi.org\/10.1021\/acssynbio.4c00123","relation":{},"ISSN":["2161-5063","2161-5063"],"issn-type":[{"value":"2161-5063","type":"print"},{"value":"2161-5063","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,4,8]]}}}