{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,21]],"date-time":"2026-04-21T09:09:08Z","timestamp":1776762548602,"version":"3.51.2"},"reference-count":62,"publisher":"American Chemical Society (ACS)","issue":"20","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ACS Appl. Mater. Interfaces"],"published-print":{"date-parts":[[2013,10,23]]},"DOI":"10.1021\/am403554x","type":"journal-article","created":{"date-parts":[[2013,9,27]],"date-time":"2013-09-27T02:37:33Z","timestamp":1380249453000},"page":"10381-10388","source":"Crossref","is-referenced-by-count":72,"title":["Multilayer Dual-Polymer-Coated Upconversion Nanoparticles for Multimodal Imaging and Serum-Enhanced Gene Delivery"],"prefix":"10.1021","volume":"5","author":[{"given":"Lu","family":"He","sequence":"first","affiliation":[{"name":"Department\rof Radiology, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu 215006, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Liangzhu","family":"Feng","sequence":"additional","affiliation":[{"name":"Institute of Functional Nano & Soft Materials (FUNSOM) & Collaborative Innovation Center of Suzhou Nano Science and Technology, Soochow University, Suzhou, Jiangsu 215123, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Liang","family":"Cheng","sequence":"additional","affiliation":[{"name":"Institute of Functional Nano & Soft Materials (FUNSOM) & Collaborative Innovation Center of Suzhou Nano Science and Technology, Soochow University, Suzhou, Jiangsu 215123, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yumeng","family":"Liu","sequence":"additional","affiliation":[{"name":"Department\rof Radiology, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu 215006, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhiwei","family":"Li","sequence":"additional","affiliation":[{"name":"Institute of Functional Nano & Soft Materials (FUNSOM) & Collaborative Innovation Center of Suzhou Nano Science and Technology, Soochow University, Suzhou, Jiangsu 215123, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rui","family":"Peng","sequence":"additional","affiliation":[{"name":"Institute of Functional Nano & Soft Materials (FUNSOM) & Collaborative Innovation Center of Suzhou Nano Science and Technology, Soochow University, Suzhou, Jiangsu 215123, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yonggang","family":"Li","sequence":"additional","affiliation":[{"name":"Department\rof Radiology, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu 215006, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Liang","family":"Guo","sequence":"additional","affiliation":[{"name":"Department\rof Radiology, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu 215006, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhuang","family":"Liu","sequence":"additional","affiliation":[{"name":"Institute of Functional Nano & Soft Materials (FUNSOM) & Collaborative Innovation Center of Suzhou Nano Science and Technology, Soochow University, Suzhou, Jiangsu 215123, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"316","published-online":{"date-parts":[[2013,10,10]]},"reference":[{"key":"ref1\/cit1","doi-asserted-by":"crossref","first-page":"6054","DOI":"10.1002\/anie.200501907","volume":"44","author":"Wang L.","year":"2005","journal-title":"Angew. Chem., Int. Ed."},{"key":"ref2\/cit2","doi-asserted-by":"crossref","first-page":"6426","DOI":"10.1021\/ja060212h","volume":"128","author":"Mai H.-X.","year":"2006","journal-title":"J. Am. Chem. Soc."},{"key":"ref3\/cit3","doi-asserted-by":"crossref","first-page":"7838","DOI":"10.1021\/nn201896m","volume":"5","author":"Jin J.","year":"2011","journal-title":"ACS Nano"},{"key":"ref4\/cit4","doi-asserted-by":"crossref","first-page":"2781","DOI":"10.1002\/smll.201000418","volume":"6","author":"Chatterjee D. K.","year":"2010","journal-title":"Small"},{"key":"ref5\/cit5","doi-asserted-by":"crossref","first-page":"976","DOI":"10.1039\/b809132n","volume":"38","author":"Wang F.","year":"2009","journal-title":"Chem. Soc. Rev."},{"key":"ref6\/cit6","doi-asserted-by":"crossref","first-page":"10917","DOI":"10.1073\/pnas.0904792106","volume":"106","author":"Wu S.","year":"2009","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"ref7\/cit7","doi-asserted-by":"crossref","first-page":"7523","DOI":"10.1002\/ange.201101447","volume":"123","author":"Cheng L.","year":"2011","journal-title":"Angew. Chem., Int. Ed."},{"key":"ref8\/cit8","doi-asserted-by":"crossref","first-page":"4649","DOI":"10.1002\/chem.200802106","volume":"15","author":"Yang J.","year":"2009","journal-title":"Chem.\u2014Eur. J."},{"key":"ref9\/cit9","doi-asserted-by":"crossref","first-page":"4765","DOI":"10.1002\/adma.200801056","volume":"20","author":"Li Z.","year":"2008","journal-title":"Adv. Mater."},{"key":"ref10\/cit10","doi-asserted-by":"crossref","first-page":"1110","DOI":"10.1016\/j.biomaterials.2010.09.069","volume":"32","author":"Wang C.","year":"2011","journal-title":"Biomaterials"},{"key":"ref11\/cit11","doi-asserted-by":"crossref","first-page":"4054","DOI":"10.1021\/nn300436b","volume":"6","author":"Liu K.","year":"2012","journal-title":"ACS Nano"},{"key":"ref12\/cit12","doi-asserted-by":"crossref","first-page":"2937","DOI":"10.1002\/smll.201201765","volume":"9","author":"Yang Y.","year":"2013","journal-title":"Small"},{"key":"ref13\/cit13","doi-asserted-by":"crossref","first-page":"7530","DOI":"10.1016\/j.biomaterials.2012.06.028","volume":"33","author":"Xiao Q.","year":"2012","journal-title":"Biomaterials"},{"key":"ref14\/cit14","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1038\/nrc1894","volume":"6","author":"Castano A. P.","year":"2006","journal-title":"Nat. Rev. Cancer"},{"key":"ref15\/cit15","doi-asserted-by":"crossref","first-page":"1839","DOI":"10.1039\/c0an00144a","volume":"135","author":"Wang F.","year":"2010","journal-title":"Analyst"},{"key":"ref16\/cit16","doi-asserted-by":"crossref","first-page":"1323","DOI":"10.1039\/C1CS15187H","volume":"41","author":"Zhou J.","year":"2012","journal-title":"Chem. Soc. Rev."},{"key":"ref17\/cit17","doi-asserted-by":"crossref","first-page":"937","DOI":"10.1016\/j.biomaterials.2007.10.051","volume":"29","author":"Chatterjee D. K.","year":"2008","journal-title":"Biomaterials"},{"key":"ref18\/cit18","doi-asserted-by":"crossref","first-page":"3125","DOI":"10.1002\/anie.201107919","volume":"51","author":"Yang Y.","year":"2012","journal-title":"Angew. Chem., Int. Ed."},{"key":"ref19\/cit19","doi-asserted-by":"crossref","first-page":"3287","DOI":"10.1016\/j.biomaterials.2010.01.040","volume":"31","author":"Zhou J.","year":"2010","journal-title":"Biomaterials"},{"key":"ref20\/cit20","doi-asserted-by":"crossref","first-page":"1079","DOI":"10.1016\/j.biomaterials.2011.10.039","volume":"33","author":"Xing H.","year":"2012","journal-title":"Biomaterials"},{"key":"ref21\/cit21","doi-asserted-by":"crossref","first-page":"853","DOI":"10.1002\/adfm.200800765","volume":"19","author":"Kumar R.","year":"2009","journal-title":"Adv. Funct. Mater."},{"key":"ref22\/cit22","doi-asserted-by":"crossref","first-page":"3834","DOI":"10.1021\/nl802223f","volume":"8","author":"Nyk M.","year":"2008","journal-title":"Nano Lett."},{"key":"ref23\/cit23","first-page":"1079","volume":"33","author":"Xing H.","year":"2013","journal-title":"Sci. Rep."},{"key":"ref24\/cit24","doi-asserted-by":"crossref","first-page":"7078","DOI":"10.1016\/j.biomaterials.2010.05.065","volume":"31","author":"Xiong L.","year":"2010","journal-title":"Biomaterials"},{"key":"ref25\/cit25","doi-asserted-by":"crossref","first-page":"582","DOI":"10.1016\/j.cbpa.2010.08.014","volume":"14","author":"Mader H. S.","year":"2010","journal-title":"Curr. Opin. Chem. Biol."},{"key":"ref26\/cit26","doi-asserted-by":"crossref","first-page":"3077","DOI":"10.1002\/adfm.201202992","volume":"23","author":"Wang C.","year":"2013","journal-title":"Adv. Funct. Mater."},{"key":"ref27\/cit27","doi-asserted-by":"crossref","first-page":"4375","DOI":"10.1002\/anie.201300183","volume":"52","author":"Liu J.","year":"2013","journal-title":"Angew. Chem., Int. Ed."},{"key":"ref28\/cit28","doi-asserted-by":"crossref","first-page":"1580","DOI":"10.1038\/nm.2933","volume":"18","author":"Idris N. M.","year":"2012","journal-title":"Nat. Med."},{"key":"ref29\/cit29","doi-asserted-by":"crossref","first-page":"73","DOI":"10.2217\/17435889.3.1.73","volume":"3","author":"Chatterjee D. K.","year":"2008","journal-title":"Nanomedicine"},{"key":"ref30\/cit30","doi-asserted-by":"crossref","first-page":"2285","DOI":"10.1002\/smll.200900692","volume":"5","author":"Qian H. S.","year":"2009","journal-title":"Small"},{"key":"ref31\/cit31","doi-asserted-by":"crossref","first-page":"865","DOI":"10.1016\/S0141-0229(03)00205-9","volume":"33","author":"Prather K. J.","year":"2003","journal-title":"Enzyme Microb. Technol."},{"key":"ref32\/cit32","doi-asserted-by":"crossref","first-page":"380","DOI":"10.1016\/S0167-7799(00)01475-X","volume":"18","author":"Ferreira G. N.","year":"2000","journal-title":"Trends Biotechnol."},{"key":"ref33\/cit33","doi-asserted-by":"crossref","first-page":"2060","DOI":"10.1016\/j.biomaterials.2005.09.020","volume":"27","author":"Mansouri S.","year":"2006","journal-title":"Biomaterials"},{"key":"ref34\/cit34","doi-asserted-by":"crossref","first-page":"1565","DOI":"10.1016\/j.biomaterials.2006.11.018","volume":"28","author":"Tan W. B.","year":"2007","journal-title":"Biomaterials"},{"key":"ref35\/cit35","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1088\/0022-3727\/36\/13\/201","volume":"36","author":"Pankhurst Q. A.","year":"2003","journal-title":"J. Phys. D: Appl. Phys."},{"key":"ref36\/cit36","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1038\/sj.cgt.7700357","volume":"8","author":"Ito A.","year":"2001","journal-title":"Cancer Gene Ther."},{"key":"ref37\/cit37","doi-asserted-by":"crossref","first-page":"1391","DOI":"10.1021\/bc060367e","volume":"18","author":"Derfus A. M.","year":"2007","journal-title":"Bioconjug. Chem."},{"key":"ref38\/cit38","doi-asserted-by":"crossref","first-page":"9006","DOI":"10.1021\/ja800086u","volume":"130","author":"Yezhelyev M. V.","year":"2008","journal-title":"J. Am. Chem. Soc."},{"key":"ref39\/cit39","doi-asserted-by":"crossref","first-page":"1759","DOI":"10.1039\/b806051g","volume":"38","author":"Boisselier E.","year":"2009","journal-title":"Chem. Soc. Rev."},{"key":"ref40\/cit40","doi-asserted-by":"crossref","first-page":"3237","DOI":"10.1002\/ange.200600214","volume":"118","author":"Han G.","year":"2006","journal-title":"Angew. Chem., Int. Ed."},{"key":"ref41\/cit41","doi-asserted-by":"crossref","first-page":"8483","DOI":"10.1073\/pnas.1114551109","volume":"109","author":"Jayakumar M. K. G.","year":"2012","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"ref42\/cit42","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1039\/C2NR32835F","volume":"5","author":"Yang Y.","year":"2013","journal-title":"Nanoscale"},{"key":"ref43\/cit43","doi-asserted-by":"crossref","first-page":"1252","DOI":"10.1039\/c0nr00680g","volume":"3","author":"Feng L.","year":"2011","journal-title":"Nanoscale"},{"key":"ref44\/cit44","doi-asserted-by":"crossref","first-page":"3714","DOI":"10.1021\/cm201297x","volume":"23","author":"Johnson N. J.","year":"2011","journal-title":"Chem. Mater."},{"key":"ref45\/cit45","doi-asserted-by":"crossref","first-page":"21077","DOI":"10.1021\/jp107725r","volume":"114","author":"Ryu J.","year":"2010","journal-title":"J. Phys. Chem. C"},{"key":"ref46\/cit46","doi-asserted-by":"crossref","first-page":"4470","DOI":"10.1002\/adfm.201101040","volume":"21","author":"He M.","year":"2011","journal-title":"Adv. Funct. Mater."},{"key":"ref47\/cit47","doi-asserted-by":"crossref","first-page":"1061","DOI":"10.1038\/nature08777","volume":"463","author":"Wang F.","year":"2010","journal-title":"Nature"},{"key":"ref48\/cit48","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1021\/bc0601929","volume":"18","author":"Zhou M.","year":"2007","journal-title":"Bioconjug. Chem."},{"key":"ref49\/cit49","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1021\/bc049895l","volume":"16","author":"Zhu J.","year":"2005","journal-title":"Bioconjug. Chem."},{"key":"ref50\/cit50","doi-asserted-by":"crossref","first-page":"2899","DOI":"10.1016\/j.biomaterials.2007.02.027","volume":"28","author":"Tian H.","year":"2007","journal-title":"Biomaterials"},{"key":"ref51\/cit51","doi-asserted-by":"crossref","first-page":"1989","DOI":"10.1002\/smll.201202538","volume":"9","author":"Feng L.","year":"2013","journal-title":"Small"},{"key":"ref52\/cit52","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1016\/j.jconrel.2006.06.025","volume":"114","author":"Patnaik S.","year":"2006","journal-title":"J. Controlled Release"},{"key":"ref53\/cit53","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1016\/S0928-0987(03)00102-7","volume":"19","author":"Tiyaboonchai W.","year":"2003","journal-title":"Eur. J. Pharm. Sci."},{"key":"ref54\/cit54","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1093\/nar\/30.2.e9","volume":"30","author":"Durocher Y.","year":"2002","journal-title":"Nucleic Acids Res."},{"key":"ref55\/cit55","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1038\/sj.gt.3301089","volume":"7","author":"Kawakami S.","year":"2000","journal-title":"Gene Ther."},{"key":"ref56\/cit56","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/S0300-9629(96)00403-3","volume":"118","author":"Kakuta K.","year":"1997","journal-title":"Comp. Biochem. Physiol., Part A: Mol. Integr. Physiol."},{"key":"ref57\/cit57","doi-asserted-by":"crossref","first-page":"1117","DOI":"10.1096\/fj.06-7380com","volume":"21","author":"Huang R.-Q.","year":"2007","journal-title":"FASEB J."},{"key":"ref58\/cit58","doi-asserted-by":"crossref","first-page":"494","DOI":"10.1021\/bc049775d","volume":"16","author":"Yang P.-H.","year":"2005","journal-title":"Bioconjug. Chem."},{"key":"ref59\/cit59","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1089\/hum.1997.8.4-467","volume":"8","author":"Xu L.","year":"1997","journal-title":"Hum. Gene Ther."},{"key":"ref60\/cit60","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1089\/hum.1996.7.3-275","volume":"7","author":"Cheng P.-W.","year":"1996","journal-title":"Hum. Gene Ther."},{"key":"ref61\/cit61","doi-asserted-by":"crossref","first-page":"622","DOI":"10.1166\/jnn.2010.1738","volume":"10","author":"Yang A.","year":"2010","journal-title":"J. Nanosci. Nanotechnol."},{"key":"ref62\/cit62","doi-asserted-by":"crossref","first-page":"9511","DOI":"10.1016\/j.biomaterials.2010.09.049","volume":"31","author":"Lesniak A.","year":"2010","journal-title":"Biomaterials"}],"container-title":["ACS Applied Materials & Interfaces"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/pubs.acs.org\/doi\/pdf\/10.1021\/am403554x","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,22]],"date-time":"2023-04-22T04:35:00Z","timestamp":1682138100000},"score":1,"resource":{"primary":{"URL":"https:\/\/pubs.acs.org\/doi\/10.1021\/am403554x"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,10,10]]},"references-count":62,"journal-issue":{"issue":"20","published-print":{"date-parts":[[2013,10,23]]}},"alternative-id":["10.1021\/am403554x"],"URL":"https:\/\/doi.org\/10.1021\/am403554x","relation":{},"ISSN":["1944-8244","1944-8252"],"issn-type":[{"value":"1944-8244","type":"print"},{"value":"1944-8252","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,10,10]]}}}