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The method is rapid and sensitive: sub-nanomolar concentrations of the target anthrax lethal factor DNA could be detected in \u223c1 min. Further, our method is selective, which can differentiate the target DNA from other single-stranded DNA molecules at the single-base resolution. This sequence-specific detection approach should find useful application in the development of nanopore sensors for the detection of other pathogens.<\/jats:p>","DOI":"10.1021\/am500749p","type":"journal-article","created":{"date-parts":[[2014,5,7]],"date-time":"2014-05-07T13:48:50Z","timestamp":1399470530000},"page":"7334-7339","source":"Crossref","is-referenced-by-count":43,"title":["Nanopore Biosensor for Label-Free and Real-Time Detection\nof Anthrax Lethal Factor"],"prefix":"10.1021","volume":"6","author":[{"given":"Liang","family":"Wang","sequence":"first","affiliation":[{"name":"Illinois Institute of Technology , , 3101 South Dearborn Street , , ,","place":["Chicago, Illinois, United States, 60616"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yujing","family":"Han","sequence":"additional","affiliation":[{"name":"Illinois Institute of Technology , , 3101 South Dearborn Street , , ,","place":["Chicago, Illinois, United States, 60616"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuo","family":"Zhou","sequence":"additional","affiliation":[{"name":"Illinois Institute of Technology , , 3101 South Dearborn Street , , ,","place":["Chicago, Illinois, United States, 60616"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guihua","family":"Wang","sequence":"additional","affiliation":[{"name":"Illinois Institute of Technology , , 3101 South Dearborn Street , , ,","place":["Chicago, Illinois, United States, 60616"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiyun","family":"Guan","sequence":"additional","affiliation":[{"name":"Illinois Institute of Technology , , 3101 South Dearborn Street , , ,","place":["Chicago, Illinois, United States, 60616"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2014,5,7]]},"reference":[{"key":"2026090211383255200_cit1","volume-title":"The Global Burden of Disease:\n2004 Update","author":"World Health Organization.","year":"2008"},{"key":"2026090211383255200_cit2","doi-asserted-by":"crossref","first-page":"3249","DOI":"10.1039\/c2lc40630f","article-title":"Microfluidic\nDesigns and Techniques Using Lab-on-a-Chip Devices for Pathogen Detection\nfor Point-of-Care Diagnostics","volume":"12","author":"Foudeh","year":"2012","journal-title":"Lab Chip"},{"key":"2026090211383255200_cit3","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1007\/s10096-013-1813-0","article-title":"Recent\nAdvances in Molecular Medicine\nTechniques for the Diagnosis, Prevention, and Control of Infectious\nDiseases","volume":"32","author":"Franc\u0327a","year":"2013","journal-title":"Eur. 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