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Pharmaceutics"},{"key":"ref26\/cit26","doi-asserted-by":"crossref","first-page":"659","DOI":"10.1021\/mp900015y","volume":"6","author":"Davis M. E.","year":"2009","journal-title":"Mol. Pharmaceutics"},{"key":"ref27\/cit27","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/j.jconrel.2008.07.035","volume":"132","author":"Weber N.","year":"2008","journal-title":"J. Controlled Release"},{"key":"ref28\/cit28","doi-asserted-by":"crossref","first-page":"1396","DOI":"10.1021\/bc8000722","volume":"19","author":"Patil M. L.","year":"2008","journal-title":"Bioconjugate Chem."},{"key":"ref29\/cit29","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1016\/j.jconrel.2008.07.006","volume":"131","author":"Chono S.","year":"2008","journal-title":"J. Controlled Release"},{"key":"ref30\/cit30","doi-asserted-by":"crossref","first-page":"7638","DOI":"10.1158\/0008-5472.CAN-07-6614","volume":"68","author":"Tran M. 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