{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T16:58:22Z","timestamp":1791219502027,"version":"4.1.0"},"reference-count":59,"publisher":"American Chemical Society (ACS)","issue":"7","license":[{"start":{"date-parts":[[2008,6,6]],"date-time":"2008-06-06T00:00:00Z","timestamp":1212710400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2008,6,6]],"date-time":"2008-06-06T00:00:00Z","timestamp":1212710400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2008,6,6]],"date-time":"2008-06-06T00:00:00Z","timestamp":1212710400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-045"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2008,7,15]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:p>Although catalytic asymmetric synthesis has undergone tremendous growth in the last 30 years, chiral auxiliary-aided asymmetric synthesis continues to attract considerable attention. Chiral N-tert-butanesulfinamide, as pioneered by Ellman and co-workers, is undoubtedly one of the most efficient auxiliaries developed to date; it allows the preparation, through simple conversion, of a diverse range of enantiopure amines, which are ubiquitous in natural products and biologically active molecules. Following on from our studies of the SmI2-mediated asymmetric syntheses of \u03b1,\u03b3-substituted \u03b3-butyrolactones, we found that simple homocoupling of chiral N-tert-butanesulfinyl imines in the presence of SmI2 produced enantiopure vicinal C2-symmetric diamines in high yield. In addition, C2-unsymmetric chiral diamines are readily prepared through SmI2-mediated cross-couplings of N-tert-butanesulfinyl imines and nitrones; these transformations represented the first successful examples of asymmetric cross-coupling between two different imine species. Subsequently, we discovered another useful reaction induced by SmI2, the efficient cross-coupling of N-tert-butanesulfinyl imines and aldehydes, which provides ready access to enantiopure anti-1,2-amino alcohols. The synthetic applicability of this reaction was demonstrated through its use in the facile total syntheses of (3R,4S)-statine, d-erythro-sphinganine, (+)-CP-99,994, and (+)-L-733,060.<\/jats:p>\n                  <jats:p>The Zn\/In-mediated allylation of chiral N-tert-butanesulfinyl imines yields homoallylic amines. After pondering the reaction mechanism, we developed optimal reaction conditions for reversing the stereogenic outcome, thereby allowing the preparation of enantiopure homoallylic amines of either handedness from single enantiomers of the (R)- or (S)-sulfinyl imine. When a benzoyl-substituted allyl bromide is used for allylation, the reaction proceeds smoothly to give 2-vinyl-substituted anti-1,2-amino alcohols in high yields and diastereoselectivities, another simple method for preparing enantiopure amino alcohols. We employed these reactions in the syntheses of enantiopure allylglycine, 3-allyl-isoindolinones, and (\u2212)-cytoxazone. Further studies led to the discovery that the allylations of N-tert-butanesulfinyl aldimines can be performed in water.<\/jats:p>\n                  <jats:p>The reactions described in this Account are among the simplest and most efficient synthetic methods available for preparing enantio-enriched diamines, amino alcohols, homoallylic amines, and other amine derivatives. These reactions are additionally attractive because of the ready availability of the starting materials, the simplicity of the reaction conditions, and the high degree of stereochemical control. Their applications in the total syntheses of several biologically interesting molecules illustrate the versatility of these transformations; we hope that they will stimulate the development of new synthetic methods.<\/jats:p>","DOI":"10.1021\/ar7002623","type":"journal-article","created":{"date-parts":[[2008,6,6]],"date-time":"2008-06-06T02:02:49Z","timestamp":1212717769000},"page":"831-840","source":"Crossref","is-referenced-by-count":269,"title":["An Advance on Exploring\n                    <i>N<\/i>\n                    -\n                    <i>tert<\/i>\n                    -Butanesulfinyl Imines in Asymmetric Synthesis of Chiral Amines"],"prefix":"10.1021","volume":"41","author":[{"given":"Guo-Qiang","family":"Lin","sequence":"first","affiliation":[{"name":"Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 354 Feng Lin Road, Shanghai 200032, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ming-Hua","family":"Xu","sequence":"additional","affiliation":[{"name":"Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 354 Feng Lin Road, Shanghai 200032, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu-Wu","family":"Zhong","sequence":"additional","affiliation":[{"name":"Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 354 Feng Lin Road, Shanghai 200032, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xing-Wen","family":"Sun","sequence":"additional","affiliation":[{"name":"Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 354 Feng Lin Road, Shanghai 200032, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"316","published-online":{"date-parts":[[2008,6,6]]},"reference":[{"key":"2026081306015202800_cit1a","doi-asserted-by":"crossref","first-page":"1984","DOI":"10.1021\/ar020066u","article-title":"N-tert-Butanesulfinyl Imines: Versatile Intermediates for the Asymmetric Synthesis of Amines","volume":"35","author":"Ellman","year":"2002","journal-title":"Acc. Chem. Res."},{"key":"2026081306015202800_cit1b","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1351\/pac200375010039","article-title":"Application of tert-Butanesulfinamide in the Asymmetric Synthesis of Amines","volume":"75","author":"Ellman","year":"2003","journal-title":"Pure Appl. Chem."},{"key":"2026081306015202800_cit1c","first-page":"93","article-title":"Enantiopure Sulfoxides and Sulfinamides: Recent Developments in Their Stereoselective Synthesis and Application to Asymmetric Synthesis","volume":"38","author":"Senanayake","year":"2005","journal-title":"Aldrichim. Acta"},{"key":"2026081306015202800_cit1d","first-page":"8868","article-title":"Chiral Non-racemic Sulfinimines: Versatile Reagents for Asymmetric Synthesis","volume":"62","author":"Daniel","year":"2006","journal-title":"Tetrahedron"},{"key":"2026081306015202800_cit2a","doi-asserted-by":"crossref","first-page":"1278","DOI":"10.1021\/jo982059i","article-title":"Synthesis of Enantiomerically Pure N-tert-Butanesulfinyl Imines (tert-Butanesulfinimines) by the Direct Condensation of tert-Butanesulfinamide with Aldehydes and Ketones","volume":"64","author":"Liu","year":"1999","journal-title":"J. Org. Chem."},{"key":"2026081306015202800_cit2b","first-page":"1334","article-title":"KHSO4-Mediated Condensation Reaction of tert-Butanesulfinamide with Aldehydes. Preparation of tert-Butanesulfinyl Aldimines","author":"Huang","year":"2005","journal-title":"Synlett"},{"key":"2026081306015202800_cit3a","doi-asserted-by":"crossref","first-page":"11276","DOI":"10.1021\/ja0363462","article-title":"Development and Application of a New General Method for the Asymmetric Synthesis of syn- and anti-1,3-Amino Alcohols","volume":"125","author":"Kochi","year":"2003","journal-title":"J. Am. Chem. Soc."},{"key":"2026081306015202800_cit3b","doi-asserted-by":"crossref","first-page":"15652","DOI":"10.1021\/ja044753n","article-title":"Asymmetric \u03b1-Alkylation of N\u2032-tert-Butanesulfinyl Amidines. Application to the Total Synthesis of (6R,7S)-7-Amino-7,8-dihydro-\u03b1-bisabolene","volume":"126","author":"Kochi","year":"2004","journal-title":"J. Am. Chem. Soc."},{"key":"2026081306015202800_cit4a","doi-asserted-by":"crossref","first-page":"1092","DOI":"10.1021\/ja044003d","article-title":"Diastereoselective and Enantioselective Rh(I)-Catalyzed Additions of Arylboronic Acids to N-tert-Butanesulfinyl and N-Diphenylphosphinoyl Aldimines","volume":"127","author":"Weix","year":"2005","journal-title":"J. Am. Chem. Soc."},{"key":"2026081306015202800_cit4b","doi-asserted-by":"crossref","first-page":"6303","DOI":"10.1021\/ja060529h","article-title":"Asymmetric Synthesis of Protected Arylglycines by Rhodium-Catalyzed Addition of Arylboronic Acids to N-tert-Butanesulfinyl Imino Esters","volume":"128","author":"Beenen","year":"2006","journal-title":"J. Am. Chem. 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Lett."},{"key":"2026081306015202800_cit6c","doi-asserted-by":"crossref","first-page":"3953","DOI":"10.1021\/jo0155153","article-title":"Development of a New Reaction System for the Synthesis of Highly Optically Active \u03b1,\u03b3-Substituted \u03b3-Butyrolactones","volume":"66","author":"Xu","year":"2001","journal-title":"J. Org. Chem."},{"key":"2026081306015202800_cit7","doi-asserted-by":"crossref","first-page":"10351","DOI":"10.1016\/j.tet.2003.09.101","article-title":"Twenty-five Years of Organic Chemistry with Diiodosamarium: An Overview","volume":"59","author":"Kagan","year":"2003","journal-title":"Tetrahedron"},{"key":"2026081306015202800_cit8a","doi-asserted-by":"crossref","first-page":"3167","DOI":"10.1021\/cr0406561","article-title":"\u03b1,\u03b2-Diamino Acids: Biological Significance and Synthetic Approaches","volume":"105","author":"Viso","year":"2005","journal-title":"Chem. Rev."},{"key":"2026081306015202800_cit8b","doi-asserted-by":"crossref","first-page":"2580","DOI":"10.1002\/(SICI)1521-3773(19981016)37:19<2580::AID-ANIE2580>3.0.CO;2-L","article-title":"The Chemistry of Vicinal Diamines","volume":"37","author":"Lucet","year":"1998","journal-title":"Angew. Chem., Int. Ed."},{"key":"2026081306015202800_cit8c","doi-asserted-by":"crossref","first-page":"2561","DOI":"10.1016\/S0040-4020(00)00149-6","article-title":"The Synthesis of Vicinal Amino Alcohols","volume":"56","author":"Bergmeier","year":"2000","journal-title":"Tetrahedron"},{"key":"2026081306015202800_cit8d","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1021\/ja028782e","article-title":"A Direct Catalytic Asymmetric Mannich-type Reaction to syn-Amino Alcohols","volume":"125","author":"Trost","year":"2003","journal-title":"J. Am. Chem. Soc."},{"key":"2026081306015202800_cit8e","doi-asserted-by":"crossref","first-page":"827","DOI":"10.1021\/ja0174231","article-title":"The Proline-Catalyzed Direct Asymmetric Three-Component Mannich Recation: Scope, Optimization, and Application to the Highly Enantioselective Synthesis of 1,2-Amino Alcohols","volume":"124","author":"List","year":"2002","journal-title":"J. Am. Chem. Soc."},{"key":"2026081306015202800_cit8f","doi-asserted-by":"crossref","first-page":"8777","DOI":"10.1021\/ja0482435","article-title":"Direct Catalytic Asymmetric Mannich-type Reaction of Hydroxyketone Using a Et2Zn\/Linked-BINOL Complex: Synthesis of Either anti- or syn-\u03b2-Amino Alcohols","volume":"126","author":"Matsunaga","year":"2004","journal-title":"J. Am. Chem. Soc."},{"key":"2026081306015202800_cit9","doi-asserted-by":"crossref","first-page":"11688","DOI":"10.1021\/ja074698t","article-title":"Catalytic Asymmetric Diamination of Conjugated Dienes and Trienes","volume":"129","author":"Du","year":"2007","journal-title":"J. Am. Chem. Soc."},{"key":"2026081306015202800_cit10a","doi-asserted-by":"crossref","first-page":"9421","DOI":"10.1021\/jo981396o","article-title":"Cp2VCl2-Catalyzed Meso-Selective Pinacol Coupling Reaction of Aldimines in the Presence of Chlorosilane and Zinc Metal","volume":"63","author":"Hatano","year":"1998","journal-title":"J. Org. Chem."},{"key":"2026081306015202800_cit10b","doi-asserted-by":"crossref","first-page":"873","DOI":"10.1055\/s-1998-1790","article-title":"Practical and Efficient Synthesis of C2 Symmetrical Diamines with Zn\/Me3SiCl","author":"Alexakis","year":"1998","journal-title":"Synlett"},{"key":"2026081306015202800_cit10c","doi-asserted-by":"crossref","first-page":"6475","DOI":"10.1016\/j.tet.2004.06.029","article-title":"Zn-Mediated Catalytic Photoreduction of Aldimines. One-Pot Synthesis and Separation of meso and d,lC2 Symmetrical Diamines","volume":"60","author":"Ortega","year":"2004","journal-title":"Tetrahedron"},{"key":"2026081306015202800_cit11","doi-asserted-by":"crossref","first-page":"1635","DOI":"10.1055\/s-2003-41419","article-title":"Highly Chemoselective Crossed Imino Pinacol Coupling Reaction Using the Synergetic Effect of Boron Trifluoride Etherate and Trichloromethylsilane","author":"Shimizu","year":"2003","journal-title":"Synlett"},{"key":"2026081306015202800_cit12","doi-asserted-by":"crossref","first-page":"4747","DOI":"10.1021\/ol0479803","article-title":"Highly Diastereoselective and Enantioselective Synthesis of Enantiopure C2-Symmetrical Vicinal Diamines by Reductive Homocoupling of Chiral N-tert-Butanesulfinyl Imines","volume":"6","author":"Zhong","year":"2004","journal-title":"Org. Lett."},{"key":"2026081306015202800_cit13","doi-asserted-by":"crossref","first-page":"3953","DOI":"10.1021\/ol048444d","article-title":"Samarium Diiodide-Induced Asymmetric Synthesis of Optically Pure Unsymmetrical Vicinal Diamines by Reductive Cross-Coupling of Nitrones with N-tert-Butanesulfinyl Imines","volume":"6","author":"Zhong","year":"2004","journal-title":"Org. Lett."},{"key":"2026081306015202800_cit14","doi-asserted-by":"crossref","first-page":"11956","DOI":"10.1021\/ja054401w","article-title":"A Highly Efficient and Direct Approach for Synthesis of Enantiopure \u03b2-Amino Alcohols by Reductive Cross-Coupling of Chiral N-tert-Butanesulfinyl Imines with Aldehydes","volume":"127","author":"Zhong","year":"2005","journal-title":"J. Am. Chem. Soc."},{"key":"2026081306015202800_cit15a","doi-asserted-by":"crossref","first-page":"8301","DOI":"10.1021\/ja000479v","article-title":"Asymmetric Synthesis of \u03b2-Amino Alcohols by Cross-Pinacol Coupling of Planar Chiral Ferrocenecarboxaldehyde with Imines","volume":"122","author":"Taniguchi","year":"2000","journal-title":"J. Am. Chem. Soc."},{"key":"2026081306015202800_cit15b","doi-asserted-by":"crossref","first-page":"835","DOI":"10.1021\/ol0255256","article-title":"Asymmetric Synthesis of \u03b2-Amino Alcohols by Reductive Cross-Coupling of Benzylideneamine with Planar Chiral Benzaldehydes","volume":"4","author":"Tanaka","year":"2002","journal-title":"Org. Lett."},{"key":"2026081306015202800_cit15c","doi-asserted-by":"crossref","first-page":"2330","DOI":"10.1039\/b405406g","article-title":"First Asymmetric SmI2-Induced Cross-Coupling of Cr(CO)3 Aromatic Nitrone Complexes with Carbonyl Compounds","author":"Chavarot","year":"2004","journal-title":"Chem. Commun."},{"key":"2026081306015202800_cit16a","doi-asserted-by":"crossref","first-page":"5637","DOI":"10.1021\/jo010383z","article-title":"Synthesis of (+)- and (\u2212)-Satine via Chiral Sulfoxide Chemistry","volume":"66","author":"Pesenti","year":"2001","journal-title":"J. Org. Chem."},{"key":"2026081306015202800_cit16b","doi-asserted-by":"crossref","first-page":"8521","DOI":"10.1016\/S0040-4020(01)00804-3","article-title":"Diastereoselective Synthesis of Enantiopure \u03b2-Amino-\u03b2-hydroxy Acids by Reformatsky Reaction of Chiral \u03b1-Dibenzylamino Aldehydes","volume":"57","author":"Andre\u0301s","year":"2001","journal-title":"Tetrahedron"},{"key":"2026081306015202800_cit16c","doi-asserted-by":"crossref","first-page":"3233","DOI":"10.1021\/jo030355b","article-title":"Straightforward Synthesis of Sphinganines via a Serine-Derived Weinreb Amide","volume":"69","author":"So","year":"2004","journal-title":"J. Org. Chem."},{"key":"2026081306015202800_cit16d","doi-asserted-by":"crossref","first-page":"7675","DOI":"10.1021\/jo034755a","article-title":"Efficient Synthesis of Enantiomerically Pure 2-Acylaziridines: Facile Synthesis of N-Boc-safingol, N-Boc-d-erythro-sphinganine, and N-Boc-spisulosine from a Common Intermediate","volume":"68","author":"Yun","year":"2003","journal-title":"J. Org. Chem."},{"key":"2026081306015202800_cit17a","doi-asserted-by":"crossref","first-page":"4911","DOI":"10.1021\/jm00104a018","article-title":"Discovery of a Potent Substance P Antagonist: Recognition of the Key Molecular Determinant","volume":"35","author":"Desai","year":"1992","journal-title":"J. Med. Chem."},{"key":"2026081306015202800_cit17b","doi-asserted-by":"crossref","first-page":"2545","DOI":"10.1016\/S0960-894X(01)80280-8","article-title":"Piperidine-Ether Based hNK1 Antagonists 1: Determination of the Relative and Absolute Stereochemical Requirements","volume":"4","author":"Harrison","year":"1994","journal-title":"Bioorg. Med. Chem. Lett."},{"key":"2026081306015202800_cit18a","doi-asserted-by":"crossref","first-page":"8927","DOI":"10.1016\/j.tetlet.2005.10.054","article-title":"A Concise and Practical Catalytic Asymmetric Synthesis of (\u2212)-CP-99,994 and (\u2212)-L-733,061","volume":"46","author":"Takahashi","year":"2005","journal-title":"Tetrahedron Lett."},{"key":"2026081306015202800_cit18b","doi-asserted-by":"crossref","first-page":"982","DOI":"10.1016\/j.tetasy.2007.04.006","article-title":"Enantioselective Synthesis of (+)-L-733,060","volume":"18","author":"Cherian","year":"2007","journal-title":"Tetrahedron: Asymmetry"},{"key":"2026081306015202800_cit19","doi-asserted-by":"crossref","first-page":"3307","DOI":"10.1021\/jo8002979","article-title":"Concise Asymmetric Synthesis of (+)-CP-99,994 and (+)-L-733,060 via Efficient Construction of Homochiral syn-1,2-Diamines and syn-1,2-Amino Alcohols","volume":"73","author":"Liu","year":"2008","journal-title":"J. Org. Chem."},{"key":"2026081306015202800_cit20","doi-asserted-by":"crossref","first-page":"8883","DOI":"10.1016\/S0040-4020(99)00451-2","article-title":"Asymmetric Synthesis of Chiral Amines by Highly Diastereoselective 1,2-Additions of Organometallic Reagents to N-tert-Butanesulfinyl Imines","volume":"55","author":"Cogan","year":"1999","journal-title":"Tetrahedron"},{"key":"2026081306015202800_cit21a","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1016\/S0957-4166(02)00099-X","article-title":"Asymmetric Synthesis of Diarylmethylamines by Diastereoselective Addition of Organometallic Reagents to Chiral N-tert-Butanesulfinimines: Switchover of Diastereofacial Selectivity","volume":"13","author":"Plobeck","year":"2002","journal-title":"Tetrahedron: Asymmetry"},{"key":"2026081306015202800_cit21b","doi-asserted-by":"crossref","first-page":"6859","DOI":"10.1021\/jo0609834","article-title":"Reversal of Diastereofacial Selectivity in Hydride Reductions of N-tert-Butanesulfinyl Imines","volume":"71","author":"Colyer","year":"2006","journal-title":"J. Org. Chem."},{"key":"2026081306015202800_cit21c","doi-asserted-by":"crossref","first-page":"626","DOI":"10.1021\/jo0616512","article-title":"One-Pot Asymmetric Synthesis of Either Diastereomer of tert-Butanesulfinyl-Protected Amines from Ketones","volume":"72","author":"Tanuwidjaja","year":"2007","journal-title":"J. Org. Chem."},{"key":"2026081306015202800_cit22","doi-asserted-by":"crossref","first-page":"3823","DOI":"10.1016\/j.tetasy.2004.10.031","article-title":"Indium-Mediated Diastereoselective Addition of Allyl Bromides to Enantiomerically Pure N-tert-Butanesulfinyl Aldimines","volume":"15","author":"Foubelo","year":"2004","journal-title":"Tetrahedron: Asymmetry"},{"key":"2026081306015202800_cit23","doi-asserted-by":"crossref","first-page":"4979","DOI":"10.1021\/ol062216x","article-title":"Room-Temperature Highly Diastereoselective Zn-Mediated Allylation of Chiral N-tert-Butanesulfinyl Imines: Remarkable Reaction Condition Controlled Stereoselectivity Reversal","volume":"8","author":"Sun","year":"2006","journal-title":"Org. Lett."},{"key":"2026081306015202800_cit24a","doi-asserted-by":"crossref","first-page":"7687","DOI":"10.1021\/ja061510h","article-title":"Catalytic Enantioselective Allylation of Ketoimines","volume":"128","author":"Wada","year":"2006","journal-title":"J. Am. Chem. Soc."},{"key":"2026081306015202800_cit24b","doi-asserted-by":"crossref","first-page":"5686","DOI":"10.1021\/ja0486418","article-title":"Enantioselective Allylation of Ketone-Derived Benzoylhydrazones: Practical Synthesis of Tertiary Carbinamines","volume":"126","author":"Berger","year":"2004","journal-title":"J. Am. Chem. Soc."},{"key":"2026081306015202800_cit25","unstructured":"Sun\n              X.-W.\n            \n           Ph. D. Dissertation, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 2007."},{"key":"2026081306015202800_cit26","doi-asserted-by":"crossref","first-page":"1588","DOI":"10.1021\/jo052298n","article-title":"Highly Diastereoselective Enolate Addition of O-Protected \u03b1-Hydroxyacetate to (SR)-tert-Butanesulfinylimines: Synthesis of Taxol Side Chain","volume":"71","author":"Wang","year":"2006","journal-title":"J. Org. Chem."},{"key":"2026081306015202800_cit27","unstructured":"Liu\n              M.\n            \n           M.S. Dissertation, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 2007."},{"key":"2026081306015202800_cit28a","doi-asserted-by":"crossref","first-page":"1052","DOI":"10.1021\/jo981922b","article-title":"Cytoxazone: A Novel Cytokine Modulator Containing a 2-Oxazolidinone Ring Produced by Streptomyces sp","volume":"64","author":"Kakeya","year":"1999","journal-title":"J. Org. Chem."},{"key":"2026081306015202800_cit28b","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1021\/ol062752p","article-title":"Synthesis of 2-Oxazolidinones from \u03b2-Lactams: Stereospecific Total Synthesis of (\u2212)-Cytoxazone and All of Its Stereoisomers","volume":"9","author":"Mishra","year":"2007","journal-title":"Org. Lett."},{"key":"2026081306015202800_cit29","doi-asserted-by":"crossref","first-page":"1259","DOI":"10.1021\/ol8001514","article-title":"Remarkable Salt Effect on In-Mediated Allylation of N-tert-Butanesulfinyl Imines in Aqueous Media: Highly Practical Asymmetric Synthesis of Chiral Homoallylic Amines and Isoindolines","volume":"10","author":"Sun","year":"2008","journal-title":"Org. Lett."},{"key":"2026081306015202800_cit30a","doi-asserted-by":"crossref","first-page":"1261","DOI":"10.2174\/1385272054863961","article-title":"Approaches to the Formation of Condensed Isoindolones","volume":"9","author":"Csende","year":"2005","journal-title":"Curr. Org. Chem."},{"key":"2026081306015202800_cit30b","doi-asserted-by":"crossref","first-page":"5336","DOI":"10.1021\/ja0710914","article-title":"Design of C2-Symmetric Tetrahydropentalenes as New Chiral Diene Ligands for Highly Enantioselective Rh-Catalyzed Arylation of N-Tosylarylimines with Arylboronic Acids","volume":"129","author":"Wang","year":"2007","journal-title":"J. Am. Chem. 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